This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TFAM
catalog :
19998-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, zebrafish
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 22
Published Application/Species/Sample/DilutionReference
  • western blot; zebrafish ; loading ...; fig 5c
Chen D, Zhang Z, Chen C, Yao S, Yang Q, Li F, et al. Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism. Nucleic Acids Res. 2019;47:5341-5355 pubmed publisher
Wu H, Wei H, Zhang D, Sehgal S, Zhang D, Wang X, et al. Defective mitochondrial ISCs biogenesis switches on IRP1 to fine tune selective mitophagy. Redox Biol. 2020;36:101661 pubmed publisher
Wang J, Li S, Wang J, Wu F, Chen Y, Zhang H, et al. Spermidine alleviates cardiac aging by improving mitochondrial biogenesis and function. Aging (Albany NY). 2020;12:650-671 pubmed publisher
Kang Y, Li Y, Zhang T, Chi Y, Liu M. Effects of transcription factor EB on oxidative stress and apoptosis induced by high glucose in podocytes. Int J Mol Med. 2019;44:447-456 pubmed publisher
Zhang T, Chi Y, Ren Y, Du C, Shi Y, Li Y. Resveratrol Reduces Oxidative Stress and Apoptosis in Podocytes via Sir2-Related Enzymes, Sirtuins1 (SIRT1)/Peroxisome Proliferator-Activated Receptor γ Co-Activator 1α (PGC-1α) Axis. Med Sci Monit. 2019;25:1220-1231 pubmed publisher
Lei P, Tian S, Teng C, Huang L, Liu X, Wang J, et al. Sulforaphane Improves Lipid Metabolism by Enhancing Mitochondrial Function and Biogenesis In Vivo and In Vitro. Mol Nutr Food Res. 2019;63:e1800795 pubmed publisher
Deng X, Liu J, Sun X, Dong J, Huang J. Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade. Acta Pharmacol Sin. 2019;40:658-665 pubmed publisher
Zhang T, Chi Y, Kang Y, Lu H, Niu H, Liu W, et al. Resveratrol ameliorates podocyte damage in diabetic mice via SIRT1/PGC-1α mediated attenuation of mitochondrial oxidative stress. J Cell Physiol. 2019;234:5033-5043 pubmed publisher
Kou G, Li Z, Wu C, Liu Y, Hu Y, Guo L, et al. Citrus Tangeretin Improves Skeletal Muscle Mitochondrial Biogenesis via Activating the AMPK-PGC1-α Pathway In Vitro and In Vivo: A Possible Mechanism for Its Beneficial Effect on Physical Performance. J Agric Food Chem. 2018;66:11917-11925 pubmed publisher
Ruzzenente B, Assouline Z, Barcia G, Rio M, Boddaert N, Munnich A, et al. Inhibition of mitochondrial translation in fibroblasts from a patient expressing the KARS p.(Pro228Leu) variant and presenting with sensorineural deafness, developmental delay, and lactic acidosis. Hum Mutat. 2018;39:2047-2059 pubmed publisher
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, et al. Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology. Cell Rep. 2018;23:2989-3005 pubmed publisher
Foote K, Reinhold J, Yu E, Figg N, Finigan A, Murphy M, et al. Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice. Aging Cell. 2018;17:e12773 pubmed publisher
Yin J, Guo J, Zhang Q, Cui L, Zhang L, Zhang T, et al. Doxorubicin-induced mitophagy and mitochondrial damage is associated with dysregulation of the PINK1/parkin pathway. Toxicol In Vitro. 2018;51:1-10 pubmed publisher
Liu J, Lee I, Feng H, Galen S, Hüttemann P, Perkins G, et al. Aerobic Exercise Preconception and During Pregnancy Enhances Oxidative Capacity in the Hindlimb Muscles of Mice Offspring. J Strength Cond Res. 2018;32:1391-1403 pubmed publisher
Kim J, Ha J, Yang S, Son J. A Novel Non-Apoptotic Role of Procaspase-3 in the Regulation of Mitochondrial Biogenesis Activators. J Cell Biochem. 2018;119:347-357 pubmed publisher
Cui L, Guo J, Zhang Q, Yin J, Li J, Zhou W, et al. Erythropoietin activates SIRT1 to protect human cardiomyocytes against doxorubicin-induced mitochondrial dysfunction and toxicity. Toxicol Lett. 2017;275:28-38 pubmed publisher
Hill S, Deepa S, Sataranatarajan K, Premkumar P, Pulliam D, Liu Y, et al. Sco2 deficient mice develop increased adiposity and insulin resistance. Mol Cell Endocrinol. 2017;455:103-114 pubmed publisher
Zhao X, Sun K, Lan Z, Song W, Cheng L, Chi W, et al. Tenofovir and adefovir down-regulate mitochondrial chaperone TRAP1 and succinate dehydrogenase subunit B to metabolically reprogram glucose metabolism and induce nephrotoxicity. Sci Rep. 2017;7:46344 pubmed publisher
Gao W, Wu M, Wang N, Ying M, Zhang Y, Hua J, et al. Mitochondrial transcription factor A contributes to cisplatin resistance in patients with estrogen receptor?positive breast cancer. Mol Med Rep. 2016;14:5304-5310 pubmed publisher
Zhang T, Zhang Q, Guo J, Yuan H, Peng H, Cui L, et al. Non-cytotoxic concentrations of acetaminophen induced mitochondrial biogenesis and antioxidant response in HepG2 cells. Environ Toxicol Pharmacol. 2016;46:71-79 pubmed publisher
Geng J, Sun X, Wang P, Zhang S, Wang X, Wu H, et al. Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity. Nat Immunol. 2015;16:1142-52 pubmed publisher
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, et al. Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ. 2016;23:380-92 pubmed publisher
product information
CatalogNo :
19998-1-AP
AntigenName :
TFAM
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
transcription factor A, mitochondrial
Immunogen :
Peptide
Species :
human, mouse, rat, zebrafish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
MtTF1, mtTFA, TCF 6, TCF6, TCF6L1, TCF6L2, TCF6L3, TFAM, Transcription factor 6, Transcription factor 6 like 2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_003201
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.