TMEM173/STING | Proteintech Group 19851-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

TMEM173/STING

catalog :

19851-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, western blot knockout validation

citations: 32

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; mouse; 1:1000; fig 3 western blot; human; 1:1000; fig 3	Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed publisher
immunocytochemistry; human; 1:500; loading ...; fig 6d	Xing J, Zhang A, Zhang H, Wang J, Li X, Zeng M, et al. TRIM29 promotes DNA virus infections by inhibiting innate immune response. Nat Commun. 2017;8:945 pubmed publisher
western blot; human; loading ...; fig 1c	Liu Y, Qu L, Liu Y, Roizman B, Zhou G. PUM1 is a biphasic negative regulator of innate immunity genes by suppressing LGP2. Proc Natl Acad Sci U S A. 2017;114:E6902-E6911 pubmed publisher
	Li W, Luo Z, Yan C, Wang X, He Z, Ouyang S, et al. Autophagic degradation of PML promotes susceptibility to HSV-1 by stress-induced corticosterone. Theranostics. 2020;10:9032-9049 pubmed publisher
	Zhang C, Huang D, Baloche V, Zhang L, Xu J, Li B, et al. Galectin-9 promotes a suppressive microenvironment in human cancer by enhancing STING degradation. Oncogenesis. 2020;9:65 pubmed publisher
	Peng Y, Zhuang J, Ying G, Zeng H, Zhou H, Cao Y, et al. Stimulator of IFN genes mediates neuroinflammatory injury by suppressing AMPK signal in experimental subarachnoid hemorrhage. J Neuroinflammation. 2020;17:165 pubmed publisher
	Yang B, Liu Y, Cui Y, Song D, Zhang G, Ma S, et al. RNF90 negatively regulates cellular antiviral responses by targeting MITA for degradation. PLoS Pathog. 2020;16:e1008387 pubmed publisher
	Nozawa T, Sano S, Minowa Nozawa A, Toh H, Nakajima S, Murase K, et al. TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy. Nat Commun. 2020;11:770 pubmed publisher
	Pokatayev V, Yang K, Tu X, Dobbs N, Wu J, Kalb R, et al. Homeostatic regulation of STING protein at the resting state by stabilizer TOLLIP. Nat Immunol. 2020;21:158-167 pubmed publisher
	Hu S, Sun H, Yin L, Li J, Mei S, Xu F, et al. PKR-dependent cytosolic cGAS foci are necessary for intracellular DNA sensing. Sci Signal. 2019;12: pubmed publisher
	Abdel Nour M, Carneiro L, Downey J, Tsalikis J, Outlioua A, Prescott D, et al. The heme-regulated inhibitor is a cytosolic sensor of protein misfolding that controls innate immune signaling. Science. 2019;365: pubmed publisher
	Li L, Yang L, Cheng S, Fan Z, Shen Z, Xue W, et al. Lung adenocarcinoma-intrinsic GBE1 signaling inhibits anti-tumor immunity. Mol Cancer. 2019;18:108 pubmed publisher
	Ye L, Zhang Q, Liuyu T, Xu Z, Zhang M, Luo M, et al. USP49 negatively regulates cellular antiviral responses via deconjugating K63-linked ubiquitination of MITA. PLoS Pathog. 2019;15:e1007680 pubmed publisher
	Chen W, Yu S, Zhou F, Zhang X, Gao W, Li K, et al. DNA Sensor IFI204 Contributes to Host Defense Against Staphylococcus aureus Infection in Mice. Front Immunol. 2019;10:474 pubmed publisher
	García Belmonte R, Pérez Núñez D, Pittau M, Richt J, Revilla Y. African Swine Fever Virus Armenia/07 Virulent Strain Controls Interferon Beta Production through the cGAS-STING Pathway. J Virol. 2019;93: pubmed publisher
	Gui X, Yang H, Li T, Tan X, Shi P, Li M, et al. Autophagy induction via STING trafficking is a primordial function of the cGAS pathway. Nature. 2019;567:262-266 pubmed publisher
	Zhang C, Ye S, Ni J, Cai T, Liu Y, Huang D, et al. STING signaling remodels the tumor microenvironment by antagonizing myeloid-derived suppressor cell expansion. Cell Death Differ. 2019;: pubmed publisher
	Li Q, Liu C, Yue R, El Ashram S, Wang J, He X, et al. cGAS/STING/TBK1/IRF3 Signaling Pathway Activates BMDCs Maturation Following Mycobacterium bovis Infection. Int J Mol Sci. 2019;20: pubmed publisher
	Torralba D, Baixauli F, Villarroya Beltri C, Fernandez Delgado I, Latorre Pellicer A, Acin Perez R, et al. Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts. Nat Commun. 2018;9:2658 pubmed publisher
	Burgess H, Mohr I. Defining the Role of Stress Granules in Innate Immune Suppression by the Herpes Simplex Virus 1 Endoribonuclease VHS. J Virol. 2018;92: pubmed publisher
	Yang B, Song D, Liu Y, Cui Y, Lu G, Di W, et al. IFI16 regulates HTLV-1 replication through promoting HTLV-1 RTI-induced innate immune responses. FEBS Lett. 2018;592:1693-1704 pubmed publisher
	Verrier E, Yim S, Heydmann L, El Saghire H, Bach C, Turon Lagot V, et al. Hepatitis B Virus Evasion From Cyclic Guanosine Monophosphate-Adenosine Monophosphate Synthase Sensing in Human Hepatocytes. Hepatology. 2018;68:1695-1709 pubmed publisher
	Wang Y, Song L, Liu M, Ge R, Zhou Q, Liu W, et al. A proteomics landscape of circadian clock in mouse liver. Nat Commun. 2018;9:1553 pubmed publisher
	Motani K, Kosako H. Activation of stimulator of interferon genes (STING) induces ADAM17-mediated shedding of the immune semaphorin SEMA4D. J Biol Chem. 2018;293:7717-7726 pubmed publisher
	Liu Y, Liu Y, Wu J, Roizman B, Zhou G. Innate responses to gene knockouts impact overlapping gene networks and vary with respect to resistance to viral infection. Proc Natl Acad Sci U S A. 2018;115:E3230-E3237 pubmed publisher
	Jie C, Luo Z, Chen H, Wang M, Yan C, Mao Z, et al. Indirubin, a bisindole alkaloid from Isatis indigotica, reduces H1N1 susceptibility in stressed mice by regulating MAVS signaling. Oncotarget. 2017;8:105615-105629 pubmed publisher
	Takahama M, Fukuda M, Ohbayashi N, Kozaki T, Misawa T, Okamoto T, et al. The RAB2B-GARIL5 Complex Promotes Cytosolic DNA-Induced Innate Immune Responses. Cell Rep. 2017;20:2944-2954 pubmed publisher
	Wang J, Kang L, Song D, Liu L, Yang S, Ma L, et al. Ku70 Senses HTLV-1 DNA and Modulates HTLV-1 Replication. J Immunol. 2017;199:2475-2482 pubmed publisher
	Bhatelia K, Singh K, Prajapati P, Sripada L, Roy M, Singh R. MITA modulated autophagy flux promotes cell death in breast cancer cells. Cell Signal. 2017;35:73-83 pubmed publisher
	Song S, Peng P, Tang Z, Zhao J, Wu W, Li H, et al. Decreased expression of STING predicts poor prognosis in patients with gastric cancer. Sci Rep. 2017;7:39858 pubmed publisher
	Wang J, Yang S, Liu L, Wang H, Yang B. HTLV-1 Tax impairs K63-linked ubiquitination of STING to evade host innate immunity. Virus Res. 2017;232:13-21 pubmed publisher
	Liu Y, Li J, Chen J, Li Y, Wang W, Du X, et al. Hepatitis B virus polymerase disrupts K63-linked ubiquitination of STING to block innate cytosolic DNA-sensing pathways. J Virol. 2015;89:2287-300 pubmed publisher

product information

CatalogNo :

19851-1-AP

AntigenName :

TMEM173/STING

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

transmembrane protein 173

Immunogen :

Fusion Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, FC, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

hMITA, hSTING, Mediator of IRF3 activation, MITA, MPYS, NET23, STING, TMEM173, transmembrane protein 173

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC047779

Category :

Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Membrane Proteins;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

FC 1:0 ; IF 1:50 ; IHC 1:100 ; IP 1:1000 ; WB 1:2000 ;