MDM2 | Proteintech Group 19058-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

MDM2

catalog :

19058-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 35

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 3e	Wang Q, Jia S, Jiao Y, Xu L, Wang D, Chen X, et al. SSRP1 influences colorectal cancer cell growth and apoptosis via the AKT pathway. Int J Med Sci. 2019;16:1573-1582 pubmed publisher
western blot; human; 1:500	Zhang X, Pan Q, Pan K, Weng D, Wang Q, Zhao J, et al. Expression and prognostic role of ubiquitination factor E4B in primary hepatocellular carcinoma. Mol Carcinog. 2016;55:64-76 pubmed publisher
	Shan B, Zhao R, Zhou J, Zhang M, Qi X, Wang T, et al. AURKA Increase the Chemosensitivity of Colon Cancer Cells to Oxaliplatin by Inhibiting the TP53-Mediated DNA Damage Response Genes. Biomed Res Int. 2020;2020:8916729 pubmed publisher
	Pu X, Zhu L, Li F, Zheng J, Wu H, Fu Y, et al. Target molecular treatment markers in Intrahepatic Cholangiocarcinoma based on Chinese population. Pathol Res Pract. 2020;216:153116 pubmed publisher
	Tong D, Zhang J, Wang X, Li Q, Liu L, Yang J, et al. MeCP2 facilitates breast cancer growth via promoting ubiquitination-mediated P53 degradation by inhibiting RPL5/RPL11 transcription. Oncogenesis. 2020;9:56 pubmed publisher
	Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
	Wang J, Li G, Ming S, Wang C, Shi L, Su B, et al. BRD4 inhibition exerts anti-viral activity through DNA damage-dependent innate immune responses. PLoS Pathog. 2020;16:e1008429 pubmed publisher
	Zhang Y, Cui N, Zheng G. Ubiquitination of P53 by E3 ligase MKRN2 promotes melanoma cell proliferation. Oncol Lett. 2020;19:1975-1984 pubmed publisher
	Zhao Q, Zhu H, Xie X, Mao Q, Liu Y, He X, et al. Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways. Int J Mol Sci. 2020;21: pubmed publisher
	Dou Y, Huang D, Zeng X, Zhou Y, Jiang X, Yue C, et al. All-trans retinoic acid enhances the effect of Fra-1 to inhibit cell proliferation and metabolism in cervical cancer. Biotechnol Lett. 2020;42:1051-1060 pubmed publisher
	Liu H, Zhang W, Fang Y, Yang H, Tian L, Li K, et al. Neurotoxicity of aluminum oxide nanoparticles and their mechanistic role in dopaminergic neuron injury involving p53-related pathways. J Hazard Mater. 2020;392:122312 pubmed publisher
	Duan T, Jiao H, He G, Yan Y. Translation Efficiency and Degradation of ER-Associated mRNAs Modulated by ER-Anchored poly(A)-Specific Ribonuclease (PARN). Cells. 2020;9: pubmed publisher
	Liu J, Zhu Z, Liu Y, Wei L, Li B, Mao F, et al. MDM2 inhibition-mediated autophagy contributes to the pro-apoptotic effect of berberine in p53-null leukemic cells. Life Sci. 2020;242:117228 pubmed publisher
	Guo J, Fu W, Xiang M, Zhang Y, Zhou K, Xu C, et al. Notch1 Drives the Formation and Proliferation of Intrahepatic Cholangiocarcinoma. Curr Med Sci. 2019;39:929-937 pubmed publisher
	Li S, Han J, Guo G, Sun Y, Zhang T, Zhao M, et al. Voltage-gated sodium channels β3 subunit promotes tumorigenesis in hepatocellular carcinoma by facilitating p53 degradation. FEBS Lett. 2019;: pubmed publisher
	Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, et al. DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway. Oxid Med Cell Longev. 2019;2019:5414670 pubmed publisher
	Fan X, Wang Y, Song J, Wu H, Yang M, Lu L, et al. MDM2 inhibitor RG7388 potently inhibits tumors by activating p53 pathway in nasopharyngeal carcinoma. Cancer Biol Ther. 2019;:1-9 pubmed publisher
	Liang M, Li H, Wang Z, Cai L, Yang L. Rice protein reduces DNA damage by activating the p53 pathway and stimulating endogenous antioxidant response in growing and adult rats. J Sci Food Agric. 2019;: pubmed publisher
	Feng X, Yan N, Sun W, Zheng S, Jiang S, Wang J, et al. miR-4521-FAM129A axial regulation on ccRCC progression through TIMP-1/MMP2/MMP9 and MDM2/p53/Bcl2/Bax pathways. Cell Death Discov. 2019;5:89 pubmed publisher
	Qin F, Wang Y, Jiang X, Wang Y, Zhang N, Wen X, et al. Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma. J Enzyme Inhib Med Chem. 2019;34:909-926 pubmed publisher
	Fu R, Yang P, Sajid A, Li Z. Avenanthramide A Induces Cellular Senescence via miR-129-3p/Pirh2/p53 Signaling Pathway To Suppress Colon Cancer Growth. J Agric Food Chem. 2019;67:4808-4816 pubmed publisher
	Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. PPPDE1 promotes hepatocellular carcinoma development by negatively regulate p53 and apoptosis. Apoptosis. 2019;24:135-144 pubmed publisher
	Sun Y, Liu W, Wang C, Meng Q, Liu Z, Huo X, et al. Combination of dihydromyricetin and ondansetron strengthens antiproliferative efficiency of adriamycin in K562/ADR through downregulation of SORCIN: A new strategy of inhibiting P-glycoprotein. J Cell Physiol. 2019;234:3685-3696 pubmed publisher
	Liu L, Sun Y, Zhao Y, Wang Q, Guo H, Guo R, et al. Urea transport B gene induces melanoma B16 cell death via activation of p53 and mitochondrial apoptosis. Cancer Sci. 2018;109:3762-3773 pubmed publisher
	Luo Y, Mohsin A, Xu C, Wang Q, Hang H, Zhuang Y, et al. Co-culture with TM4 cells enhances the proliferation and migration of rat adipose-derived mesenchymal stem cells with high stemness. Cytotechnology. 2018;70:1409-1422 pubmed publisher
	Yang S, Liu L, Cao C, Song N, Wang Y, Ma S, et al. USP52 acts as a deubiquitinase and promotes histone chaperone ASF1A stabilization. Nat Commun. 2018;9:1285 pubmed publisher
	Su F, He W, Chen C, Liu M, Liu H, Xue F, et al. The long non-coding RNA FOXD2-AS1 promotes bladder cancer progression and recurrence through a positive feedback loop with Akt and E2F1. Cell Death Dis. 2018;9:233 pubmed publisher
	Xie X, Wang X, Liao W, Fei R, Wu N, Cong X, et al. MYL6B, a myosin light chain, promotes MDM2-mediated p53 degradation and drives HCC development. J Exp Clin Cancer Res. 2018;37:28 pubmed publisher
	Zhang W, Yao F, Zhang H, Li N, Zou X, Sui L, et al. The Potential Roles of the Apoptosis-Related Protein PDRG1 in Diapause Embryo Restarting of Artemia sinica. Int J Mol Sci. 2018;19: pubmed publisher
	Qiu W, Xia X, Qiu Z, Guo M, Yang Z. RasGRP3 controls cell proliferation and migration in papillary thyroid cancer by regulating the Akt-MDM2 pathway. Gene. 2017;633:35-41 pubmed publisher
	Wang L, Song G, Zhang X, Feng T, Pan J, Chen W, et al. PADI2-Mediated Citrullination Promotes Prostate Cancer Progression. Cancer Res. 2017;77:5755-5768 pubmed publisher
	Xue C, Wang C, Sun Y, Meng Q, Liu Z, Huo X, et al. Targeting P-glycoprotein function, p53 and energy metabolism: Combination of metformin and 2-deoxyglucose reverses the multidrug resistance of MCF-7/Dox cells to doxorubicin. Oncotarget. 2017;8:8622-8632 pubmed publisher
	Chang T, Wang S, Chen L, Shih Y, Chang L, Liu S, et al. Regulation of the Abundance of Kaposi's Sarcoma-Associated Herpesvirus ORF50 Protein by Oncoprotein MDM2. PLoS Pathog. 2016;12:e1005918 pubmed publisher
	Wang Y, Chen C, Pan Q, Wu Y, Zhao J, Jiang S, et al. Decreased TPD52 expression is associated with poor prognosis in primary hepatocellular carcinoma. Oncotarget. 2016;7:6323-34 pubmed publisher
	Jin Y, Cao B, Zhang M, Zhan Q, Herman J, Yu M, et al. RASSF10 suppresses hepatocellular carcinoma growth by activating P53 signaling and methylation of RASSF10 is a docetaxel resistant marker. Genes Cancer. 2015;6:231-40 pubmed

product information

CatalogNo :

19058-1-AP

AntigenName :

MDM2

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

Mdm2 p53 binding protein homolog (mouse)

Immunogen :

Peptide

Species :

artemia sinica, human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, COIP, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

Double minute 2 protein, hdm2, HDMX, MDM2, Oncoprotein Mdm2, p53 binding protein Mdm2

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

NM_002392

Category :

Apoptosis;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

WB 1:1000 ;