This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
EGFR-Specific
catalog :
18986-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 42
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2a
Wang K, Zhu T, Zhao R. Filamin A regulates EGFR/ERK/Akt signaling and affects colorectal cancer cell growth and migration. Mol Med Rep. 2019;20:3671-3678 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 5c
Liu X, Chen H, Hou Y, Ma X, Ye M, Huang R, et al. Adaptive EGF expression sensitizes pancreatic cancer cells to ionizing radiation through activation of the cyclin D1/P53/PARP pathway. Int J Oncol. 2019;54:1466-1480 pubmed publisher
  • western blot; human; 1:1000; loading ...; fig 6
Liu Y, Wang C, Shan X, Wu J, Liu H, Liu H, et al. S100P is associated with proliferation and migration in nasopharyngeal carcinoma. Oncol Lett. 2017;14:525-532 pubmed publisher
  • western blot; mouse; 1:1000; loading ...; fig 4a
Shi J, Bei Y, Kong X, Liu X, Lei Z, Xu T, et al. miR-17-3p Contributes to Exercise-Induced Cardiac Growth and Protects against Myocardial Ischemia-Reperfusion Injury. Theranostics. 2017;7:664-676 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 6d
  • western blot; mouse; loading ...; fig 6c
Sakata K, Araki K, Nakano H, Nishina T, Komazawa Sakon S, Murai S, et al. Novel method to rescue a lethal phenotype through integration of target gene onto the X-chromosome. Sci Rep. 2016;6:37200 pubmed publisher
Yadav V, Huang Y, George T, Wei P, Sumitra M, Ho C, et al. Preclinical Evaluation of the Novel Small-Molecule MSI-N1014 for Treating Drug-Resistant Colon Cancer via the LGR5/β-catenin/miR-142-3p Network and Reducing Cancer-Associated Fibroblast Transformation. Cancers (Basel). 2020;12: pubmed publisher
Ryu W, Lee J, Park J, Cha P, Cho Y, Kim J, et al. Destabilization of β-catenin and RAS by targeting the Wnt/β-catenin pathway as a potential treatment for triple-negative breast cancer. Exp Mol Med. 2020;52:832-842 pubmed publisher
Li F, Zhao S, Cui Y, Guo T, Qiang J, Xie Q, et al. α1,6-Fucosyltransferase (FUT8) regulates the cancer-promoting capacity of cancer-associated fibroblasts (CAFs) by modifying EGFR core fucosylation (CF) in non-small cell lung cancer (NSCLC). Am J Cancer Res. 2020;10:816-837 pubmed
Liu A, Zuo Z, Liu L, Liu L. Down-regulation of NTSR3 inhibits cell growth and metastasis, as well as the PI3K-AKT and MAPK signaling pathways in colorectal cancer. Biochem Cell Biol. 2020;:1-8 pubmed publisher
Uemasu K, Tanabe N, Tanimura K, Hasegawa K, Mizutani T, Hamakawa Y, et al. Serine Protease Imbalance in the Small Airways and Development of Centrilobular Emphysema in Chronic Obstructive Pulmonary Disease. Am J Respir Cell Mol Biol. 2020;63:67-78 pubmed publisher
Yu X, Yang F, Jiang H, Fan L. RGFP966 Suppresses Tumor Growth and Migration Through Inhibition of EGFR Expression in Hepatocellular Carcinoma Cells in vitro. Drug Des Devel Ther. 2020;14:121-128 pubmed publisher
Yan D, Ye Y, Zhang J, Zhao J, Yu J, Luo Q. Human Neutrophil Elastase Induces MUC5AC Overexpression in Chronic Rhinosinusitis Through miR-146a. Am J Rhinol Allergy. 2020;34:59-69 pubmed publisher
Lv Y, Cang W, Li Q, Liao X, Zhan M, Deng H, et al. Erlotinib overcomes paclitaxel-resistant cancer stem cells by blocking the EGFR-CREB/GRβ-IL-6 axis in MUC1-positive cervical cancer. Oncogenesis. 2019;8:70 pubmed publisher
Chen S, Youhong T, Tan Y, He Y, Ban Y, Cai J, et al. EGFR-PKM2 signaling promotes the metastatic potential of nasopharyngeal carcinoma through induction of FOSL1 and ANTXR2. Carcinogenesis. 2019;: pubmed publisher
Liu R, Shuai Y, Luo J, Zhang Z. SEMA3C Promotes Cervical Cancer Growth and Is Associated With Poor Prognosis. Front Oncol. 2019;9:1035 pubmed publisher
Xu Q, Long Q, Zhu D, Fu D, Zhang B, Han L, et al. Targeting amphiregulin (AREG) derived from senescent stromal cells diminishes cancer resistance and averts programmed cell death 1 ligand (PD-L1)-mediated immunosuppression. Aging Cell. 2019;18:e13027 pubmed publisher
Liu K, Du S, Gao P, Zheng J. Verteporfin suppresses the proliferation, epithelial-mesenchymal transition and stemness of head and neck squamous carcinoma cells via inhibiting YAP1. J Cancer. 2019;10:4196-4207 pubmed publisher
Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, et al. DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway. Oxid Med Cell Longev. 2019;2019:5414670 pubmed publisher
Zhang M, Guo J, Hu X, Zhao S, Li S, Wang J. An in vivo anti-tumor effect of eckol from marine brown algae by improving the immune response. Food Funct. 2019;10:4361-4371 pubmed publisher
Huang Q, Li S, Zhang L, Qiao X, Zhang Y, Zhao X, et al. CAPE-pNO2 Inhibited the Growth and Metastasis of Triple-Negative Breast Cancer via the EGFR/STAT3/Akt/E-Cadherin Signaling Pathway. Front Oncol. 2019;9:461 pubmed publisher
Mao Y, Tu R, Huang Y, Mao D, Yang Z, Lau P, et al. The exocyst functions in niche cells to promote germline stem cell differentiation by directly controlling EGFR membrane trafficking. Development. 2019;: pubmed publisher
Chen Y, Liu Z, Wang H, Tang Z, Liu Y, Liang Z, et al. VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer. Int J Cancer. 2019;: pubmed publisher
Wang Q, Wang H, Shen J, Zhang R, Hong J, Li Z, et al. The anti-androgenic effects of cypermethrin mediated by non-classical testosterone pathway activation of mitogen-activated protein kinase cascade in mouse Sertoli cells. Ecotoxicol Environ Saf. 2019;177:58-65 pubmed publisher
Qin Z, Xiang C, Zhong F, Liu Y, Dong Q, Li K, et al. Transketolase (TKT) activity and nuclear localization promote hepatocellular carcinoma in a metabolic and a non-metabolic manner. J Exp Clin Cancer Res. 2019;38:154 pubmed publisher
Han L, Li L, Wang N, Xiong Y, Li Y, Gu Y. Relationship of Epidermal Growth Factor Receptor Expression with Clinical Symptoms and Metastasis of Invasive Breast Cancer. J Interferon Cytokine Res. 2018;: pubmed publisher
Wang T, Liu Y, Lv M, Xing Q, Zhang Z, He X, et al. miR-323-3p regulates the steroidogenesis and cell apoptosis in polycystic ovary syndrome (PCOS) by targeting IGF-1. Gene. 2018;683:87-100 pubmed publisher
Oku Y, Nishiya N, Sugiyama S, Sato H, Uehara Y. Sensitisation of Cancer Cells to MLN8237, an Aurora-A Inhibitor, by YAP/TAZ Inactivation. Anticancer Res. 2018;38:3471-3476 pubmed publisher
Lai X, Su W, Zhao H, Yang S, Zeng T, Wu W, et al. Loss of scinderin decreased expression of epidermal growth factor receptor and promoted apoptosis of castration-resistant prostate cancer cells. FEBS Open Bio. 2018;8:743-750 pubmed publisher
Wu D, Zhao B, Qi X, Peng F, Fu H, Chi X, et al. Nogo-B receptor promotes epithelial-mesenchymal transition in non-small cell lung cancer cells through the Ras/ERK/Snail1 pathway. Cancer Lett. 2018;418:135-146 pubmed publisher
Gao Y, Yu H, Liu Y, Liu X, Zheng J, Ma J, et al. Long Non-Coding RNA HOXA-AS2 Regulates Malignant Glioma Behaviors and Vasculogenic Mimicry Formation via the MiR-373/EGFR Axis. Cell Physiol Biochem. 2018;45:131-147 pubmed publisher
Huang C, Chen Y, Tsai H, Yeh Y, Su W, Ma C, et al. EGFR expression in patients with stage III colorectal cancer after adjuvant chemotherapy and on cancer cell function. Oncotarget. 2017;8:114663-114676 pubmed publisher
Zheng Q, Li Y, Zhang D, Cui X, Dai K, Yang Y, et al. ANP promotes proliferation and inhibits apoptosis of ovarian granulosa cells by NPRA/PGRMC1/EGFR complex and improves ovary functions of PCOS rats. Cell Death Dis. 2017;8:e3145 pubmed publisher
Chen Y, Zhang Y, Dong T, Xu Y, Zhang W, An T, et al. Hyperthermia with different temperatures inhibits proliferation and promotes apoptosis through the EGFR/STAT3 pathway in C6 rat glioma cells. Mol Med Rep. 2017;16:9401-9408 pubmed publisher
Liang J, Gao W, Cai L. Fucosyltransferase VII promotes proliferation via the EGFR/AKT/mTOR pathway in A549 cells. Onco Targets Ther. 2017;10:3971-3978 pubmed publisher
Elkaim R, Bugueno Valdebenito I, Benkirane Jessel N, Tenenbaum H. Porphyromonas gingivalis and its lipopolysaccharide differently modulate epidermal growth factor-dependent signaling in human gingival epithelial cells. J Oral Microbiol. 2017;9:1334503 pubmed publisher
Wei X, Li M, Ma M, Jia H, Zhang Y, Kang W, et al. Induction of apoptosis by FFJ-5, a novel naphthoquinone compound, occurs via downregulation of PKM2 in A549 and HepG2 cells. Oncol Lett. 2017;13:791-799 pubmed publisher
Li H, Lu Y, Pang Y, Li M, Cheng X, Chen J. Propofol enhances the cisplatin-induced apoptosis on cervical cancer cells via EGFR/JAK2/STAT3 pathway. Biomed Pharmacother. 2017;86:324-333 pubmed publisher
Zhang Z, Li H, Zhou C, Li Q, Ma L, Zhang Z, et al. Non-benzoquinone geldanamycin analogs trigger various forms of death in human breast cancer cells. J Exp Clin Cancer Res. 2016;35:149 pubmed
Geng S, Zheng Y, Meng M, Guo Z, Cao N, Ma X, et al. Gingerol Reverses the Cancer-Promoting Effect of Capsaicin by Increased TRPV1 Level in a Urethane-Induced Lung Carcinogenic Model. J Agric Food Chem. 2016;64:6203-11 pubmed publisher
Zhang Y, Zhang X, Huang J, Dong Q. Wnt signaling regulation of stem-like properties in human lung adenocarcinoma cell lines. Med Oncol. 2015;32:157 pubmed publisher
Huang W, Liu J, Feng X, Chen H, Zeng L, Huang G, et al. DLC-1 induces mitochondrial apoptosis and epithelial mesenchymal transition arrest in nasopharyngeal carcinoma by targeting EGFR/Akt/NF-κB pathway. Med Oncol. 2015;32:115 pubmed publisher
Lin B, Xiao C, Zhao W, Xiao L, Chen X, Li P, et al. Enoyl-coenzyme A hydratase short chain 1 silencing attenuates the proliferation of hepatocellular carcinoma by inhibiting epidermal growth factor signaling in vitro and in vivo. Mol Med Rep. 2015;12:1421-8 pubmed publisher
product information
CatalogNo :
18986-1-AP
AntigenName :
EGFR-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
epidermal growth factor receptor (erythroblastic leukemia viral (v-erb-b) oncogene homolog, avian)
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
EGFR, ERBB, ERBB1, HER1, mENA, PIG61, Proto oncogene c ErbB 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_005228
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Metabolism;Oncogene(s) and Tumor Suppressor(s);Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IP 1:500 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.