This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
GLI2-Specific
catalog :
18989-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, western blot knockout validation
citations: 21
Published Application/Species/Sample/DilutionReference
  • western blot knockout validation; human; loading ...; fig 4a
Adams C, Htwe H, Marsh T, Wang A, Montoya M, Subbaraj L, et al. Transcriptional control of subtype switching ensures adaptation and growth of pancreatic cancer. elife. 2019;8: pubmed publisher
  • western blot; human; loading ...; fig 4a
Tan Y, Hu Y, Xiao Q, Tang Y, Chen H, He J, et al. Silencing of brain-expressed X-linked 2 (BEX2) promotes colorectal cancer metastasis through the Hedgehog signaling pathway. Int J Biol Sci. 2020;16:228-238 pubmed publisher
  • western blot; human; loading ...; fig 4b
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, et al. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells. Oncol Lett. 2019;18:3081-3091 pubmed publisher
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, et al. Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway. Nutr Cancer. 2020;:1-11 pubmed publisher
Landova Sulcova M, Zahradnicek O, Dumková J, Dosedělová H, Krivanek J, Hampl M, et al. Developmental mechanisms driving complex tooth shape in reptiles. Dev Dyn. 2019;: pubmed publisher
Mao J, Tian Y, Wang C, Jiang K, Li R, Yao Y, et al. CBX2 Regulates Proliferation and Apoptosis via the Phosphorylation of YAP in Hepatocellular Carcinoma. J Cancer. 2019;10:2706-2719 pubmed publisher
Hayes C, Labuzan S, Menke J, Haddock A, Waddell D. Ttc39c is upregulated during skeletal muscle atrophy and modulates ERK1/2 MAP kinase and hedgehog signaling. J Cell Physiol. 2019;234:23807-23824 pubmed publisher
Wang X, Wang H, Zhang T, He M, Liang H, Wang H, et al. Inhibition of MicroRNA-195 Alleviates Neuropathic Pain by Targeting Patched1 and Inhibiting SHH Signaling Pathway Activation. Neurochem Res. 2019;44:1690-1702 pubmed publisher
Li X, Wu J, Liu S, Zhang K, Miao X, Li J, et al. miR-384-5p Targets Gli2 and Negatively Regulates Age-Related Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells. Stem Cells Dev. 2019;28:791-798 pubmed publisher
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed publisher
Song L, Chen X, Wang P, Gao S, Qu C, Liu L. Effects of baicalein on pancreatic cancer stem cells via modulation of sonic Hedgehog pathway. Acta Biochim Biophys Sin (Shanghai). 2018;50:586-596 pubmed publisher
Jin N, Zhu X, Cheng F, Zhang L. Disulfiram/copper targets stem cell-like ALDH+ population of multiple myeloma by inhibition of ALDH1A1 and Hedgehog pathway. J Cell Biochem. 2018;119:6882-6893 pubmed publisher
Qian W, Kong X, Zhang T, Wang D, Song J, Li Y, et al. Cigarette smoke stimulates the stemness of renal cancer stem cells via Sonic Hedgehog pathway. Oncogenesis. 2018;7:24 pubmed publisher
Matsumoto K, Shimo T, Kurio N, Okui T, Ibaragi S, Kunisada Y, et al. Low-intensity pulsed ultrasound stimulation promotes osteoblast differentiation through hedgehog signaling. J Cell Biochem. 2018;119:4352-4360 pubmed publisher
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, et al. Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway. Biochem Biophys Res Commun. 2017;493:521-527 pubmed publisher
Feuerstein M, Chleilat E, Khakipoor S, Michailidis K, Ophoven C, Roussa E. Expression patterns of key Sonic Hedgehog signaling pathway components in the developing and adult mouse midbrain and in the MN9D cell line. Cell Tissue Res. 2017;370:211-225 pubmed publisher
Zhu J, Yang X, Chen Y, Jiang Y, Wang S, Li Y, et al. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/?-catenin and Sonic Hedgehog Pathways. Phytother Res. 2017;31:680-688 pubmed publisher
Choi H, Shin J, Kim E, Park S, Bae I, Jo Y, et al. Primary Cilia Negatively Regulate Melanogenesis in Melanocytes and Pigmentation in a Human Skin Model. PLoS ONE. 2016;11:e0168025 pubmed publisher
Li J, Cai J, Zhao S, Yao K, Sun Y, Li Y, et al. GANT61, a GLI inhibitor, sensitizes glioma cells to the temozolomide treatment. J Exp Clin Cancer Res. 2016;35:184 pubmed
Zhou Q, Wu H, Wei Y, Zhu W. Effect of Smo SiRNA-mediated Hedgehog Signaling Pathway Inhibition on Palatal Fusion. Biomed Environ Sci. 2016;29:594-598 pubmed
Pang P, Shimo T, Takada H, Matsumoto K, Yoshioka N, Ibaragi S, et al. Expression pattern of sonic hedgehog signaling and calcitonin gene-related peptide in the socket healing process after tooth extraction. Biochem Biophys Res Commun. 2015;467:21-6 pubmed publisher
product information
CatalogNo :
18989-1-AP
AntigenName :
GLI2-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
GLI-Kruppel family member GLI2
Immunogen :
Peptide
Species :
chamaeleo calyptratus, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
mouse
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AW546128, GLI Kruppel family member GLI2, Gli2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_001081125
Category :
Membrane Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:200 ; IHC 1:200 ; WB 1:800 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.