This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SMARCA4/BRG1
catalog :
21634-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, chromatin immunoprecipitation, RNA immunoprecipitation
citations: 14
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:250; loading ...; fig 4
Marquez Vilendrer S, Rai S, Gramling S, Lu L, Reisman D. BRG1 and BRM loss selectively impacts RB and P53, respectively: BRG1 and BRM have differential functions in vivo. Oncoscience. 2016;3:337-350 pubmed publisher
  • RNA immunoprecipitation; human; 1:500; loading ...; fig 3f
  • immunohistochemistry; human; 1:500; loading ...; fig 7j
  • western blot; human; 1:500; loading ...; fig 4b
Zhu P, Wang Y, Wu J, Huang G, Liu B, Ye B, et al. LncBRM initiates YAP1 signalling activation to drive self-renewal of liver cancer stem cells. Nat Commun. 2016;7:13608 pubmed publisher
Tu J, Liu X, Jia H, Reilly J, Yu S, Cai C, et al. The chromatin remodeler Brg1 is required for formation and maintenance of hematopoietic stem cells. FASEB J. 2020;: pubmed publisher
Sun X, Yu W, Li L, Sun Y. ADNP Controls Gene Expression Through Local Chromatin Architecture by Association With BRG1 and CHD4. Front Cell Dev Biol. 2020;8:553 pubmed publisher
Wu S, Ge Y, Li X, Yang Y, Zhou H, Lin K, et al. BRM-SWI/SNF chromatin remodeling complex enables functional telomeres by promoting co-expression of TRF2 and TRF1. PLoS Genet. 2020;16:e1008799 pubmed publisher
Zhu X, Lan B, Yi X, He C, Dang L, Zhou X, et al. HRP2-DPF3a-BAF complex coordinates histone modification and chromatin remodeling to regulate myogenic gene transcription. Nucleic Acids Res. 2020;48:6563-6582 pubmed publisher
Shi D, Shi X, Xing K, Zhou H, Lu L, Wu W. miR-296-5p suppresses stem cell potency of hepatocellular carcinoma cells via regulating Brg1/Sall4 axis. Cell Signal. 2020;72:109650 pubmed publisher
Ganguly D, Sims M, Cai C, Fan M, Pfeffer L. Chromatin Remodeling Factor BRG1 Regulates Stemness and Chemosensitivity of Glioma Initiating Cells. Stem Cells. 2018;36:1804-1815 pubmed publisher
Tibshirani M, Zhao B, Gentil B, Minotti S, Marques C, Keith J, et al. Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis. Hum Mol Genet. 2017;26:4142-4152 pubmed publisher
de Castro R, Previato L, Goitea V, Felberg A, Guiraldelli M, Filiberti A, et al. The chromatin-remodeling subunit Baf200 promotes homology-directed DNA repair and regulates distinct chromatin-remodeling complexes. J Biol Chem. 2017;292:8459-8471 pubmed publisher
Marquez Vilendrer S, Rai S, Gramling S, Lu L, Reisman D. Loss of the SWI/SNF ATPase subunits BRM and BRG1 drives lung cancer development. Oncoscience. 2016;3:322-336 pubmed publisher
Marquez Vilendrer S, Thompson K, Lu L, Reisman D. Mechanism of BRG1 silencing in primary cancers. Oncotarget. 2016;7:56153-56169 pubmed publisher
Araujo L, Timmers C, Bell E, Shilo K, Lammers P, Zhao W, et al. Genomic Characterization of Non-Small-Cell Lung Cancer in African Americans by Targeted Massively Parallel Sequencing. J Clin Oncol. 2015;33:1966-73 pubmed publisher
Wang Y, He L, Du Y, Zhu P, Huang G, Luo J, et al. The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling. Cell Stem Cell. 2015;16:413-25 pubmed publisher
product information
CatalogNo :
21634-1-AP
AntigenName :
SMARCA4/BRG1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
Immunogen :
Fusion Protein
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, CoIP, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ATP dependent helicase SMARCA4, BAF190, BAF190A, BRG1, BRG1 associated factor 190A, hSNF2b, Protein brahma homolog 1, Protein BRG 1, SMARCA4, SNF2, SNF2 BETA, SNF2B, SNF2L4, SNF2LB, SWI2, Transcription activator BRG1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC150298
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:400 ; IP 1:1000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.