This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CHCHD4
catalog :
21090-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Reference
Gao F, Zhang Y, Hou X, Tao Z, Ren H, Wang G. Dependence of PINK1 accumulation on mitochondrial redox system. Aging Cell. 2020;:e13211 pubmed publisher
Singh R, Jeyaraju D, Voisin V, Hurren R, Xu C, Hawley J, et al. Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal. Cell Stem Cell. 2020;26:926-937.e10 pubmed publisher
Babbar M, Huang Y, Curtiss C, Sheikh M. CHTM1 regulates cancer cell sensitivity to metabolic stress via p38-AIF1 pathway. J Exp Clin Cancer Res. 2019;38:271 pubmed publisher
Lehmer C, Schludi M, Ransom L, Greiling J, Junghänel M, Exner N, et al. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. EMBO Mol Med. 2018;10: pubmed publisher
Wischhof L, Gioran A, Sonntag Bensch D, Piazzesi A, Stork M, Nicotera P, et al. A disease-associated Aifm1 variant induces severe myopathy in knockin mice. Mol Metab. 2018;13:10-23 pubmed publisher
Babbar M, Huang Y, An J, Landas S, Sheikh M. CHTM1, a novel metabolic marker deregulated in human malignancies. Oncogene. 2018;37:2052-2066 pubmed publisher
Télot L, Rousseau E, Lesuisse E, García C, Morlet B, Léger T, et al. Quantitative proteomics in Friedreich's ataxia B-lymphocytes: A valuable approach to decipher the biochemical events responsible for pathogenesis. Biochim Biophys Acta Mol Basis Dis. 2018;1864:997-1009 pubmed publisher
Song G, Napoli E, Wong S, Hagerman R, Liu S, Tassone F, et al. Altered redox mitochondrial biology in the neurodegenerative disorder fragile X-tremor/ataxia syndrome: use of antioxidants in precision medicine. Mol Med. 2016;22: pubmed publisher
Balogh T, Lőrincz T, Stiller I, Mandl J, Bánhegyi G, Szarka A. The Level of ALR is Regulated by the Quantity of Mitochondrial DNA. Pathol Oncol Res. 2016;22:431-7 pubmed publisher
Meyer K, Buettner S, Ghezzi D, Zeviani M, Bano D, Nicotera P. Loss of apoptosis-inducing factor critically affects MIA40 function. Cell Death Dis. 2015;6:e1814 pubmed publisher
Aras S, Bai M, Lee I, Springett R, Hüttemann M, Grossman L. MNRR1 (formerly CHCHD2) is a bi-organellar regulator of mitochondrial metabolism. Mitochondrion. 2015;20:43-51 pubmed publisher
product information
CatalogNo :
21090-1-AP
AntigenName :
CHCHD4
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
coiled-coil-helix-coiled-coil-helix domain containing 4
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CHCHD4, MIA40
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC033775
Category :
Cytoskeleton/Scaffold Proteins;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:200 ; IP 1:1000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.