This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Ataxin 2
catalog :
21776-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; human; loading ...; fig 1s2e
Zhang P, Fan B, Yang P, Temirov J, Messing J, Kim H, et al. Chronic optogenetic induction of stress granules is cytotoxic and reveals the evolution of ALS-FTD pathology. elife. 2019;8: pubmed publisher
Shelkovnikova T, An H, Skelt L, Tregoning J, Humphreys I, Buchman V. Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis. Cell Rep. 2019;29:4496-4508.e4 pubmed publisher
Lu Y, Dai J, Kong N, Liu J, Gong J, Yao Y. Internalization Characterization of Si Nanorod with Camouflaged Cell Membrane Proteins Reveals ATXN2 as a Negative Regulator. Cells. 2019;8: pubmed publisher
Park S, Park S, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova T, et al. Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies. PLoS Genet. 2019;15:e1008308 pubmed publisher
Şen N, Canet Pons J, Halbach M, Arsovic A, Pilatus U, Chae W, et al. Generation of an Atxn2-CAG100 knock-in mouse reveals N-acetylaspartate production deficit due to early Nat8l dysregulation. Neurobiol Dis. 2019;132:104559 pubmed publisher
Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed publisher
Mann J, Gleixner A, Mauna J, Gomes E, DeChellis Marks M, Needham P, et al. RNA Binding Antagonizes Neurotoxic Phase Transitions of TDP-43. Neuron. 2019;102:321-338.e8 pubmed publisher
Chew J, Cook C, Gendron T, Jansen West K, Del Rosso G, Daughrity L, et al. Aberrant deposition of stress granule-resident proteins linked to C9orf72-associated TDP-43 proteinopathy. Mol Neurodegener. 2019;14:9 pubmed publisher
Zhang Y, Guo L, Gonzales P, Gendron T, Wu Y, Jansen West K, et al. Heterochromatin anomalies and double-stranded RNA accumulation underlie C9orf72 poly(PR) toxicity. Science. 2019;363: pubmed publisher
Ostrowski L, Hall A, Szafranski K, Oshidari R, Abraham K, Chan J, et al. Conserved Pbp1/Ataxin-2 regulates retrotransposon activity and connects polyglutamine expansion-driven protein aggregation to lifespan-controlling rDNA repeats. Commun Biol. 2018;1:187 pubmed publisher
Halbach M, Gispert S, Stehning T, Damrath E, Walter M, Auburger G. Atxn2 Knockout and CAG42-Knock-in Cerebellum Shows Similarly Dysregulated Expression in Calcium Homeostasis Pathway. Cerebellum. 2017;16:68-81 pubmed publisher
product information
CatalogNo :
21776-1-AP
AntigenName :
Ataxin 2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
ataxin 2
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ataxin 2, ATX2, ATXN2, SCA2, TNRC13
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC114546
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:1000 ; WB 1:8000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.