This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PSD95-Specific,DLG4
catalog :
20665-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 38
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry; mouse; 1:100; loading ...; tbl 3
Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, et al. Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling. Front Pharmacol. 2020;11:204 pubmed publisher
  • immunohistochemistry - paraffin section; rat; 1:25; loading ...; fig 6a
  • western blot; rat; 1:1000; loading ...; fig 6d
Li C, Liu W, Li X, Zhang Z, Qi H, Liu S, et al. The novel GLP-1/GIP analogue DA5-CH reduces tau phosphorylation and normalizes theta rhythm in the icv. STZ rat model of AD. Brain Behav. 2020;10:e01505 pubmed publisher
  • western blot; mouse; loading ...; fig 7b
Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, et al. Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease. Aging (Albany NY). 2019;11:7257-7273 pubmed publisher
Dong Y, Hong W, Tang Z, Gao Y, Wu X, Liu H. Dexmedetomidine Attenuates Neurotoxicity in Developing Rats Induced by Sevoflurane through Upregulating BDNF-TrkB-CREB and Downregulating ProBDNF-P75NRT-RhoA Signaling Pathway. Mediators Inflamm. 2020;2020:5458061 pubmed publisher
Zhang X, Zhao D, Wu W, Ali Shah S, Lai M, Yang D, et al. Melatonin regulates mitochondrial dynamics and alleviates neuron damage in prion diseases. Aging (Albany NY). 2020;12:11139-11151 pubmed publisher
Kukharsky M, Ninkina N, An H, Telezhkin V, Wei W, Meritens C, et al. Long non-coding RNA Neat1 regulates adaptive behavioural response to stress in mice. Transl Psychiatry. 2020;10:171 pubmed publisher
Zhu S, Min D, Zeng J, Ju Y, Liu Y, Chen X. Transplantation of Stem Cells from Human Exfoliated Deciduous Teeth Decreases Cognitive Impairment from Chronic Cerebral Ischemia by Reducing Neuronal Apoptosis in Rats. Stem Cells Int. 2020;2020:6393075 pubmed publisher
Ye Q, Zeng C, Luo C, Wu Y. Ferrostatin-1 mitigates cognitive impairment of epileptic rats by inhibiting P38 MAPK activation. Epilepsy Behav. 2020;103:106670 pubmed publisher
Yang F, Zhang Y, Tang Z, Shan Y, Wu X, Liu H. Hemin treatment protects neonatal rats from sevoflurane-induced neurotoxicity via the phosphoinositide 3-kinase/Akt pathway. Life Sci. 2020;242:117151 pubmed publisher
Shi B, Luo J, Fang Y, Liu X, Rao Z, Liu R, et al. Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves. Front Pharmacol. 2019;10:1324 pubmed publisher
Cao C, Zhou J, Wu X, Qian Y, Hong Y, Mu J, et al. Activation of CRHR1 contributes to cerebral endothelial barrier impairment via cPLA2 phosphorylation in experimental ischemic stroke. Cell Signal. 2019;66:109467 pubmed publisher
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, et al. SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. Cell Rep. 2019;28:78-90.e6 pubmed publisher
Li P, Guo Y, Ding P, Liu R, Deng F, Feng X, et al. Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats. Neurol Res. 2019;:1-8 pubmed publisher
Guo H, Xie Q, Cui J, Xu D, Deji C, Chen Y, et al. Naloxone reversed cognitive impairments induced by repeated morphine under heavy perceptual load in the 5-choice serial reaction time task. J Neurosci Res. 2019;: pubmed publisher
Kool M, Onori M, Borgesius N, van de Bree J, Elgersma Hooisma M, Nio E, et al. CAMK2-dependent signaling in neurons is essential for survival. J Neurosci. 2019;: pubmed publisher
Shah S, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, et al. Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Cheng Y, Yin B, Hou T, Chen T, Ping J. The overexpression of GRASP might inhibit cell proliferation and invasion in hepatocellular carcinoma. J Cell Physiol. 2019;: pubmed publisher
Yan X, Yang Z, Jia J, Song W, Fang X, Cai Z, et al. Protective mechanism of testosterone on cognitive impairment in a rat model of Alzheimer's disease. Neural Regen Res. 2019;14:649-657 pubmed publisher
Wang Y, Liu Y, Li Y, Liu B, Wu P, Xu S, et al. Protective effects of astaxanthin on subarachnoid hemorrhage-induced early brain injury: Reduction of cerebral vasospasm and improvement of neuron survival and mitochondrial function. Acta Histochem. 2019;121:56-63 pubmed publisher
Mo J, Wang B, Zhu X, Wu X, Liu Y. PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats. Neurobiol Dis. 2019;121:274-285 pubmed publisher
Cao C, Dai L, Mu J, Wang X, Hong Y, Zhu C, et al. S1PR2 antagonist alleviates oxidative stress-enhanced brain endothelial permeability by attenuating p38 and Erk1/2-dependent cPLA2 phosphorylation. Cell Signal. 2019;53:151-161 pubmed publisher
Jiang P, Li G, Zhou X, Wang C, Qiao Y, Liao D, et al. Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway. Chemosphere. 2019;214:430-435 pubmed publisher
Jia J, Yan X, Song W, Fang X, Cai Z, Huo D, et al. The protective mechanism underlying phenylethanoid glycosides (PHG) actions on synaptic plasticity in rat Alzheimer's disease model induced by beta amyloid 1-42. J Toxicol Environ Health A. 2018;81:1098-1107 pubmed publisher
Dang R, Qi J, Liu A, Ren Q, Lv D, Han L, et al. Regulation of hippocampal long term depression by Neuroligin 1. Neuropharmacology. 2018;143:205-216 pubmed publisher
Raihan O, Brishti A, Molla M, Li W, Zhang Q, Xu P, et al. The Age-dependent Elevation of miR-335-3p Leads to Reduced Cholesterol and Impaired Memory in Brain. Neuroscience. 2018;390:160-173 pubmed publisher
Yang Q, Zheng F, Hu Y, Yang Y, Li Y, Chen G, et al. ZDHHC8 critically regulates seizure susceptibility in epilepsy. Cell Death Dis. 2018;9:795 pubmed publisher
Chavez Valdez R, Emerson P, Goffigan Holmes J, Kirkwood A, Martin L, Northington F. Delayed injury of hippocampal interneurons after neonatal hypoxia-ischemia and therapeutic hypothermia in a murine model. Hippocampus. 2018;28:617-630 pubmed publisher
Wu Z, Li X, Zhang Y, Tong D, Wang L, Zhao P. Effects of Sevoflurane Exposure During Mid-Pregnancy on Learning and Memory in Offspring Rats: Beneficial Effects of Maternal Exercise. Front Cell Neurosci. 2018;12:122 pubmed publisher
Reddy P, Yin X, Manczak M, Kumar S, Pradeepkiran J, Vijayan M, et al. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease. Hum Mol Genet. 2018;27:2502-2516 pubmed publisher
Zhu B, Zhao L, Luo D, Xu D, Tan T, Dong Z, et al. Furin promotes dendritic morphogenesis and learning and memory in transgenic mice. Cell Mol Life Sci. 2018;75:2473-2488 pubmed publisher
Li C, Wang D, Wu W, Yang W, Ali Shah S, Zhao Y, et al. DLP1-dependent mitochondrial fragmentation and redistribution mediate prion-associated mitochondrial dysfunction and neuronal death. Aging Cell. 2018;17: pubmed publisher
Hui S, Yang Y, Peng W, Sheng C, Gong W, Chen S, et al. Protective effects of Bushen Tiansui decoction on hippocampal synapses in a rat model of Alzheimer's disease. Neural Regen Res. 2017;12:1680-1686 pubmed publisher
Sheng C, Xu P, Zhou K, Deng D, Zhang C, Wang Z. Icariin Attenuates Synaptic and Cognitive Deficits in an A?1-42-Induced Rat Model of Alzheimer's Disease. Biomed Res Int. 2017;2017:7464872 pubmed publisher
Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-?-Catenin Signaling in Prion Diseases Models. Front Mol Neurosci. 2017;10:128 pubmed publisher
Shah S, Zhao D, Taglialatela G, Khan S, Hussain T, Dong H, et al. Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters. Neurotherapeutics. 2017;14:463-483 pubmed publisher
Zhang Y, Chen G, Gao B, Li Y, Liang S, Wang X, et al. NR4A1 Knockdown Suppresses Seizure Activity by Regulating Surface Expression of NR2B. Sci Rep. 2016;6:37713 pubmed publisher
Chen Y, Kuo H, Bornschein U, Takahashi H, Chen S, Lu K, et al. Foxp2 controls synaptic wiring of corticostriatal circuits and vocal communication by opposing Mef2c. Nat Neurosci. 2016;19:1513-1522 pubmed publisher
Song Z, Zhu T, Zhou X, Barrow P, Yang W, Cui Y, et al. REST alleviates neurotoxic prion peptide-induced synaptic abnormalities, neurofibrillary degeneration and neuronal death partially via LRP6-mediated Wnt-β-catenin signaling. Oncotarget. 2016;7:12035-52 pubmed publisher
product information
CatalogNo :
20665-1-AP
AntigenName :
PSD95-Specific,DLG4
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
discs, large homolog 4 (Drosophila)
Immunogen :
Peptide
Species :
hamster, hamsters, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Disks large homolog 4, DLG4, PSD 95, PSD95, SAP 90, SAP90, Synapse associated protein 90
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_001365
Category :
Binding Proteins;Development;Membrane Proteins;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:500 ; IP 1:300 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.