This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
DMT1
catalog :
20507-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:200; fig 1
Geng J, Li J, Huang T, Zhao K, Chen Q, Guo W, et al. A novel manganese complex selectively induces malignant glioma cell death by targeting mitochondria. Mol Med Rep. 2016;14:1970-8 pubmed publisher
Morgan S, Schroten H, Ishikawa H, Zhao N. Localization of ZIP14 and ZIP8 in HIBCPP Cells. Brain Sci. 2020;10: pubmed publisher
Li S, Qian Z, Xu G, Zheng J, Wu Y. Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron. Biosci Rep. 2020;40: pubmed publisher
Weber R, Yen F, Nicholson S, Alwaseem H, Bayraktar E, Alam M, et al. Maintaining Iron Homeostasis Is the Key Role of Lysosomal Acidity for Cell Proliferation. Mol Cell. 2020;77:645-655.e7 pubmed publisher
Song Q, Zhao Y, Li Q, Han X, Duan J. Puerarin protects against iron overload-induced retinal injury through regulation of iron-handling proteins. Biomed Pharmacother. 2020;122:109690 pubmed publisher
Zhao P, Qian C, Chen Y, Sheng Y, Ke Y, Qian Z. Cystathionine β-synthase (CBS) deficiency suppresses erythropoiesis by disrupting expression of heme biosynthetic enzymes and transporter. Cell Death Dis. 2019;10:708 pubmed publisher
Hu P, Zhao D, Zhao F, Wang J, Zhu W. The Effects of the Combination of Oral Lactoferrin and Iron Injection on Iron Homestasis, Antioxidative Abilities and Cytokines Activities of Suckling Piglets. Animals (Basel). 2019;9: pubmed publisher
Scheiber I, Wu Y, Morgan S, Zhao N. The intestinal metal transporter ZIP14 maintains systemic manganese homeostasis. J Biol Chem. 2019;294:9147-9160 pubmed publisher
Zhang M, Zhao P, Yung W, Sheng Y, Ke Y, Qian Z. Tissue iron is negatively correlated with TERC or TERT mRNA expression: A heterochronic parabiosis study in mice. Aging (Albany NY). 2018;10:3834-3850 pubmed publisher
Yang L, Wang D, Wang X, Lu Y, Zhu L. The roles of hypoxia-inducible Factor-1 and iron regulatory protein 1 in iron uptake induced by acute hypoxia. Biochem Biophys Res Commun. 2018;507:128-135 pubmed publisher
Liu C, Zhang C, Lo S, Ang S, Chew K, Yu D, et al. S-Nitrosylation of Divalent Metal Transporter 1 Enhances Iron Uptake to Mediate Loss of Dopaminergic Neurons and Motoric Deficit. J Neurosci. 2018;38:8364-8377 pubmed publisher
Zhao N, Zhang A, Wortham A, Jue S, Knutson M, Enns C. The Tumor Suppressor, P53, Decreases the Metal Transporter, ZIP14. Nutrients. 2017;9: pubmed publisher
Zhou Y, Zhang C, Yang G, Qian Z, Zhang M, Ma J, et al. Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron. Front Physiol. 2017;8:332 pubmed publisher
product information
CatalogNo :
20507-1-AP
AntigenName :
DMT1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
Immunogen :
Fusion Protein
Species :
human, mouse, piglet, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
DCT1, Divalent cation transporter 1, Divalent metal transporter 1, DMT 1, DMT1, NRAMP 2, NRAMP2, SLC11A2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC002592
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Membrane Proteins;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.