This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ER
catalog :
21244-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, bovine
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 42
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 6a
Zhou X, Cai D, Xiao S, Ning M, Zhou R, Zhang S, et al. InvivoPen: A novel plasma source for in vivo cancer treatment. J Cancer. 2020;11:2273-2282 pubmed publisher
  • immunohistochemistry - paraffin section; bovine; 1:50; fig 6
Ideta A, Yamashita S, Seki Soma M, Yamaguchi R, Chiba S, Komaki H, et al. Generation of exogenous germ cells in the ovaries of sterile NANOS3-null beef cattle. Sci Rep. 2016;6:24983 pubmed publisher
Long X, Gao Y, Liu W, Liu X, Hayashi T, Mizuno K, et al. Natural flavonoid silibinin promotes the migration and myogenic differentiation of murine C2C12 myoblasts via modulation of ROS generation and down-regulation of estrogen receptor α expression. Mol Cell Biochem. 2020;: pubmed publisher
Wang X, Lin Y, Zheng Y. Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration. Mol Med Rep. 2020;22:2318-2328 pubmed publisher
Zhang W, Guo Y, Wang K, Chen L, Jiang P. Neuroprotective effects of vitamin D and 17ß-estradiol against ovariectomy-induced neuroinflammation and depressive-like state: Role of the AMPK/NF-κB pathway. Int Immunopharmacol. 2020;86:106734 pubmed publisher
Tang J, Luo Y, Tian Z, Liao X, Cui Q, Yang Q, et al. TRIM11 promotes breast cancer cell proliferation by stabilizing estrogen receptor α. Neoplasia. 2020;22:343-351 pubmed publisher
Wang J, Zhang X, Zhang L, Yan T, Wu B, Xu F, et al. Silychristin A activates Nrf2-HO-1/SOD2 pathway to reduce apoptosis and improve GLP-1 production through upregulation of estrogen receptor α in GLUTag cells. Eur J Pharmacol. 2020;881:173236 pubmed publisher
Lin L, Luo X, Wang L, Xu F, He Y, Wang Q, et al. BML-111 inhibits EMT, migration and metastasis of TAMs-stimulated triple-negative breast cancer cells via ILK pathway. Int Immunopharmacol. 2020;85:106625 pubmed publisher
Sun M, Sun B, Qiao S, Feng X, Li Y, Zhang S, et al. Elevated maternal androgen is associated with dysfunctional placenta and lipid disorder in newborns of mothers with polycystic ovary syndrome. Fertil Steril. 2020;113:1275-1285.e2 pubmed publisher
Luo Y, Kishi S, Sasaki T, Ohmori H, Fujiwara Tani R, Mori S, et al. Targeting claudin-4 enhances chemosensitivity in breast cancer. Cancer Sci. 2020;111:1840-1850 pubmed publisher
Chen G, Zhang X, Chen H, Lin H, Wu H, Lin H, et al. miR-22 represses osteoblast viability with ESR1 presenting a direct target and indirectly inactivating p38 MAPK/JNK signaling. J Gene Med. 2020;22:e3174 pubmed publisher
Mei Y, Cai D, Dai X. Modulating cancer stemness provides luminal a breast cancer cells with HER2 positive-like features. J Cancer. 2020;11:1162-1169 pubmed publisher
Ren L, Liu W, Wang C, Yang Y, Huang X, Wang C, et al. The ancient Chinese formula Longdan Xiegan Tang improves antipsychotic-induced hyperprolactinemia by repairing the hypothalamic and pituitary TGF-β1 signaling in rats. J Ethnopharmacol. 2020;254:112572 pubmed publisher
Chu C, Gao X, Li X, Zhang X, Ma R, Jia Y, et al. Involvement of Estrogen Receptor-α in the Activation of Nrf2-Antioxidative Signaling Pathways by Silibinin in Pancreatic β-Cells. Biomol Ther (Seoul). 2020;28:163-171 pubmed publisher
Andrade F, Nguyen N, Warri A, Hilakivi Clarke L. Reversal of increased mammary tumorigenesis by valproic acid and hydralazine in offspring of dams fed high fat diet during pregnancy. Sci Rep. 2019;9:20271 pubmed publisher
Wu S, Huang D, Su X, Yan H, Wu J, Sun Z. Oral exposure to low-dose bisphenol A induces hyperplasia of dorsolateral prostate and upregulates EGFR expression in adult Sprague-Dawley rats. Toxicol Ind Health. 2019;35:647-659 pubmed publisher
Ren Y, Xu X, Mao C, Han K, Xu Y, Cao B, et al. RNF6 promotes myeloma cell proliferation and survival by inducing glucocorticoid receptor polyubiquitination. Acta Pharmacol Sin. 2019;: pubmed publisher
Dai X, Mei Y, Chen X, Cai D. ANLN and KDR Are Jointly Prognostic of Breast Cancer Survival and Can Be Modulated for Triple Negative Breast Cancer Control. Front Genet. 2019;10:790 pubmed publisher
Fan H, Chen S, Gao B, Ding S, Zhao Q, Li C, et al. Risk analysis of systemic levels of estrogen and adipokines as well as estrogen receptors from PBMCs in childbearing and perimenopausal women with obesity. Diabetes Metab Syndr Obes. 2019;12:1287-1295 pubmed publisher
Guo J, Wang Q, Zhang Y, Sun W, Zhang S, Li Y, et al. Functional daidzein enhances the anticancer effect of topotecan and reverses BCRP-mediated drug resistance in breast cancer. Pharmacol Res. 2019;147:104387 pubmed publisher
Li H, Wu W, He X, Cao C, Yu X, Zeng Y, et al. Applying vibration in early postmenopausal osteoporosis promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells and suppresses postmenopausal osteoporosis progression. Biosci Rep. 2019;39: pubmed publisher
Liu Z, Jiang Z, Gao Y, Wang L, Chen C, Wang X. TP53 Mutations Promote Immunogenic Activity in Breast Cancer. J Oncol. 2019;2019:5952836 pubmed publisher
Sun Y, Yang J, Liu W, Yao G, Xu F, Hayashi T, et al. Attenuating effect of silibinin on palmitic acid-induced apoptosis and mitochondrial dysfunction in pancreatic β-cells is mediated by estrogen receptor alpha. Mol Cell Biochem. 2019;: pubmed publisher
Liu L, Yan J, Ge F, Xu X, Lu J, Shi H, et al. Saikosaponin‑D improves fear memory deficits in ovariectomized rats via the action of estrogen receptor‑α in the hippocampus. Mol Med Rep. 2019;20:332-340 pubmed publisher
Ge L, Cui Y, Liu B, Yin X, Pang J, Han J. ERα and Wnt/β‑catenin signaling pathways are involved in angelicin‑dependent promotion of osteogenesis. Mol Med Rep. 2019;19:3469-3476 pubmed publisher
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Hattori S, et al. Silibinin protects rat pancreatic β-cell through up-regulation of estrogen receptors' signaling against amylin- or Aβ1-42 -induced reactive oxygen species/reactive nitrogen species generation. Phytother Res. 2019;33:998-1009 pubmed publisher
Wan S, Jiang J, Zheng C, Wang N, Zhai X, Fei X, et al. Estrogen nuclear receptors affect cell migration by altering sublocalization of AQP2 in glioma cell lines. Cell Death Discov. 2018;5:49 pubmed publisher
Ge L, Cui Y, Cheng K, Han J. Isopsoralen Enhanced Osteogenesis by Targeting AhR/ERα. Molecules. 2018;23: pubmed publisher
Zhu J, Jia Y, Luo Y, Huang D, Shao C, Li L, et al. Effect of maternal folic acid supplementation on prostatitis risk in the rat offspring. Int Urol Nephrol. 2018;50:1963-1973 pubmed publisher
Shen D, Tian L, Shen T, Sun H, Liu P. Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. Cell Physiol Biochem. 2018;47:2261-2277 pubmed publisher
Yang J, Sun Y, Xu F, Liu W, Hayashi T, Onodera S, et al. Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity. Biomed Pharmacother. 2018;102:344-353 pubmed publisher
Liu H, Zhong L, Zhang Y, Liu X, Li J. Rutin attenuates cerebral ischemia-reperfusion injury in ovariectomized rats via estrogen-receptor-mediated BDNF-TrkB and NGF-TrkA signaling. Biochem Cell Biol. 2018;96:672-681 pubmed publisher
Huang D, Zheng C, Pan Q, Wu S, Su X, Li L, et al. Oral exposure of low-dose bisphenol A promotes proliferation of dorsolateral prostate and induces epithelial-mesenchymal transition in aged rats. Sci Rep. 2018;8:490 pubmed publisher
Fan S, Liao Y, Liu C, Huang Q, Liang H, Ai B, et al. Estrogen promotes tumor metastasis via estrogen receptor beta-mediated regulation of matrix-metalloproteinase-2 in non-small cell lung cancer. Oncotarget. 2017;8:56443-56459 pubmed publisher
Li P, Gan Y, Xu Y, Wang L, Ouyang B, Zhang C, et al. 17beta-estradiol Attenuates TNF-?-Induced Premature Senescence of Nucleus Pulposus Cells through Regulating the ROS/NF-?B Pathway. Int J Biol Sci. 2017;13:145-156 pubmed publisher
Fu Y, Xiong J. MicroRNA-124 enhances response to radiotherapy in human epidermal growth factor receptor 2-positive breast cancer cells by targeting signal transducer and activator of transcription 3. Croat Med J. 2016;57:457-464 pubmed
Chen L, Lv D, Wang D, Chen X, Zhu Z, Cao Y, et al. A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement. Mol Biosyst. 2016;12:3347-3356 pubmed
Song L, Shen W, Zhang H, Wang Q, Wang Y, Zhou Z. Differential expression of androgen, estrogen, and progesterone receptors in benign prostatic hyperplasia. Bosn J Basic Med Sci. 2016;16:201-8 pubmed publisher
Qin Z, Zheng H, Zhou L, Ou Y, Huang B, Yan B, et al. Tsc1 deficiency impairs mammary development in mice by suppression of AKT, nuclear ERα, and cell-cycle-driving proteins. Sci Rep. 2016;6:19587 pubmed publisher
Zheng N, Liu L, Liu W, Zhang P, Huang H, Zang L, et al. ERβ up-regulation was involved in silibinin-induced growth inhibition of human breast cancer MCF-7 cells. Arch Biochem Biophys. 2016;591:141-9 pubmed publisher
Wang Q, Xu C, Zhao Y, Xu Z, Zhang Y, Jiang J, et al. miR-26b-3p Regulates Human Umbilical Cord-Derived Mesenchymal Stem Cell Proliferation by Targeting Estrogen Receptor. Stem Cells Dev. 2016;25:415-26 pubmed publisher
Fu C, Xu D, Wang C, Jin Y, Liu Q, Meng Q, et al. Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats. J Cell Physiol. 2015;230:2184-201 pubmed publisher
product information
CatalogNo :
21244-1-AP
AntigenName :
ER
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
estrogen receptor 1
Immunogen :
Fusion Protein
Species :
cow, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ER, ER alpha, Era, ESR, ESR1, ESRA, Estradiol receptor, Estrogen receptor, estrogen receptor 1, NR3A1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC128573
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:400 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.