APAF1 | Proteintech Group 21710-1-AP product information

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product summary

company name :

Proteintech Group

product type :

antibody

product name :

APAF1

catalog :

21710-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 22

Reference
Wang X, Lin Y, Zheng Y. Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration. Mol Med Rep. 2020;22:2318-2328 pubmed publisher
Huang J, Bao D, Lei C, Tang H, Zhang C, Su H, et al. Selenoprotein T protects against cisplatin-induced acute kidney injury through suppression of oxidative stress and apoptosis. FASEB J. 2020;: pubmed publisher
Chen B, Wen P, Hu G, Gao Y, Qi X, Zhu K, et al. Antagonizing CDK8 Sensitizes Colorectal Cancer to Radiation Through Potentiating the Transcription of e2f1 Target Gene apaf1. Front Cell Dev Biol. 2020;8:408 pubmed publisher
Su Q, Wang J, Liu F, Zhang Y. Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis. Toxicol In Vitro. 2020;66:104840 pubmed publisher
Yang N, Li C, Li H, Liu M, Cai X, Cao F, et al. Emodin Induced SREBP1-Dependent and SREBP1-Independent Apoptosis in Hepatocellular Carcinoma Cells. Front Pharmacol. 2019;10:709 pubmed publisher
Gao Y, Yin H, Zhang Y, Dong Y, Yang F, Wu X, et al. Dexmedetomidine protects hippocampal neurons against hypoxia/reoxygenation-induced apoptosis through activation HIF-1α/p53 signaling. Life Sci. 2019;232:116611 pubmed publisher
Zhao L, Zhuang J, Wang Y, Zhou D, Zhao D, Zhu S, et al. Propofol Ameliorates H9c2 Cells Apoptosis Induced by Oxygen Glucose Deprivation and Reperfusion Injury via Inhibiting High Levels of Mitochondrial Fusion and Fission. Front Pharmacol. 2019;10:61 pubmed publisher
Zheng L, Hu Y, Zhao X, Yin L, Xu L, Qi Y, et al. Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis. Pharmacol Res. 2019;139:431-439 pubmed publisher
Wang R, Dong Y, Lu Y, Zhang W, Brann D, Zhang Q. Photobiomodulation for Global Cerebral Ischemia: Targeting Mitochondrial Dynamics and Functions. Mol Neurobiol. 2019;56:1852-1869 pubmed publisher
Chen X, Liu C, Zhao R, Zhao P, Wu J, Zhou N, et al. Synergetic and Antagonistic Molecular Effects Mediated by the Feedback Loop of p53 and JNK between Saikosaponin D and SP600125 on Lung Cancer A549 Cells. Mol Pharm. 2018;15:4974-4984 pubmed publisher
Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, et al. Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway. J Agric Food Chem. 2018;66:9704-9718 pubmed publisher
Xu D, Guo Y, Zhang M, Sun Y. The subsequent biological effects of simulated microgravity on endothelial cell growth in HUVECs. Chin J Traumatol. 2018;21:229-237 pubmed publisher
Liu Y, Ren L, Liu W, Xiao Z. MiR-21 regulates the apoptosis of keloid fibroblasts by caspase-8 and the mitochondria-mediated apoptotic signaling pathway via targeting FasL. Biochem Cell Biol. 2018;96:548-555 pubmed publisher
Wang Y, Zhang Q, Zhong L, Lin M, Luo X, Liu S, et al. Apoptotic Protease Activating Factor-1 Inhibitor Mitigates Myocardial Ischemia Injury via Disturbing Procaspase-9 Recruitment by Apaf-1. Oxid Med Cell Longev. 2017;2017:9747296 pubmed publisher
Du J, Zhang X, Han J, Man K, Zhang Y, Chu E, et al. Pro-Inflammatory CXCR3 Impairs Mitochondrial Function in Experimental Non-Alcoholic Steatohepatitis. Theranostics. 2017;7:4192-4203 pubmed publisher
Duan H, Wang R, Yan X, Liu H, Zhang Y, Mu D, et al. Phloretin induces apoptosis of human esophageal cancer via a mitochondria-dependent pathway. Oncol Lett. 2017;14:6763-6768 pubmed publisher
Zhang S, Yao F, Jing T, Zhang M, Zhao W, Zou X, et al. Cloning, expression pattern, and potential role of apoptosis inhibitor 5 in the termination of embryonic diapause and early embryo development of Artemia sinica. Gene. 2017;628:170-179 pubmed publisher
Su W, Lin Y, Yu X, Wang Y, Lin X, Su Q, et al. Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid. J Agric Food Chem. 2017;65:5620-5631 pubmed publisher
Li S, Xu D, Guo J, Sun Y. Inhibition of cell growth and induction of inflammation by endosulfan in HUVEC-C cells. Environ Toxicol. 2016;31:1785-1795 pubmed publisher
Zhang H, Xue J, Zhang Z, Kong H, Liu A, Li S, et al. Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis. Brain Res. 2015;1622:474-83 pubmed publisher
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, et al. DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway. Med Oncol. 2015;32:115 pubmed publisher
Shi J, Ren C, Liu H, Wang L, Zhu B, Huang W, et al. An ESRG-interacting protein, COXII, is involved in pro-apoptosis of human embryonic stem cells. Biochem Biophys Res Commun. 2015;460:130-5 pubmed publisher

product information

CatalogNo :

21710-1-AP

AntigenName :

APAF1

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

apoptotic peptidase activating factor 1

Immunogen :

Fusion Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

APAF 1, APAF1, CED4, KIAA0413

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC136532

Category :

Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

AppTiter :

IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:1000 ;