This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
DDX58
catalog :
20566-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 14
Published Application/Species/Sample/DilutionReference
  • immunoprecipitation; mouse; 1:2000; loading ...; fig 4c, 4i, 5f
  • western blot; mouse; 1:2000; loading ...; fig 4a, 4c, 4i, 5f
  • immunoprecipitation; human; 1:2000; loading ...; fig s5d
Liu Z, Wu C, Pan Y, Liu H, Wang X, Yang Y, et al. NDR2 promotes the antiviral immune response via facilitating TRIM25-mediated RIG-I activation in macrophages. Sci Adv. 2019;5:eaav0163 pubmed publisher
  • western blot; mouse; 1:2000; loading ...; fig s4a
Liu Z, Qin Q, Wu C, Li H, Shou J, Yang Y, et al. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop. Nat Commun. 2018;9:2789 pubmed publisher
  • western blot; human; 1:2000; fig 3
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
Wang C, Li Y, Yan S, Wang H, Shao X, Xiao M, et al. Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2. Nat Commun. 2020;11:3162 pubmed publisher
Chemudupati M, Kenney A, Smith A, Fillinger R, Zhang L, Zani A, et al. Butyrate Reprograms Expression of Specific Interferon-Stimulated Genes. J Virol. 2020;94: pubmed publisher
Zhou Z, Ni J, Li J, Huo C, Miao N, Yin F, et al. RIG-I aggravates interstitial fibrosis via c-Myc-mediated fibroblast activation in UUO mice. J Mol Med (Berl). 2020;98:527-540 pubmed publisher
Bianco C, Mohr I. Ribosome biogenesis restricts innate immune responses to virus infection and DNA. elife. 2019;8: pubmed publisher
Wang K, Ma H, Liu H, Ye W, Li Z, Cheng L, et al. The Glycoprotein and Nucleocapsid Protein of Hantaviruses Manipulate Autophagy Flux to Restrain Host Innate Immune Responses. Cell Rep. 2019;27:2075-2091.e5 pubmed publisher
Ringeard M, Marchand V, Decroly E, Motorin Y, Bennasser Y. FTSJ3 is an RNA 2'-O-methyltransferase recruited by HIV to avoid innate immune sensing. Nature. 2019;565:500-504 pubmed publisher
Zhang L, Wang J, Muñoz Moreno R, Kim M, Sakthivel R, Mo W, et al. Influenza Virus NS1 Protein-RNA Interactome Reveals Intron Targeting. J Virol. 2018;92: pubmed publisher
Burgess H, Mohr I. Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS. J Virol. 2018;92: pubmed publisher
Zhang L, Xin Q, Zhu S, Wan W, Wang W, Xiao G. Activation of the RLR/MAVS Signaling Pathway by the L Protein of Mopeia Virus. J Virol. 2016;90:10259-10270 pubmed publisher
Wang Y, Liu L. The Membrane Protein of Severe Acute Respiratory Syndrome Coronavirus Functions as a Novel Cytosolic Pathogen-Associated Molecular Pattern To Promote Beta Interferon Induction via a Toll-Like-Receptor-Related TRAF3-Independent Mechanism. MBio. 2016;7:e01872-15 pubmed publisher
Zhang W, Zhang L, Zan Y, Du N, Yang Y, Tien P. Human respiratory syncytial virus infection is inhibited by IFN-induced transmembrane proteins. J Gen Virol. 2015;96:170-82 pubmed publisher
product information
CatalogNo :
20566-1-AP
AntigenName :
DDX58
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
Immunogen :
Peptide
Species :
human, mouse
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
DDX58, DEAD box protein 58, RIG 1, RIG I, RIG-I
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_014314
Category :
Apoptosis;Binding Proteins;Immunology;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IP 1:300 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.