This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SHH
catalog :
20697-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry
citations: 24
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 3
Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, et al. Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling. Front Pharmacol. 2020;11:204 pubmed publisher
  • western blot; human; loading ...; fig 4b
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, et al. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells. Oncol Lett. 2019;18:3081-3091 pubmed publisher
Yin S, Bai X, Xin D, Li T, Chu X, Ke H, et al. Neuroprotective Effects of the Sonic Hedgehog Signaling Pathway in Ischemic Injury through Promotion of Synaptic and Neuronal Health. Neural Plast. 2020;2020:8815195 pubmed publisher
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, et al. Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway. Nutr Cancer. 2020;:1-11 pubmed publisher
Zhao G, Li H, Guo Q, Zhou A, Wang X, Li P, et al. Exosomal Sonic Hedgehog derived from cancer-associated fibroblasts promotes proliferation and migration of esophageal squamous cell carcinoma. Cancer Med. 2020;9:2500-2513 pubmed publisher
Wu M, Gao F, Yang X, Qin X, Chen G, Li D, et al. Matrix metalloproteinase-9 regulates the blood brain barrier via the hedgehog pathway in a rat model of traumatic brain injury. Brain Res. 2019;:146553 pubmed publisher
Li J, Zong D, Chen Y, Chen P. Anti-apoptotic effect of the Shh signaling pathway in cigarette smoke extract induced MLE 12 apoptosis. Tob Induc Dis. 2019;17:49 pubmed publisher
Zhang Q, Cao W, Wang X, Zhang M, Lu X, Chen J, et al. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Phytother Res. 2019;: pubmed publisher
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, et al. TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling. Nat Commun. 2019;10:2863 pubmed publisher
Kleene R, Loers G, Jakovcevski I, Mishra B, Schachner M. Histone H1 improves regeneration after mouse spinal cord injury and changes shape and gene expression of cultured astrocytes. Restor Neurol Neurosci. 2019;37:291-313 pubmed publisher
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed publisher
Zhang H, Nan W, Wang S, Song X, Si H, Li T, et al. Epigallocatechin-3-Gallate Promotes the Growth of Mink Hair Follicles Through Sonic Hedgehog and Protein Kinase B Signaling Pathways. Front Pharmacol. 2018;9:674 pubmed publisher
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, et al. Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells. Int J Oncol. 2018;52:1787-1800 pubmed publisher
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, et al. Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway. Oncogenesis. 2018;7:24 pubmed publisher
Chen J, Li H, Lim G, McCabe M, Zhao W, Yang Y, et al. Different effects of dexmedetomidine and midazolam on the expression of NR2B and GABAA-α1 following peripheral nerve injury in rats. IUBMB Life. 2018;70:143-152 pubmed publisher
Zhuang H, Cao G, Kou C, Liu T. CCL2/CCR2 axis induces hepatocellular carcinoma invasion and epithelial-mesenchymal transition in vitro through activation of the Hedgehog pathway. Oncol Rep. 2018;39:21-30 pubmed publisher
Matsumoto K, Shimo T, Kurio N, Okui T, Ibaragi S, Kunisada Y, et al. Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling. J Cell Biochem. 2018;119:4352-4360 pubmed publisher
Wu X, Yang B, Hu Y, Sun R, Wang H, Fu J, et al. NRF2 Is a Potential Modulator of Hyperresistance to Arsenic Toxicity in Stem-Like Keratinocytes. Oxid Med Cell Longev. 2017;2017:7417694 pubmed publisher
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, et al. Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway. Biochem Biophys Res Commun. 2017;493:521-527 pubmed publisher
Zhu J, Yang X, Chen Y, Jiang Y, Wang S, Li Y, et al. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/?-catenin and Sonic Hedgehog Pathways. Phytother Res. 2017;31:680-688 pubmed publisher
Hu Q, Li T, Wang L, Xie Y, Liu S, Bai X, et al. Neuroprotective Effects of a Smoothened Receptor Agonist against Early Brain Injury after Experimental Subarachnoid Hemorrhage in Rats. Front Cell Neurosci. 2016;10:306 pubmed publisher
Liu Q, Jiang M, Kuang Y, Shu X, Li J, Li M, et al. Dicer1 Ablation Impairs Responsiveness of Cerebellar Granule Neuron Precursors to Sonic Hedgehog and Disrupts Expression of Distinct Cell Cycle Regulator Genes. Cerebellum. 2017;16:450-461 pubmed publisher
Su C, Zhang B, Liu W, Zheng H, Sun L, Tong J, et al. High extracellular pressure promotes gastric cancer cell adhesion, invasion, migration and suppresses gastric cancer cell differentiation. Oncol Rep. 2016;36:1048-54 pubmed publisher
Pang P, Shimo T, Takada H, Matsumoto K, Yoshioka N, Ibaragi S, et al. Expression pattern of sonic hedgehog signaling and calcitonin gene-related peptide in the socket healing process after tooth extraction. Biochem Biophys Res Commun. 2015;467:21-6 pubmed publisher
product information
CatalogNo :
20697-1-AP
AntigenName :
SHH
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sonic hedgehog homolog (Drosophila)
Immunogen :
Peptide
Species :
american minks, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
HHG 1, HHG1, HLP3, HPE3, MCOPCB5, SHH, SMMCI, Sonic hedgehog protein, TPT, TPTPS
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000193
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:200 ; IP 1:500 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.