This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CYP2E1-Specific
catalog :
19937-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 30
Reference
Zheng D, Jiang Y, Qu C, Yuan H, Hu K, He L, et al. Pyruvate kinase M2 (PKM2) tetramerization protects against hepatic stellate cell activation and liver fibrosis. Am J Pathol. 2020;: pubmed publisher
Yamada N, Karasawa T, Kimura H, Watanabe S, Komada T, Kamata R, et al. Ferroptosis driven by radical oxidation of n-6 polyunsaturated fatty acids mediates acetaminophen-induced acute liver failure. Cell Death Dis. 2020;11:144 pubmed publisher
Zhao L, Zhao J, Gao R, Tian Y, Zhang Y, Tang W, et al. Intrabody against prolyl hydroxylase 2 ameliorates acetaminophen-induced acute liver injury in mice via concomitant promotion of angiogenesis and redox homeostasis. Biomed Pharmacother. 2020;123:109783 pubmed publisher
Peng C, Zhou Z, Li J, Luo Y, Zhou Y, Ke X, et al. CCl4-Induced Liver Injury Was Ameliorated by Qi-Ge Decoction through the Antioxidant Pathway. Evid Based Complement Alternat Med. 2019;2019:5941263 pubmed publisher
Zhou X, Xiong J, Lu S, Luo L, Chen Z, Yang F, et al. Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway. Am J Chin Med. 2019;47:1541-1569 pubmed publisher
Yuan J, Chen C, Cui J, Lu J, Yan C, Wei X, et al. Fatty Liver Disease Caused by High-Alcohol-Producing Klebsiella pneumoniae. Cell Metab. 2019;30:675-688.e7 pubmed publisher
Yamasaki K, Sugamoto K, Arakawa T, Nishiyama K, Yamasaki M. Chronic intake of high-dose of blueberry leaf extract does not augment the harmful effects of ethanol in rats. Peerj. 2019;7:e6989 pubmed publisher
Hua H, Zhang Z, Qian Y, Yuan H, Ge W, Huang S, et al. Inhibition of the mitochondrial complex-1 protects against carbon tetrachloride-induced acute liver injury. Biomed Pharmacother. 2019;115:108948 pubmed publisher
Wu C, Liu J, Tang Y, Li Y, Yan Q, Jiang Z. Hepatoprotective Potential of Partially Hydrolyzed Guar Gum against Acute Alcohol-Induced Liver Injury in Vitro and Vivo. Nutrients. 2019;11: pubmed publisher
Qi Y, Li R, Xu L, Yin L, Xu Y, Han X, et al. Neuroprotective Effect of Dioscin on the Aging Brain. Molecules. 2019;24: pubmed publisher
Qu L, Zhu Y, Liu Y, Yang H, Zhu C, Ma P, et al. Protective effects of ginsenoside Rk3 against chronic alcohol-induced liver injury in mice through inhibition of inflammation, oxidative stress, and apoptosis. Food Chem Toxicol. 2019;126:277-284 pubmed publisher
Chen L, Guo P, Zhang H, Li W, Gao C, Huang Z, et al. Benzene-induced mouse hematotoxicity is regulated by a protein phosphatase 2A complex that stimulates transcription of cytochrome P4502E1. J Biol Chem. 2019;294:2486-2499 pubmed publisher
Bai D, Li Q, Wang J, Zhao J, Deng X, Yuan L, et al. Neurotoxicity, behavioral changes and gene-expression profile of mice exposed to SnS2 nanoflowers. Toxicol Res (Camb). 2018;7:1267-1279 pubmed publisher
Wang C, Xu W, Zhang Y, Huang D, Huang K. Poly(ADP-ribosyl)ated PXR is a critical regulator of acetaminophen-induced hepatotoxicity. Cell Death Dis. 2018;9:819 pubmed publisher
Ning C, Gao X, Wang C, Kong Y, Liu Z, Sun H, et al. Ginsenoside Rg1 protects against acetaminophen-induced liver injury via activating Nrf2 signaling pathway in vivo and in vitro. Regul Toxicol Pharmacol. 2018;98:58-68 pubmed publisher
Li B, Li D, Wang Y, Meng X, Sun X, Tian J, et al. Schisantherin A alleviated alcohol-induced liver injury by the regulation of alcohol metabolism and NF-kB pathway. Exp Anim. 2018;67:451-461 pubmed publisher
Shi X, Zhao Y, Ding C, Wang Z, Ji A, Li Z, et al. Salvianolic acid A alleviates chronic ethanol-induced liver injury via promotion of β-catenin nuclear accumulation by restoring SIRT1 in rats. Toxicol Appl Pharmacol. 2018;350:21-31 pubmed publisher
Zhang X, Zeng Y, Chen X, Zhang Y, Ding J, Xue C. Decreased expression of hepatic cytochrome P450 1A2 (CYP1A2) in a chronic intermittent hypoxia mouse model. J Thorac Dis. 2018;10:825-834 pubmed publisher
Wang F, Liu J, Zhou R, Zhao X, Liu M, Ye H, et al. Apigenin protects against alcohol-induced liver injury in mice by regulating hepatic CYP2E1-mediated oxidative stress and PPAR?-mediated lipogenic gene expression. Chem Biol Interact. 2017;275:171-177 pubmed publisher
Yang G, Zhang L, Ma L, Jiang R, Kuang G, Li K, et al. Glycyrrhetinic acid prevents acetaminophen-induced acute liver injury via the inhibition of CYP2E1 expression and HMGB1-TLR4 signal activation in mice. Int Immunopharmacol. 2017;50:186-193 pubmed publisher
Wu H, Zhang G, Huang L, Pang H, Zhang N, Chen Y, et al. Hepatoprotective Effect of Polyphenol-Enriched Fraction from Folium Microcos on Oxidative Stress and Apoptosis in Acetaminophen-Induced Liver Injury in Mice. Oxid Med Cell Longev. 2017;2017:3631565 pubmed publisher
Wang H, Xu Y, Wang M, Cheng C, Bian R, Yuan H, et al. Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders. Int J Mol Med. 2017;39:819-830 pubmed publisher
Jiang W, Guo M, Hai X. Hepatoprotective and antioxidant effects of lycopene on non-alcoholic fatty liver disease in rat. World J Gastroenterol. 2016;22:10180-10188 pubmed publisher
Katen A, Chambers C, Nixon B, Roman S. Chronic Acrylamide Exposure in Male Mice Results in Elevated DNA Damage in the Germline and Heritable Induction of CYP2E1 in the Testes. Biol Reprod. 2016;95:86 pubmed publisher
Ren Z, Yang F, Wang X, Wang Y, Xu M, Frank J, et al. Chronic plus binge ethanol exposure causes more severe pancreatic injury and inflammation. Toxicol Appl Pharmacol. 2016;308:11-19 pubmed publisher
Shi H, Shi A, Dong L, Lu X, Wang Y, Zhao J, et al. Chlorogenic acid protects against liver fibrosis in vivo and in vitro through inhibition of oxidative stress. Clin Nutr. 2016;35:1366-1373 pubmed publisher
Dong D, Yin L, Qi Y, Xu L, Peng J. Protective Effect of the Total Saponins from Rosa laevigata Michx Fruit against Carbon Tetrachloride-Induced Liver Fibrosis in Rats. Nutrients. 2015;7:4829-50 pubmed publisher
Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher
Zhang B, Liu Y, Li X. Alteration in the expression of cytochrome P450s (CYP1A1, CYP2E1, and CYP3A11) in the liver of mouse induced by microcystin-LR. Toxins (Basel). 2015;7:1102-15 pubmed publisher
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, et al. Potent effects of dioscin against obesity in mice. Sci Rep. 2015;5:7973 pubmed publisher
product information
CatalogNo :
19937-1-AP
AntigenName :
CYP2E1-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
cytochrome P450, family 2, subfamily E, polypeptide 1
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
4 nitrophenol 2 hydroxylase, CPE1, CYP2E, CYP2E1, CYP-2E1, CYPIIE1, Cytochrome P450 2E1, Cytochrome P450 J, P450 J, P450C2E
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000773
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:200 ; WB 1:6000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.