NLRP3 | Proteintech Group 19771-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

NLRP3

catalog :

19771-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry

citations: 51

Reference
Zou Y, Xu J, Wang X, Zhu Y, Wu Q, Wang J. Lactobacillus johnsonii L531 Ameliorates Escherichia coli-Induced Cell Damage via Inhibiting NLRP3 Inflammasome Activity and Promoting ATG5/ATG16L1-Mediated Autophagy in Porcine Mammary Epithelial Cells. Vet Sci. 2020;7: pubmed publisher
Xie T, Wang C, Jin Y, Meng Q, Liu Q, Wu J, et al. CoenzymeQ10-Induced Activation of AMPK-YAP-OPA1 Pathway Alleviates Atherosclerosis by Improving Mitochondrial Function, Inhibiting Oxidative Stress and Promoting Energy Metabolism. Front Pharmacol. 2020;11:1034 pubmed publisher
Guo L, Liu S, Yang Q, Liu H, Xu L, Hao Y, et al. Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice. Biomed Res Int. 2020;2020:1594726 pubmed publisher
Zhao W, Deng C, Han Q, Xu H, Chen Y. Carvacrol may alleviate vascular inflammation in diabetic db/db mice. Int J Mol Med. 2020;46:977-988 pubmed publisher
Guan L, Li C, Zhang Y, Gong J, Wang G, Tian P, et al. Puerarin ameliorates retinal ganglion cell damage induced by retinal ischemia/reperfusion through inhibiting the activation of TLR4/NLRP3 inflammasome. Life Sci. 2020;256:117935 pubmed publisher
Li S, Shi M, Wan Y, Wang Y, Zhu M, Wang B, et al. Inflammasome/NF-κB translocation inhibition via PPARγ agonist mitigates inorganic mercury induced nephrotoxicity. Ecotoxicol Environ Saf. 2020;201:110801 pubmed publisher
Wang J, Zheng B, Yang S, Tang X, Wang J, Wei D. The protective effects of phoenixin-14 against lipopolysaccharide-induced inflammation and inflammasome activation in astrocytes. Inflamm Res. 2020;69:779-787 pubmed publisher
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, et al. TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury. Cell Prolif. 2020;53:e12829 pubmed publisher
Huang G, Bao J, Shao X, Zhou W, Wu B, Ni Z, et al. Inhibiting pannexin-1 alleviates sepsis-induced acute kidney injury via decreasing NLRP3 inflammasome activation and cell apoptosis. Life Sci. 2020;254:117791 pubmed publisher
Gao Y, Li J, Li J, Hu C, Zhang L, Yan J, et al. Tetrahydroxy stilbene glycoside alleviated inflammatory damage by mitophagy via AMPK related PINK1/Parkin signaling pathway. Biochem Pharmacol. 2020;177:113997 pubmed publisher
Pang H, Wang N, Chai J, Wang X, Zhang Y, Bi Z, et al. Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury. Eur J Med Chem. 2020;197:112314 pubmed publisher
Xie C, Ge M, Jin J, Xu H, Mao L, Geng S, et al. Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK. J Hazard Mater. 2020;394:122549 pubmed publisher
Xing S, Yang J, Li W, Li J, Chen L, Yang Y, et al. Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis. Inflammation. 2020;43:433-440 pubmed publisher
Wang X, Chi J, Huang D, Ding L, Zhao X, Jiang L, et al. α-synuclein promotes progression of Parkinson's disease by upregulating autophagy signaling pathway to activate NLRP3 inflammasome. Exp Ther Med. 2020;19:931-938 pubmed publisher
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y. Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice. Int Immunopharmacol. 2020;80:106123 pubmed publisher
Xia B, Yu J, He T, Liu X, Su J, Wang M, et al. Lactobacillus johnsonii L531 ameliorates enteritis via elimination of damaged mitochondria and suppression of SQSTM1-dependent mitophagy in a Salmonella infantis model of piglet diarrhea. FASEB J. 2020;34:2821-2839 pubmed publisher
Guo M, Yan R, Yao H, Duan L, Sun M, Xue Z, et al. IFN Regulatory Factor 1 Mediates Macrophage Pyroptosis Induced by Oxidized Low-Density Lipoprotein in Patients with Acute Coronary Syndrome. Mediators Inflamm. 2019;2019:2917128 pubmed publisher
Hu Y, Li Q, Pan Y, Xu L. Sal B Alleviates Myocardial Ischemic Injury by Inhibiting TLR4 and the Priming Phase of NLRP3 Inflammasome. Molecules. 2019;24: pubmed publisher
Liu S, Wu X, Hua T, Xin X, Feng D, Chi S, et al. NLRP3 inflammasome activation by estrogen promotes the progression of human endometrial cancer. Onco Targets Ther. 2019;12:6927-6936 pubmed publisher
Wu M, Li P, An Y, Ren J, Yan D, Cui J, et al. Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota. Pharmacol Res. 2019;150:104489 pubmed publisher
Si L, Fu J, Liu W, Hayashi T, Nie Y, Mizuno K, et al. Silibinin inhibits migration and invasion of breast cancer MDA-MB-231 cells through induction of mitochondrial fusion. Mol Cell Biochem. 2019;: pubmed publisher
Jia C, Zhang J, Chen H, Zhuge Y, Chen H, Qian F, et al. Endothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation. Cell Death Dis. 2019;10:778 pubmed publisher
Ershaid N, Sharon Y, Doron H, Raz Y, Shani O, Cohen N, et al. NLRP3 inflammasome in fibroblasts links tissue damage with inflammation in breast cancer progression and metastasis. Nat Commun. 2019;10:4375 pubmed publisher
Hou C, Zhu X, Shi C, Peng Y, Huang D, Li Q, et al. Iguratimod (T-614) attenuates severe acute pancreatitis by inhibiting the NLRP3 inflammasome and NF-κB pathway. Biomed Pharmacother. 2019;119:109455 pubmed publisher
Zeng R, Luo D, Li H, Zhang Q, Lei S, Chen J. MicroRNA-135b alleviates MPP+-mediated Parkinson's disease in in vitro model through suppressing FoxO1-induced NLRP3 inflammasome and pyroptosis. J Clin Neurosci. 2019;65:125-133 pubmed publisher
Yu J, Lin Y, Xiong X, Li K, Yao Z, Dong H, et al. Detection of Exosomal PD-L1 RNA in Saliva of Patients With Periodontitis. Front Genet. 2019;10:202 pubmed publisher
Wang K, Xu T, Ruan H, Xiao H, Liu J, Song Z, et al. LXRα promotes cell metastasis by regulating the NLRP3 inflammasome in renal cell carcinoma. Cell Death Dis. 2019;10:159 pubmed publisher
Chen L, He P, Yang J, Yang Y, Wang K, Amend B, et al. NLRP3/IL1β inflammasome associated with the aging bladder triggers bladder dysfunction in female rats. Mol Med Rep. 2019;19:2960-2968 pubmed publisher
Hua S, Ma M, Fei X, Zhang Y, Gong F, Fang M. Glycyrrhizin attenuates hepatic ischemia-reperfusion injury by suppressing HMGB1-dependent GSDMD-mediated kupffer cells pyroptosis. Int Immunopharmacol. 2019;68:145-155 pubmed publisher
Du L, Shen K, Bai Y, Chao J, Hu G, Zhang Y, et al. Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis. Toxicol Lett. 2019;301:53-63 pubmed publisher
Liu H, Sun Y, Zhang Y, Yang G, Guo L, Zhao Y, et al. Role of Thymoquinone in Cardiac Damage Caused by Sepsis from BALB/c Mice. Inflammation. 2019;42:516-525 pubmed publisher
Ran S, Chu M, Gu S, Wang J, Liang J. Enterococcus faecalis induces apoptosis and pyroptosis of human osteoblastic MG63 cells via the NLRP3 inflammasome. Int Endod J. 2019;52:44-53 pubmed publisher
Bando H, Lee Y, Sakaguchi N, Pradipta A, Ma J, Tanaka S, et al. Inducible Nitric Oxide Synthase Is a Key Host Factor for Toxoplasma GRA15-Dependent Disruption of the Gamma Interferon-Induced Antiparasitic Human Response. MBio. 2018;9: pubmed publisher
Zheng T, Yang X, Li W, Wang Q, Chen L, Wu D, et al. Salidroside Attenuates High-Fat Diet-Induced Nonalcoholic Fatty Liver Disease via AMPK-Dependent TXNIP/NLRP3 Pathway. Oxid Med Cell Longev. 2018;2018:8597897 pubmed publisher
Wu Q, Zhu Y, Xu J, Liu X, Duan C, Wang M, et al. Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Activation of NLRP3 and NLRC4 Inflammasomes With Differential Requirement for ASC. Front Microbiol. 2018;9:1661 pubmed publisher
Guo Q, Wu Y, Hou Y, Liu Y, Liu T, Zhang H, et al. Cytokine Secretion and Pyroptosis of Thyroid Follicular Cells Mediated by Enhanced NLRP3, NLRP1, NLRC4, and AIM2 Inflammasomes Are Associated With Autoimmune Thyroiditis. Front Immunol. 2018;9:1197 pubmed publisher
Yang R, Cai T, Wu X, Liu Y, He J, Zhang X, et al. Tumour YAP1 and PTEN expression correlates with tumour-associated myeloid suppressor cell expansion and reduced survival in colorectal cancer. Immunology. 2018;155:263-272 pubmed publisher
Stødle G, Silva G, Tangerås L, Gierman L, Nervik I, Dahlberg U, et al. Placental inflammation in pre-eclampsia by Nod-like receptor protein (NLRP)3 inflammasome activation in trophoblasts. Clin Exp Immunol. 2018;193:84-94 pubmed publisher
Zhuang W, Wang C, Shi X, Qiu S, Zhang S, Xu B, et al. MCMV triggers ROS/NLRP3-associated inflammasome activation in the inner ear of mice and cultured spiral ganglion neurons, contributing to sensorineural hearing loss. Int J Mol Med. 2018;41:3448-3456 pubmed publisher
Wu X, Zhang H, Qi W, Zhang Y, Li J, Li Z, et al. Nicotine promotes atherosclerosis via ROS-NLRP3-mediated endothelial cell pyroptosis. Cell Death Dis. 2018;9:171 pubmed publisher
Yu J, Zhu Y, Yang G, Zhang W, Zhou D, Su J, et al. Anti-inflammatory capacity of Lactobacillus rhamnosus GG in monophasic variant Salmonella infected piglets is correlated with impeding NLRP6-mediated host inflammatory responses. Vet Microbiol. 2017;210:91-100 pubmed publisher
Guo M, An F, Yu H, Wei X, Hong M, Lu Y. Comparative effects of schisandrin A, B, and C on Propionibacterium acnes-induced, NLRP3 inflammasome activation-mediated IL-1? secretion and pyroptosis. Biomed Pharmacother. 2017;96:129-136 pubmed publisher
Zhang Y, Lv X, Hu Z, Ye X, Zheng X, Ding Y, et al. Protection of Mcc950 against high-glucose-induced human retinal endothelial cell dysfunction. Cell Death Dis. 2017;8:e2941 pubmed publisher
Zhou Z, Wang Z, Guan Q, Qiu F, Li Y, Liu Z, et al. PEDF Inhibits the Activation of NLRP3 Inflammasome in Hypoxia Cardiomyocytes through PEDF Receptor/Phospholipase A2. Int J Mol Sci. 2016;17: pubmed
Shen J, Wang L, Jiang N, Mou S, Zhang M, Gu L, et al. NLRP3 inflammasome mediates contrast media-induced acute kidney injury by regulating cell apoptosis. Sci Rep. 2016;6:34682 pubmed publisher
Ding C, Zhao Y, Shi X, Zhang N, Zu G, Li Z, et al. New insights into salvianolic acid A action: Regulation of the TXNIP/NLRP3 and TXNIP/ChREBP pathways ameliorates HFD-induced NAFLD in rats. Sci Rep. 2016;6:28734 pubmed publisher
Fang H, Shao S, Cao T, Lei J, Dang E, Zhang J, et al. Increased expression of NLRP3 inflammasome components and interleukin-18 in patients with bullous pemphigoid. J Dermatol Sci. 2016;83:116-23 pubmed publisher
Gao Z, Han Y, Hu Y, Wu X, WANG Y, Zhang X, et al. Targeting HO-1 by Epigallocatechin-3-Gallate Reduces Contrast-Induced Renal Injury via Anti-Oxidative Stress and Anti-Inflammation Pathways. PLoS ONE. 2016;11:e0149032 pubmed publisher
Wu Q, Liu M, Yang J, Wang J, Zhu Y. Lactobacillus rhamnosus GR-1 Ameliorates Escherichia coli-Induced Inflammation and Cell Damage via Attenuation of ASC-Independent NLRP3 Inflammasome Activation. Appl Environ Microbiol. 2016;82:1173-1182 pubmed publisher
E Q, Tang M, Zhang X, Shi Y, Wang D, Gu Y, et al. Protection of seven dibenzocyclooctadiene lignans from Schisandra chinensis against serum and glucose deprivation injury in SH-SY5Y cells. Cell Biol Int. 2015;39:1418-24 pubmed publisher
Peng K, Liu L, Wei D, Lv Y, Wang G, Xiong W, et al. P2X7R is involved in the progression of atherosclerosis by promoting NLRP3 inflammasome activation. Int J Mol Med. 2015;35:1179-88 pubmed publisher

product information

CatalogNo :

19771-1-AP

AntigenName :

NLRP3

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

NLR family, pyrin domain containing 3

Immunogen :

Peptide

Species :

cow, human, mouse, rat, swine

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IHC, IF, CoIP, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

AGTAVPRL, AII, AII/AVP, AVP, C1orf7, Caterpiller protein 1.1, CIAS1, CLR1.1, Cryopyrin, FCAS, FCU, MWS, NALP3, NLRP3, PYPAF1

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

NM_001127461

Category :

Apoptosis;Binding Proteins;Neurology;Signal transduction;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IHC 1:200 ; WB 1:1000 ;