This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IGF1R beta chain
catalog :
20254-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 20
Reference
Wang H, Wang F, Ouyang W, Jiang X, Li W. MALAT1 knockdown inhibits hypopharyngeal squamous cell carcinoma malignancy by targeting microRNA-194. Oncol Lett. 2020;20:173-182 pubmed publisher
Zhao Z, Zhang N, Li A, Zhou B, Chen Y, Chen S, et al. Insulin-like growth factor-1 receptor induces immunosuppression in lung cancer by upregulating B7-H4 expression through the MEK/ERK signaling pathway. Cancer Lett. 2020;485:14-26 pubmed publisher
Wang K, Huang R, Wu C, Li G, Zhao Z, Hu H, et al. Receptor tyrosine kinase expression in high-grade gliomas before and after chemoradiotherapy. Oncol Lett. 2019;18:6509-6515 pubmed publisher
Xiao M, Guo J, Xie L, Yang C, Gong L, Wang Z, et al. Let-7e suppresses DNA damage repair and sensitizes ovarian cancer to cisplatin through targeting PARP1. Mol Cancer Res. 2019;: pubmed publisher
Wang S, Wang N, Yu B, Cao M, Wang Y, Guo Y, et al. Circulating IGF-1 promotes prostate adenocarcinoma via FOXO3A/BIM signaling in a double-transgenic mouse model. Oncogene. 2019;38:6338-6353 pubmed publisher
Shao P, Wang Y, Zhang M, Wen X, Zhang J, Xu Z, et al. The interference of DEHP in precocious puberty of females mediated by the hypothalamic IGF-1/PI3K/Akt/mTOR signaling pathway. Ecotoxicol Environ Saf. 2019;181:362-369 pubmed publisher
Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, et al. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids Surf B Biointerfaces. 2019;179:66-76 pubmed publisher
Lai G, Li X, Zhang B, Wang L, He R, Zhao Y. Decreased Amino Acid Concentrations are Involved in Congenital Heart Disease. Ann Nutr Metab. 2019;74:257-263 pubmed publisher
Liu E, Zhou Q, Xie A, Li M, Zhang S, Huang H, et al. Enriched gestation activates the IGF pathway to evoke embryo-adult benefits to prevent Alzheimer's disease. Transl Neurodegener. 2019;8:8 pubmed publisher
Ma W, Feng W, Tan J, Xu A, Hu Y, Ning L, et al. miR-497 may enhance the sensitivity of non-small cell lung cancer cells to gefitinib through targeting the insulin-like growth factor-1 receptor. J Thorac Dis. 2018;10:5889-5897 pubmed publisher
Zhang Y, Sun Y, Peng R, Liu H, He W, Zhang L, et al. The Long Noncoding RNA 150Rik Promotes Mesangial Cell Proliferation via miR-451/IGF1R/p38 MAPK Signaling in Diabetic Nephropathy. Cell Physiol Biochem. 2018;51:1410-1428 pubmed publisher
Li Z, Lu Q, Zhu D, Han Y, Zhou X, Ren T. Lnc-SNHG1 may promote the progression of non-small cell lung cancer by acting as a sponge of miR-497. Biochem Biophys Res Commun. 2018;506:632-640 pubmed publisher
Zhao X, Yang S, Yan Y, Zhang X, Zhang L, Jiao B, et al. Identification of differential gene expression profile from peripheral blood cells of military pilots with hypertension by RNA sequencing analysis. BMC Med Genomics. 2018;11:59 pubmed publisher
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R. Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams. J Agric Food Chem. 2018;66:2704-2713 pubmed publisher
Zheng S, Wan W, Miao H, Tang R, Wang B, Huang Q, et al. Leptocarpin Suppresses Proliferation, Migration, and Invasion of Human Osteosarcoma by Targeting Type-1 Insulin-Like Growth Factor Receptor (IGF-1R). Med Sci Monit. 2017;23:4132-4140 pubmed
Zhuang S, Jian Y, Sun Y. Inhibition of N-methyl-N-nitrosourea-induced gastric tumorigenesis by Liuwei Dihuang Pill in db/db mice. World J Gastroenterol. 2017;23:4233-4242 pubmed publisher
Jin H, Wang C, Jin G, Ruan H, Gu D, Wei L, et al. Regulator of Calcineurin 1 Gene Isoform 4, Down-regulated in Hepatocellular Carcinoma, Prevents Proliferation, Migration, and Invasive Activity of Cancer Cells and Metastasis of Orthotopic Tumors by Inhibiting Nuclear Translocation of NFAT1. Gastroenterology. 2017;153:799-811.e33 pubmed publisher
Li Z, Xiong Q, Xu L, Duan P, Yang Q, Zhou P, et al. miR-29a regulated ER-positive breast cancer cell growth and invasion and is involved in the insulin signaling pathway. Oncotarget. 2017;8:32566-32575 pubmed publisher
Zhang Z, Guo R, Lv J, Wang X, Ye J, Lu N, et al. MicroRNA-99a inhibits insulin-induced proliferation, migration, dedifferentiation, and rapamycin resistance of vascular smooth muscle cells by inhibiting insulin-like growth factor-1 receptor and mammalian target of rapamycin. Biochem Biophys Res Commun. 2017;486:414-422 pubmed publisher
Xu S, Zhang B, Zhu Y, Huang H, Yang W, Huang H, et al. miR-194 functions as a novel modulator of cellular senescence in mouse embryonic fibroblasts. Cell Biol Int. 2017;41:249-257 pubmed publisher
product information
CatalogNo :
20254-1-AP
AntigenName :
IGF1R beta chain
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
IGF I receptor
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CD221, IGF I receptor, IGF1R, IGFIR, IGFR, JTK13
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000875
Category :
Apoptosis;Binding Proteins;Cell Cycle;Development;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; IP 1:300 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.