This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
mTOR
catalog :
20657-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 103
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 7a, 7b
Ortega F, Roefs M, De Miguel Pérez D, Kooijmans S, de Jong O, Sluijter J, et al. Interfering with endolysosomal trafficking enhances release of bioactive exosomes. Nanomedicine. 2019;:102014 pubmed publisher
Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, et al. Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis. J Cell Physiol. 2020;: pubmed publisher
Liu Z, Ye S, Zhong X, Wang W, Lai C, Yang W, et al. Pretreatment with the ALDH2 activator Alda‑1 protects rat livers from ischemia/reperfusion injury by inducing autophagy. Mol Med Rep. 2020;22:2373-2385 pubmed publisher
Zhao Y, Tang J, Yang D, Tang C, Chen J. Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells. J Dairy Sci. 2020;103:8350-8359 pubmed publisher
Liu J, Hu Y, Feng Y, Jiang Y, Guo Y, Liu Y, et al. BDH2 triggers ROS-induced cell death and autophagy by promoting Nrf2 ubiquitination in gastric cancer. J Exp Clin Cancer Res. 2020;39:123 pubmed publisher
Liu J, Shangguan Y, Sun J, Cong W, Xie Y. BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways. Biomed Pharmacother. 2020;129:110414 pubmed publisher
Zhang S, Hamid M, Wang T, Liao J, Wen L, Zhou Y, et al. RSK-3 promotes cartilage regeneration via interacting with rpS6 in cartilage stem/progenitor cells. Theranostics. 2020;10:6915-6927 pubmed publisher
An Y, Zhang J, Cheng X, Li B, Tian Y, Zhang X, et al. miR-454 suppresses the proliferation and invasion of ovarian cancer by targeting E2F6. Cancer Cell Int. 2020;20:237 pubmed publisher
Wei A, Xiao H, Xu G, Yu X, Guo J, Jing Z, et al. Hyperoside Protects Human Umbilical Vein Endothelial Cells Against Anticardiolipin Antibody-Induced Injury by Activating Autophagy. Front Pharmacol. 2020;11:762 pubmed publisher
Mao K, Chen J, Yu H, Li H, Ren Y, Wu X, et al. Poly (ADP-ribose) polymerase 1 inhibition prevents neurodegeneration and promotes α-synuclein degradation via transcription factor EB-dependent autophagy in mutant α-synucleinA53T model of Parkinson's disease. Aging Cell. 2020;19:e13163 pubmed publisher
Zhou S, Ai Z, Li W, You P, Wu C, Li L, et al. Deciphering the Pharmacological Mechanisms of Taohe-Chengqi Decoction Extract Against Renal Fibrosis Through Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo. Front Pharmacol. 2020;11:425 pubmed publisher
Li J, Ma J, Tian Y, Zhao P, Liu X, Dong H, et al. Effective-component compatibility of Bufei Yishen formula II inhibits mucus hypersecretion of chronic obstructive pulmonary disease rats by regulating EGFR/PI3K/mTOR signaling. J Ethnopharmacol. 2020;257:112796 pubmed publisher
Jing X, Du L, Niu A, Wang Y, Wang Y, Wang C. Silencing of PRDX2 Inhibits the Proliferation and Invasion of Non-Small Cell Lung Cancer Cells. Biomed Res Int. 2020;2020:1276328 pubmed publisher
Meng C, Zhao Z, Bai R, Zhao W, Wang Y, Xue H, et al. MicroRNA‑22 mediates the cisplatin resistance of osteosarcoma cells by inhibiting autophagy via the PI3K/Akt/mTOR pathway. Oncol Rep. 2020;43:1169-1186 pubmed publisher
Xu H, Lin S, Gong Y, Huo Z, Zhao C, Zhu H, et al. Chaiyu-Dixian Formula Exerts Protective Effects on Ovarian Follicular Abnormal Development in Chronic Unpredictable Mild Stress (CUMS) Rat Model. Front Pharmacol. 2020;11:245 pubmed publisher
Xu H, Qu C, Gan L, Sun K, Tan J, Liu X, et al. Deletion of the Impg2 gene causes the degeneration of rod and cone cells in mice. Hum Mol Genet. 2020;29:1624-1634 pubmed publisher
Que Z, Luo B, Wang C, Qian F, Jiang Y, Li Y, et al. Proteomics analysis of tumor exosomes reveals vital pathways of Jinfukang inhibiting circulating tumor cells metastasis in lung cancer. J Ethnopharmacol. 2020;256:112802 pubmed publisher
Meng Q, Xue H. Knockdown of lncRNA OGFRP1 Inhibits Proliferation and Invasion of JEG-3 Cells Via AKT/mTOR Pathway. Technol Cancer Res Treat. 2020;19:1533033820905823 pubmed publisher
Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, et al. Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway. Mol Carcinog. 2020;59:575-589 pubmed publisher
Tan Y, Yin L, Sun Z, Shao S, Chen W, Man X, et al. Astragalus polysaccharide exerts anti-Parkinson via activating the PI3K/AKT/mTOR pathway to increase cellular autophagy level in vitro. Int J Biol Macromol. 2020;153:349-356 pubmed publisher
Zha A, Yuan D, Cui Z, Qi M, Liao S, Liao P, et al. The Evaluation of the Antioxidant and Intestinal Protective Effects of Baicalin-Copper in Deoxynivalenol-Challenged Piglets. Oxid Med Cell Longev. 2020;2020:5363546 pubmed publisher
Yang Z, Yu W, Liu B, Yang M, Tao H. Estrogen receptor β induces autophagy of osteosarcoma through the mTOR signaling pathway. J Orthop Surg Res. 2020;15:50 pubmed publisher
Wu Q, Zhang M, Liu X, Zhang J, Wang H. CB2R orchestrates neuronal autophagy through regulation of the mTOR signaling pathway in the hippocampus of developing rats with status epilepticus. Int J Mol Med. 2020;45:475-484 pubmed publisher
Wang Y, Zhao L, Han X, Wang Y, Mi J, Wang C, et al. Saikosaponin A Inhibits Triple-Negative Breast Cancer Growth and Metastasis Through Downregulation of CXCR4. Front Oncol. 2019;9:1487 pubmed publisher
Wang J, Wan D, Wan G, Wang J, Zhang J, Zhu H. Catalpol induces cell activity to promote axonal regeneration via the PI3K/AKT/mTOR pathway in vivo and in vitro stroke model. Ann Transl Med. 2019;7:756 pubmed publisher
Tang Z, Zhang Z, Zhang H, Wang Y, Zhang Y, Zhao J, et al. Autophagy Attenuation Hampers Progesterone Synthesis during the Development of Pregnant Corpus Luteum. Cells. 2019;9: pubmed publisher
Pan C, Liu Q, Wu X. HIF1α/miR-520a-3p/AKT1/mTOR Feedback Promotes The Proliferation And Glycolysis Of Gastric Cancer Cells. Cancer Manag Res. 2019;11:10145-10156 pubmed publisher
Wang J, Li L, Wang J, Song L, Tan N, Wang Z. Natural Naphthohydroquinone Dimer Rubioncolin C Exerts Anti-Tumor Activity by Inducing Apoptotic and Autophagic Cell Death and Inhibiting the NF-κB and Akt/mTOR/P70S6K Pathway in Human Cancer Cells. Cells. 2019;8: pubmed publisher
Liu J, Hu Y, Feng Y, Guo Y, Liu Y, Yang J, et al. Rafoxanide promotes apoptosis and autophagy of gastric cancer cells by suppressing PI3K /Akt/mTOR pathway. Exp Cell Res. 2019;385:111691 pubmed publisher
Zhu H, Miao Y, Shen Y, Guo J, Xie W, Zhao S, et al. The clinical characteristics and molecular mechanism of pituitary adenoma associated with meningioma. J Transl Med. 2019;17:354 pubmed publisher
Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, et al. Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis. Cell Prolif. 2019;:e12701 pubmed publisher
Sun J, Huang J, Lan J, Zhou K, Gao Y, Song Z, et al. Overexpression of CENPF correlates with poor prognosis and tumor bone metastasis in breast cancer. Cancer Cell Int. 2019;19:264 pubmed publisher
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed publisher
Dai B, Yu R, Fan M, Yang T, Wang B, Zhang Y. HMQ‑T‑F2 suppresses migration of the human cervical cancer HeLa cells by reversing EMT via the PI3K/Akt signaling pathway. Oncol Rep. 2019;: pubmed publisher
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, et al. Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells. Cell Biol Int. 2019;: pubmed publisher
Sayed A, Kotb A, Oda S, Kashiwada S, Mitani H. Protective effect of p53 knockout on 4-nonylphenol-induced nephrotoxicity in medaka (Oryzias latipes). Chemosphere. 2019;236:124314 pubmed publisher
Zhong W, Shi X, Yuan H, Bu H, Wu L, Wang R. Effects of Exercise Training on the Autophagy-Related Muscular Proteins Expression in Ovariectomized Rats. Front Physiol. 2019;10:735 pubmed publisher
Mao Z, Sang M, Chen C, Zhu W, Gong Y, Pei D. CSN6 Promotes the Migration and Invasion of Cervical Cancer Cells by Inhibiting Autophagic Degradation of Cathepsin L. Int J Biol Sci. 2019;15:1310-1324 pubmed publisher
Ye Z, Zhang S, Liu Y, Wang S, Zhang J, Huang R. A Peptide Analogue of Selectin Ligands Attenuated Atherosclerosis by Inhibiting Monocyte Activation. Mediators Inflamm. 2019;2019:8709583 pubmed publisher
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, et al. Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway. Am J Transl Res. 2019;11:2042-2055 pubmed
Chen C, Jiang L, Zhang M, Pan X, Peng C, Huang W, et al. Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy. Food Funct. 2019;10:2651-2657 pubmed publisher
Zheng R, Huang S, Zhu J, Lin W, Xu H, Zheng X. Leucine attenuates muscle atrophy and autophagosome formation by activating PI3K/AKT/mTOR signaling pathway in rotator cuff tears. Cell Tissue Res. 2019;: pubmed publisher
Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, et al. Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. Br J Pharmacol. 2019;176:919-937 pubmed publisher
Wang Y, Shao Y, Gao Y, Wan G, Wan D, Zhu H, et al. Catalpol prevents denervated muscular atrophy related to the inhibition of autophagy and reduces BAX/BCL2 ratio via mTOR pathway. Drug Des Devel Ther. 2019;13:243-253 pubmed publisher
Zhang X, Liu J, Gu Y, Sun C, Qu F. Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs. Cell Biol Int. 2019;43:158-166 pubmed publisher
Gong Y, Yang J, Cai J, Liu Q, Zhang J, Zhang Z. Effect of Gpx3 gene silencing by siRNA on apoptosis and autophagy in chicken cardiomyocytes. J Cell Physiol. 2019;234:7828-7838 pubmed publisher
Zhou G, Zhang G, Yuan Z, Pei R, Liu D. Has_circ_0008274 promotes cell proliferation and invasion involving AMPK/mTOR signaling pathway in papillary thyroid carcinoma. Eur Rev Med Pharmacol Sci. 2018;22:8772-8780 pubmed publisher
Suo L, Chang X, Zhao Y. The Orexin-A-Regulated Akt/mTOR Pathway Promotes Cell Proliferation Through Inhibiting Apoptosis in Pancreatic Cancer Cells. Front Endocrinol (Lausanne). 2018;9:647 pubmed publisher
Wang J, Yang C, Yuan Z, Yi J, Wu J. T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca2+Production. Int J Mol Sci. 2018;19: pubmed publisher
Yang Y, Sun Y, Xu J, Bao K, Luo M, Liu X, et al. Epithelial Cells Attenuate Toll-Like Receptor-Mediated Inflammatory Responses in Monocyte-Derived Macrophage-Like Cells to Mycobacterium tuberculosis by Modulating the PI3K/Akt/mTOR Signaling Pathway. Mediators Inflamm. 2018;2018:3685948 pubmed publisher
Huang T, Liu D, Wang Y, Li P, Sun L, Xiong H, et al. FGFR2 Promotes Gastric Cancer Progression by Inhibiting the Expression of Thrombospondin4 via PI3K-Akt-Mtor Pathway. Cell Physiol Biochem. 2018;50:1332-1345 pubmed publisher
Cheng B, Lu J, Li T, Meng Z, Liu M, Sun M, et al. 1,3-Dichloro-2-Propanol inhibits autophagy via P53/AMPK/mTOR pathway in HepG2 cells. Food Chem Toxicol. 2018;122:143-150 pubmed publisher
Yin Y, Zhou L, Zhan R, Zhang Q, Li M. Identification of WDR12 as a novel oncogene involved in hepatocellular carcinoma propagation. Cancer Manag Res. 2018;10:3985-3993 pubmed publisher
Batool S, Joseph T, Hussain M, Vuai M, Khinsar K, Din S, et al. LP1 from Lentinula edodes C91-3 Induces Autophagy, Apoptosis and Reduces Metastasis in Human Gastric Cancer Cell Line SGC-7901. Int J Mol Sci. 2018;19: pubmed publisher
Yao R, Yang Y, Lian S, Shi H, Liu P, Liu Y, et al. Effects of Acute Cold Stress on Liver O-GlcNAcylation and Glycometabolism in Mice. Int J Mol Sci. 2018;19: pubmed publisher
Zou W, Ding F, Niu C, Fu Z, Liu S. Brg1 aggravates airway inflammation in asthma via inhibition of the PI3K/Akt/mTOR pathway. Biochem Biophys Res Commun. 2018;503:3212-3218 pubmed publisher
Guo S, Liang X, Guo M, Zhang X, Li Z. Migration inhibition of water stress proteins from Nostoc commune Vauch. via activation of autophagy in DLD-1 cells. Int J Biol Macromol. 2018;119:669-676 pubmed publisher
Yin J, Li Y, Han H, Liu Z, Zeng X, Li T, et al. Long-term effects of lysine concentration on growth performance, intestinal microbiome, and metabolic profiles in a pig model. Food Funct. 2018;9:4153-4163 pubmed publisher
Jin J, Hu K, Ye M, Wu D, He Q. Rapamycin Reduces Podocyte Apoptosis and is Involved in Autophagy and mTOR/ P70S6K/4EBP1 Signaling. Cell Physiol Biochem. 2018;48:765-772 pubmed publisher
Li Y, Zeng C, Hu J, Pan Y, Shan Y, Liu B, et al. Long non-coding RNA-SNHG7 acts as a target of miR-34a to increase GALNT7 level and regulate PI3K/Akt/mTOR pathway in colorectal cancer progression. J Hematol Oncol. 2018;11:89 pubmed publisher
Wang Y, Gu Y, Liang L, Liu M, Jiang B, Zhu M, et al. Concurrence of autophagy with apoptosis in alveolar epithelial cells contributes to chronic pulmonary toxicity induced by methamphetamine. Cell Prolif. 2018;51:e12476 pubmed publisher
Wu F, Li S, Zhang N, Huang W, Li X, Wang M, et al. Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy. Biomed Pharmacother. 2018;104:307-314 pubmed publisher
Ji J, Xue T, Guo X, Yang J, Guo R, Wang J, et al. Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway. Aging Cell. 2018;17:e12774 pubmed publisher
Li R, Wang L, Du J, Zhao L, Yao Y. Autophagy activation and the mechanism of retinal microvascular endothelial cells in hypoxia. Int J Ophthalmol. 2018;11:567-574 pubmed publisher
Wu Z, Zhu Q, Zhang Y, Yin Y, Kang D, Cao R, et al. EGFR‑associated pathways involved in traditional Chinese medicine (TCM)‑1‑induced cell growth inhibition, autophagy and apoptosis in prostate cancer. Mol Med Rep. 2018;17:7875-7885 pubmed publisher
Yang G, Bai Y, Wu X, Sun X, Sun M, Liu X, et al. Patulin induced ROS-dependent autophagic cell death in Human Hepatoma G2 cells. Chem Biol Interact. 2018;288:24-31 pubmed publisher
Wu Z, Zhu Q, Yin Y, Kang D, Cao R, Tian Q, et al. Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer. Cancer Med. 2018;7:1546-1559 pubmed publisher
Li C, Zhang J, Xu H, Chang M, Lv C, Xue W, et al. Retigabine ameliorates acute stress-induced impairment of spatial memory retrieval through regulating USP2 signaling pathways in hippocampal CA1 area. Neuropharmacology. 2018;135:151-162 pubmed publisher
Huang L, Chen C, Zhang X, Li X, Chen Z, Yang C, et al. Neuroprotective Effect of Curcumin Against Cerebral Ischemia-Reperfusion Via Mediating Autophagy and Inflammation. J Mol Neurosci. 2018;64:129-139 pubmed publisher
Duan J, Du C, Shi Y, Liu D, Ma J. Thioredoxin-interacting protein deficiency ameliorates diabetic retinal angiogenesis. Int J Biochem Cell Biol. 2018;94:61-70 pubmed publisher
Liu C, Xing J, Gao Y. UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis. Thorac Cancer. 2018;9:105-111 pubmed publisher
Li M, Jin C, Xu M, Zhou L, Li D, Yin Y. Bifunctional enzyme ATIC promotes propagation of hepatocellular carcinoma by regulating AMPK-mTOR-S6 K1 signaling. Cell Commun Signal. 2017;15:52 pubmed publisher
Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, et al. Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells. Molecules. 2017;22: pubmed publisher
Guo D, Murdoch C, Xu H, Shi H, DUAN D, Ahmed A, et al. Vascular endothelial growth factor signaling requires glycine to promote angiogenesis. Sci Rep. 2017;7:14749 pubmed publisher
Xue T, Ding X, Ji J, Yan H, Huang J, Guo X, et al. PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats. J Pharmacol Sci. 2017;135:105-113 pubmed publisher
Sun K, Wu D, Chen S, Zhao Y, Zong Z. LncRNA MEG3 inhibit endometrial carcinoma tumorigenesis and progression through PI3K pathway. Apoptosis. 2017;22:1543-1552 pubmed publisher
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J. Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway. Cell Physiol Biochem. 2017;43:1436-1448 pubmed publisher
Yin J, Li Y, Zhu X, Han H, Ren W, Chen S, et al. Effects of Long-Term Protein Restriction on Meat Quality, Muscle Amino Acids, and Amino Acid Transporters in Pigs. J Agric Food Chem. 2017;65:9297-9304 pubmed publisher
Zhao Z, Zhang L, Guo X, Cao L, Xue T, Zhao X, et al. Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. Front Mol Neurosci. 2017;10:293 pubmed publisher
Liang J, Gao W, Cai L. Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells. Onco Targets Ther. 2017;10:3971-3978 pubmed publisher
Du C, Zhang T, Xiao X, Shi Y, Duan H, Ren Y. Protease-activated receptor-2 promotes kidney tubular epithelial inflammation by inhibiting autophagy via the PI3K/Akt/mTOR signalling pathway. Biochem J. 2017;474:2733-2747 pubmed publisher
Xu L, Yin L, Tao X, Qi Y, Han X, Xu Y, et al. Dioscin, a potent ITGA5 inhibitor, reduces the synthesis of collagen against liver fibrosis: Insights from SILAC-based proteomics analysis. Food Chem Toxicol. 2017;107:318-328 pubmed publisher
Yu Y, Feng L, Li J, Lan X, A L, Lv X, et al. The alteration of autophagy and apoptosis in the hippocampus of rats with natural aging-dependent cognitive deficits. Behav Brain Res. 2017;334:155-162 pubmed publisher
Ke Z, Wang G, Yang L, Qiu H, Wu H, Du M, et al. Crude terpene glycoside component from Radix paeoniae rubra protects against isoproterenol-induced myocardial ischemic injury via activation of the PI3K/AKT/mTOR signaling pathway. J Ethnopharmacol. 2017;206:160-169 pubmed publisher
Zhou W, Liu L, Xue Y, Zheng J, Liu X, Ma J, et al. Combination of Endothelial-Monocyte-Activating Polypeptide-II with Temozolomide Suppress Malignant Biological Behaviors of Human Glioblastoma Stem Cells via miR-590-3p/MACC1 Inhibiting PI3K/AKT/mTOR Signal Pathway. Front Mol Neurosci. 2017;10:68 pubmed publisher
Zhang Z, Guo R, Lv J, Wang X, Ye J, Lu N, et al. MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin. Biochem Biophys Res Commun. 2017;486:414-422 pubmed publisher
Cui X, Long C, Zhu J, Tian J. Protective Effects of Fluvastatin on Reproductive Function in Obese Male Rats Induced by High-Fat Diet through Enhanced Signaling of mTOR. Cell Physiol Biochem. 2017;41:598-608 pubmed publisher
Zhang C, Li C, Chen S, Li Z, Ma L, Jia X, et al. Hormetic effect of panaxatriol saponins confers neuroprotection in PC12 cells and zebrafish through PI3K/AKT/mTOR and AMPK/SIRT1/FOXO3 pathways. Sci Rep. 2017;7:41082 pubmed publisher
Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, et al. Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Oncotarget. 2017;8:8622-8632 pubmed publisher
Shen C, Wei W, Qiu Z, Song H, Zhang X, Sun Z, et al. Metformin reduces glycometabolism of papillary thyroid carcinoma in vitro and in vivo. J Mol Endocrinol. 2017;58:15-23 pubmed
Cao N, Ma X, Guo Z, Zheng Y, Geng S, Meng M, et al. Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity. Oncotarget. 2016;7:61093-61106 pubmed publisher
Du C, Wu M, Liu H, Ren Y, Du Y, Wu H, et al. Thioredoxin-interacting protein regulates lipid metabolism via Akt/mTOR pathway in diabetic kidney disease. Int J Biochem Cell Biol. 2016;79:1-13 pubmed publisher
Dai B, Wang W, Ma Y, Liu R, Zhang Y. A taspine derivative supresses Caco-2 cell growth by competitively targeting EphrinB2 and regulating its pathway. Oncol Rep. 2016;36:1526-34 pubmed publisher
Wang S, Lu J, You Q, Huang H, Chen Y, Liu K. The mTOR/AP-1/VEGF signaling pathway regulates vascular endothelial cell growth. Oncotarget. 2016;7:53269-53276 pubmed publisher
Huang C, Lei K, Tsang N. Paper-based microreactor array for rapid screening of cell signaling cascades. Lab Chip. 2016;16:2911-20 pubmed publisher
Du Q, Hao C, Gou J, Li X, Zou K, He X, et al. Protective effects of p-nitro caffeic acid phenethyl ester on acute myocardial ischemia-reperfusion injury in rats. Exp Ther Med. 2016;11:1433-1440 pubmed
Su C, Niu P. Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways. Int J Clin Exp Med. 2015;8:20508-15 pubmed
Zhan Y, Liu R, Wang W, Li J, Yang X, Zhang Y. Total saponins isolated from Radix et Rhizoma Leonticis suppresses tumor cells growth by regulation of PI3K/Akt/mTOR and p38 MAPK pathways. Environ Toxicol Pharmacol. 2016;41:39-44 pubmed publisher
Wang L, Wang C, Jia Y, Liu Z, Shu X, Liu K. Resveratrol Increases Anti-Proliferative Activity of Bestatin Through Downregulating P-Glycoprotein Expression Via Inhibiting PI3K/Akt/mTOR Pathway in K562/ADR Cells. J Cell Biochem. 2016;117:1233-9 pubmed publisher
Zhang Q, Zhuang J, Deng Y, Zhao X, Tang B, Yao D, et al. GOLPH3 is a potential therapeutic target and a prognostic indicator of poor survival in bladder cancer treated by cystectomy. Oncotarget. 2015;6:32177-92 pubmed publisher
Tan L, Wei X, Zheng L, Zeng J, Liu H, Yang S, et al. Amplified HMGA2 promotes cell growth by regulating Akt pathway in AML. J Cancer Res Clin Oncol. 2016;142:389-99 pubmed publisher
Li X, Zou K, Gou J, Du Q, Li D, He X, et al. Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells. Med Oncol. 2015;32:72 pubmed publisher
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, et al. Potent effects of dioscin against obesity in mice. Sci Rep. 2015;5:7973 pubmed publisher
product information
CatalogNo :
20657-1-AP
AntigenName :
mTOR
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
FK506 binding protein 12-rapamycin associated protein 1
Immunogen :
Peptide
Species :
chicken, cow, hamster, human, medaka, mouse, pig, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, MTOR, RAFT1, Rapamycin target protein 1, RAPT1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_004958
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:500 ; WB 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.