This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MKL1
catalog :
21166-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, chromatin immunoprecipitation
citations: 11
Reference
Tang B, Tang M, Xu Q, Guo J, Xuan L, Zhou J, et al. MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α. J Biosci. 2020;45: pubmed
Chen B, Li Z, Feng Y, Wu X, Xu Y. Myocardin-related transcription factor A (MRTF-A) mediates doxorubicin-induced PERP transcription in colon cancer cells. Biochem Biophys Res Commun. 2018;503:1732-1739 pubmed publisher
Li Z, Chen B, Dong W, Xu W, Song M, Fang M, et al. Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells. Biochim Biophys Acta Gene Regul Mech. 2018;: pubmed publisher
Meng C, He Y, Wei Z, Lu Y, Du F, Ou G, et al. MRTF-A mediates the activation of COL1A1 expression stimulated by multiple signaling pathways in human breast cancer cells. Biomed Pharmacother. 2018;104:718-728 pubmed publisher
He H, Du F, He Y, Wei Z, Meng C, Xu Y, et al. The Wnt-β-catenin signaling regulated MRTF-A transcription to activate migration-related genes in human breast cancer cells. Oncotarget. 2018;9:15239-15251 pubmed publisher
Fernández Barrera J, Bernabé Rubio M, Casares Arias J, Rangel L, Fernández Martín L, Correas I, et al. The actin-MRTF-SRF transcriptional circuit controls tubulin acetylation via α-TAT1 gene expression. J Cell Biol. 2018;217:929-944 pubmed publisher
Luo Y, Xu Y, Wang Z, Li X, Xing W, Zhang T. The Synergy of Two Factors on Insulin Expression. Cell Reprogram. 2018;20:49-54 pubmed publisher
Yao Y, Hu Z, Ye J, Hu C, Song Q, Da X, et al. Targeting AGGF1 (angiogenic factor with G patch and FHA domains 1) for Blocking Neointimal Formation After Vascular Injury. J Am Heart Assoc. 2017;6: pubmed publisher
He H, Wei Z, Du F, Meng C, Zheng D, Lai Y, et al. Transcription of HOTAIR is regulated by RhoC-MRTF-A-SRF signaling pathway in human breast cancer cells. Cell Signal. 2017;31:87-95 pubmed publisher
He H, Wang D, Yao H, Wei Z, Lai Y, Hu J, et al. Transcriptional factors p300 and MRTF-A synergistically enhance the expression of migration-related genes in MCF-7 breast cancer cells. Biochem Biophys Res Commun. 2015;467:813-20 pubmed publisher
Shu X, Zhang L, Zhang R, Zhang C, He H, Zhou H, et al. Histone acetyltransferase p300 promotes MRTF-A-mediates transactivation of VE-cadherin gene in human umbilical vein endothelial cells. Gene. 2015;563:17-23 pubmed publisher
product information
CatalogNo :
21166-1-AP
AntigenName :
MKL1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
megakaryoblastic leukemia (translocation) 1
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, chIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BSAC, KIAA1438, MAL, MKL/myocardin like protein 1, MKL1, MRTF A, MRTFA, MRTF-A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC115039
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:50 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.