| Published Application/Species/Sample/Dilution | Reference |
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- western blot; mouse; 1:1000; loading ...; fig 2d
| Liu D, Bai X, Ma W, Xin D, Chu X, Yuan H, et al. Purmorphamine Attenuates Neuro-Inflammation and Synaptic Impairments After Hypoxic-Ischemic Injury in Neonatal Mice via Shh Signaling. Front Pharmacol. 2020;11:204 pubmed publisher |
- western blot; human; 1:500; loading ...; fig 3f
| Chen Z, Zhang J, Xue H, Qian M, Guo X, Gao X, et al. Nitidine Chloride Is a Potential Alternative Therapy for Glioma Through Inducing Endoplasmic Reticulum Stress and Alleviating Epithelial-Mesenchymal Transition. Integr Cancer Ther. 2020;19:1534735419900927 pubmed publisher |
- western blot; rat; loading ...; fig 4c
| Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher |
- western blot; human; 1:10,000; loading ...; fig 6a
| Li F, Wu J, Wang P, Qu L. NKAP functions as an oncogene in Ewing sarcoma cells partly through the AKT signaling pathway. Exp Ther Med. 2019;18:3037-3045 pubmed publisher |
- western blot; human; 1:10,000; loading ...; fig 6a
| Ma Y, Guan L, Han Y, Zhou Y, Li X, Liu Y, et al. siPRDX2-elevated DNM3 inhibits the proliferation and metastasis of colon cancer cells via AKT signaling pathway. Cancer Manag Res. 2019;11:5799-5811 pubmed publisher |
- western blot; human; 1:2000; loading ...; fig 3d
| Suo L, Chang X, Xu N, Ji H. The Anti-proliferative Activity of GnRH Through Downregulation of the Akt/ERK Pathways in Pancreatic Cancer. Front Endocrinol (Lausanne). 2019;10:370 pubmed publisher |
- western blot; human; 1:1000; loading ...; fig 1f
| Feng J, Wu L, Ji J, Chen K, Yu Q, Zhang J, et al. PKM2 is the target of proanthocyanidin B2 during the inhibition of hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:204 pubmed publisher |
- western blot; mouse; 1:500; loading ...; fig 8a
| Zhu F, Yan P, Zhang J, Cui Y, Zheng M, Cheng Y, et al. Deficiency of TPPP2, a factor linked to oligoasthenozoospermia, causes subfertility in male mice. J Cell Mol Med. 2019;23:2583-2594 pubmed publisher |
- western blot; human; loading ...; fig 5b
| Chen L, Yang G, Dong H. Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway. Med Sci Monit. 2019;25:77-86 pubmed publisher |
- western blot; mouse; loading ...; fig 5c
| Dong Q, Li J, Wu Q, Zhao N, Qian C, Ding D, et al. Blockage of transient receptor potential vanilloid 4 alleviates myocardial ischemia/reperfusion injury in mice. Sci Rep. 2017;7:42678 pubmed publisher |
- western blot; mouse; loading ...; fig 3a
| Li J, Chen K, Li S, Liu T, Wang F, Xia Y, et al. Pretreatment with Fucoidan from Fucus vesiculosus Protected against ConA-Induced Acute Liver Injury by Inhibiting Both Intrinsic and Extrinsic Apoptosis. PLoS ONE. 2016;11:e0152570 pubmed publisher |
- western blot; mouse; 1:1000; loading ...; fig 3c
| Lei X, Cui K, Liu Q, Zhang H, Li Z, Huang B, et al. Exogenous Estradiol Benzoate Induces Spermatogenesis Disorder through Influencing Apoptosis and Oestrogen Receptor Signalling Pathway. Reprod Domest Anim. 2016;51:75-84 pubmed publisher |
- western blot; human; 1:500
| Zhang X, Pan Q, Pan K, Weng D, Wang Q, Zhao J, et al. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog. 2016;55:64-76 pubmed publisher |
| Yan B, Zhang X, Wang J, Jia S, Zhou Y, Tian J, et al. Inhibitory effect of Lycium barbarum polysaccharide on sperm damage during cryopreservation. Exp Ther Med. 2020;20:3051-3063 pubmed publisher |
| Wang P, Wang X, Tang Q, Chen H, Zhang Q, Jiang H, et al. Functionalized graphene oxide against U251 glioma cells and its molecular mechanism. Mater Sci Eng C Mater Biol Appl. 2020;116:111187 pubmed publisher |
| Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, et al. Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy. Exp Ther Med. 2020;20:1889-1898 pubmed publisher |
| Zhang P, Cao M, Zhang Y, Xu L, Meng F, Wu X, et al. A novel antisense lncRNA NT5E promotes progression by modulating the expression of SYNCRIP and predicts a poor prognosis in pancreatic cancer. J Cell Mol Med. 2020;: pubmed publisher |
| Hu Z, Wang H, Fu Y, Ma K, Ma X, Wang J. Gentiopicroside Inhibits Cell Growth and Migration on Cervical Cancer via the Reciprocal MAPK/Akt Signaling Pathways. Nutr Cancer. 2020;:1-12 pubmed publisher |
| Li Y, Zhang M, Li F. LncRNA AY343892 inhibits breast cancer development by positively regulating BRCA1-mediated transcription of PTEN. Histol Histopathol. 2020;:18245 pubmed publisher |
| Liu J, Yang X, Liang Q, Yu Y, Shen X, Sun G. Valproic acid overcomes sorafenib resistance by reducing the migration of Jagged2-mediated Notch1 signaling pathway in hepatocellular carcinoma cells. Int J Biochem Cell Biol. 2020;126:105820 pubmed publisher |
| Mou J, Xu J, Wang Z, Wang C, Yang X, Wang X, et al. Effects of photoperiod on morphology and function in testis and epididymis of Cricetulus barabensis. J Cell Physiol. 2020;: pubmed publisher |
| Yao Q, Zhou Y, Yang Y, Cai L, Xu L, Han X, et al. Activation of Sirtuin1 by lyceum barbarum polysaccharides in protection against diabetic cataract. J Ethnopharmacol. 2020;261:113165 pubmed publisher |
| Wang C, Yang J, Guo Y, Shen J, Pei X. Anticancer Activity of Tetrandrine by Inducing Apoptosis in Human Breast Cancer Cell Line MDA-MB-231 In Vivo. Evid Based Complement Alternat Med. 2020;2020:6823520 pubmed publisher |
| An K, Zhang Y, Liu Y, Yan S, Hou Z, Cao M, et al. Neferine induces apoptosis by modulating the ROS‑mediated JNK pathway in esophageal squamous cell carcinoma. Oncol Rep. 2020;44:1116-1126 pubmed publisher |
| Wang X, Lin Y, Zheng Y. Antitumor effects of aconitine in A2780 cells via estrogen receptor β‑mediated apoptosis, DNA damage and migration. Mol Med Rep. 2020;22:2318-2328 pubmed publisher |
| Wo X, Yuan Y, Xu Y, Chen Y, Wang Y, Zhao S, et al. TAR DNA-Binding Protein 43 is Cleaved by the Protease 3C of Enterovirus A71. Virol Sin. 2020;: pubmed publisher |
| Shi J, Xiao P, Liu X, Chen Y, Xu Y, Fan J, et al. Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis. Front Physiol. 2020;11:669 pubmed publisher |
| Guo L, Liu S, Yang Q, Liu H, Xu L, Hao Y, et al. Effect of Thymoquinone on Acute Kidney Injury Induced by Sepsis in BALB/c Mice. Biomed Res Int. 2020;2020:1594726 pubmed publisher |
| Liu J, Deng X, Sun X, Dong J, Huang J. Inhibition of autophagy enhances timosaponin AIII-induced lung cancer cell apoptosis and anti-tumor effect in vitro and in vivo. Life Sci. 2020;257:118040 pubmed publisher |
| Zhao Y, Tang J, Yang D, Tang C, Chen J. Staphylococcal enterotoxin M induced inflammation and impairment of bovine mammary epithelial cells. J Dairy Sci. 2020;103:8350-8359 pubmed publisher |
| Li C, Meng X, Liu S, Li W, Zhang X, Zhou J, et al. Oocytes and hypoxanthine orchestrate the G2-M switch mechanism in ovarian granulosa cells. Development. 2020;147: pubmed publisher |
| Xin D, Li T, Chu X, Ke H, Yu Z, Cao L, et al. Mesenchymal stromal cell-derived extracellular vesicles modulate microglia/macrophage polarization and protect the brain against hypoxia-ischemic injury in neonatal mice by targeting delivery of miR-21a-5p. Acta Biomater. 2020;113:597-613 pubmed publisher |
| Fang H, Yang K, Tang P, Zhao N, Ma R, Luo X, et al. Glycosylation end products mediate damage and apoptosis of periodontal ligament stem cells induced by the JNK-mitochondrial pathway. Aging (Albany NY). 2020;12:12850-12868 pubmed publisher |
| Yuan M, Yang X, Duscher D, Xiong H, Ren S, Xu X, et al. Overexpression of microRNA-21-5p prevents the oxidative stress-induced apoptosis of RSC96 cells by suppressing autophagy. Life Sci. 2020;256:118022 pubmed publisher |
| Fan J, Tian L, Huang S, Zhang J, Zhao B. Derlin-1 Promotes the Progression of Human Hepatocellular Carcinoma via the Activation of AKT Pathway. Onco Targets Ther. 2020;13:5407-5417 pubmed publisher |
| Su P, Ahmad B, Zou K, Zou L. β-Elemene Enhances the Chemotherapeutic Effect of 5-Fluorouracil in Triple-Negative Breast Cancer via PI3K/AKT, RAF-MEK-ErK, and NF-κB Signaling Pathways. Onco Targets Ther. 2020;13:5207-5222 pubmed publisher |
| Hao Y, Huang Y, Chen J, Li J, Yuan Y, Wang M, et al. Exopolysaccharide from Cryptococcus heimaeyensis S20 induces autophagic cell death in non-small cell lung cancer cells via ROS/p38 and ROS/ERK signalling. Cell Prolif. 2020;53:e12869 pubmed publisher |
| Tian R, Jiang H, Shao L, Yu Y, Guo Q, Cao B, et al. miR193b Promotes Apoptosis of Gastric Cancer Cells via Directly Mediating the Akt Pathway. Biomed Res Int. 2020;2020:2863236 pubmed publisher |
| Cui Y, Chen R, Ma L, Yang W, Chen M, Zhang Y, et al. miR-205 Expression Elevated With EDS Treatment and Induced Leydig Cell Apoptosis by Targeting RAP2B via the PI3K/AKT Signaling Pathway. Front Cell Dev Biol. 2020;8:448 pubmed publisher |
| Li T, Wu S, Jia L, Cao W, Yao Y, Zhao G, et al. CUL4 E3 ligase regulates the proliferation and apoptosis of lung squamous cell carcinoma and small cell lung carcinoma. Cancer Biol Med. 2020;17:357-370 pubmed publisher |
| Shi Z, Wang Q, Zhang Y, Jiang D. Extracellular vesicles produced by bone marrow mesenchymal stem cells attenuate renal fibrosis, in part by inhibiting the RhoA/ROCK pathway, in a UUO rat model. Stem Cell Res Ther. 2020;11:253 pubmed publisher |
| Hu X, Xia M, Wang J, Yu H, Chai J, Zhang Z, et al. Dual PI3K/mTOR inhibitor PKI-402 suppresses the growth of ovarian cancer cells by degradation of Mcl-1 through autophagy. Biomed Pharmacother. 2020;129:110397 pubmed publisher |
| Zhao S, Xiao P, Cui H, Gong P, Lin C, Chen F, et al. Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery. Front Mol Neurosci. 2020;13:100 pubmed publisher |
| Wu B, Jiang M, Liu X, Huang C, Gu Z, Cao Y. Evaluation of toxicity of halloysite nanotubes and multi-walled carbon nanotubes to endothelial cells in vitro and blood vessels in vivo. Nanotoxicology. 2020;:1-22 pubmed publisher |
| Liu J, Shangguan Y, Sun J, Cong W, Xie Y. BAIAP2L2 promotes the progression of gastric cancer via AKT/mTOR and Wnt3a/β-catenin signaling pathways. Biomed Pharmacother. 2020;129:110414 pubmed publisher |
| Liu Z, Li C, Wu G, Li W, Zhang X, Zhou J, et al. Involvement of JNK/FOXO1 pathway in apoptosis induced by severe hypoxia in porcine granulosa cells. Theriogenology. 2020;154:120-127 pubmed publisher |
| Cui L, Xu F, Wu K, Li L, Qiao T, Li Z, et al. Anticancer effects and possible mechanisms of lycopene intervention on N-methylbenzylnitrosamine induced esophageal cancer in F344 rats based on PPARγ1. Eur J Pharmacol. 2020;881:173230 pubmed publisher |
| Wang Y, Li C, Li J, Wang G, Li L. Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher |
| Zhao H, Wang Y, Li B, Zheng T, Liu X, Hu B, et al. Role of Endoplasmic Reticulum Stress in Otitis Media. Front Genet. 2020;11:495 pubmed publisher |
| Yu M, Ren L, Liang F, Zhang Y, Jiang L, Ma W, et al. Effect of epiberberine from Coptis chinensis Franch on inhibition of tumor growth in MKN-45 xenograft mice. Phytomedicine. 2020;76:153216 pubmed publisher |
| Guo Y, Zhu H, Weng M, Chen B, Wang C, Sun L. Baohuoside-1 targeting mTOR inducing apoptsis to inhibit hepatocellular carcinoma proliferation, invasion and migration. Biomed Pharmacother. 2020;128:110366 pubmed publisher |
| Dong X, Kong F, Liu C, Dai S, Zhang Y, Xiao F, et al. Pulp stem cells with hepatocyte growth factor overexpression exhibit dual effects in rheumatoid arthritis. Stem Cell Res Ther. 2020;11:229 pubmed publisher |
| Han B, Jiang L, Jiang P, Zhou D, Jia X, Li X, et al. Daucosterol linolenate from Sweet Potato Suppresses MCF7-Xenograft-Tumor Growth through Regulating PI3K/AKT Pathway. Planta Med. 2020;86:767-775 pubmed publisher |
| Wu J, He J, Tian X, Li H, Wen Y, Shao Q, et al. Upregulation of miRNA-9-5p Promotes Angiogenesis after Traumatic Brain Injury by Inhibiting Ptch-1. Neuroscience. 2020;440:160-174 pubmed publisher |
| Tan X, Li T, Zhu S, Zhong W, Li F, Wang Y. Induction of SPARC on Oxidative Stress, Inflammatory Phenotype Transformation, and Apoptosis of Human Brain Smooth Muscle Cells Via TGF-β1-NOX4 Pathway. J Mol Neurosci. 2020;: pubmed publisher |
| Dong D, Dong Y, Fu J, Lu S, Yuan C, Xia M, et al. Bcl2 inhibitor ABT737 reverses the Warburg effect via the Sirt3-HIF1α axis to promote oxidative stress-induced apoptosis in ovarian cancer cells. Life Sci. 2020;255:117846 pubmed publisher |
| Liu Q, Tan Y, Qu T, Zhang J, Duan X, Xu H, et al. Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro. Life Sci. 2020;254:117772 pubmed publisher |
| Cao Y, Liu C, Wang Q, Wang W, Tao E, Wan L. Pum2 mediates Sirt1 mRNA decay and exacerbates hypoxia/reoxygenation-induced cardiomyocyte apoptosis. Exp Cell Res. 2020;393:112058 pubmed publisher |
| Yang S, Wang M, Yang L, Li Y, Ma Y, Peng X, et al. MicroRNA-375 Targets ATG14 to Inhibit Autophagy and Sensitize Hepatocellular Carcinoma Cells to Sorafenib. Onco Targets Ther. 2020;13:3557-3570 pubmed publisher |
| Hou B, Zhang Y, Liang P, He Y, Peng B, Liu W, et al. Inhibition of the NLRP3-inflammasome prevents cognitive deficits in experimental autoimmune encephalomyelitis mice via the alteration of astrocyte phenotype. Cell Death Dis. 2020;11:377 pubmed publisher |
| Ma J, Qi J, Li S, Zhang C, Wang H, Shao L, et al. Desloratadine, a Novel Antigrowth Reagent for Bladder Cancer. Technol Cancer Res Treat. 2020;19:1533033820926591 pubmed publisher |
| Zhang K, Rui G, Zhang J, Guo L, An G, Lin J, et al. Cathodal tDCS exerts neuroprotective effect in rat brain after acute ischemic stroke. BMC Neurosci. 2020;21:21 pubmed publisher |
| Chu X, Zhang Y, Xue Y, Li Z, Shi J, Wang H, et al. Crocin protects against cardiotoxicity induced by doxorubicin through TLR-2/NF-κB signal pathway in vivo and vitro. Int Immunopharmacol. 2020;84:106548 pubmed publisher |
| Hu Z, Long T, Ma Y, Zhu J, Gao L, Zhong Y, et al. Downregulation of GLYR1 contributes to microsatellite instability colorectal cancer by targeting p21 via the p38MAPK and PI3K/AKT pathways. J Exp Clin Cancer Res. 2020;39:76 pubmed publisher |
| Huang L, Yan W, Cai B, Song Y, Lv Q, Wang G, et al. Dual-engineered, "Trojanized" macrophages bio-modally eradicate tumors through biologically and photothermally deconstructing cancer cells in an on-demand, NIR-commanded, self-explosive manner. Biomaterials. 2020;250:120021 pubmed publisher |
| Wang L, Lv Y, Liu G. The roles of SHANK1 in the development of colon cancer. Cell Biochem Funct. 2020;: pubmed publisher |
| Meng X, Zhang C, Guo Y, Han Y, Wang C, Chu H, et al. TBHQ Attenuates Neurotoxicity Induced by Methamphetamine in the VTA through the Nrf2/HO-1 and PI3K/AKT Signaling Pathways. Oxid Med Cell Longev. 2020;2020:8787156 pubmed publisher |
| Ji J, Wu L, Feng J, Mo W, Wu J, Yu Q, et al. Cafestol preconditioning attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting ERK/PPARγ pathway. Int Immunopharmacol. 2020;84:106529 pubmed publisher |
| Pang H, Wang N, Chai J, Wang X, Zhang Y, Bi Z, et al. Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury. Eur J Med Chem. 2020;197:112314 pubmed publisher |
| Nakano D, Kawaguchi T, Iwamoto H, Hayakawa M, Koga H, Torimura T. Effects of canagliflozin on growth and metabolic reprograming in hepatocellular carcinoma cells: Multi-omics analysis of metabolomics and absolute quantification proteomics (iMPAQT). PLoS ONE. 2020;15:e0232283 pubmed publisher |
| Chen H, Liang F, Gu P, Xu B, Xu H, Wang W, et al. Exosomes derived from mesenchymal stem cells repair a Parkinson's disease model by inducing autophagy. Cell Death Dis. 2020;11:288 pubmed publisher |
| Yang Z, Li J, Chen W, Kong F. Oncogenic gene RGC-32 is a direct target of miR-26b and facilitates tongue squamous cell carcinoma aggressiveness through EMT and PI3K/AKT signalling. Cell Biochem Funct. 2020;: pubmed publisher |
| Huang B, Liu J, Fu S, Zhang Y, Li Y, He D, et al. α-Cyperone Attenuates H2O2-Induced Oxidative Stress and Apoptosis in SH-SY5Y Cells via Activation of Nrf2. Front Pharmacol. 2020;11:281 pubmed publisher |
| Yang T, Fan T, Xu B. Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells. Toxicol In Vitro. 2020;66:104868 pubmed publisher |
| Mao L, Kan Y, Li B, Ma S, Liu Y, Yang D, et al. Combination Therapy of Prostate Cancer by Oncolytic Adenovirus Harboring Interleukin 24 and Ionizing Radiation. Front Oncol. 2020;10:421 pubmed publisher |
| Huang G, Ma J, Zhang L. Integrin Subunit Alpha 5 (ITGA5) Gene Circular RNA Sponges microRNA-107 in Colorectal Carcinoma Cells and Tissues and Regulates the Expression of the Forkhead Box J3 (FOXJ3) Gene. Med Sci Monit. 2020;26:e920623 pubmed publisher |
| Zhu Y, Shi F, Wang M, Ding J. Knockdown of Rab9 Suppresses the Progression of Gastric Cancer Through Regulation of Akt Signaling Pathway. Technol Cancer Res Treat. 2020;19:1533033820915958 pubmed publisher |
| Wu J, Gan Z, Zhuo R, Zhang L, Wang T, Zhong X. Resveratrol Attenuates Aflatoxin B1-Induced ROS Formation and Increase of m6A RNA Methylation. Animals (Basel). 2020;10: pubmed publisher |
| He S, Li A, Zhang W, Zhang L, Liu Y, Li K, et al. An integrated transcriptomics and network pharmacology approach to exploring the mechanism of adriamycin-induced kidney injury. Chem Biol Interact. 2020;325:109096 pubmed publisher |
| Zuo A, Li J, Zhao X, Li T, Lei S, Chen J, et al. Globular CTRP9 protects cardiomyocytes from palmitic acid-induced oxidative stress by enhancing autophagic flux. Chem Biol Interact. 2020;:109094 pubmed publisher |
| Huang J, Hou B, Zhang S, Wang M, Lu X, Wang Q, et al. The Protective Effect of Adiponectin-Transfected Endothelial Progenitor Cells on Cognitive Function in D-Galactose-Induced Aging Rats. Neural Plast. 2020;2020:1273198 pubmed publisher |
| Jing X, Chen Y, Chen Y, Shi G, Lv S, Cheng N, et al. Down-regulation of USP8 Inhibits Cholangiocarcinoma Cell Proliferation and Invasion. Cancer Manag Res. 2020;12:2185-2194 pubmed publisher |
| Shi B, Huang Y, Ni J, Chen J, Wei J, Gao H, et al. Qi Dan Li Xin pill improves chronic heart failure by regulating mTOR/p70S6k-mediated autophagy and inhibiting apoptosis. Sci Rep. 2020;10:6105 pubmed publisher |
| Peng F, Li G, Xie Y, Yin H, Li X, Yang Y. Compositional characterization of Pyrus ussuriensis Maxim and their antioxidant activities and induction of apoptosis in Bel-7402 cell. J Food Biochem. 2020;44:e13222 pubmed publisher |
| Liu Y, Liu S, Wu C, Huang W, Xu B, Lian S, et al. PD-1-Mediated PI3K/Akt/mTOR, Caspase 9/Caspase 3 and ERK Pathways Are Involved in Regulating the Apoptosis and Proliferation of CD4+ and CD8+ T Cells During BVDV Infection in vitro. Front Immunol. 2020;11:467 pubmed publisher |
| Almoiliqy M, Wen J, Xu B, Sun Y, Lian M, Li Y, et al. Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53. Acta Pharmacol Sin. 2020;41:1208-1222 pubmed publisher |
| Su Q, Wang J, Liu F, Zhang Y. Blocking Parkin/PINK1-mediated mitophagy sensitizes hepatocellular carcinoma cells to sanguinarine-induced mitochondrial apoptosis. Toxicol In Vitro. 2020;66:104840 pubmed publisher |
| Yang Y, Yu S, Jia B, Liu N, Wu A. Metabolomic profiling reveals similar cytotoxic effects and protective functions of quercetin during deoxynivalenol- and 15-acetyl deoxynivalenol-induced cell apoptosis. Toxicol In Vitro. 2020;66:104838 pubmed publisher |
| Zhang L, Xu H, Ma C, Zhang J, Zhao Y, Yang X, et al. Upregulation of deubiquitinase PSMD14 in lung adenocarcinoma (LUAD) and its prognostic significance. J Cancer. 2020;11:2962-2971 pubmed publisher |
| Gou W, Li Z, Xu X, Shen J, Guo M, Zhou X, et al. ZX-29, a novel ALK inhibitor, induces apoptosis via ER stress in ALK rearrangement NSCLC cells and overcomes cell resistance caused by an ALK mutation. Biochim Biophys Acta Mol Cell Res. 2020;1867:118712 pubmed publisher |
| Liu X, Zhang Y, Wu S, Xu M, Shen Y, Yu M, et al. Palmatine induces G2/M phase arrest and mitochondrial-associated pathway apoptosis in colon cancer cells by targeting AURKA. Biochem Pharmacol. 2020;175:113933 pubmed publisher |
| Luo J, Yang C, Luo X, Yang Y, Li J, Song B, et al. Chlorogenic acid attenuates cyclophosphamide-induced rat interstitial cystitis. Life Sci. 2020;254:117590 pubmed publisher |
| Du J, Li J, Gao M, Guan Q, Liu T, Wu Y, et al. MAY, a novel tubulin inhibitor, induces cell apoptosis in A549 and A549/Taxol cells and inhibits epithelial-mesenchymal transition in A549/Taxol cells. Chem Biol Interact. 2020;323:109074 pubmed publisher |
| Su W, Zhao J, Fan T. Dose- and Time-Dependent Cytotoxicity of Carteolol in Corneal Endothelial Cells and the Underlying Mechanisms. Front Pharmacol. 2020;11:202 pubmed publisher |
| Deng X, Liu J, Liu L, Sun X, Huang J, Dong J. Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway. Int J Biol Sci. 2020;16:1403-1416 pubmed publisher |
| Xu F, Xu Y, Xiong J, Zhang J, Wu J, Luo J, et al. AOC1 Contributes to Tumor Progression by Promoting the AKT and EMT Pathways in Gastric Cancer. Cancer Manag Res. 2020;12:1789-1798 pubmed publisher |
| Ma L, Sun Y, Li D, Li H, Jin X, Ren D. Overexpressed ITGA2 contributes to paclitaxel resistance by ovarian cancer cells through the activation of the AKT/FoxO1 pathway. Aging (Albany NY). 2020;12:5336-5351 pubmed publisher |
| Cui G, Li L, Xu W, Wang M, Jiao D, Yao B, et al. Astaxanthin Protects Ochratoxin A-Induced Oxidative Stress and Apoptosis in the Heart via the Nrf2 Pathway. Oxid Med Cell Longev. 2020;2020:7639109 pubmed publisher |
| Luan Y, Cui K, Tang Z, Ruan Y, Liu K, Wang T, et al. Human Tissue Kallikrein 1 Improves Erectile Dysfunction of Streptozotocin-Induced Diabetic Rats by Inhibition of Excessive Oxidative Stress and Activation of the PI3K/AKT/eNOS Pathway. Oxid Med Cell Longev. 2020;2020:6834236 pubmed publisher |
| Pan H, Liu F, Wang J, Zhao M, Wang D, Jia C, et al. Dihydromethysticin, a natural molecule from Kava, suppresses the growth of colorectal cancer via the NLRC3/PI3K pathway. Mol Carcinog. 2020;59:575-589 pubmed publisher |
| Zhu X, Feng J, Fu W, Shu X, Wan X, Liu J. Effects of cisplatin on the proliferation, invasion and apoptosis of breast cancer cells following β‑catenin silencing. Int J Mol Med. 2020;45:1838-1850 pubmed publisher |
| Lin H, HAN H, Wang Y, He D, Sun W, Feng L, et al. Shikonin and 4-hydroxytamoxifen synergistically inhibit the proliferation of breast cancer cells through activating apoptosis signaling pathway in vitro and in vivo. Chin Med. 2020;15:23 pubmed publisher |
| Zhang X, Wang Y, Tong J, Ning X, Zhou F, Yang X, et al. Pyruvate alleviates high glucose-induced endoplasmic reticulum stress and apoptosis in HK-2 cells. FEBS Open Bio. 2020;10:827-834 pubmed publisher |
| Liu H, Liu Z, Gao M, Hu X, Sun R, Shen X, et al. The Effects of Daxx Knockout on Pluripotency and Differentiation of Mouse Induced Pluripotent Stem Cells. Cell Reprogram. 2020;22:90-98 pubmed publisher |
| Gao L, Qian B, Chen H, Wang A, Li Q, Li J, et al. Hic-5 deficiency attenuates hepatic ischemia reperfusion injury through TLR4/NF-κB signaling pathways. Life Sci. 2020;249:117517 pubmed publisher |
| Zhang N, Zhang Y, Qian H, Wu S, Cao L, Sun Y. Selective targeting of ubiquitination and degradation of PARP1 by E3 ubiquitin ligase WWP2 regulates isoproterenol-induced cardiac remodeling. Cell Death Differ. 2020;27:2605-2619 pubmed publisher |
| Feng A, Han X, Meng X, Chen Z, Li Q, Shu W, et al. PRDX2 plays an oncogenic role in esophageal squamous cell carcinoma via Wnt/β-catenin and AKT pathways. Clin Transl Oncol. 2020;22:1838-1848 pubmed publisher |
| Liu A, Zuo Z, Liu L, Liu L. Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer. Biochem Cell Biol. 2020;:1-8 pubmed publisher |
| Xiong Y, Yin Q, Li J, He S. Oxidative Stress and Endoplasmic Reticulum Stress Are Involved in the Protective Effect of Alpha Lipoic Acid Against Heat Damage in Chicken Testes. Animals (Basel). 2020;10: pubmed publisher |
| Yu X, Li H, Zhu M, Hu P, Liu X, Qing Y, et al. Involvement of p53 Acetylation in Growth Suppression of Cutaneous T-Cell Lymphomas Induced by HDAC Inhibition. J Invest Dermatol. 2020;: pubmed publisher |
| Tang B, Tang M, Xu Q, Guo J, Xuan L, Zhou J, et al. MicroRNA-143-5p modulates pulmonary artery smooth muscle cells functions in hypoxic pulmonary hypertension through targeting HIF-1α. J Biosci. 2020;45: pubmed |
| Xu B, Zang S, Lang L, Lian S, Lu J, Li S, et al. Down-regulation of miR-383-5p suppresses apoptosis in oxidative stress rat hepatocytes by targeting Bcl2. J Anim Physiol Anim Nutr (Berl). 2020;: pubmed publisher |
| Fan J, Ren D, Wang J, Liu X, Zhang H, Wu M, et al. Bruceine D induces lung cancer cell apoptosis and autophagy via the ROS/MAPK signaling pathway in vitro and in vivo. Cell Death Dis. 2020;11:126 pubmed publisher |
| Zhang J, Wang Y, Ju M, Song J, Zheng Y, Lin S, et al. Neuroprotective Effect of the Inhibitor Salubrinal after Cardiac Arrest in a Rodent Model. Oxid Med Cell Longev. 2020;2020:7468738 pubmed publisher |
| Zhou L, Yang C, Zhang N, Zhang X, Zhao T, Yu J. Silencing METTL3 inhibits the proliferation and invasion of osteosarcoma by regulating ATAD2. Biomed Pharmacother. 2020;125:109964 pubmed publisher |
| Bronowicka Adamska P, Bentke A, Lasota M, Wróbel M. Effect of S-Allyl -L-Cysteine on MCF-7 Cell Line 3-Mercaptopyruvate Sulfurtransferase/Sulfane Sulfur System, Viability and Apoptosis. Int J Mol Sci. 2020;21: pubmed publisher |
| Wu K, Li L, Li L, Wang D. Long non-coding RNA HAL suppresses the migration and invasion of serous ovarian cancer by inhibiting EMT signaling pathway. Biosci Rep. 2020;40: pubmed publisher |
| Man S, Yang L, Xiang H, Lu G, Wang Y, Liu C, et al. Antihypertensive and renal protective effect of Shunaoxin pill combined with captopril on spontaneous hypertension rats. Biomed Pharmacother. 2020;125:109977 pubmed publisher |
| Shang Y, Wang Q, Li J, Zhao Q, Huang X, Dong H, et al. The Acetone Indigo Red Dehydrating Agent IF203 Induces HepG2 Cell Death Through Cell Cycle Arrest, Autophagy and Apoptosis. Onco Targets Ther. 2020;13:473-486 pubmed publisher |
| Qi W, Li Z, Yang C, Jiangshan Dai J, Zhang Q, Wang D, et al. Inhibitory mechanism of muscone in liver cancer involves the induction of apoptosis and autophagy. Oncol Rep. 2020;43:839-850 pubmed publisher |
| Yu M, Zeng M, Pan Z, Wu F, Guo L, He G. Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells. Eur J Med Chem. 2020;189:112076 pubmed publisher |
| Feng J, Dai W, Mao Y, Wu L, Li J, Chen K, et al. Simvastatin re-sensitizes hepatocellular carcinoma cells to sorafenib by inhibiting HIF-1α/PPAR-γ/PKM2-mediated glycolysis. J Exp Clin Cancer Res. 2020;39:24 pubmed publisher |
| He H, Xu C, Zheng L, Wang K, Jin M, Sun Y, et al. Polyphyllin VII induces apoptotic cell death via inhibition of the PI3K/Akt and NF‑κB pathways in A549 human lung cancer cells. Mol Med Rep. 2020;21:597-606 pubmed publisher |
| Li C, Zhou J, Liu Z, Zhou J, Yao W, Tao J, et al. FSH prevents porcine granulosa cells from hypoxia-induced apoptosis via activating mitophagy through the HIF-1α-PINK1-Parkin pathway. FASEB J. 2020;34:3631-3645 pubmed publisher |
| He X, Chen S, Li C, Ban J, Wei Y, He Y, et al. Trehalose Alleviates Crystalline Silica-Induced Pulmonary Fibrosis via Activation of the TFEB-Mediated Autophagy-Lysosomal System in Alveolar Macrophages. Cells. 2020;9: pubmed publisher |
| Kong F, Zou H, Liu X, He J, Zheng Y, Xiong L, et al. miR-7112-3p targets PERK to regulate the endoplasmic reticulum stress pathway and apoptosis induced by photodynamic therapy in colorectal cancer CX-1 cells. Photodiagnosis Photodyn Ther. 2020;29:101663 pubmed publisher |
| Lv S, Ju C, Peng J, Liang M, Zhu F, Wang C, et al. 25-Hydroxycholesterol protects against myocardial ischemia-reperfusion injury via inhibiting PARP activity. Int J Biol Sci. 2020;16:298-308 pubmed publisher |
| Gucer H, Caliskan S, Kefeli M, Mete O. Do You Know the Details of Your PAX8 Antibody? Monoclonal PAX8 (MRQ-50) Is Not Expressed in a Series of 45 Medullary Thyroid Carcinomas. Endocr Pathol. 2020;: pubmed publisher |
| Shopit A, Niu M, Wang H, Tang Z, Li X, Tesfaldet T, et al. Protection of diabetes-induced kidney injury by phosphocreatine via the regulation of ERK/Nrf2/HO-1 signaling pathway. Life Sci. 2020;242:117248 pubmed publisher |
| Wu J, He J, Tian X, Zhong J, Li H, Sun X. Activation of the Hedgehog Pathway Promotes Recovery of Neurological Function After Traumatic Brain Injury by Protecting the Neurovascular Unit. Transl Stroke Res. 2020;: pubmed publisher |
| Zhang L, Yan X, Yu S, Zhong X, Tian R, Xu L, et al. LINC00365-SCGB2A1 axis inhibits the viability of breast cancer through targeting NF-κB signaling. Oncol Lett. 2020;19:753-762 pubmed publisher |
| Liu Q, Zhao M, Chen W, Xu K, Huang F, Qu J, et al. Mainstream cigarette smoke induces autophagy and promotes apoptosis in oral mucosal epithelial cells. Arch Oral Biol. 2020;111:104646 pubmed publisher |
| Xu S, Wang Y, Yu M, Wang D, Liang Y, Chen Y, et al. LongShengZhi capsule inhibits doxorubicin-induced heart failure by anti-oxidative stress. Biomed Pharmacother. 2020;123:109803 pubmed publisher |
| Wang J, Xu H, Cheng X, Yang J, Yan Z, Ma H, et al. Calcium relieves fluoride-induced bone damage through the PI3K/AKT pathway. Food Funct. 2020;11:1155-1164 pubmed publisher |
| Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B. 1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway. Biochem Pharmacol. 2020;172:113752 pubmed publisher |
| Li S, Xie Y, Yang B, Huang S, Zhang Y, Jia Z, et al. MicroRNA-214 targets COX-2 to antagonize indoxyl sulfate (IS)-induced endothelial cell apoptosis. Apoptosis. 2020;25:92-104 pubmed publisher |
| Li C, Xia M, Wang H, Li W, Peng J, Jiang H. Propofol facilitates migration and invasion of oral squamous cell carcinoma cells by upregulating SNAI1 expression. Life Sci. 2020;241:117143 pubmed publisher |
| Zhang K, Bai Y, Xu R, Li J, Guan F. The mechanism of PDA/PEI/5-Fu coated esophageal stent material on inhibiting cancer associated pathological cells. J Biomed Mater Res A. 2020;108:814-821 pubmed publisher |
| Li X, Yao Z, Yang D, Jiang X, Sun J, Tian L, et al. Cyanidin-3-O-glucoside restores spermatogenic dysfunction in cadmium-exposed pubertal mice via histone ubiquitination and mitigating oxidative damage. J Hazard Mater. 2020;387:121706 pubmed publisher |
| Zhang W, Zhu T, Chen L, Luo W, Chao J. MCP-1 mediates ischemia-reperfusion-induced cardiomyocyte apoptosis via MCPIP1 and CaSR. Am J Physiol Heart Circ Physiol. 2020;318:H59-H71 pubmed publisher |
| Zheng Y, Nie P, Xu S. Long noncoding RNA CASC21 exerts an oncogenic role in colorectal cancer through regulating miR-7-5p/YAP1 axis. Biomed Pharmacother. 2020;121:109628 pubmed publisher |
| Liu Q, Zhang S, Zhu D, Tang X, Che Y, Feng X. The parthenolide derivative ACT001 synergizes with low doses of L-DOPA to improve MPTP-induced Parkinson's disease in mice. Behav Brain Res. 2020;379:112337 pubmed publisher |
| Hua W, Li S, Luo R, Wu X, Zhang Y, Liao Z, et al. Icariin protects human nucleus pulposus cells from hydrogen peroxide-induced mitochondria-mediated apoptosis by activating nuclear factor erythroid 2-related factor 2. Biochim Biophys Acta Mol Basis Dis. 2020;1866:165575 pubmed publisher |
| Liang L, Wang M, Liu M, Zhao W, Wang X, Shi L, et al. Chronic toxicity of methamphetamine: Oxidative remodeling of pulmonary arteries. Toxicol In Vitro. 2020;62:104668 pubmed publisher |
| Jin W, Zhang Y, Xue Y, Han X, Zhang X, Ma Z, et al. Crocin attenuates isoprenaline-induced myocardial fibrosis by targeting TLR4/NF-κB signaling: connecting oxidative stress, inflammation, and apoptosis. Naunyn Schmiedebergs Arch Pharmacol. 2020;393:13-23 pubmed publisher |
| Shi S, Zheng G, Yang C, Chen X, Yan Q, Jiang F, et al. Effects of Vitamin K3 Combined with UVB on the Proliferation and Apoptosis of Cutaneous Squamous Cell Carcinoma A431 Cells. Onco Targets Ther. 2019;12:11715-11727 pubmed publisher |
| Huang H, Cao K, Kong Y, Yuan S, Liu H, Wang Y, et al. A dual functional ruthenium arene complex induces differentiation and apoptosis of acute promyelocytic leukemia cells. Chem Sci. 2019;10:9721-9728 pubmed publisher |
| Kong D, Li A, Liu Y, Cui Q, Wang K, Zhang D, et al. SIX1 Activates STAT3 Signaling to Promote the Proliferation of Thyroid Carcinoma via EYA1. Front Oncol. 2019;9:1450 pubmed publisher |
| Lin X, Zhu J, Ni H, Rui Q, Sha W, Yang H, et al. Treatment With 2-BFI Attenuated Spinal Cord Injury by Inhibiting Oxidative Stress and Neuronal Apoptosis via the Nrf2 Signaling Pathway. Front Cell Neurosci. 2019;13:567 pubmed publisher |
| Zhang C, Wang B, Wang X, Sheng X, Cui Y. Sevoflurane inhibits the progression of ovarian cancer through down-regulating stanniocalcin 1 (STC1). Cancer Cell Int. 2019;19:339 pubmed publisher |
| Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, et al. Phosphocreatine Improves Cardiac Dysfunction by Normalizing Mitochondrial Respiratory Function through JAK2/STAT3 Signaling Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:6521218 pubmed publisher |
| Sun B, Luo X, Yang C, Liu P, Yang Y, Dong X, et al. Therapeutic Effects of Human Urine-Derived Stem Cells in a Rat Model of Cisplatin-Induced Acute Kidney Injury In Vivo and In Vitro. Stem Cells Int. 2019;2019:8035076 pubmed publisher |
| Assani G, Segbo J, Yu X, Yessoufou A, Xiong Y, Zhou F, et al. Downregulation of TMPRSS4 Enhances Triple-Negative Breast Cancer Cell Radiosensitivity Through Cell Cycle and Cell Apoptosis Process Impairment. Asian Pac J Cancer Prev. 2019;20:3679-3687 pubmed publisher |
| Chen L, Wu X, Zeb F, Huang Y, An J, Jiang P, et al. Acrolein-induced apoptosis of smooth muscle cells through NEAT1-Bmal1/Clock pathway and a protection from asparagus extract. Environ Pollut. 2019;258:113735 pubmed publisher |
| Zeng Q, He S, Zhong L, Wang L, Cheng F, Zhang H, et al. [Exogenous hydrogen sulfide improves erectile dysfunction by inhibiting apoptosis of corpus cavernosum smooth muscle cells in rats with cavernous nerve injury]. Nan Fang Yi Ke Da Xue Xue Bao. 2019;39:1329-1336 pubmed publisher |
| Zhu H, Shao Y, Qin L, Wang J, Feng S, Jiang Y, et al. Catalpol Enhances Neurogenesis And Inhibits Apoptosis Of New Neurons Via BDNF, But Not The BDNF/Trkb Pathway. Drug Des Devel Ther. 2019;13:4145-4157 pubmed publisher |
| Liu H, Kai L, Du H, Wang X, Wang Y. LPS Inhibits Fatty Acid Absorption in Enterocytes through TNF-α Secreted by Macrophages. Cells. 2019;8: pubmed publisher |
| Li Y, Wang C, Lu J, Huang K, Han Y, Chen J, et al. PPAR δ inhibition protects against palmitic acid-LPS induced lipidosis and injury in cultured hepatocyte L02 cell. Int J Med Sci. 2019;16:1593-1603 pubmed publisher |
| Li Y, Chen H, Yang Y, Niu M, Wang J, Wu Y, et al. Danshen formula granule and salvianic acid A alleviate ethanol-induced neurotoxicity. J Nat Med. 2019;: pubmed publisher |
| Du Y, Qian B, Gao L, Tan P, Chen H, Wang A, et al. Aloin Preconditioning Attenuates Hepatic Ischemia/Reperfusion Injury via Inhibiting TLR4/MyD88/NF-κB Signal Pathway In Vivo and In Vitro. Oxid Med Cell Longev. 2019;2019:3765898 pubmed publisher |
| Sun Y, Gong J, Cao Y. Multi-Walled Carbon Nanotubes (MWCNTs) Activate Apoptotic Pathway Through ER Stress: Does Surface Chemistry Matter?. Int J Nanomedicine. 2019;14:9285-9294 pubmed publisher |
| Gong C, Ai J, Fan Y, Gao J, Liu W, Feng Q, et al. NCAPG Promotes The Proliferation Of Hepatocellular Carcinoma Through PI3K/AKT Signaling. Onco Targets Ther. 2019;12:8537-8552 pubmed publisher |
| Yang D, Yu J, Liu H, Yan X, Hu J, Yu Y, et al. The long non-coding RNA TUG1-miR-9a-5p axis contributes to ischemic injuries by promoting cardiomyocyte apoptosis via targeting KLF5. Cell Death Dis. 2019;10:908 pubmed publisher |
| Sun K, Luo J, Jing X, Guo J, Yao X, Hao X, et al. Astaxanthin protects against osteoarthritis via Nrf2: a guardian of cartilage homeostasis. Aging (Albany NY). 2019;11:10513-10531 pubmed publisher |
| Wang H, Peng X, Huang Y, Xiao Y, Wang Z, Zhan L. Propofol Attenuates Hypoxia/Reoxygenation-Induced Apoptosis and Autophagy in HK-2 Cells by Inhibiting JNK Activation. Yonsei Med J. 2019;60:1195-1202 pubmed publisher |
| Hua S, Liu J, Zhang Y, Li J, Zhang X, Dong L, et al. Piperine as a neuroprotective functional component in rats with cerebral ischemic injury. Food Sci Nutr. 2019;7:3443-3451 pubmed publisher |
| Peng Y, Wang L, Wu L, Zhang L, Nie G, Guo M. Methylation of SLFN11 promotes gastric cancer growth and increases gastric cancer cell resistance to cisplatin. J Cancer. 2019;10:6124-6134 pubmed publisher |
| Tian N, Shangguan W, Zhou Z, Yao Y, Fan C, Cai L. Lin28b is involved in curcumin-reversed paclitaxel chemoresistance and associated with poor prognosis in hepatocellular carcinoma. J Cancer. 2019;10:6074-6087 pubmed publisher |
| Xu W, Zheng H, Yang R, Liu T, Yu W, Zheng X, et al. Mitochondrial NDUFA4L2 attenuates the apoptosis of nucleus pulposus cells induced by oxidative stress via the inhibition of mitophagy. Exp Mol Med. 2019;51:140 pubmed publisher |
| Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, et al. FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival. Cell Death Dis. 2019;10:872 pubmed publisher |
| Jiang J, Wang X, Gao G, Liu X, Chang H, Xiong R, et al. Silencing of lncRNA HOXA11-AS inhibits cell migration, invasion, proliferation, and promotes apoptosis in human glioma cells via upregulating microRNA-125a: in vitro and in vivo studies. Am J Transl Res. 2019;11:6382-6392 pubmed |
| Liu L, Chen H, Jin J, Tang Z, Yin P, Zhong D, et al. Melatonin ameliorates cerebral ischemia/reperfusion injury through SIRT3 activation. Life Sci. 2019;239:117036 pubmed publisher |
| Luo X, Wu X, Wei X, Wang A, Wang S, Wang J. LncRNA ADPGK-AS1 regulated cell proliferation, invasion, migration and apoptosis via targeting miR-542-3p in osteosarcoma. Eur Rev Med Pharmacol Sci. 2019;23:8751-8760 pubmed publisher |
| Wang Y, Cao P, Alshwmi M, Jiang N, Xiao Z, Jiang F, et al. GPX2 suppression of H2O2 stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway. Onco Targets Ther. 2019;12:6639-6651 pubmed publisher |
| Li H, Chen W, Chen Y, Zhou Q, Xiao P, Tang R, et al. Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression. Front Pharmacol. 2019;10:1197 pubmed publisher |
| Shangguan W, Lv X, Tian N. FoxD2-AS1 is a prognostic factor in glioma and promotes temozolomide resistance in a O6-methylguanine-DNA methyltransferase-dependent manner. Korean J Physiol Pharmacol. 2019;23:475-482 pubmed publisher |
| Guo X, Shi Y, Du P, Wang J, Han Y, Sun B, et al. HMGB1/TLR4 promotes apoptosis and reduces autophagy of hippocampal neurons in diabetes combined with OSA. Life Sci. 2019;239:117020 pubmed publisher |
| Xu Y, Ou N, Song Y, Wang X, Kang J, Yang Y, et al. Seminal plasma miR-210-3p induces spermatogenic cell apoptosis by activating caspase-3 in patients with varicocele. Asian J Androl. 2019;: pubmed publisher |
| Zhu J, Liu B, Wang Z, Wang D, Ni H, Zhang L, et al. Exosomes from nicotine-stimulated macrophages accelerate atherosclerosis through miR-21-3p/PTEN-mediated VSMC migration and proliferation. Theranostics. 2019;9:6901-6919 pubmed publisher |
| Zhu Y, Yu F, Tan Y, Hong Y, Meng T, Liu Y, et al. Reversing activity of cancer associated fibroblast for staged glycolipid micelles against internal breast tumor cells. Theranostics. 2019;9:6764-6779 pubmed publisher |
| Peng F, Zhang N, Wang C, Wang X, Huang W, Peng C, et al. Aconitine induces cardiomyocyte damage by mitigating BNIP3-dependent mitophagy and the TNFα-NLRP3 signalling axis. Cell Prolif. 2019;:e12701 pubmed publisher |
| Zhang J, Yao D, Song Y, Pan Y, Zhu L, Bai Y, et al. Fractionated irradiation of right thorax induces abscopal damage on testes leading to decline in fertility. Sci Rep. 2019;9:15221 pubmed publisher |
| Zhang Y, Xie H, Tang W, Zeng X, Lin Y, Xu L, et al. Trichostatin A, a Histone Deacetylase Inhibitor, Alleviates Eosinophilic Meningitis Induced by Angiostrongylus cantonensis Infection in Mice. Front Microbiol. 2019;10:2280 pubmed publisher |
| Ren M, Gu M, Zhou X, Yu M, Pan H, Ji F, et al. Sirtuin 1 alleviates endoplasmic reticulum stress-mediated apoptosis of intestinal epithelial cells in ulcerative colitis. World J Gastroenterol. 2019;25:5800-5813 pubmed publisher |
| Nie X, Xia F, Liu Y, Zhou Y, Ye W, Hean P, et al. Downregulation of Wnt3 Suppresses Colorectal Cancer Development Through Inhibiting Cell Proliferation and Migration. Front Pharmacol. 2019;10:1110 pubmed publisher |
| Wang S, Hu H, Zhong B, Shi D, Qing X, Cheng C, et al. Bruceine D inhibits tumor growth and stem cell-like traits of osteosarcoma through inhibition of STAT3 signaling pathway. Cancer Med. 2019;8:7345-7358 pubmed publisher |
| Yuan S, Xu Y, Wang C, An H, Xu H, Li K, et al. Doxorubicin-polyglycerol-nanodiamond conjugate is a cytostatic agent that evades chemoresistance and reverses cancer-induced immunosuppression in triple-negative breast cancer. J Nanobiotechnology. 2019;17:110 pubmed publisher |
| Xu B, Lang L, Lian S, Guo J, Wang J, Yang H, et al. Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure. Brain Sci. 2019;9: pubmed publisher |
| Xu F, Yan J, Gan Y, Chang Y, Wang H, He X, et al. miR-885-5p Negatively Regulates Warburg Effect by Silencing Hexokinase 2 in Liver Cancer. Mol Ther Nucleic Acids. 2019;18:308-319 pubmed publisher |
| Zhang P, He D, Song E, Jiang M, Song Y. Celecoxib enhances the sensitivity of non-small-cell lung cancer cells to radiation-induced apoptosis through downregulation of the Akt/mTOR signaling pathway and COX-2 expression. PLoS ONE. 2019;14:e0223760 pubmed publisher |
| Xu R, Li Y, Yan H, Zhang E, Huang X, Chen Q, et al. CCL2 promotes macrophages-associated chemoresistance via MCPIP1 dual catalytic activities in multiple myeloma. Cell Death Dis. 2019;10:781 pubmed publisher |
| Wu Y, Li Z, Zhang L, Liu G. Tivantinib Hampers the Proliferation of Glioblastoma Cells via PI3K/Akt/Mammalian Target of Rapamycin (mTOR) Signaling. Med Sci Monit. 2019;25:7383-7390 pubmed publisher |
| Li J, Bao G, ALyafeai E, Ding J, Li S, Sheng S, et al. Betulinic Acid Enhances the Viability of Random-Pattern Skin Flaps by Activating Autophagy. Front Pharmacol. 2019;10:1017 pubmed publisher |
| Mo D, Tian W, Zhang H, Feng Y, Sun Y, Quan W, et al. Cardioprotective effects of galectin-3 inhibition against ischemia/reperfusion injury. Eur J Pharmacol. 2019;863:172701 pubmed publisher |
| He F, Dai R, Zhou X, Li X, Song X, Yan H, et al. Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed publisher |
| Li M, Hao S, Li C, Xiao H, Sun L, Yu Z, et al. Elevated SH3BP5 Correlates with Poor Outcome and Contributes to the Growth of Acute Myeloid Leukemia Cells. Biomolecules. 2019;9: pubmed publisher |
| Shu W, Liu G, Dai Y, Feng A, Chen Z, Han J, et al. The oncogenic role of NKAP in the growth and invasion of colon cancer cells. Oncol Rep. 2019;42:2130-2138 pubmed publisher |
| Jing L, Jiang J, Liu D, Sheng J, Zhang W, Li Z, et al. Structural Characterization and Antioxidant Activity of Polysaccharides from Athyrium multidentatum (Doll.) Ching in d-Galactose-Induced Aging Mice via PI3K/AKT Pathway. Molecules. 2019;24: pubmed publisher |
| Ye M, Ma J, Liu B, Liu X, Ma D, Dong K. Linc01105 acts as an oncogene in the development of neuroblastoma. Oncol Rep. 2019;: pubmed publisher |
| Zeng N, Zhang Z, Jiang H, Li R, Chang C, Wang F, et al. LncRNA-241 inhibits 1,2-Dichloroethane-induced hepatic apoptosis. Toxicol In Vitro. 2019;61:104650 pubmed publisher |
| Guo Z, Tian Y, Guo Y, Li B, Liu X, Xie K, et al. RAD6B Plays a Critical Role in Neuronal DNA Damage Response to Resist Neurodegeneration. Front Cell Neurosci. 2019;13:392 pubmed publisher |
| Wang K, Tu Y, Wan J, Chen M, He C. Synergistic anti-breast cancer effect of pulsatilla saponin D and camptothecin through interrupting autophagic-lysosomal function and promoting p62-mediated ubiquitinated protein aggregation. Carcinogenesis. 2019;: pubmed publisher |
| Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, et al. MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer. Aging (Albany NY). 2019;11:6734-6761 pubmed publisher |
| Qian Y, Xie Y, Wang C, Shi Z, Jiang C, Tang Y, et al. Mkrn2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis. Asian J Androl. 2019;: pubmed publisher |
| Wang J, Shao L, Rao T, Zhang W, Huang W. Chemo-Preventive Potential of Falcarindiol-Enriched Fraction from Oplopanax elatus on Colorectal Cancer Interfered by Human Gut Microbiota. Am J Chin Med. 2019;47:1381-1404 pubmed publisher |
| Wen N, Guo B, Zheng H, Xu L, Liang H, Wang Q, et al. Bromodomain inhibitor jq1 induces cell cycle arrest and apoptosis of glioma stem cells through the VEGF/PI3K/AKT signaling pathway. Int J Oncol. 2019;55:879-895 pubmed publisher |
| Shaoyong W, Li Q, Ren Z, Xiao J, Diao Z, Yang G, et al. Effects of kojic acid on boar sperm quality and anti-bacterial activity during liquid preservation at 17 C. Theriogenology. 2019;140:124-135 pubmed publisher |
| Li C, Hu W, Lu M, Xiao G. Resveratrol induces apoptosis of benign prostatic hyperplasia epithelial cell line (BPH-1) through p38 MAPK-FOXO3a pathway. BMC Complement Altern Med. 2019;19:233 pubmed publisher |
| Yang Q, Wang C, Jin Y, Ma X, Xie T, Wang J, et al. Disocin prevents postmenopausal atherosclerosis in ovariectomized LDLR-/- mice through a PGC-1α/ERα pathway leading to promotion of autophagy and inhibition of oxidative stress, inflammation and apoptosis. Pharmacol Res. 2019;148:104414 pubmed publisher |
| Zhi F, Zhou D, Bai F, Li J, Xiang C, Zhang G, et al. VceC Mediated IRE1 Pathway and Inhibited CHOP-induced Apoptosis to Support Brucella Replication in Goat Trophoblast Cells. Int J Mol Sci. 2019;20: pubmed publisher |
| Gong D, Wang L, Yang Y, Zhang J, Liu X. Diabetes aggravates renal ischemia and reperfusion injury in rats by exacerbating oxidative stress, inflammation, and apoptosis. Ren Fail. 2019;41:750-761 pubmed publisher |
| Zhu C, Huang Q. Overexpression of the SMYD3 Promotes Proliferation, Migration, and Invasion of Pancreatic Cancer. Dig Dis Sci. 2019;: pubmed publisher |
| Zhang M, Wang X, Guo F, Jia Q, Liu N, Chen Y, et al. Cdc42 Deficiency Leads To Epidermal Barrier Dysfunction by Regulating Intercellular Junctions and Keratinization of Epidermal Cells during Mouse Skin Development. Theranostics. 2019;9:5065-5084 pubmed publisher |
| Chen L, Tian Q, Wang W. Association between CIRP expression and hypoxic-ischemic brain injury in neonatal rats. Exp Ther Med. 2019;18:1515-1520 pubmed publisher |
| Zhu L, Xia C, Wu L, Zhang Y, Liu J, Chen Y, et al. The critical role of RasGRP4 in the growth of diffuse large B cell lymphoma. Cell Commun Signal. 2019;17:92 pubmed publisher |
| Liu Y, Chen H, Zhang L, Zhang T, Ren X. The Association Between Thyroid Injury and Apoptosis, and Alterations of Bax, Bcl-2, and Caspase-3 mRNA/Protein Expression Induced by Nickel Sulfate in Wistar Rats. Biol Trace Elem Res. 2019;: pubmed publisher |
| Ming Yan Y, Jing Z, Shu Qin G, Xiao Liang B, Zhi Hong L, Xue Z. Liraglutide inhibits the apoptosis of human nucleus pulposus cells induced by high glucose through PI3K/Akt/caspase-3 signaling pathway. Biosci Rep. 2019;39: pubmed publisher |
| Li M, Chen C, Zhang W, Gao R, Wang Q, Chen H, et al. Identification of the Potential Key Long Non-coding RNAs in Aged Mice With Postoperative Cognitive Dysfunction. Front Aging Neurosci. 2019;11:181 pubmed publisher |
| Liu A, Xu X, Hou R, Badawy S, Tao Y, Chen D, et al. DNA methylation and RASSF4 expression are involved in T-2 toxin-induced hepatotoxicity. Toxicology. 2019;425:152246 pubmed publisher |
| Cao T, Xu R, Xu Y, Liu Y, Qi D, Wan Q. The protective effect of Cordycepin on diabetic nephropathy through autophagy induction in vivo and in vitro. Int Urol Nephrol. 2019;: pubmed publisher |
| Wang H, He Y, Cheng D, Pu D, Tan R, Gao L, et al. Cypermethrin exposure reduces the ovarian reserve by causing mitochondrial dysfunction in granulosa cells. Toxicol Appl Pharmacol. 2019;379:114693 pubmed publisher |
| Wang Y, Wu J, Li Y, Qi X. Polysaccharides of Fructus corni Improve Ovarian Function in Mice with Aging-Associated Perimenopause Symptoms. Evid Based Complement Alternat Med. 2019;2019:2089586 pubmed publisher |
| Zhang Q, Cao W, Wang X, Zhang M, Lu X, Chen J, et al. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Phytother Res. 2019;: pubmed publisher |
| Zhang R, Wang C, Tian Y, Yao Y, Mao J, Wang H, et al. SIRT5 Promotes Hepatocellular Carcinoma Progression by Regulating Mitochondrial Apoptosis. J Cancer. 2019;10:3871-3882 pubmed publisher |
| Liao X, Fan Y, Hou J, Chen X, Xu X, Yang Y, et al. Identification of Chaetocin as a Potent non-ROS-mediated Anticancer Drug Candidate for Gastric Cancer. J Cancer. 2019;10:3678-3690 pubmed publisher |
| Zhang T, Chen H, Cao J, Xiong H, Mo X, Li T, et al. Structural and functional analyses of hepatitis B virus X protein BH3-like domain and Bcl-xL interaction. Nat Commun. 2019;10:3192 pubmed publisher |
| Deng L, Sun J, Chen X, Liu L, Wu D. Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma. J Exp Clin Cancer Res. 2019;38:316 pubmed publisher |
| Wang W, Wu L, Li J, Ji J, Chen K, Yu Q, et al. Alleviation of Hepatic Ischemia Reperfusion Injury by Oleanolic Acid Pretreating via Reducing HMGB1 Release and Inhibiting Apoptosis and Autophagy. Mediators Inflamm. 2019;2019:3240713 pubmed publisher |
| Li X, Zhang T, Kamara M, Lu G, Xu H, Wang D, et al. Discovery of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido) phenylurea-based thymidylate synthase (TS) inhibitor as a novel multi-effects antitumor drugs with minimal toxicity. Cell Death Dis. 2019;10:532 pubmed publisher |
| Shang Y, Wang Q, Wu B, Zhao Q, Li J, Huang X, et al. Platelet-Membrane-Camouflaged Black Phosphorus Quantum Dots Enhance Anticancer Effect Mediated by Apoptosis and Autophagy. ACS Appl Mater Interfaces. 2019;11:28254-28266 pubmed publisher |
| Zhang Y, Zhang X, Wei Q, Leng S, Li C, Han B, et al. Activation of Sigma-1 Receptor Enhanced Pericyte Survival via the Interplay Between Apoptosis and Autophagy: Implications for Blood-Brain Barrier Integrity in Stroke. Transl Stroke Res. 2019;: pubmed publisher |
| Liao Z, Luo R, Li G, Song Y, Zhan S, Zhao K, et al. Exosomes from mesenchymal stem cells modulate endoplasmic reticulum stress to protect against nucleus pulposus cell death and ameliorate intervertebral disc degeneration in vivo. Theranostics. 2019;9:4084-4100 pubmed publisher |
| Ye J, Xue M, Liu Y, Zhu S, Li Y, Liu X, et al. Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy. Front Pharmacol. 2019;10:676 pubmed publisher |
| Li X, Zhang N, Zhang Y, Jia P, Guo Y, Tian Y, et al. E3 ligase Fbw7 participates in oxidative stress‑induced myocardial cell injury via interacting with Mcl‑1. Mol Med Rep. 2019;20:1561-1568 pubmed publisher |
| Khan M, Zhao P, Khan A, Raza F, Raza S, Sarfraz M, et al. Synergism of cisplatin-oleanolic acid co-loaded calcium carbonate nanoparticles on hepatocellular carcinoma cells for enhanced apoptosis and reduced hepatotoxicity. Int J Nanomedicine. 2019;14:3753-3771 pubmed publisher |
| Xu W, Yang R, Zheng H, Yu W, Zheng X, Li B, et al. PGC-1α acts as an mediator of Sirtuin2 to protect annulus fibrosus from apoptosis induced by oxidative stress through restraining mitophagy. Int J Biol Macromol. 2019;136:1007-1017 pubmed publisher |
| Dijiong W, Xiaowen W, Linlong X, Wenbin L, Huijin H, Baodong Y, et al. Iron chelation effect of curcumin and baicalein on aplastic anemia mouse model with iron overload. Iran J Basic Med Sci. 2019;22:660-668 pubmed publisher |
| Lin J, Fang L, Li H, Li Z, Lyu L, Wang H, et al. Astragaloside IV alleviates doxorubicin induced cardiomyopathy by inhibiting NADPH oxidase derived oxidative stress. Eur J Pharmacol. 2019;:172490 pubmed publisher |
| Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, et al. Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors. Toxicol Lett. 2019;: pubmed publisher |
| Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, et al. LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury. Neuroscience. 2019;: pubmed publisher |
| Li X, Zhang Y, Chai X, Zhou S, Zhang H, He J, et al. Overexpression of MEF2D contributes to oncogenic malignancy and chemotherapeutic resistance in ovarian carcinoma. Am J Cancer Res. 2019;9:887-905 pubmed |
| Lei Y, Yang Y, Zhao J, Gao H, Chen R, Bai B, et al. P-AKT2/SPK1 (P-SPK1) and P-MEK/P-ERK cell signaling pathways are involved in LPS-induced macrophage migration. Am J Transl Res. 2019;11:2725-2741 pubmed |
| Yan X, Fu X, Jia Y, Ma X, Tao J, Yang T, et al. Nrf2/Keap1/ARE Signaling Mediated an Antioxidative Protection of Human Placental Mesenchymal Stem Cells of Fetal Origin in Alveolar Epithelial Cells. Oxid Med Cell Longev. 2019;2019:2654910 pubmed publisher |
| Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher |
| Huang F, Liang X, Min X, Zhang Y, Wang G, Peng Z, et al. Simultaneous Inhibition of EGFR and HER2 via Afatinib Augments the Radiosensitivity of Nasopharyngeal Carcinoma Cells. J Cancer. 2019;10:2063-2073 pubmed publisher |
| Wu D, Li M, Gao Y, Tian W, Li J, Zhang Q, et al. Peptide V3 Inhibits the Growth of Human Hepatocellular Carcinoma by Inhibiting the Ras/Raf/MEK/ERK Signaling Pathway. J Cancer. 2019;10:1693-1706 pubmed publisher |
| Li N, Guo X, Liu L, Wang L, Cheng R. Molecular mechanism of miR-204 regulates proliferation, apoptosis and autophagy of cervical cancer cells by targeting ATF2. Artif Cells Nanomed Biotechnol. 2019;47:2529-2535 pubmed publisher |
| Wu T, Jiang N, Ji Z, Shi G. The IRE1 signaling pathway is involved in the protective effect of low-dose LPS on myocardial ischemia-reperfusion injury. Life Sci. 2019;:116569 pubmed publisher |
| Cui C, Li Z, Wu D. The long non-coding RNA H19 induces hypoxia/reoxygenation injury by up-regulating autophagy in the hepatoma carcinoma cells. Biol Res. 2019;52:32 pubmed publisher |
| Guo T, Liu T, Sun Y, Liu X, Xiong R, Li H, et al. Sonodynamic therapy inhibits palmitate-induced beta cell dysfunction via PINK1/Parkin-dependent mitophagy. Cell Death Dis. 2019;10:457 pubmed publisher |
| Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, et al. Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy. Pharmacol Res. 2019;146:104308 pubmed publisher |
| Xu S, Ma H, Bo Y, Shao M. The oncogenic role of CB2 in the progression of non-small-cell lung cancer. Biomed Pharmacother. 2019;117:109080 pubmed publisher |
| Liu X, Lu Y, Xu Y, Hou S, Huang J, Wang B, et al. Exosomal transfer of miR-501 confers doxorubicin resistance and tumorigenesis via targeting of BLID in gastric cancer. Cancer Lett. 2019;459:122-134 pubmed publisher |
| Li J, Li Z, Wu Y, Diao P, Zhang W, Wang Y, et al. Overexpression of lncRNA WWTR1-AS1 associates with tumor aggressiveness and unfavorable survival in head-neck squamous cell carcinoma. J Cell Biochem. 2019;120:18266-18277 pubmed publisher |
| Zhou W, Ma L, Yang J, Qiao H, Li L, Guo Q, et al. Potent and specific MTH1 inhibitors targeting gastric cancer. Cell Death Dis. 2019;10:434 pubmed publisher |
| Chen P, Hu M, Liu F, Yu H, Chen C. S-allyl-l-cysteine (SAC) protects hepatocytes from alcohol-induced apoptosis. FEBS Open Bio. 2019;9:1327-1336 pubmed publisher |
| Wang H, Tong X, Zhang Z, Sun Y, Yan W, Xu Z, et al. MYCT1 represses apoptosis of laryngeal cancerous cells through the MAX/miR-181a/NPM1 pathway. FEBS J. 2019;: pubmed publisher |
| Zhou L, Wang S, Cao L, Ren X, Li Y, Shao J, et al. Lead acetate induces apoptosis in Leydig cells by activating PPARγ/caspase-3/PARP pathway. Int J Environ Health Res. 2019;:1-11 pubmed publisher |
| Zhao R, Jiang S, Ru N, Jiao B, Yu Z. Comparison of hypoxic effects induced by chemical and physical hypoxia on cardiomyocytes. Can J Physiol Pharmacol. 2019;: pubmed publisher |
| Xu W, Hu G, Da Costa C, Tang J, Li Q, Du L, et al. Long noncoding RNA UBE2R2-AS1 promotes glioma cell apoptosis via targeting the miR-877-3p/TLR4 axis. Onco Targets Ther. 2019;12:3467-3480 pubmed publisher |
| Lin J, Jia C, Wang Y, Jiang S, Jia Z, Chen N, et al. Therapeutic potential of pravastatin for random skin flaps necrosis: involvement of promoting angiogenesis and inhibiting apoptosis and oxidative stress. Drug Des Devel Ther. 2019;13:1461-1472 pubmed publisher |
| Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, et al. Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats. Life Sci. 2019;: pubmed publisher |
| Zhou X, Chu X, Yuan H, Qiu J, Zhao C, Xin D, et al. Mesenchymal stem cell derived EVs mediate neuroprotection after spinal cord injury in rats via the microRNA-21-5p/FasL gene axis. Biomed Pharmacother. 2019;115:108818 pubmed publisher |
| Liu Y, Wang H, Liu N, Du J, Lan X, Qi X, et al. Oxymatrine protects neonatal rat against hypoxic-ischemic brain damage via PI3K/Akt/GSK3β pathway. Life Sci. 2019;: pubmed publisher |
| Deng C, Li J, Li L, Sun F, Xie J. Effects of hypoxia ischemia on caspase-3 expression and neuronal apoptosis in the brain of neonatal mice. Exp Ther Med. 2019;17:4517-4521 pubmed publisher |
| Li X, Liu Y, Zhou J, Li W, Guo H, Ma H. Enhanced expression of circular RNA hsa_circ_000984 promotes cells proliferation and metastasis in non-small cell lung cancer by modulating Wnt/β-catenin pathway. Eur Rev Med Pharmacol Sci. 2019;23:3366-3374 pubmed publisher |
| Zhang J, Yao D, Zhang J, Song Y, Mo F, Chu X, et al. TGF-β mediates thoracic radiation-induced abscopal effects of testis injury in rat. Biochem Biophys Res Commun. 2019;: pubmed publisher |
| Bi W, Xiao J, Liu R, Zhou L, Zhang S, Yang M, et al. Identification of a 3,3-difluorinated tetrahydropyridinol compound as a novel antitumor agent for hepatocellular carcinoma acting via cell cycle arrest through disturbing CDK7-mediated phosphorylation of Cdc2. Invest New Drugs. 2019;: pubmed publisher |
| Deng X, Ji Z, Xu B, Guo L, Xu L, Qin T, et al. Suppressing the Na+/H+ exchanger 1: a new sight to treat depression. Cell Death Dis. 2019;10:370 pubmed publisher |
| Yang G, Ma H, Wu Y, Zhou B, Zhang C, Chai C, et al. Activation of TRPC6 channels contributes to (+)-conocarpan-induced apoptotic cell death in HK-2 cells. Food Chem Toxicol. 2019;129:281-290 pubmed publisher |
| Tang F, Liu M, Zeng O, Tan W, Long J, Liu S, et al. Gefitinib-coated balloon inhibits the excessive hyperplasia of intima after vascular injuries through PI3K/AKT pathway. Technol Health Care. 2019;27:331-343 pubmed publisher |
| Dong Q, Yang B, Han J, Zhang M, Liu W, Zhang X, et al. A novel hydrogen sulfide-releasing donor, HA-ADT, suppresses the growth of human breast cancer cells through inhibiting the PI3K/AKT/mTOR and Ras/Raf/MEK/ERK signaling pathways. Cancer Lett. 2019;: pubmed publisher |
| Tian L, Su C, Wang Q, Wu F, Bai R, Zhang H, et al. Chlorogenic acid: A potent molecule that protects cardiomyocytes from TNF-α-induced injury via inhibiting NF-κB and JNK signals. J Cell Mol Med. 2019;23:4666-4678 pubmed publisher |
| Yang H, Qiu B, Chen S, Xun Y, Pan Y, Chen M, et al. Soluble CXCL16 promotes TNF-α-induced apoptosis in DLBCL via the AMAD10-NF-κB regulatory feedback loop. Cell Biol Int. 2019;: pubmed publisher |
| Liang L, Tu Y, Lu J, Wang P, Guo Z, Wang Q, et al. Dkk1 exacerbates doxorubicin-induced cardiotoxicity by inhibiting the Wnt/β-catenin signaling pathway. J Cell Sci. 2019;132: pubmed publisher |
| Wang R, Li D, Ouyang J, Tian X, Zhao Y, Peng X, et al. Leonurine alleviates LPS-induced myocarditis through suppressing the NF-кB signaling pathway. Toxicology. 2019;422:1-13 pubmed publisher |
| Jin C, Fu W, Zhang D, Xing W, Xia W, Wei Z, et al. The protective role of IL-1Ra on intestinal ischemia reperfusion injury by anti-oxidative stress via Nrf2/HO-1 pathway in rat. Biomed J. 2019;42:36-45 pubmed publisher |
| Yang Y, Pang B, Liu Z, Li J, Zhang Z, Zhang R, et al. 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation. Oxid Med Cell Longev. 2019;2019:1292891 pubmed publisher |
| Guo L, Lin J, Xue Y, An G, Zhang J, Zhang K, et al. Effects of 220 MHz Pulsed Modulated Radiofrequency Field on the Sperm Quality in Rats. Int J Environ Res Public Health. 2019;16: pubmed publisher |
| Dong S, Ji J, Hu L, Wang H. Dihydromyricetin alleviates acetaminophen-induced liver injury via the regulation of transformation, lipid homeostasis, cell death and regeneration. Life Sci. 2019;227:20-29 pubmed publisher |
| Liu S, Shen M, Li C, Wei Y, Meng X, Li R, et al. PKCδ contributes to oxidative stress-induced apoptosis in porcine ovarian granulosa cells via activating JNK. Theriogenology. 2019;131:89-95 pubmed publisher |
| Zhu Y, Meng Y, Zhao Y, Zhu J, Xu H, Zhang E, et al. Toxicological exploration of peptide-based cationic liposomes in siRNA delivery. Colloids Surf B Biointerfaces. 2019;179:66-76 pubmed publisher |
| Yin F, Yan J, Zhao Y, Guo K, Zhang Z, Li A, et al. Bone marrow mesenchymal stem cells repair Cr (VI)- injured kidney by regulating mitochondria-mediated apoptosis and mitophagy mediated via the MAPK signaling pathway. Ecotoxicol Environ Saf. 2019;176:234-241 pubmed publisher |
| Li T, Li L, Wu X, Tian K, Wang Y. The oncogenic role of GNL3 in the progression and metastasis of osteosarcoma. Cancer Manag Res. 2019;11:2179-2188 pubmed publisher |
| Ren H, Yang H, Xie M, Wen Y, Liu Q, Li X, et al. Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide. Arch Oral Biol. 2019;101:108-121 pubmed publisher |
| Lu G, Li X, Mohamed O K, Wang D, Meng F. Design, synthesis and biological evaluation of novel uracil derivatives bearing 1, 2, 3-triazole moiety as thymidylate synthase (TS) inhibitors and as potential antitumor drugs. Eur J Med Chem. 2019;171:282-296 pubmed publisher |
| Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al. Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed |
| Huang Z, Zheng Y, Li N, Cai S, Huang Y, Wang J, et al. Protective effects of specific cannabinoid receptor 2 agonist GW405833 on concanavalin A-induced acute liver injury in mice. Acta Pharmacol Sin. 2019;: pubmed publisher |
| Du W, Wang N, Li F, Jia K, An J, Liu Y, et al. STAT3 phosphorylation mediates high glucose-impaired cell autophagy in an HDAC1-dependent and -independent manner in Schwann cells of diabetic peripheral neuropathy. FASEB J. 2019;:fj201900127R pubmed publisher |
| Zhang Y, Gao J, Sun W, Wen X, Xi Y, Wang Y, et al. H2S restores the cardioprotective effects of ischemic post-conditioning by upregulating HB-EGF/EGFR signaling. Aging (Albany NY). 2019;11:1745-1758 pubmed publisher |
| Wei W, Lan X, Liu N, Yang J, Du J, Ma L, et al. Echinacoside Alleviates Hypoxic-Ischemic Brain Injury in Neonatal Rat by Enhancing Antioxidant Capacity and Inhibiting Apoptosis. Neurochem Res. 2019;44:1582-1592 pubmed publisher |
| Cao X, He Y, Li X, Xu Y, Liu X. The IRE1α-XBP1 pathway function in hypoxia-induced pulmonary vascular remodeling, is upregulated by quercetin, inhibits apoptosis and partially reverses the effect of quercetin in PASMCs. Am J Transl Res. 2019;11:641-654 pubmed |
| Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, et al. α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation. Int J Oncol. 2019;54:1601-1612 pubmed publisher |
| Zhu L, Li D, Chen C, Wang G, Shi J, Zhang F. Activation of Nrf2 signaling by Icariin protects against 6-OHDA-induced neurotoxicity. Biotechnol Appl Biochem. 2019;: pubmed publisher |
| Zou W, Niu C, Fu Z, Gong C. PNS-R1 inhibits Dex-induced bronchial epithelial cells apoptosis in asthma through mitochondrial apoptotic pathway. Cell Biosci. 2019;9:18 pubmed publisher |
| Li W, Cao J, Liu J, Chu W, Zhang C, Chen S, et al. Downregulation of CDKL1 suppresses neuroblastoma cell proliferation, migration and invasion. Cell Mol Biol Lett. 2019;24:19 pubmed publisher |
| Wang D, Hong Y, Chen Y, Dong P, Liu S, Gao Y, et al. PEST-containing nuclear protein regulates cell proliferation, migration, and invasion in lung adenocarcinoma. Oncogenesis. 2019;8:22 pubmed publisher |
| Deng S, Nie Z, Peng P, Liu Y, Xing S, Long L, et al. Decrease of GSK3β Ser-9 Phosphorylation Induced Osteoblast Apoptosis in Rat Osteoarthritis Model. Curr Med Sci. 2019;39:75-80 pubmed publisher |
| Wu D, Liu Z, Li J, Zhang Q, Zhong P, Teng T, et al. Epigallocatechin-3-gallate inhibits the growth and increases the apoptosis of human thyroid carcinoma cells through suppression of EGFR/RAS/RAF/MEK/ERK signaling pathway. Cancer Cell Int. 2019;19:43 pubmed publisher |
| Yu Q, Wu L, Liu T, Li S, Feng J, Mao Y, et al. Protective effects of levo-tetrahydropalmatine on hepatic ischemia/reperfusion injury are mediated by inhibition of the ERK/NF-κB pathway. Int Immunopharmacol. 2019;70:435-445 pubmed publisher |
| Zhang Q, Meng X, Qin G, Xue X, Dang N. Lyn Kinase Promotes the Proliferation of Malignant Melanoma Cells through Inhibition of Apoptosis and Autophagy via the PI3K/Akt Signaling Pathway. J Cancer. 2019;10:1197-1208 pubmed publisher |
| Shah S, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, et al. Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway. Int J Mol Sci. 2019;20: pubmed publisher |
| Terashi T, Otsuka S, Takada S, Nakanishi K, Ueda K, Sumizono M, et al. Neuroprotective effects of different frequency preconditioning exercise on neuronal apoptosis after focal brain ischemia in rats. Neurol Res. 2019;41:510-518 pubmed publisher |
| Zheng Y, Xiao R, Zhang L, Yan H, Wang J, Lv L. A Novel Mutant of rLj-RGD3 (rLj-112) Suppressed the Proliferation and Metastasis of B16 Cells through the EGFR Signaling Pathway. Mar Drugs. 2019;17: pubmed publisher |
| Li H, Dai Y, Luo Z, Nie D. Cloning of a new testis-enriched gene C4orf22 and its role in cell cycle and apoptosis in mouse spermatogenic cells. Mol Biol Rep. 2019;: pubmed publisher |
| Li L, Liu M, Zhang Z, Zhang W, Liu N, Sheng X, et al. Derlin1 functions as an oncogene in cervical cancer via AKT/mTOR signaling pathway. Biol Res. 2019;52:8 pubmed publisher |
| Ding Y, Li N, Sun J, Zhang L, Guo J, Hao X, et al. Oxymatrine Inhibits Bocavirus MVC Replication, Reduces Viral Gene Expression and Decreases Apoptosis Induced by Viral Infection. Virol Sin. 2019;34:78-87 pubmed publisher |
| Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, et al. Protective effects of resveratrol on random-pattern skin flap survival: an experimental study. Am J Transl Res. 2019;11:379-392 pubmed |
| Lu L, Chen G, Yang J, Ma Z, Yang Y, Hu Y, et al. Bone marrow mesenchymal stem cells suppress growth and promote the apoptosis of glioma U251 cells through downregulation of the PI3K/AKT signaling pathway. Biomed Pharmacother. 2019;112:108625 pubmed publisher |
| Tian W, Guo H, Li C, Cao W, Wang X, Mo D, et al. PFKFB3 promotes endotoxemia-induced myocardial dysfunction through inflammatory signaling and apoptotic induction. Toxicol Appl Pharmacol. 2019;368:26-36 pubmed publisher |
| Cui Y, Feng N, Gu X, Fu F, Li J, Guo H, et al. κ-Opioid receptor stimulation reduces palmitate-induced apoptosis via Akt/eNOS signaling pathway. Lipids Health Dis. 2019;18:52 pubmed publisher |
| Chen L, Wu X, Shen T, Wang X, Wang S, Wang J, et al. Protective effects of ethyl gallate on H2O2-induced mitochondrial dysfunction in PC12 cells. Metab Brain Dis. 2019;34:545-555 pubmed publisher |
| Sun H, Yang B, Zhang H, Song J, Zhang Y, Xing J, et al. RRM2 is a potential prognostic biomarker with functional significance in glioma. Int J Biol Sci. 2019;15:533-543 pubmed publisher |
| Jin M, Ji X, Zhang B, Sheng W, Wang R, Liu K. Synergistic effects of Pb and repeated heat pulse on developmental neurotoxicity in zebrafish. Ecotoxicol Environ Saf. 2019;172:460-470 pubmed publisher |
| Pan H, Wang H, Yu J, Huang X, Hao Y, Zhang C, et al. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials. 2019;199:22-31 pubmed publisher |
| Li D, Cai Z, Wu J, Zhang Y. Bax inhibitor-1 overexpression in prelimbic cortex protects rats against depression-like behavior induced by olfactory bulbectomy and reduces apoptotic and inflammatory signals. Neurol Res. 2019;41:369-377 pubmed publisher |
| Zhang D, Liu X, Wang Q, Li N, Wu S, Wang C. Downregulation of microRNA-196a attenuates ischemic brain injury in rats by directly targeting HMGA1. Eur Rev Med Pharmacol Sci. 2019;23:740-748 pubmed publisher |
| Min X, Huang F, Huang H, Zhao S, Wang G, Zhou M, et al. The Radiosensitization of Sodium Glycididazole on Nasopharyngeal Carcinoma Cells via Enhancing DNA Damage and Promoting Apoptosis. J Cancer. 2019;10:305-312 pubmed publisher |
| Lin Q, Wang W, Lin Y, Lin Z, Yu L, Kang Y, et al. Annexin A7 induction of neuronal apoptosis via effect on glutamate release in a rat model of subarachnoid hemorrhage. J Neurosurg. 2019;:1-11 pubmed publisher |
| Gunaydin C, Avci B, Bozkurt A, Onger M, Balcı H, Bilge S. Effects of agomelatine in rotenone-induced Parkinson's disease in rats. Neurosci Lett. 2019;699:71-76 pubmed publisher |
| Xu B, Lian S, Guo J, Wang J, Zhang L, Li S, et al. Activation of the MAPK signaling pathway induces upregulation of pro-apoptotic proteins in the hippocampi of cold stressed adolescent mice. Neurosci Lett. 2019;699:97-102 pubmed publisher |
| Chen F, Song F, Chen Y, Wang Z, Li Y, Liu M, et al. Exogenous testosterone alleviates cardiac fibrosis and apoptosis via Gas6/Axl pathway in the senescent mice. Exp Gerontol. 2019;119:128-137 pubmed publisher |
| Mao Z, Han X, Chen D, Xu Y, Xu L, Yin L, et al. Potent effects of dioscin against hepatocellular carcinoma through regulating TP53-induced glycolysis and apoptosis regulator (TIGAR)-mediated apoptosis, autophagy, and DNA damage. Br J Pharmacol. 2019;176:919-937 pubmed publisher |
| Zhou M, Feng Z, Ou Y, Peng J, Li K, Gong H, et al. Endoplasmic reticulum stress induces apoptosis of arginine vasopressin neurons in central diabetes insipidus via PI3K/Akt pathway. CNS Neurosci Ther. 2019;25:562-574 pubmed publisher |
| Chen Z, Wang C, Li T, Li K, Yue Y, Liu X, et al. Doxorubicin conjugated with nanodiamonds and in free form commit glioblastoma cells to heterodromous fates. Nanomedicine (Lond). 2019;14:335-351 pubmed publisher |
| Zhao B, Hu T. JTC-801 inhibits the proliferation and metastasis of the Hep G2 hepatoblastoma cell line by regulating the phosphatidylinositol 3-kinase/protein kinase B signalling pathway. Oncol Lett. 2019;17:1939-1945 pubmed publisher |
| Li E, Sun Y, Lv G, Li Y, Zhang Z, Hu Z, et al. Sinoporphyrin sodium based sonodynamic therapy induces anti-tumor effects in hepatocellular carcinoma and activates p53/caspase 3 axis. Int J Biochem Cell Biol. 2019;: pubmed publisher |
| Li T, Xu Y, Li K, Wang C, Liu X, Yue Y, et al. Doxorubicin-polyglycerol-nanodiamond composites stimulate glioblastoma cell immunogenicity through activation of autophagy. Acta Biomater. 2019;86:381-394 pubmed publisher |
| Li Z, Yu Y, Wang M, Xu H, Han B, Jiang P, et al. Anti-breast Cancer Activity of SPG-56 from Sweet Potato in MCF-7 Bearing Mice in Situ through Promoting Apoptosis and Inhibiting Metastasis. Sci Rep. 2019;9:146 pubmed publisher |
| Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, et al. Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells. Toxins (Basel). 2019;11: pubmed publisher |
| He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, et al. Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice. Int Immunopharmacol. 2019;68:171-178 pubmed publisher |
| Zhang Y, Li Q, Yu S, Zhu C, Zhang Z, Cao H, et al. Long non-coding RNA FAM84B-AS promotes resistance of gastric cancer to platinum drugs through inhibition of FAM84B expression. Biochem Biophys Res Commun. 2019;: pubmed publisher |
| Wu D, Liu S, Gao Y, Lu D, Hong Y, Chen Y, et al. Tumour necrosis factor-α-induced protein 8-like 2 is a novel regulator of proliferation, migration, and invasion in human rectal adenocarcinoma cells. J Cell Mol Med. 2019;23:1698-1713 pubmed publisher |
| Zhu Y, Dong M, Yang J, Zhang J. Evaluation of Iodine-125 Interstitial Brachytherapy Using Micro-Positron Emission Tomography/Computed Tomography with 18F-Fluorodeoxyglucose in Hepatocellular Carcinoma HepG2 Xenografts. Med Sci Monit. 2019;25:371-380 pubmed publisher |
| Li X, Du J, Lu Y, Lin X. Neuroprotective effects of rapamycin on spinal cord injury in rats by increasing autophagy and Akt signaling. Neural Regen Res. 2019;14:721-727 pubmed publisher |
| Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed publisher |
| Chen Y, Wang D, Peng H, Chen X, Han X, Yu J, et al. Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression. Mol Cancer. 2019;18:1 pubmed publisher |
| Liu P, Zhang H, Hu K, Zhou X, Tang S. Sensory plasticity of carotid body is correlated with oxidative stress in paraventricular nucleus during chronic intermittent hypoxia. J Cell Physiol. 2019;234:13534-13543 pubmed publisher |
| Zhang D, Zhang J, Zeng J, Li Z, Zuo H, Huang C, et al. Nano-Gold Loaded with Resveratrol Enhance the Anti-Hepatoma Effect of Resveratrol In Vitro and In Vivo. J Biomed Nanotechnol. 2019;15:288-300 pubmed publisher |
| Li Z, Rong L, Lian H, Cheng J, Wu X, Li X. Knockdown MTMR14 promotes cell apoptosis and inhibits migration in liver cancer cells. Gene. 2019;691:106-113 pubmed publisher |
| Li Y, Zheng Q, Sun D, Cui X, CHEN S, Bulbul A, et al. Dehydroepiandrosterone stimulates inflammation and impairs ovarian functions of polycystic ovary syndrome. J Cell Physiol. 2019;234:7435-7447 pubmed publisher |
| Yang C, Li X, Li S, Chai X, Guan L, Qiao L, et al. Organotypic slice culture based on in ovo electroporation for chicken embryonic central nervous system. J Cell Mol Med. 2019;23:1813-1826 pubmed publisher |
| Li Y, Zhang J, Su L, Kellum J, Peng Z. Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:558-569 pubmed publisher |
| Jin M, Xiao Z, Zhang S, Men X, Li X, Zhang B, et al. Possible involvement of Fas/FasL-dependent apoptotic pathway in α-bisabolol induced cardiotoxicity in zebrafish embryos. Chemosphere. 2019;219:557-566 pubmed publisher |
| Zhang X, Liu J, Gu Y, Sun C, Qu F. Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs. Cell Biol Int. 2019;43:158-166 pubmed publisher |
| Yang Q, Lin J, Zhang H, Liu Y, Kan M, Xiu Z, et al. Ginsenoside Compound K Regulates Amyloid β via the Nrf2/Keap1 Signaling Pathway in Mice with Scopolamine Hydrobromide-Induced Memory Impairments. J Mol Neurosci. 2019;67:62-71 pubmed publisher |
| Cao P, Feng Y, Deng M, Li J, Cai H, Meng Q, et al. MiR-15b is a key regulator of proliferation and apoptosis of chondrocytes from patients with condylar hyperplasia by targeting IGF1, IGF1R and BCL2. Osteoarthritis Cartilage. 2019;27:336-346 pubmed publisher |
| Zheng L, Hu Y, Zhao X, Yin L, Xu L, Qi Y, et al. Dioscin ameliorates intestinal ischemia/reperfusion injury via adjusting miR-351-5p/MAPK13-mediated inflammation and apoptosis. Pharmacol Res. 2019;139:431-439 pubmed publisher |
| Otsuka S, Sakakima H, Terashi T, Takada S, Nakanishi K, Kikuchi K. Preconditioning exercise reduces brain damage and neuronal apoptosis through enhanced endogenous 14-3-3γ after focal brain ischemia in rats. Brain Struct Funct. 2019;224:727-738 pubmed publisher |
| Jia Z, Peng J, Yang Z, Chen J, Liu L, Luo D, et al. Long non-coding RNA TP73‑AS1 promotes colorectal cancer proliferation by acting as a ceRNA for miR‑103 to regulate PTEN expression. Gene. 2019;685:222-229 pubmed publisher |
| Duan J, Deng T, Kang J, Chen M. DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats. Environ Pollut. 2019;245:316-324 pubmed publisher |
| Liu H, Wu Q, Cao J, Wang X, Song Y, Mei W, et al. A phenanthroline derivative enhances radiosensitivity of hepatocellular carcinoma cells by inducing mitochondria-dependent apoptosis. Eur J Pharmacol. 2019;843:285-291 pubmed publisher |
| Qu C, Ma J, Zhang Y, Han C, Huang L, Shen L, et al. Estrogen receptor variant ER-α36 promotes tamoxifen agonist activity in glioblastoma cells. Cancer Sci. 2019;110:221-234 pubmed publisher |
| Gong Z, Kuang Z, Li H, Li C, Ali M, Huang F, et al. Regulation of host cell pyroptosis and cytokines production by Mycobacterium tuberculosis effector PPE60 requires LUBAC mediated NF-κB signaling. Cell Immunol. 2019;335:41-50 pubmed publisher |
| Wang J, Shao L, Wang C, Zhou H, Yuan C, Huang W. Synergetic Inhibition of Human Colorectal Cancer Cells by Combining Polyyne-Enriched Fraction from Oplopanax elatus and Irinotecan. Nutr Cancer. 2019;71:472-482 pubmed publisher |
| Wang N, Li R, Xue M. Potential regulatory network in the PSG10P/miR-19a-3p/IL1RAP pathway is possibly involved in preeclampsia pathogenesis. J Cell Mol Med. 2019;23:852-864 pubmed publisher |
| Geng X, Liu L, Tsai K, Liu Z. Role of ZIP8 in regulation of cisplatin sensitivity through Bcl-2. Toxicol Appl Pharmacol. 2019;362:52-58 pubmed publisher |
| Zhang P, Du J, Zhao H, Cheng Y, Dong S, Yang Y, et al. Radioprotective effects of roxadustat (FG-4592) in haematopoietic system. J Cell Mol Med. 2019;23:349-356 pubmed publisher |
| Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed publisher |
| Fan J, Wu M, Wang J, Ren D, Zhao J, Yang G. 1,7-Bis(4-hydroxyphenyl)-1,4-heptadien-3-one induces lung cancer cell apoptosis via the PI3K/Akt and ERK1/2 pathways. J Cell Physiol. 2019;234:6336-6349 pubmed publisher |
| Jing Z, Wang C, Yang Q, Wei X, Jin Y, Meng Q, et al. Luteolin attenuates glucocorticoid-induced osteoporosis by regulating ERK/Lrp-5/GSK-3β signaling pathway in vivo and in vitro. J Cell Physiol. 2019;234:4472-4490 pubmed publisher |
| Pan J, Zhou H, Zhu S, Huang J, Zhao X, Ding H, et al. Nicotinamide phosphoribosyl transferase regulates cell growth via the Sirt1/P53 signaling pathway and is a prognosis marker in colorectal cancer. J Cell Physiol. 2019;234:4385-4395 pubmed publisher |
| Yin B, Hou X, Lu M. Astragaloside IV attenuates myocardial ischemia/reperfusion injury in rats via inhibition of calcium-sensing receptor-mediated apoptotic signaling pathways. Acta Pharmacol Sin. 2019;40:599-607 pubmed publisher |
| Xu L, Xing Q, Huang T, Zhou J, Liu T, Cui Y, et al. HDAC1 Silence Promotes Neuroprotective Effects of Human Umbilical Cord-Derived Mesenchymal Stem Cells in a Mouse Model of Traumatic Brain Injury via PI3K/AKT Pathway. Front Cell Neurosci. 2018;12:498 pubmed publisher |
| Jiang X, Du Y, Meng X, Zhang H, Zhao D, Zhao L, et al. Low-Dose Radiation Enhanced Inhibition of Breast Tumor Xenograft and Reduced Myocardial Injury Induced by Doxorubicin. Dose Response. 2018;16:1559325818813061 pubmed publisher |
| Yu Q, Liu T, Li S, Feng J, Wu L, Wang W, et al. The Protective Effects of Levo-Tetrahydropalmatine on ConA-Induced Liver Injury Are via TRAF6/JNK Signaling. Mediators Inflamm. 2018;2018:4032484 pubmed publisher |
| Deng S, Zhou J, Fang H, Nie Z, Chen S, Peng H. Sesamin Protects the Femoral Head From Osteonecrosis by Inhibiting ROS-Induced Osteoblast Apoptosis in Rat Model. Front Physiol. 2018;9:1787 pubmed publisher |
| Mao J, Yi M, Wang R, Huang Y, Chen M. Protective Effects of Costunolide Against D-Galactosamine and Lipopolysaccharide-Induced Acute Liver Injury in Mice. Front Pharmacol. 2018;9:1469 pubmed publisher |
| Chen Y, Tzeng D, Huang Y, Lin C, Lo U, Wu C, et al. Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways. Cancers (Basel). 2018;11: pubmed publisher |
| Ye Y, Wu Y, Wang J. Pyrroline-5-carboxylate reductase 1 promotes cell proliferation via inhibiting apoptosis in human malignant melanoma. Cancer Manag Res. 2018;10:6399-6407 pubmed publisher |
| Li Q, Ma R, Zhang M. XRCC1 rs1799782 (C194T) polymorphism correlated with tumor metastasis and molecular subtypes in breast cancer. Onco Targets Ther. 2018;11:8435-8444 pubmed publisher |
| Deng J, Feng J, Liu T, Lu X, Wang W, Liu N, et al. Beraprost sodium preconditioning prevents inflammation, apoptosis, and autophagy during hepatic ischemia-reperfusion injury in mice via the P38 and JNK pathways. Drug Des Devel Ther. 2018;12:4067-4082 pubmed publisher |
| Xu X, Cao L, Zhang Y, Lian H, Sun Z, Cui Y. Effects of mdig on proliferation and apoptosis of lung cancer cells. Oncol Lett. 2018;16:7146-7151 pubmed publisher |
| Chang M, Wu M, Li H. Antitumor activities of novel glycyrrhetinic acid-modified curcumin-loaded cationic liposomes in vitro and in H22 tumor-bearing mice. Drug Deliv. 2018;25:1984-1995 pubmed publisher |
| Gu R, Tang W, Lei B, Jiang C, Song F, Xu G. Synthesized glucocorticoid-induced leucine zipper peptide inhibits photoreceptor apoptosis and protects retinal function in light-induced retinal degeneration model. Clin Exp Ophthalmol. 2018;: pubmed publisher |
| Liu B, Xu L, Dai E, Tian J, Li J. Anti-tumoral potential of MDA19 in human osteosarcoma via suppressing PI3K/Akt/mTOR signaling pathway. Biosci Rep. 2018;38: pubmed publisher |
| Ding W, Ji T, Xiong W, Li T, Pu D, Liu R. Realgar, a traditional Chinese medicine, induces apoptosis of HPV16-positive cervical cells through a HPV16 E7-related pathway. Drug Des Devel Ther. 2018;12:3459-3469 pubmed publisher |
| Qiao J, Wang W, Zhang Y. Aclidinium inhibits proliferation and metastasis of ovarian cancer SKOV3 cells via downregulating PI3K/AKT/mTOR signaling pathway. Oncol Lett. 2018;16:6417-6422 pubmed publisher |
| Lin J, Lin R, Li S, Wu H, Ding J, Xiang G, et al. Salvianolic Acid B Promotes the Survival of Random-Pattern Skin Flaps in Rats by Inducing Autophagy. Front Pharmacol. 2018;9:1178 pubmed publisher |
| Fan Y, Guan S, Luo L, Li Y, Yang L, Zhou X, et al. Tetrahydroxystilbene glucoside relieves the chronic inflammatory pain by inhibiting neuronal apoptosis, microglia activation, and GluN2B overexpression in anterior cingulate cortex. Mol Pain. 2018;14:1744806918814367 pubmed publisher |
| Wang J, Yang C, Yuan Z, Yi J, Wu J. T-2 Toxin Exposure Induces Apoptosis in TM3 Cells by Inhibiting Mammalian Target of Rapamycin/Serine/Threonine Protein Kinase(mTORC2/AKT) to Promote Ca2+Production. Int J Mol Sci. 2018;19: pubmed publisher |
| Tian T, Sun J, Wang J, Liu Y, Liu H. Isoliquiritigenin inhibits cell proliferation and migration through the PI3K/AKT signaling pathway in A549 lung cancer cells. Oncol Lett. 2018;16:6133-6139 pubmed publisher |
| Yue X, Li M, Chen D, Xu Z, Sun S. UNBS5162 induces growth inhibition and apoptosis via inhibiting PI3K/AKT/mTOR pathway in triple negative breast cancer MDA-MB-231 cells. Exp Ther Med. 2018;16:3921-3928 pubmed publisher |
| Wang J, Li H, Wang X, Shen T, Wang S, Ren D. Alisol B-23-acetate, a tetracyclic triterpenoid isolated from Alisma orientale, induces apoptosis in human lung cancer cells via the mitochondrial pathway. Biochem Biophys Res Commun. 2018;505:1015-1021 pubmed publisher |
| Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, et al. Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells. Chem Biol Interact. 2018;296:145-153 pubmed publisher |
| Wang Z, Ren J, Liu Q, Li J, Wu X, Wang W, et al. Hypermucoviscous Klebsiella pneumoniae infections induce platelet aggregation and apoptosis and inhibit maturation of megakaryocytes. Thromb Res. 2018;171:45-54 pubmed publisher |
| Lin H, Wang T, Ruan Y, Liu K, Li H, Wang S, et al. Rapamycin Supplementation May Ameliorate Erectile Function in Rats With Streptozotocin-Induced Type 1 Diabetes by Inducing Autophagy and Inhibiting Apoptosis, Endothelial Dysfunction, and Corporal Fibrosis. J Sex Med. 2018;15:1246-1259 pubmed publisher |
| Mu Z, Sun Q. Cantharidin inhibits melanoma cell proliferation via the miR‑21‑mediated PTEN pathway. Mol Med Rep. 2018;18:4603-4610 pubmed publisher |
| Zhao W, Che C, Liu K, Zhang J, Jiang N, Yuan K, et al. Fenretinide Inhibits Neutrophil Recruitment and IL-1β Production in Aspergillus fumigatus Keratitis. Cornea. 2018;37:1579-1585 pubmed publisher |
| Liu S, Li X, Gao J, Liu Y, Shi J, Gong Q. Icariside II, a Phosphodiesterase-5 Inhibitor, Attenuates Beta-Amyloid-Induced Cognitive Deficits via BDNF/TrkB/CREB Signaling. Cell Physiol Biochem. 2018;49:985 pubmed publisher |
| Tian Z, Jiang H, Lu Z. MiR-320 regulates cardiomyocyte apoptosis induced by ischemia-reperfusion injury by targeting AKIP1. Cell Mol Biol Lett. 2018;23:41 pubmed publisher |
| Yang Y, Yu S, Liu N, Xu H, Gong Y, Wu Y, et al. Transcription Factor FOXO3a Is a Negative Regulator of Cytotoxicity of Fusarium mycotoxin in GES-1 Cells. Toxicol Sci. 2018;166:370-381 pubmed publisher |
| Xu H, Li Y, Han B, Li Z, Wang B, Jiang P, et al. Anti-breast-Cancer Activity Exerted by β-Sitosterol-d-glucoside from Sweet Potato via Upregulation of MicroRNA-10a and via the PI3K-Akt Signaling Pathway. J Agric Food Chem. 2018;66:9704-9718 pubmed publisher |
| Chen Y, Li Y, Wang X, Meng Y, Zhang Q, Zhu J, et al. Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway. Phytother Res. 2018;32:2447-2455 pubmed publisher |
| Chen Z, Wang X, Ashraf U, Zheng B, Ye J, Zhou D, et al. Activation of neuronal N-methyl-D-aspartate receptor plays a pivotal role in Japanese encephalitis virus-induced neuronal cell damage. J Neuroinflammation. 2018;15:238 pubmed publisher |
| You C, Zhang S, Sun Y, Zhang S, Tang G, Tang F, et al. β-catenin decreases acquired TRAIL resistance in non-small-cell lung cancer cells by regulating the redistribution of death receptors. Int J Oncol. 2018;53:2258-2268 pubmed publisher |
| Wu W, Nie L, Zhang L, Li Y. The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells. Cell Mol Biol Lett. 2018;23:37 pubmed publisher |
| He Q, Zhou X, Liu Y, Gou W, Cui J, Li Z, et al. Titanium dioxide nanoparticles induce mouse hippocampal neuron apoptosis via oxidative stress- and calcium imbalance-mediated endoplasmic reticulum stress. Environ Toxicol Pharmacol. 2018;63:6-15 pubmed publisher |
| Song X, Liu Y, Shao J, Zhang Z, Xie C, Qiao X, et al. Rapid induction of apoptosis in tumor cells treated with a new platinum(II) complex based on amino-thiazolidinone. Eur J Med Chem. 2018;157:188-197 pubmed publisher |
| Duan Y, Jin Y, Guo M, Duan L, Wang J. Differentially expressed genes of HepG2 cells treated with gecko polypeptide mixture. J Cancer. 2018;9:2723-2733 pubmed publisher |
| Chen B, Wei W, Huang X, Xie X, Kong Y, Dai D, et al. circEPSTI1 as a Prognostic Marker and Mediator of Triple-Negative Breast Cancer Progression. Theranostics. 2018;8:4003-4015 pubmed publisher |
| Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, et al. Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol. 2018;234:777-788 pubmed publisher |
| Li T, Li K, Zhang Q, Wang C, Yue Y, Chen Z, et al. Dendritic cell-mediated delivery of doxorubicin-polyglycerol-nanodiamond composites elicits enhanced anti-cancer immune response in glioblastoma. Biomaterials. 2018;181:35-52 pubmed publisher |
| Li Z, Chen B, Dong W, Xu W, Song M, Fang M, et al. Epigenetic activation of PERP transcription by MKL1 contributes to ROS-induced apoptosis in skeletal muscle cells. Biochim Biophys Acta Gene Regul Mech. 2018;: pubmed publisher |
| Yi C, Wan X, Zhang Y, Fu F, Zhao C, Qin R, et al. SNORA42 enhances prostate cancer cell viability, migration and EMT and is correlated with prostate cancer poor prognosis. Int J Biochem Cell Biol. 2018;102:138-150 pubmed publisher |
| Wang X, Liu W, Wang P, Li S. RNA interference of long noncoding RNA HOTAIR suppresses autophagy and promotes apoptosis and sensitivity to cisplatin in oral squamous cell carcinoma. J Oral Pathol Med. 2018;47:930-937 pubmed publisher |
| Zhang Y, Wang C, Jin Y, Yang Q, Meng Q, Liu Q, et al. Activating the PGC-1α/TERT Pathway by Catalpol Ameliorates Atherosclerosis via Modulating ROS Production, DNA Damage, and Telomere Function: Implications on Mitochondria and Telomere Link. Oxid Med Cell Longev. 2018;2018:2876350 pubmed publisher |
| Xu B, Lian S, Li S, Guo J, Wang J, Wang D, et al. GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose. Brain Res Bull. 2018;142:163-175 pubmed publisher |
| Wang L, Hu Y, Hao Y, Li L, Zheng C, Zhao H, et al. Tumor-targeting core-shell structured nanoparticles for drug procedural controlled release and cancer sonodynamic combined therapy. J Control Release. 2018;286:74-84 pubmed publisher |
| Zhang G, Lu D, Duan S, Gao Y, Liu S, Hong Y, et al. Hydrogen Sulfide Alleviates Lipopolysaccharide-Induced Diaphragm Dysfunction in Rats by Reducing Apoptosis and Inflammation through ROS/MAPK and TLR4/NF-κB Signaling Pathways. Oxid Med Cell Longev. 2018;2018:9647809 pubmed publisher |
| Shen D, Tian L, Shen T, Sun H, Liu P. Alpha-Lipoic Acid Protects Human Aortic Endothelial Cells Against H2O2-Induced Injury and Inhibits Atherosclerosis in Ovariectomized Low Density Lipoprotein Receptor Knock-Out Mice. Cell Physiol Biochem. 2018;47:2261-2277 pubmed publisher |
| Xu N, Fan W, Zhou X, Liu Y, Ma P, Qi S, et al. Probiotics decrease depressive behaviors induced by constipation via activating the AKT signaling pathway. Metab Brain Dis. 2018;33:1625-1633 pubmed publisher |
| Sun X, Huang S, Zhang X, Wang X. CD300A promotes tumor progression by PECAM1, ADCY7 and AKT pathway in acute myeloid leukemia. Oncotarget. 2018;9:27574-27584 pubmed publisher |
| Qin J, Shi H, Xu Y, Zhao F, Wang Q. Tanshinone IIA inhibits cervix carcinoma stem cells migration and invasion via inhibiting YAP transcriptional activity. Biomed Pharmacother. 2018;105:758-765 pubmed publisher |
| Ni Y, Hsieh C, Wang J, Fang K. Teroxirone motivates apoptotic death in tumorspheres of human lung cancer cells. Chem Biol Interact. 2018;291:137-143 pubmed publisher |
| Zhao J, Zhao Q, Hu H, Liao J, Lin J, Xia C, et al. The ASH1-miR-375-YWHAZ Signaling Axis Regulates Tumor Properties in Hepatocellular Carcinoma. Mol Ther Nucleic Acids. 2018;11:538-553 pubmed publisher |
| Li X, Liang J, Mohamed O K, Zhang T, Lu G, Meng F. Design, synthesis and biological evaluation of N-phenyl-(2,4-dihydroxypyrimidine-5-sulfonamido)benzoyl hydrazide derivatives as thymidylate synthase (TS) inhibitors and as potential antitumor drugs. Eur J Med Chem. 2018;154:267-279 pubmed publisher |
| Feng J, Niu P, Chen K, Wu L, Liu T, Xu S, et al. Salidroside mediates apoptosis and autophagy inhibition in concanavalin A-induced liver injury. Exp Ther Med. 2018;15:4599-4614 pubmed publisher |
| Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, et al. The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPAR? Activation. PPAR Res. 2018;2018:3180396 pubmed publisher |
| Feng W, Liang C, Wang C, Yu X, Li Q, Yang H. Knockdown of ribosomal protein S15A inhibits proliferation of breast cancer cells through induction of apoptosis in vitro. Cytotechnology. 2018;70:1315-1323 pubmed publisher |
| Wang X, Yu H, You J, Wang C, Feng C, Liu Z, et al. Memantine can improve chronic ethanol exposure-induced spatial memory impairment in male C57BL/6 mice by reducing hippocampal apoptosis. Toxicology. 2018;406-407:21-32 pubmed publisher |
| He J, Chen Q, Gu H, Chen J, Zhang E, Guo X, et al. Therapeutic effects of the novel subtype-selective histone deacetylase inhibitor chidamide on myeloma-associated bone disease. Haematologica. 2018;103:1369-1379 pubmed publisher |
| Chen X, Wu Q, Jiang H, Wang J, Zhao Y, Xu Y, et al. SET8 is involved in the regulation of hyperglycemic memory in human umbilical endothelial cells. Acta Biochim Biophys Sin (Shanghai). 2018;50:635-642 pubmed publisher |
| Sun D, Ma H, Ma J, Wang J, Deng X, Hu C, et al. Canonical Transient Receptor Potential Channel 3 Contributes to Febrile Seizure Inducing Neuronal Cell Death and Neuroinflammation. Cell Mol Neurobiol. 2018;38:1215-1226 pubmed publisher |
| Lai X, Su W, Zhao H, Yang S, Zeng T, Wu W, et al. Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells. FEBS Open Bio. 2018;8:743-750 pubmed publisher |
| Cheng Y, Zhao P, Wu S, Yang T, Chen Y, Zhang X, et al. Cisplatin and curcumin co-loaded nano-liposomes for the treatment of hepatocellular carcinoma. Int J Pharm. 2018;545:261-273 pubmed publisher |
| Wu D, Gao Y, Li T, Wang D, Lu D, Liu S, et al. PEST-containing nuclear protein mediates the proliferation, migration, and invasion of human neuroblastoma cells through MAPK and PI3K/AKT/mTOR signaling pathways. BMC Cancer. 2018;18:499 pubmed publisher |
| Zhang H, Zhang W, Jiao F, Li X, Zhang H, Wang L, et al. The Nephroprotective Effect of MS-275 on Lipopolysaccharide (LPS)-Induced Acute Kidney Injury by Inhibiting Reactive Oxygen Species (ROS)-Oxidative Stress and Endoplasmic Reticulum Stress. Med Sci Monit. 2018;24:2620-2630 pubmed publisher |
| Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, et al. Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-? pathway in mice. Biomed Pharmacother. 2018;103:800-811 pubmed publisher |
| Yang Y, Xie F, Qin D, Zong C, Han F, Pu Z, et al. The orphan nuclear receptor NR4A1 attenuates oxidative stress-induced ? cells apoptosis via up-regulation of glutathione peroxidase 1. Life Sci. 2018;203:225-232 pubmed publisher |
| Huang Y, Hu Z. UBIAD1 protects against oxygen-glucose deprivation/reperfusion-induced multiple subcellular organelles injury through PI3K/AKT pathway in N2A cells. J Cell Physiol. 2018;233:7480-7496 pubmed publisher |
| Zhang J, Liu L, Wang J, Ren B, Zhang L, Li W. Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells. J Ethnopharmacol. 2018;221:91-99 pubmed publisher |
| Li L, Sun Z, Xu C, Wu J, Liu G, Cui H, et al. Adenovirus-mediated overexpression of sST2 attenuates cardiac injury in the rat with severe acute pancreatitis. Life Sci. 2018;202:167-174 pubmed publisher |
| Fang Y, Liu G, Xie C, Qian K, Lei X, Liu Q, et al. Pharmacological inhibition of TRPV4 channel suppresses malignant biological behavior of hepatocellular carcinoma via modulation of ERK signaling pathway. Biomed Pharmacother. 2018;101:910-919 pubmed publisher |
| Yin L, Wen X, Lai Q, Li J, Wang X. Lenalidomide improvement of cisplatin antitumor efficacy on triple-negative breast cancer cells in vitro. Oncol Lett. 2018;15:6469-6474 pubmed publisher |
| Zhang Q, Li X, Chen Y, Chen J, Zhu J, Meng Y, et al. Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells. Cancer Chemother Pharmacol. 2018;81:969-977 pubmed publisher |
| Zhi E, Liang G, Li P, Chen H, Tian R, Xu P, et al. Seminal plasma miR-192a: a biomarker predicting successful resolution of nonobstructive azoospermia following varicocele repair. Asian J Androl. 2018;20:396-399 pubmed publisher |
| Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, et al. Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med. 2018;120:228-238 pubmed publisher |
| Tang X, Liu B, Wang X, Yu Q, Fang R. Epidermal Growth Factor, through Alleviating Oxidative Stress, Protect IPEC-J2 Cells from Lipopolysaccharides-Induced Apoptosis. Int J Mol Sci. 2018;19: pubmed publisher |
| Shi J, Li F, Yao X, Mou T, Xu Z, Han Z, et al. The HER4-YAP1 axis promotes trastuzumab resistance in HER2-positive gastric cancer by inducing epithelial and mesenchymal transition. Oncogene. 2018;37:3022-3038 pubmed publisher |
| Yang L, Guo Y, Huang M, Wu X, Li X, Chen G, et al. Thioredoxin-1 Protects Spinal Cord from Demyelination Induced by Methamphetamine through Suppressing Endoplasmic Reticulum Stress and Inflammation. Front Neurol. 2018;9:49 pubmed publisher |
| Sun Z, Zhang H, Wang X, Wang Q, Zhang C, Wang J, et al. TMCO1 is essential for ovarian follicle development by regulating ER Ca2+ store of granulosa cells. Cell Death Differ. 2018;25:1686-1701 pubmed publisher |
| Yang J, Zhang Y, Tong J, Lv H, Zhang C, Chen Z. Dysfunction of DNA damage-inducible transcript 4 in the decidua is relevant to the pathogenesis of preeclampsia. Biol Reprod. 2018;98:821-833 pubmed publisher |
| Zhang H, Liu P, Jiang C, Jin X, Liu R, Li S, et al. Notch signaling inhibitor DAPT provides protection against acute craniocerebral injury. PLoS ONE. 2018;13:e0193037 pubmed publisher |
| Che C, Liu J, Yang J, Ma L, Bai N, Zhang Q. Osteopontin is essential for IL-1β production and apoptosis in peri-implantitis. Clin Implant Dent Relat Res. 2018;20:384-392 pubmed publisher |
| Yin N, Wang Y, Lu X, Liu R, Zhang L, Zhao W, et al. hPMSC transplantation restoring ovarian function in premature ovarian failure mice is associated with change of Th17/Tc17 and Th17/Treg cell ratios through the PI3K/Akt signal pathway. Stem Cell Res Ther. 2018;9:37 pubmed publisher |
| Yang B, Song J, Sun H, Xing J, Yang Z, Wei C, et al. PSMB8 regulates glioma cell migration, proliferation, and apoptosis through modulating ERK1/2 and PI3K/AKT signaling pathways. Biomed Pharmacother. 2018;100:205-212 pubmed publisher |
| Zhang Y, Li H, Yang X, Jin G, Zhang Y. Cognitive-enhancing effect of polysaccharides from Flammulina velutipes on Alzheimer's disease by compatibilizing with ginsenosides. Int J Biol Macromol. 2018;112:788-795 pubmed publisher |
| Lian S, Wang D, Xu B, Guo W, Wang L, Li W, et al. Prenatal cold stress: Effect on maternal hippocampus and offspring behavior in rats. Behav Brain Res. 2018;346:1-10 pubmed publisher |
| Zhang J, Yuan J, Wang Q, Shao L, Liu S, Firestone R, et al. Experimental evidence of good efficacy and reduced toxicity with peptide-doxorubicin to treat gastric cancer. Oncotarget. 2018;9:1957-1968 pubmed publisher |
| Jia Y, Lu H, Peng Y, Zhang B, Gong X, Su J, et al. Oxyresveratrol prevents lipopolysaccharide/d-galactosamine-induced acute liver injury in mice. Int Immunopharmacol. 2018;56:105-112 pubmed publisher |
| Deng F, Peng L, Li Z, Tan G, Liang E, Chen S, et al. YAP triggers the Wnt/β-catenin signalling pathway and promotes enterocyte self-renewal, regeneration and tumorigenesis after DSS-induced injury. Cell Death Dis. 2018;9:153 pubmed publisher |
| Liu M, Li Y, Liang B, Li Z, Jiang Z, Chu C, et al. Hydrogen sulfide attenuates myocardial fibrosis in diabetic rats through the JAK/STAT signaling pathway. Int J Mol Med. 2018;41:1867-1876 pubmed publisher |
| Chen L, Liu L, Xie Z, Wang F, Sinkemani A, Zhang C, et al. Endoplasmic Reticulum Stress Facilitates the Survival and Proliferation of Nucleus Pulposus Cells in TNF-α Stimulus by Activating Unfolded Protein Response. DNA Cell Biol. 2018;37:347-358 pubmed publisher |
| Luo S, Pan Z, Liu S, Yuan S, Yan N. Sphingomyelin synthase 2 overexpression promotes cisplatin-induced apoptosis of HepG2 cells. Oncol Lett. 2018;15:483-488 pubmed publisher |
| Duan H, Wu Q, Yao X, Fan B, Shi H, Zhao C, et al. Nafamostat mesilate attenuates inflammation and apoptosis and promotes locomotor recovery after spinal cord injury. CNS Neurosci Ther. 2018;24:429-438 pubmed publisher |
| Cao Y, Chen Q, Wang Z, Yu T, Wu J, Jiang X, et al. PLK1 protects against sepsis-induced intestinal barrier dysfunction. Sci Rep. 2018;8:1055 pubmed publisher |
| Cao Y, Yu J, Liu T, Yang K, Yang L, Chen Q, et al. Plumbagin inhibits the proliferation and survival of esophageal cancer cells by blocking STAT3-PLK1-AKT signaling. Cell Death Dis. 2018;9:17 pubmed publisher |
| Liu D, Cheng Y, Cai R, Wang Bd W, Cui H, Liu M, et al. The enhancement of siPLK1 penetration across BBB and its anti glioblastoma activity in vivo by magnet and transferrin co-modified nanoparticle. Nanomedicine. 2018;14:991-1003 pubmed publisher |
| Wei J, Wu H, Zhang H, Li F, Chen S, Hou B, et al. Anthocyanins inhibit high glucose-induced renal tubular cell apoptosis caused by oxidative stress in db/db mice. Int J Mol Med. 2018;41:1608-1618 pubmed publisher |
| Zhou X, Yong L, Huang Y, Zhu S, Song X, Li B, et al. The protective effects of distal ischemic treatment on apoptosis and mitochondrial permeability in the hippocampus after cardiopulmonary resuscitation. J Cell Physiol. 2018;233:6902-6910 pubmed publisher |
| Min Q, Wang X, Zhang J, Chen Q, Li S, Liu X, et al. Exosomes derived from imatinib-resistant chronic myeloid leukemia cells mediate a horizontal transfer of drug-resistant trait by delivering miR-365. Exp Cell Res. 2018;362:386-393 pubmed publisher |
| Wang J, Tian L, Khan M, Zhang L, Chen Q, Zhao Y, et al. Ginsenoside Rg3 sensitizes hypoxic lung cancer cells to cisplatin via blocking of NF-κB mediated epithelial-mesenchymal transition and stemness. Cancer Lett. 2018;415:73-85 pubmed publisher |
| Hsieh C, Wang J, Chiu C, Liu C, Yao C, Fang K. A triazole-conjugated benzoxazone induces reactive oxygen species and promotes autophagic apoptosis in human lung cancer cells. Apoptosis. 2018;23:1-15 pubmed publisher |
| Luo J, Wang Z, Huang J, Yao Y, Sun Q, Wang J, et al. HOXC13 promotes proliferation of esophageal squamous cell carcinoma via repressing transcription of CASP3. Cancer Sci. 2018;109:317-329 pubmed publisher |
| Xiao Y, Tian C, Huang T, Han B, Wang M, Ma H, et al. 8-Cetylberberine inhibits growth of lung cancer in vitro and in vivo. Life Sci. 2018;192:259-269 pubmed publisher |
| Liu C, Xing J, Gao Y. UNBS5162 inhibits the proliferation of human A549 non-small-cell lung cancer cells by promoting apoptosis. Thorac Cancer. 2018;9:105-111 pubmed publisher |
| Zhou B, Wei C, Zhang S, Zhang Z, Gao H. Matrine reversed multidrug resistance of breast cancer MCF-7/ADR cells through PI3K/AKT signaling pathway. J Cell Biochem. 2018;119:3885-3891 pubmed publisher |
| Zeng Q, Liu J, Cao P, Li J, Liu X, Fan X, et al. Inhibition of REDD1 Sensitizes Bladder Urothelial Carcinoma to Paclitaxel by Inhibiting Autophagy. Clin Cancer Res. 2018;24:445-459 pubmed publisher |
| Wei P, Zheng Q, Liu H, Wan T, Zhou J, Li D, et al. Nicotine-Induced Neuroprotection against Cognitive Dysfunction after Partial Hepatectomy Involves Activation of BDNF/TrkB Signaling Pathway and Inhibition of NF-κB Signaling Pathway in Aged Rats. Nicotine Tob Res. 2018;20:515-522 pubmed publisher |
| Tang J, He A, Jia G, Liu G, Chen X, Cai J, et al. Protective Effect of Selenoprotein X Against Oxidative Stress-Induced Cell Apoptosis in Human Hepatocyte (LO2) Cells via the p38 Pathway. Biol Trace Elem Res. 2018;181:44-53 pubmed publisher |
| Yin S, Du W, Wang F, Han B, Cui Y, Yang D, et al. MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway. Cancer Biol Ther. 2018;19:260-270 pubmed publisher |
| Yang Y, Zhao J, Zhang J, Lei Y, Yuan F, Liu L, et al. Regulation of macrophage migration in ischemic mouse hearts via an AKT2/NBA1/SPK1 pathway. Oncotarget. 2017;8:115345-115359 pubmed publisher |
| Lian S, Guo J, Wang L, Li W, Wang J, Ji H, et al. Impact of prenatal cold stress on placental physiology, inflammatory response, and apoptosis in rats. Oncotarget. 2017;8:115304-115314 pubmed publisher |
| Zhang B, Liu Y, Liu D, Yang L. Targeting cleavage and polyadenylation specific factor 1 via shRNA inhibits cell proliferation in human ovarian cancer. J Biosci. 2017;42:417-425 pubmed |
| Gu Y, Yang X, Duan Z, Luo P, Shang J, Xiao W, et al. Inhibition of chemotherapy-induced apoptosis of testicular cells by squid ink polysaccharide. Exp Ther Med. 2017;14:5889-5895 pubmed publisher |
| Sun W, Yang J, Zhang Y, Xi Y, Wen X, Yuan D, et al. Exogenous H2S restores ischemic post-conditioning-induced cardioprotection through inhibiting endoplasmic reticulum stress in the aged cardiomyocytes. Cell Biosci. 2017;7:67 pubmed publisher |
| Yao X, Tang H, Ren Q, Zhao X, Zuo H, Li Z. Inhibited effects of CAPE-pNO2 on cervical carcinoma in vivo and in vitro and its detected metabolites. Oncotarget. 2017;8:94197-94209 pubmed publisher |
| Li J, Yang C, Zhang S, Liu S, Zhao L, Luo H, et al. Ginsenoside Rg1 inhibits inflammatory responses via modulation of the nuclear factor??B pathway and inhibition of inflammasome activation in alcoholic hepatitis. Int J Mol Med. 2017;: pubmed publisher |
| Ruibin J, Bo J, Danying W, Chihong Z, Jianguo F, Linhui G. Therapy Effects of Wogonin on Ovarian Cancer Cells. Biomed Res Int. 2017;2017:9381513 pubmed publisher |
| Wang B, Shen J, Wang J. UNBS5162 inhibits proliferation of human retinoblastoma cells by promoting cell apoptosis. Onco Targets Ther. 2017;10:5303-5309 pubmed publisher |
| Mehmood T, Maryam A, Tian X, Khan M, Ma T. Santamarine Inhibits NF-?B and STAT3 Activation and Induces Apoptosis in HepG2 Liver Cancer Cells via Oxidative Stress. J Cancer. 2017;8:3707-3717 pubmed publisher |
| Song L, Wang Z, Wang Y, Guo D, Yang J, Chen L, et al. Natural Cyclopeptide RA-XII, a New Autophagy Inhibitor, Suppresses Protective Autophagy for Enhancing Apoptosis through AMPK/mTOR/P70S6K Pathways in HepG2 Cells. Molecules. 2017;22: pubmed publisher |
| Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, et al. The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity. Sci Rep. 2017;7:15175 pubmed publisher |
| Guo Y, Peng Y, Gao D, Zhang M, Yang W, Linghu E, et al. Silencing HOXD10 by promoter region hypermethylation activates ERK signaling in hepatocellular carcinoma. Clin Epigenetics. 2017;9:116 pubmed publisher |
| Sun G, Lu Y, Li Y, Mao J, Zhang J, Jin Y, et al. miR-19a protects cardiomyocytes from hypoxia/reoxygenation-induced apoptosis via PTEN/PI3K/p-Akt pathway. Biosci Rep. 2017;37: pubmed publisher |
| Zong S, Liu T, Wan F, Chen P, Luo P, Xiao H. Endoplasmic Reticulum Stress Is Involved in Cochlear Cell Apoptosis in a Cisplatin-Induced Ototoxicity Rat Model. Audiol Neurootol. 2017;22:160-168 pubmed publisher |
| Gao G, Li Y, Zhai H, Bi J, Zhang F, Zhang X, et al. Humanin analogue, S14G-humanin, has neuroprotective effects against oxygen glucose deprivation/reoxygenation by reactivating Jak2/Stat3 signaling through the PI3K/AKT pathway. Exp Ther Med. 2017;14:3926-3934 pubmed publisher |
| Gao C, Zhou Y, Li H, Cong X, Jiang Z, Wang X, et al. Antitumor effects of baicalin on ovarian cancer cells through induction of cell apoptosis and inhibition of cell migration in vitro. Mol Med Rep. 2017;16:8729-8734 pubmed publisher |
| Jin E, Ren M, Liu W, Liang S, Hu Q, Gu Y, et al. Effect of Boron on Thymic Cytokine Expression, Hormone Secretion, Antioxidant Functions, Cell Proliferation, and Apoptosis Potential via the Extracellular Signal-Regulated Kinases 1 and 2 Signaling Pathway. J Agric Food Chem. 2017;65:11280-11291 pubmed publisher |
| Zhou H, Zheng L, Lu K, Gao Y, Guo L, Xu W, et al. Downregulation of Cohesin Loading Factor Nipped-B-Like Protein (NIPBL) Induces Cell Cycle Arrest, Apoptosis, and Autophagy of Breast Cancer Cell Lines. Med Sci Monit. 2017;23:4817-4825 pubmed |
| Sheng N, Yan L, You W, Tan G, Gong J, Chen H, et al. Knockdown of SLC39A7 inhibits cell growth and induces apoptosis in human colorectal cancer cells. Acta Biochim Biophys Sin (Shanghai). 2017;49:926-934 pubmed publisher |
| Yang F, Zhang L, Gao Z, Sun X, Yu M, Dong S, et al. Exogenous H2S Protects Against Diabetic Cardiomyopathy by Activating Autophagy via the AMPK/mTOR Pathway. Cell Physiol Biochem. 2017;43:1168-1187 pubmed publisher |
| Xu F, Li X, Liu L, Xiao X, Zhang L, Zhang S, et al. Attenuation of doxorubicin-induced cardiotoxicity by esculetin through modulation of Bmi-1 expression. Exp Ther Med. 2017;14:2216-2220 pubmed publisher |
| Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, et al. The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart. Chemosphere. 2017;189:489-497 pubmed publisher |
| Han J, Liu Y, Jiang Q, Xiao R. Cysteine-rich buccal gland protein suppressed the proliferation, migration and invasion of hela cells through akt pathway. IUBMB Life. 2017;69:856-866 pubmed publisher |
| Lin H, Ma X, Wang B, Zhao L, Liu J, Pu F, et al. Edaravone ameliorates compression-induced damage in rat nucleus pulposus cells. Life Sci. 2017;189:76-83 pubmed publisher |
| Wang Y, Jiang L, Yin Q, Liu H, Liu G, Zhu G, et al. The Targeted Antitumor Effects of C- PC/CMC-CD59sp Nanoparticles on HeLa Cells in Vitro and in Vivo. J Cancer. 2017;8:3001-3013 pubmed publisher |
| Wang J, Li D, Zhuang Y, Fu J, Li X, Shi Q, et al. Exosomes derived from bone marrow stromal cells decrease the sensitivity of leukemic cells to etoposide. Oncol Lett. 2017;14:3082-3088 pubmed publisher |
| Wang J, Hsieh C, Liu C, Lin K, Wu P, Chen K, et al. Reactive oxygen species-driven mitochondrial injury induces apoptosis by teroxirone in human non-small cell lung cancer cells. Oncol Lett. 2017;14:3503-3509 pubmed publisher |
| Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, et al. Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells. Cell Biol Int. 2017;41:1367-1378 pubmed publisher |
| Liu Y, Lei J, Tang L, Peng Y, Au C, Chen Y, et al. Studies on the cytotoxicity and anticancer performance of heterocyclic hypervalent organobismuth(III) compounds. Eur J Med Chem. 2017;139:826-835 pubmed publisher |
| Chen L, Ren Z, Wei X, Wang S, Wang Y, Cheng Y, et al. Losartan protects against cerebral ischemia/reperfusion-induced apoptosis through β-arrestin1-mediated phosphorylation of Akt. Eur J Pharmacol. 2017;815:98-108 pubmed publisher |
| Zhao Y, Jing Z, Lv J, Zhang Z, Lin J, Cao X, et al. Berberine activates caspase-9/cytochrome c-mediated apoptosis to suppress triple-negative breast cancer cells in vitro and in vivo. Biomed Pharmacother. 2017;95:18-24 pubmed publisher |
| Tang H, Yao X, Yao C, Zhao X, Zuo H, Li Z. Anti-colon cancer effect of caffeic acid p-nitro-phenethyl ester in vitro and in vivo and detection of its metabolites. Sci Rep. 2017;7:7599 pubmed publisher |
| Duan L, Deng L, Wang D, Ma S, Li C, Zhao D. Treatment mechanism of matrine in combination with irinotecan for colon cancer. Oncol Lett. 2017;14:2300-2304 pubmed publisher |
| Chen F, Zhang H, Wang Z, Ding W, Zeng Q, Liu W, et al. Adipose-Derived Stem Cell-Derived Exosomes Ameliorate Erectile Dysfunction in a Rat Model of Type 2 Diabetes. J Sex Med. 2017;14:1084-1094 pubmed publisher |
| Ni Y, Hsieh C, Kim S, Wang J, Su C, Yao C, et al. A potent indolylquinoline alleviates growth of human lung cancer cell tumorspheres. Apoptosis. 2017;22:1235-1245 pubmed publisher |
| Gu R, Tang W, Lei B, Ding X, Jiang C, Xu G. Glucocorticoid-Induced Leucine Zipper Protects the Retina From Light-Induced Retinal Degeneration by Inducing Bcl-xL in Rats. Invest Ophthalmol Vis Sci. 2017;58:3656-3668 pubmed publisher |
| Zhou X, Liu Y, Huang Y, Zhu S, Zhu J, Wang R. Hypertonic saline infusion suppresses apoptosis of hippocampal cells in a rat model of cardiopulmonary resuscitation. Sci Rep. 2017;7:5783 pubmed publisher |
| Feng J, Zhang Q, Mo W, Wu L, Li S, Li J, et al. Salidroside pretreatment attenuates apoptosis and autophagy during hepatic ischemia-reperfusion injury by inhibiting the mitogen-activated protein kinase pathway in mice. Drug Des Devel Ther. 2017;11:1989-2006 pubmed publisher |
| Gao G, Fan H, Zhang X, Zhang F, Wu H, Qi F, et al. Neuroprotective effect of G14-humanin on global cerebral ischemia/reperfusion by activation of SOCS3 - STAT3 - MCL-1 signal transduction pathway in rats. Neurol Res. 2017;39:895-903 pubmed publisher |
| Zhang W, Xiao D, Shan L, Zhao J, Mao Q, Xia H. Generation of apoptosis-resistant HEK293 cells with CRISPR/Cas mediated quadruple gene knockout for improved protein and virus production. Biotechnol Bioeng. 2017;114:2539-2549 pubmed publisher |
| Lin K, Yang R, Zheng Z, Zhou Y, Geng Y, Hu Y, et al. Sulforaphane-cysteine-induced apoptosis via phosphorylated ERK1/2-mediated maspin pathway in human non-small cell lung cancer cells. Cell Death Discov. 2017;3:17025 pubmed publisher |
| Yang W, Yang S, Zhang M, Gao D, He T, Guo M. ZNF545 suppresses human hepatocellular carcinoma growth by inhibiting NF-kB signaling. Genes Cancer. 2017;8:528-535 pubmed publisher |
| Gao X, Xie G, Liu L, Fu Z, Zhang Z, Teng L. Sesamol attenuates oxidative stress, apoptosis and inflammation in focal cerebral ischemia/reperfusion injury. Exp Ther Med. 2017;14:841-847 pubmed publisher |
| Zhao W, Chen S, Wang J, Xu C, Zhao M, Dong H, et al. Establishment of an ideal time window model in hypothermic-targeted temperature management after traumatic brain injury in rats. Brain Res. 2017;1669:141-149 pubmed publisher |
| Su W, Lin Y, Yu X, Wang Y, Lin X, Su Q, et al. Mitochondria-Associated Apoptosis in Human Melanoma Cells Induced by Cardanol Monoene from Cashew Nut Shell Liquid. J Agric Food Chem. 2017;65:5620-5631 pubmed publisher |
| Uslusoy F, Naziroglu M, Ciğ B. Inhibition of the TRPM2 and TRPV1 Channels through Hypericum perforatum in Sciatic Nerve Injury-induced Rats Demonstrates their Key Role in Apoptosis and Mitochondrial Oxidative Stress of Sciatic Nerve and Dorsal Root Ganglion. Front Physiol. 2017;8:335 pubmed publisher |
| Lu S, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. The osteogenesis-promoting effects of alpha-lipoic acid against glucocorticoid-induced osteoporosis through the NOX4, NF-kappaB, JNK and PI3K/AKT pathways. Sci Rep. 2017;7:3331 pubmed publisher |
| Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, et al. Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate. J Cell Mol Med. 2017;21:3190-3203 pubmed publisher |
| Chen Y, Li Y, Xu H, Li G, Ma Y, Pang Y. MORIN MITIGATES OXIDATIVE STRESS, APOPTOSIS AND INFLAMMATION IN CEREBRAL ISCHEMIC RATS. Afr J Tradit Complement Altern Med. 2017;14:348-355 pubmed publisher |
| Fang S, Qiu J, Wu Z, Bai T, Guo W. Down-regulation of UBC9 increases the sensitivity of hepatocellular carcinoma to doxorubicin. Oncotarget. 2017;8:49783-49795 pubmed publisher |
| Öz A, Celik O. Curcumin inhibits oxidative stress-induced TRPM2 channel activation, calcium ion entry and apoptosis values in SH-SY5Y neuroblastoma cells: Involvement of transfection procedure. Mol Membr Biol. 2016;33:76-88 pubmed publisher |
| Cai Z, Zou Y, Hu H, Lu C, Sun W, Jiang L, et al. RIZ1 negatively regulates ubiquitin-conjugating enzyme E2C/UbcH10 via targeting c-Myc in meningioma. Am J Transl Res. 2017;9:2645-2655 pubmed |
| Xie X, Cao Y, Yang X, Xu Q, Wei W, Wang M. Relaxin Attenuates Contrast-Induced Human Proximal Tubular Epithelial Cell Apoptosis by Activation of the PI3K/Akt Signaling Pathway In Vitro. Biomed Res Int. 2017;2017:2869405 pubmed publisher |
| Cai R, Liu D, Cui H, Cheng Y, Liu M, Zhang B, et al. Charge reversible calcium phosphate lipid hybrid nanoparticle for siRNA delivery. Oncotarget. 2017;8:42772-42788 pubmed publisher |
| Wang E, Zou B, Shi L, Du L, Zhu Y, Jiang Y, et al. 7-O-geranylquercetin-induced autophagy contributes to apoptosis via ROS generation in human non-small cell lung cancer cells. Life Sci. 2017;180:102-113 pubmed publisher |
| Li Y, Liu H, Liang Y, Peng P, Ma X, Zhang X. DKK3 regulates cell proliferation, apoptosis and collagen synthesis in keloid fibroblasts via TGF-β1/Smad signaling pathway. Biomed Pharmacother. 2017;91:174-180 pubmed publisher |
| Wang Y, Yan J, Zou X, Guo K, Zhao Y, Meng C, et al. Bone marrow mesenchymal stem cells repair cadmium-induced rat testis injury by inhibiting mitochondrial apoptosis. Chem Biol Interact. 2017;271:39-47 pubmed publisher |
| Yao C, Cao X, Fu Z, Tian J, Dong W, Xu J, et al. Boschniakia Rossica Polysaccharide Triggers Laryngeal Carcinoma Cell Apoptosis by Regulating Expression of Bcl-2, Caspase-3, and P53. Med Sci Monit. 2017;23:2059-2064 pubmed |
| Yang Y, Gong X, Huang L, Wang Z, Wan R, Zhang P, et al. Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice. Oncotarget. 2017;8:30723-30733 pubmed publisher |
| Ma H, Li L, Dou G, Wang C, Li J, He H, et al. Z-ligustilide restores tamoxifen sensitivity of ERa negative breast cancer cells by reversing MTA1/IFI16/HDACs complex mediated epigenetic repression of ERa. Oncotarget. 2017;8:29328-29345 pubmed publisher |
| Wang Q, Ding W, Ding Y, Ma J, Qian Z, Shao J, et al. Homoharringtonine suppresses imatinib resistance via the Bcl-6/p53 pathway in chronic myeloid leukemia cell lines. Oncotarget. 2017;8:37594-37604 pubmed publisher |
| Xie X, Zhao N, Xu Q, Yang X, Xia W, Chen Q, et al. Relaxin attenuates aristolochic acid induced human tubular epithelial cell apoptosis in vitro by activation of the PI3K/Akt signaling pathway. Apoptosis. 2017;22:769-776 pubmed publisher |
| Huang W, Ren C, Huang G, Liu J, Liu W, Wang L, et al. Inhibition of store-operated Ca2+ entry counteracts the apoptosis of nasopharyngeal carcinoma cells induced by sodium butyrate. Oncol Lett. 2017;13:921-929 pubmed publisher |
| Wu D, Luo N, Wang L, Zhao Z, Bu H, Xu G, et al. Hydrogen sulfide ameliorates chronic renal failure in rats by inhibiting apoptosis and inflammation through ROS/MAPK and NF-?B signaling pathways. Sci Rep. 2017;7:455 pubmed publisher |
| Wang X, Cao W, Zhang J, Yan M, Xu Q, Wu X, et al. A covalently bound inhibitor triggers EZH2 degradation through CHIP-mediated ubiquitination. EMBO J. 2017;36:1243-1260 pubmed publisher |
| Liu S, Sun Z, Chu P, Li H, Ahsan A, Zhou Z, et al. EGCG protects against homocysteine-induced human umbilical vein endothelial cells apoptosis by modulating mitochondrial-dependent apoptotic signaling and PI3K/Akt/eNOS signaling pathways. Apoptosis. 2017;22:672-680 pubmed publisher |
| Liu L, Bai X, Gao Y, Wu Q, Ren Z, Li Q, et al. PCSK9 Promotes oxLDL-Induced PC12 Cell Apoptosis Through the Bcl-2/Bax-Caspase 9/3 Signaling Pathway. J Alzheimers Dis. 2017;57:723-734 pubmed publisher |
| Ying C, Liu T, Ling H, Cheng M, Zhou X, Wang S, et al. Glucose variability aggravates cardiac fibrosis by altering AKT signalling path. Diab Vasc Dis Res. 2017;14:327-335 pubmed publisher |
| Wei H, Gao Z, Zheng L, Zhang C, Liu Z, Yang Y, et al. Protective Effects of Fucoidan on A?25-35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice. Mar Drugs. 2017;15: pubmed publisher |
| Gong X, Yang Y, Huang L, Zhang Q, Wan R, Zhang P, et al. Antioxidation, anti-inflammation and anti-apoptosis by paeonol in LPS/d-GalN-induced acute liver failure in mice. Int Immunopharmacol. 2017;46:124-132 pubmed publisher |
| Huang Z, Yang G, Shen T, Wang X, Li H, Ren D. Dehydrobruceine B enhances the cisplatin-induced cytotoxicity through regulation of the mitochondrial apoptotic pathway in lung cancer A549 cells. Biomed Pharmacother. 2017;89:623-631 pubmed publisher |
| Wang H, Xu Y, Wang M, Cheng C, Bian R, Yuan H, et al. Protective effect of naringin against the LPS-induced apoptosis of PC12 cells: Implications for the treatment of neurodegenerative disorders. Int J Mol Med. 2017;39:819-830 pubmed publisher |
| Liu C, Hao Y, Yin F, Zhang Y, Liu J. Geniposide protects pancreatic ? cells from high glucose-mediated injury by activation of AMP-activated protein kinase. Cell Biol Int. 2017;41:544-554 pubmed publisher |
| Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, et al. Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation. Drug Des Devel Ther. 2017;11:431-439 pubmed publisher |
| Feng D, Yao J, Wang G, Li Z, Zu G, Li Y, et al. Inhibition of p66Shc-mediated mitochondrial apoptosis via targeting prolyl-isomerase Pin1 attenuates intestinal ischemia/reperfusion injury in rats. Clin Sci (Lond). 2017;131:759-773 pubmed publisher |
| Yin K, Zhu R, Wang S, Zhao R. Low-Level Laser Effect on Proliferation, Migration, and Antiapoptosis of Mesenchymal Stem Cells. Stem Cells Dev. 2017;26:762-775 pubmed publisher |
| Huang T, Xiao Y, Yi L, Li L, Wang M, Tian C, et al. Coptisine from Rhizoma Coptidis Suppresses HCT-116 Cells-related Tumor Growth in vitro and in vivo. Sci Rep. 2017;7:38524 pubmed publisher |
| Dai X, Dong M, Yu H, Xie Y, Yu Y, Cao Y, et al. Knockdown of TCTN1 Strongly Decreases Growth of Human Colon Cancer Cells. Med Sci Monit. 2017;23:452-461 pubmed |
| Yan P, Xu J, Zeng Y, Dong G, Cao H, Zheng M, et al. Long-term effects of repeated superovulation on the uterus and mammary gland in rhesus monkeys. J Assist Reprod Genet. 2017;34:535-545 pubmed publisher |
| Jin E, Li S, Ren M, Hu Q, Gu Y, Li K. Boron Affects Immune Function Through Modulation of Splenic T Lymphocyte Subsets, Cytokine Secretion, and Lymphocyte Proliferation and Apoptosis in Rats. Biol Trace Elem Res. 2017;178:261-275 pubmed publisher |
| Tan M, Cao X, Li P, Zhai Y, Zhou Y, Liu Y, et al. Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide. Biotechnol Appl Biochem. 2017;64:918-926 pubmed publisher |
| Zhu Y, Jiang Y, Shi L, Du L, Xu X, Wang E, et al. 7-O-Geranylquercetin induces apoptosis in gastric cancer cells via ROS-MAPK mediated mitochondrial signaling pathway activation. Biomed Pharmacother. 2017;87:527-538 pubmed publisher |
| Wang X, Sun Y, Zhao C, Qu F, Zhao Y. 12-Chloracetyl-PPD, a novel dammarane derivative, shows anti-cancer activity via delay the progression of cell cycle G2/M phase and reactive oxygen species-mediate cell apoptosis. Eur J Pharmacol. 2017;798:49-56 pubmed publisher |
| Zhao X, Wu Q, Peng J, Pan L, Ren Z, Liu H, et al. Hyperlipidemia-induced apoptosis of hippocampal neurons in apoE(-/-) mice may be associated with increased PCSK9 expression. Mol Med Rep. 2017;15:712-718 pubmed publisher |
| Yang F, Yu X, Li T, Wu J, Zhao Y, Liu J, et al. Exogenous H2S regulates endoplasmic reticulum-mitochondria cross-talk to inhibit apoptotic pathways in STZ-induced type I diabetes. Am J Physiol Endocrinol Metab. 2017;312:E190-E203 pubmed publisher |
| Liu Y, Pu Y, Li D, Zhou L, Wan L. Azithromycin ameliorates airway remodeling via inhibiting airway epithelium apoptosis. Life Sci. 2017;170:1-8 pubmed publisher |
| Tang Q, Ji F, Sun W, Wang J, Guo J, Guo L, et al. Combination of baicalein and 10-hydroxy camptothecin exerts remarkable synergetic anti-cancer effects. Phytomedicine. 2016;23:1778-1786 pubmed publisher |
| Yang J, Zhang K, Wu J, Shi J, Xue J, Li J, et al. Wnt5a Increases Properties of Lung Cancer Stem Cells and Resistance to Cisplatin through Activation of Wnt5a/PKC Signaling Pathway. Stem Cells Int. 2016;2016:1690896 pubmed |
| Zhou Y, Yuan H, Cui L, Ansari A, Xiao K, Luo Y, et al. Effects of visfatin on the apoptosis of intestinal mucosal cells in immunological stressed rats. Acta Histochem. 2017;119:26-31 pubmed publisher |
| Zhao S, Li L, Wang S, Yu C, Xiao B, Lin L, et al. H2O2 treatment or serum deprivation induces autophagy and apoptosis in naked mole-rat skin fibroblasts by inhibiting the PI3K/Akt signaling pathway. Oncotarget. 2016;7:84839-84850 pubmed publisher |
| Li Y, Li P, Zhu R, Luo C, Li H, Hu S, et al. Multifunctional Gold Nanoclusters-Based Nanosurface Energy Transfer Probe for Real-Time Monitoring of Cell Apoptosis and Self-Evaluating of Pro-Apoptotic Theranostics. Anal Chem. 2016;88:11184-11192 pubmed |
| Chen G, Song X, Wang B, You G, Zhao J, Xia S, et al. Carboxyfullerene nanoparticles alleviate acute hepatic injury in severe hemorrhagic shock. Biomaterials. 2017;112:72-81 pubmed publisher |
| Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, et al. Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro. Int Immunopharmacol. 2016;40:400-409 pubmed publisher |
| Wang Y, Zhang X, Xie W, Zheng Y, Cao J, Cao P, et al. The Growth of SGC-7901 Tumor Xenografts Was Suppressed by Chinese Bayberry Anthocyanin Extract through Upregulating KLF6 Gene Expression. Nutrients. 2016;8: pubmed |
| Yan X, Yang W, Shao Z, Yang S, Liu X. Triggering of apoptosis in osteosarcoma cells by graphene/single-walled carbon nanotube hybrids via the ROS-mediated mitochondrial pathway. J Biomed Mater Res A. 2017;105:443-453 pubmed publisher |
| Zeng J, Song F, Yang Y, Ma C, Deng G, Li Y, et al. The Generation and Characterization of Recombinant Protein and Antibodies of Clostridium perfringens Beta2 Toxin. J Immunol Res. 2016;2016:5708468 pubmed |
| Mao Y, Wang J, Yu F, Li Z, Li H, Guo C, et al. Ghrelin protects against palmitic acid or lipopolysaccharide-induced hepatocyte apoptosis through inhibition of MAPKs/iNOS and restoration of Akt/eNOS pathways. Biomed Pharmacother. 2016;84:305-313 pubmed publisher |
| Li Y, Jiang Z, Xue D, Deng G, Li M, Liu X, et al. Mycoplasma ovipneumoniae induces sheep airway epithelial cell apoptosis through an ERK signalling-mediated mitochondria pathway. BMC Microbiol. 2016;16:222 pubmed |
| Song Z, Chen C, Liu J, Wen X, Sun H, Yuan H. Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis. Eur J Med Chem. 2016;124:809-819 pubmed publisher |
| Dia V, Krishnan H. BG-4, a novel anticancer peptide from bitter gourd (Momordica charantia), promotes apoptosis in human colon cancer cells. Sci Rep. 2016;6:33532 pubmed publisher |
| Mehmood T, Maryam A, Zhang H, Li Y, Khan M, Ma T. Deoxyelephantopin induces apoptosis in HepG2 cells via oxidative stress, NF-?B inhibition and mitochondrial dysfunction. Biofactors. 2017;43:63-72 pubmed publisher |
| Chu P, Han G, Ahsan A, Sun Z, Liu S, Zhang Z, et al. Phosphocreatine protects endothelial cells from Methylglyoxal induced oxidative stress and apoptosis via the regulation of PI3K/Akt/eNOS and NF-?B pathway. Vascul Pharmacol. 2017;91:26-35 pubmed publisher |
| Tang D, Wang C, Gao Y, Pu J, Long J, Xu W. Deep hypothermia-enhanced autophagy protects PC12 cells against oxygen glucose deprivation via a mitochondrial pathway. Neurosci Lett. 2016;632:79-85 pubmed publisher |
| Jiang G, Liu J, Ren B, Tang Y, Owusu L, Li M, et al. Anti-tumor effects of osthole on ovarian cancer cells in vitro. J Ethnopharmacol. 2016;193:368-376 pubmed publisher |
| Zhang X, Huang Z, Hu Y, Liu L. Knockdown of Myosin 6 inhibits proliferation of oral squamous cell carcinoma cells. J Oral Pathol Med. 2016;45:740-745 pubmed publisher |
| Zou M, Wang F, Jiang A, Xia A, Kong S, Gong C, et al. MicroRNA-3178 ameliorates inflammation and gastric carcinogenesis promoted by Helicobacter pylori new toxin, Tip-?, by targeting TRAF3. Helicobacter. 2017;22: pubmed publisher |
| Liu G, Wang J, Deng X, Ma P, Li F, Peng X, et al. The Anticonvulsant and Neuroprotective Effects of Oxysophocarpine on Pilocarpine-Induced Convulsions in Adult Male Mice. Cell Mol Neurobiol. 2017;37:339-349 pubmed publisher |
| Tang Q, Ji F, Guo J, Wang J, Li Y, Bao Y. Directional modification of chrysin for exerting apoptosis and enhancing significantly anti-cancer effects of 10-hydroxy camptothecin. Biomed Pharmacother. 2016;82:693-703 pubmed publisher |
| Yuan S, Wen J, Cheng J, Shen W, Zhou S, Yan W, et al. Age-associated up-regulation of EGR1 promotes granulosa cell apoptosis during follicle atresia in mice through the NF-κB pathway. Cell Cycle. 2016;15:2895-2905 pubmed |
| Khan S, Zhao D, Shah S, Hassan M, Zhu T, Song Z, et al. Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells. Cell Mol Neurobiol. 2017;37:717-728 pubmed publisher |
| Wang B, Zhang Y, Cao W, Wei X, Chen J, Ying W. SIRT2 Plays Significant Roles in Lipopolysaccharides-Induced Neuroinflammation and Brain Injury in Mice. Neurochem Res. 2016;41:2490-500 pubmed publisher |
| Wan X, Pu H, Huang W, Yang S, Zhang Y, Kong Z, et al. Androgen-induced miR-135a acts as a tumor suppressor through downregulating RBAK and MMP11, and mediates resistance to androgen deprivation therapy. Oncotarget. 2016;7:51284-51300 pubmed publisher |
| Zhang W, Yin L, Tao X, Xu L, Zheng L, Han X, et al. Dioscin alleviates dimethylnitrosamine-induced acute liver injury through regulating apoptosis, oxidative stress and inflammation. Environ Toxicol Pharmacol. 2016;45:193-201 pubmed publisher |
| Zhao X, Tao X, Xu L, Yin L, Qi Y, Xu Y, et al. Dioscin Induces Apoptosis in Human Cervical Carcinoma HeLa and SiHa Cells through ROS-Mediated DNA Damage and the Mitochondrial Signaling Pathway. Molecules. 2016;21: pubmed publisher |
| Zou M, Duan Y, Wang P, Gao R, Chen X, Ou Y, et al. DYT-40, a novel synthetic 2-styryl-5-nitroimidazole derivative, blocks malignant glioblastoma growth and invasion by inhibiting AEG-1 and NF-κB signaling pathways. Sci Rep. 2016;6:27331 pubmed publisher |
| Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, et al. Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k. Chem Res Toxicol. 2016;29:1160-71 pubmed publisher |
| Zhang Y, Cheng Z, Wang C, Ma H, Meng W, Zhao Q. Neuroprotective Effects of Kukoamine a against Radiation-induced Rat Brain Injury through Inhibition of Oxidative Stress and Neuronal Apoptosis. Neurochem Res. 2016;41:2549-2558 pubmed |
| Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, et al. Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway. Cell Biosci. 2016;6:33 pubmed publisher |
| Lu J, Zhang Q, Tan D, Luo W, Zhao H, Ma J, et al. GABA A receptor ? subunit promotes apoptosis of HTR-8/SVneo trophoblastic cells: Implications in preeclampsia. Int J Mol Med. 2016;38:105-12 pubmed publisher |
| Wang J, Chen X, Wang F, Zhang J, Li P, Li Z, et al. OFD1, as a Ciliary Protein, Exhibits Neuroprotective Function in Photoreceptor Degeneration Models. PLoS ONE. 2016;11:e0155860 pubmed publisher |
| Geng J, Fan F, He S, Liu Y, Meng Y, Tian H, et al. The effects of the 5-HT2A receptor antagonist sarpogrelate hydrochloride on chronic hypoxic pulmonary hypertension in rats. Exp Lung Res. 2016;42:190-8 pubmed publisher |
| Hu Z, Yang B, Mo X, Zhou F. HspB8 mediates neuroprotection against OGD/R in N2A cells through the phosphoinositide 3-kinase/Akt pathway. Brain Res. 2016;1644:15-21 pubmed publisher |
| Zhao Y, Jing Z, Li Y, Mao W. Berberine in combination with cisplatin suppresses breast cancer cell growth through induction of DNA breaks and caspase-3-dependent apoptosis. Oncol Rep. 2016;36:567-72 pubmed publisher |
| Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu K, et al. Alpha-lipoic acid defends homocysteine-induced endoplasmic reticulum and oxidative stress in HAECs. Biomed Pharmacother. 2016;80:63-72 pubmed publisher |
| Shi Z, Liu Y, Dong L, Zhang B, Zhao M, Liu W, et al. Cortistatin Improves Cardiac Function After Acute Myocardial Infarction in Rats by Suppressing Myocardial Apoptosis and Endoplasmic Reticulum Stress. J Cardiovasc Pharmacol Ther. 2017;22:83-93 pubmed publisher |
| Feng G, Li J, Zheng M, Yang Z, Liu Y, Zhang S, et al. Hepatitis B virus X protein up-regulates C4b-binding protein ? through activating transcription factor Sp1 in protection of hepatoma cells from complement attack. Oncotarget. 2016;7:28013-26 pubmed publisher |
| Wang Z, Du T, Dong X, Li Z, Wu G, Zhang R. Autophagy inhibition facilitates erlotinib cytotoxicity in lung cancer cells through modulation of endoplasmic reticulum stress. Int J Oncol. 2016;48:2558-66 pubmed publisher |
| Sun Q, Nie S, Wang L, Yang F, Meng Z, Xiao H, et al. Factors that Affect Pancreatic Islet Cell Autophagy in Adult Rats: Evaluation of a Calorie-Restricted Diet and a High-Fat Diet. PLoS ONE. 2016;11:e0151104 pubmed publisher |
| Zhao L, Wen Q, Yang G, Huang Z, Shen T, Li H, et al. Apoptosis induction of dehydrobruceine B on two kinds of human lung cancer cell lines through mitochondrial-dependent pathway. Phytomedicine. 2016;23:114-22 pubmed publisher |
| Wang C, Shi Y, Tang M, Zhang X, Gu Y, Liang X, et al. Isoquercetin Ameliorates Cerebral Impairment in Focal Ischemia Through Anti-Oxidative, Anti-Inflammatory, and Anti-Apoptotic Effects in Primary Culture of Rat Hippocampal Neurons and Hippocampal CA1 Region of Rats. Mol Neurobiol. 2017;54:2126-2142 pubmed publisher |
| Wang X, Tian J, Yong K, Zhu X, Lin M, Jiang W, et al. Immunotoxicity assessment of CdSe/ZnS quantum dots in macrophages, lymphocytes and BALB/c mice. J Nanobiotechnology. 2016;14:10 pubmed publisher |
| Yu Y, Xu X, Liu L, Mao S, Feng T, Lu Y, et al. Progranulin deficiency leads to severe inflammation, lung injury and cell death in a mouse model of endotoxic shock. J Cell Mol Med. 2016;20:506-17 pubmed publisher |
| Zhu X, Zhang Y, Li Q, Yang L, Zhang N, Ma S, et al. β-Carotene Induces Apoptosis in Human Esophageal Squamous Cell Carcinoma Cell Lines via the Cav-1/AKT/NF-κB Signaling Pathway. J Biochem Mol Toxicol. 2016;30:148-57 pubmed publisher |
| Gao L, Xu Z, Wang Y, Sun B, Song Z, Yang B, et al. Anticancer effect of SZC017, a novel derivative of oleanolic acid, on human gastric cancer cells. Oncol Rep. 2016;35:1101-8 pubmed publisher |
| Sun Z, Lan X, Ahsan A, Xi Y, Liu S, Zhang Z, et al. Phosphocreatine protects against LPS-induced human umbilical vein endothelial cell apoptosis by regulating mitochondrial oxidative phosphorylation. Apoptosis. 2016;21:283-97 pubmed publisher |
| Zhao M, Fan J, Liu Y, Yu Y, Xu J, Wen Q, et al. Oncogenic role of the TP53-induced glycolysis and apoptosis regulator in nasopharyngeal carcinoma through NF-κB pathway modulation. Int J Oncol. 2016;48:756-64 pubmed publisher |
| Huang M, Xu A, Wu X, Zhang Y, Guo Y, Guo F, et al. Japanese encephalitis virus induces apoptosis by the IRE1/JNK pathway of ER stress response in BHK-21 cells. Arch Virol. 2016;161:699-703 pubmed publisher |
| Cui X, Li S, Li T, Peng H, Jin T, Zhang S, et al. Targeting oncogenic PLCE1 by miR-145 impairs tumor proliferation and metastasis of esophageal squamous cell carcinoma. Oncotarget. 2016;7:1777-95 pubmed publisher |
| Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, et al. SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells. Chem Biol Interact. 2016;244:94-104 pubmed publisher |
| Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, et al. Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. Biol Reprod. 2016;94:31 pubmed publisher |
| Xia Z, Li Z, Zhang M, Sun L, Zhang Q, Qiu X. CARMA3 regulates the invasion, migration, and apoptosis of non-small cell lung cancer cells by activating NF-кB and suppressing the P38 MAPK signaling pathway. Exp Mol Pathol. 2016;100:353-60 pubmed publisher |
| Song X, Li L, Shi Q, Lehmler H, Fu J, Su C, et al. Polychlorinated Biphenyl Quinone Metabolite Promotes p53-Dependent DNA Damage Checkpoint Activation, S-Phase Cycle Arrest and Extrinsic Apoptosis in Human Liver Hepatocellular Carcinoma HepG2 Cells. Chem Res Toxicol. 2015;28:2160-9 pubmed publisher |
| Mao Y, Wang J, Yu F, Cheng J, Li H, Guo C, et al. Ghrelin reduces liver impairment in a model of concanavalin A-induced acute hepatitis in mice. Drug Des Devel Ther. 2015;9:5385-96 pubmed publisher |
| Zhao C, Su G, Wang X, Zhang X, Guo S, Zhao Y. Antitumor activity of ginseng sapogenins, 25-OH-PPD and 25-OCH3-PPD, on gastric cancer cells. Biotechnol Lett. 2016;38:43-50 pubmed publisher |
| Gao L, Wang Y, Xu Z, Li X, Wu J, Liu S, et al. SZC017, a novel oleanolic acid derivative, induces apoptosis and autophagy in human breast cancer cells. Apoptosis. 2015;20:1636-50 pubmed publisher |
| Ahsan A, Han G, Pan J, Liu S, Padhiar A, Chu P, et al. Phosphocreatine protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway. Apoptosis. 2015;20:1563-76 pubmed publisher |
| Liang Z, Yi Y, Guo Y, Wang R, Hu Q, Xiong X. Inhibition of migration and induction of apoptosis in LoVo human colon cancer cells by polysaccharides from Ganoderma lucidum. Mol Med Rep. 2015;12:7629-36 pubmed publisher |
| Ma Z, Hou T, Shi W, Liu W, He H. Inhibition of Hepatocyte Apoptosis: An Important Mechanism of Corn Peptides Attenuating Liver Injury Induced by Ethanol. Int J Mol Sci. 2015;16:22062-80 pubmed publisher |
| Shi Q, Song X, Fu J, Su C, Xia X, Song E, et al. Artificial sweetener neohesperidin dihydrochalcone showed antioxidative, anti-inflammatory and anti-apoptosis effects against paraquat-induced liver injury in mice. Int Immunopharmacol. 2015;29:722-729 pubmed publisher |
| Gu A, Jie Y, Sun L, Zhao S, E M, You Q. RhNRG-1β Protects the Myocardium against Irradiation-Induced Damage via the ErbB2-ERK-SIRT1 Signaling Pathway. PLoS ONE. 2015;10:e0137337 pubmed publisher |
| Qin C, Song X, Chen Z, Ren X, Xu K, Jing H, et al. XRCC2 as a predictive biomarker for radioresistance in locally advanced rectal cancer patients undergoing preoperative radiotherapy. Oncotarget. 2015;6:32193-204 pubmed publisher |
| Wang Z, Zhao Z, Lu J, Chen Z, Mao A, Teng G, et al. A comparison of the biological effects of 125I seeds continuous low-dose-rate radiation and 60Co high-dose-rate gamma radiation on non-small cell lung cancer cells. PLoS ONE. 2015;10:e0133728 pubmed publisher |
| Wei P, Liu Q, Li D, Zheng Q, Zhou J, Li J. Acute nicotine treatment attenuates lipopolysaccharide-induced cognitive dysfunction by increasing BDNF expression and inhibiting neuroinflammation in the rat hippocampus. Neurosci Lett. 2015;604:161-6 pubmed publisher |
| Peng X, Zhang Y, Wang J, Ji Q. Ethylacetate extract from Tetrastigma hemsleyanum induces apoptosis via the mitochondrial caspase-dependent intrinsic pathway in HepG2 cells. Tumour Biol. 2016;37:865-76 pubmed publisher |
| Zhang C, Zhang J, Li X, Sun N, Yu R, Zhao B, et al. Huaier Aqueous Extract Induces Hepatocellular Carcinoma Cells Arrest in S Phase via JNK Signaling Pathway. Evid Based Complement Alternat Med. 2015;2015:171356 pubmed publisher |
| Zhang H, Xue J, Zhang Z, Kong H, Liu A, Li S, et al. Cold-inducible RNA-binding protein inhibits neuron apoptosis through the suppression of mitochondrial apoptosis. Brain Res. 2015;1622:474-83 pubmed publisher |
| Zhao P, Zhou R, Zhu X, Hao Y, Li N, Wang J, et al. Matrine attenuates focal cerebral ischemic injury by improving antioxidant activity and inhibiting apoptosis in mice. Int J Mol Med. 2015;36:633-44 pubmed publisher |
| Jin Y, Cao B, Zhang M, Zhan Q, Herman J, Yu M, et al. RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker. Genes Cancer. 2015;6:231-40 pubmed |
| Zhao P, Zhou R, Li H, Yao W, Qiao H, Wang S, et al. Oxymatrine attenuated hypoxic-ischemic brain damage in neonatal rats via improving antioxidant enzyme activities and inhibiting cell death. Neurochem Int. 2015;89:17-27 pubmed publisher |
| Hu L, Su C, Song X, Shi Q, Fu J, Xia X, et al. Tetrachlorobenzoquinone triggers the cleavage of Bid and promotes the cross-talk of extrinsic and intrinsic apoptotic signalings in pheochromocytoma (PC) 12 cells. Neurotoxicology. 2015;49:149-57 pubmed publisher |
| Shan X, Tian L, Zhang Y, Wang X, Yan Q, Liu J. Ginsenoside Rg3 suppresses FUT4 expression through inhibiting NF-κB/p65 signaling pathway to promote melanoma cell death. Int J Oncol. 2015;47:701-9 pubmed publisher |
| Lei Z, Wang J, Xiao H, Guo Y, Wang T, Li Q, et al. Lysine-specific demethylase 1 promotes the stemness and chemoresistance of Lgr5(+) liver cancer initiating cells by suppressing negative regulators of β-catenin signaling. Oncogene. 2015;34:3188-98 pubmed publisher |
| Yang T, Thakur A, Chen T, Yang L, Lei G, Liang Y, et al. MicroRNA-15a induces cell apoptosis and inhibits metastasis by targeting BCL2L2 in non-small cell lung cancer. Tumour Biol. 2015;36:4357-65 pubmed publisher |
| Zhang X, Han X, Yin L, Xu L, Qi Y, Xu Y, et al. Potent effects of dioscin against liver fibrosis. Sci Rep. 2015;5:9713 pubmed publisher |
| Zhao X, Shen L, Feng Y, Yu H, Wu X, Chang J, et al. Decreased expression of RPS15A suppresses proliferation of lung cancer cells. Tumour Biol. 2015;36:6733-40 pubmed publisher |
| Wang Y, Yan T, Ma L, Liu B. Effects of the total saponins from Dioscorea nipponica on immunoregulation in aplastic anemia mice. Am J Chin Med. 2015;43:289-303 pubmed publisher |
| Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, et al. DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway. Med Oncol. 2015;32:115 pubmed publisher |
| Shi J, Ren C, Liu H, Wang L, Zhu B, Huang W, et al. An ESRG-interacting protein, COXII, is involved in pro-apoptosis of human embryonic stem cells. Biochem Biophys Res Commun. 2015;460:130-5 pubmed publisher |
| Li X, Zou K, Gou J, Du Q, Li D, He X, et al. Effect of baicalin-copper on the induction of apoptosis in human hepatoblastoma cancer HepG2 cells. Med Oncol. 2015;32:72 pubmed publisher |
| Fu C, Xu D, Wang C, Jin Y, Liu Q, Meng Q, et al. Alpha-Lipoic Acid Promotes Osteoblastic Formation in H2O2 -Treated MC3T3-E1 Cells and Prevents Bone Loss in Ovariectomized Rats. J Cell Physiol. 2015;230:2184-201 pubmed publisher |
| Zhang X, Cao J, Zhang L, Li Y, Mi W. Deferoxamine attenuates lipopolysaccharide-induced neuroinflammation and memory impairment in mice. J Neuroinflammation. 2015;12:20 pubmed publisher |
| Yuan L, Zhou C, Lu Y, Hong M, Zhang Z, Zhang Z, et al. IFN-γ-mediated IRF1/miR-29b feedback loop suppresses colorectal cancer cell growth and metastasis by repressing IGF1. Cancer Lett. 2015;359:136-47 pubmed publisher |
| Li L, He L, Zhao J, Xiao J, Liu M, Li X, et al. MiR-17-5p up-regulates YES1 to modulate the cell cycle progression and apoptosis in ovarian cancer cell lines. J Cell Biochem. 2015;116:1050-9 pubmed publisher |
| Li X, Liu X, Xu Y, He Y, Liu J, Xie M. Expression profile of apoptotic and proliferative proteins in hypoxic HUVEC treated with statins. Int J Oncol. 2015;46:677-84 pubmed publisher |
| Xiao K, Zou W, Yang Z, Rehman Z, Ansari A, Yuan H, et al. The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats. Cell Tissue Res. 2015;359:605-618 pubmed publisher |
| Guo Z, Liu J, Zhang L, Su B, Xing Y, He Q, et al. KCNJ1 inhibits tumor proliferation and metastasis and is a prognostic factor in clear cell renal cell carcinoma. Tumour Biol. 2015;36:1251-9 pubmed publisher |
| Lu T, Yang W, Wang Z, Hu Z, Zeng X, Yang C, et al. Knockdown of glucose-regulated protein 78/binding immunoglobulin heavy chain protein expression by asymmetric small interfering RNA induces apoptosis in prostate cancer cells and attenuates migratory capability. Mol Med Rep. 2015;11:249-56 pubmed publisher |
| Yuan X, Du J, Hua S, Zhang H, Gu C, Wang J, et al. Suppression of autophagy augments the radiosensitizing effects of STAT3 inhibition on human glioma cells. Exp Cell Res. 2015;330:267-76 pubmed publisher |
| Zhang Y, Li R, Zhu J, Wang Z, Lv S, Xiong J. Etomidate increases mortality in septic rats through inhibition of nuclear factor kappa-B rather than by causing adrenal insufficiency. J Surg Res. 2015;193:399-406 pubmed publisher |
