This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
iNOS
catalog :
18985-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunocytochemistry
citations: 126
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:1000; loading ...; fig 5a
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
Zhang N, Liu C, Jin L, Zhang R, Wang T, Wang Q, et al. Ketogenic Diet Elicits Antitumor Properties through Inducing Oxidative Stress, Inhibiting MMP-9 Expression, and Rebalancing M1/M2 Tumor-Associated Macrophage Phenotype in a Mouse Model of Colon Cancer. J Agric Food Chem. 2020;: pubmed publisher
Ma S, Wang Y, Zhou X, Li Z, Zhang Z, Wang Y, et al. MG53 Protects hUC-MSCs against Inflammatory Damage and Synergistically Enhances Their Efficacy in Neuroinflammation Injured Brain through Inhibiting NLRP3/Caspase-1/IL-1β Axis. ACS Chem Neurosci. 2020;11:2590-2601 pubmed publisher
Xu J, Duan Z, Qi X, Ou Y, Guo X, Zi L, et al. Injectable Gelatin Hydrogel Suppresses Inflammation and Enhances Functional Recovery in a Mouse Model of Intracerebral Hemorrhage. Front Bioeng Biotechnol. 2020;8:785 pubmed publisher
Yu Y, Cai W, Zhou J, Lu H, Wang Y, Song Y, et al. Anti-arthritis effect of berberine associated with regulating energy metabolism of macrophages through AMPK/ HIF-1α pathway. Int Immunopharmacol. 2020;87:106830 pubmed publisher
Teixeira J, Abdalla H, Basting R, Hammock B, Napimoga M, Clemente Napimoga J. Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats. Int Immunopharmacol. 2020;87:106841 pubmed publisher
Wu Y, Wang Z, Fu X, Lin Z, Yu K. Geraniol-mediated osteoarthritis improvement by down-regulating PI3K/Akt/NF-κB and MAPK signals: In vivo and in vitro studies. Int Immunopharmacol. 2020;86:106713 pubmed publisher
Wu Y, Wang Z, Lin Z, Fu X, Zhan J, Yu K. Salvianolic Acid A Has Anti-Osteoarthritis Effect In Vitro and In Vivo. Front Pharmacol. 2020;11:682 pubmed publisher
Zhao S, Xiao P, Cui H, Gong P, Lin C, Chen F, et al. Hypothermia-Induced Ubiquitination of Voltage-Dependent Anion Channel 3 Protects BV2 Microglia Cells From Cytotoxicity Following Oxygen-Glucose Deprivation/Recovery. Front Mol Neurosci. 2020;13:100 pubmed publisher
Zou G, Zhang X, Wang L, Li X, Xie T, Zhao J, et al. Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription. Theranostics. 2020;10:6839-6853 pubmed publisher
Yuan L, Li Q, Bai D, Shang X, Hu F, Chen Z, et al. La2O3 Nanoparticles Induce Reproductive Toxicity Mediated by the Nrf-2/ARE Signaling Pathway in Kunming Mice. Int J Nanomedicine. 2020;15:3415-3431 pubmed publisher
Han X, Ma W, Zhu Y, Sun X, Liu N. Advanced glycation end products enhance macrophage polarization to the M1 phenotype via the HIF-1α/PDK4 pathway. Mol Cell Endocrinol. 2020;514:110878 pubmed publisher
Kong H, Wang H, Zhuo Z, Li Z, Tian P, Wu J, et al. Inhibition of miR-181a-5p reduces astrocyte and microglia activation and oxidative stress by activating SIRT1 in immature rats with epilepsy. Lab Invest. 2020;100:1223-1237 pubmed publisher
Xu H, Qi Q, Yan X. Myricetin ameliorates sepsis-associated acute lung injury in a murine sepsis model. Naunyn Schmiedebergs Arch Pharmacol. 2020;: pubmed publisher
Zhang L, Lu X, Gong L, Cui L, Zhang H, Zhao W, et al. Tetramethylpyrazine Protects Blood-Spinal Cord Barrier Integrity by Modulating Microglia Polarization Through Activation of STAT3/SOCS3 and Inhibition of NF-кB Signaling Pathways in Experimental Autoimmune Encephalomyelitis Mice. Cell Mol Neurobiol. 2020;: pubmed publisher
Wang Y, Zhang H, Chen Q, Jiao F, Shi C, Pei M, et al. TNF-α/HMGB1 inflammation signalling pathway regulates pyroptosis during liver failure and acute kidney injury. Cell Prolif. 2020;53:e12829 pubmed publisher
Zhou J, Zhang X, Peng J, Xie Y, Du F, Guo K, et al. TSPO ligand Ro5-4864 modulates microglia/macrophages polarization after subarachnoid hemorrhage in mice. Neurosci Lett. 2020;729:134977 pubmed publisher
Yan Z, Lin Z, Wu Y, Zhan J, Qi W, Lin J, et al. The protective effect of myricitrin in osteoarthritis: An in vitro and in vivo study. Int Immunopharmacol. 2020;84:106511 pubmed publisher
Yang L, Cao H, Sun D, Hou B, Lin L, Shen Z, et al. Bone marrow mesenchymal stem cells combine with normothermic machine perfusion to improve rat donor liver quality-the important role of hepatic microcirculation in donation after circulatory death. Cell Tissue Res. 2020;381:239-254 pubmed publisher
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F. 10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells. Int Immunopharmacol. 2020;84:106501 pubmed publisher
Wang D, Zong C, Cheng K. Chicken thalamic injury induced by copper (II) or / and arsenite exposure involves oxidative stress and inflammation-induced apoptosis. Ecotoxicol Environ Saf. 2020;197:110554 pubmed publisher
Xie C, Ge M, Jin J, Xu H, Mao L, Geng S, et al. Mechanism investigation on Bisphenol S-induced oxidative stress and inflammation in murine RAW264.7 cells: The role of NLRP3 inflammasome, TLR4, Nrf2 and MAPK. J Hazard Mater. 2020;394:122549 pubmed publisher
Wu H, Wei M, Jiang X, Tan J, Xu W, Fan X, et al. lncRNA PVT1 Promotes Tumorigenesis of Colorectal Cancer by Stabilizing miR-16-5p and Interacting with the VEGFA/VEGFR1/AKT Axis. Mol Ther Nucleic Acids. 2020;20:438-450 pubmed publisher
Yang F, Li S, Cheng Y, Li J, Han X. Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells. Life Sci. 2020;252:117611 pubmed publisher
Zheng Y, Wang N, Wang S, Yang B, Situ H, Zhong L, et al. XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling. Cell Commun Signal. 2020;18:48 pubmed publisher
Yang W, Chen X, Wang S, Hu H, Cheng X, Xu L, et al. 4β-Hydroxywithanolide E from Goldenberry (Whole Fruits of Physalis peruviana L.) as a Promising Agent against Chronic Obstructive Pulmonary Disease. J Nat Prod. 2020;83:1217-1228 pubmed publisher
Lin Z, Fu C, Yan Z, Wu Y, Zhan J, Lou Z, et al. The protective effect of hesperetin in osteoarthritis: an in vitro and in vivo study. Food Funct. 2020;11:2654-2666 pubmed publisher
Zhao Y, Hao C, Bao L, Wang D, Li Y, Qu Y, et al. Silica particles disorganize the polarization of pulmonary macrophages in mice. Ecotoxicol Environ Saf. 2020;193:110364 pubmed publisher
Li S, Huang N, Dang X, Li L, Li Z, Zhang C, et al. A Comparison of Splenic Pathologic Change and Immune Function in HBV-Related Portal Hypertension and Chinese Budd-Chiari Syndrome Patients with Hypersplenism. Viral Immunol. 2020;33:112-121 pubmed publisher
Mo M, Li S, Dong Z, Li C, Sun Y, Li A, et al. S-allylmercaptocysteine ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting inflammation and oxidative stress via nuclear factor kappa B and Keap1/Nrf2 pathways. Int Immunopharmacol. 2020;81:106273 pubmed publisher
Wang D, Wang X, Si M, Yang J, Sun S, Wu H, et al. Exosome-encapsulated miRNAs contribute to CXCL12/CXCR4-induced liver metastasis of colorectal cancer by enhancing M2 polarization of macrophages. Cancer Lett. 2020;474:36-52 pubmed publisher
Huang H, Cai H, Zhang L, Hua Z, Shi J, Wei Y. Oroxylin A inhibits carcinogen-induced skin tumorigenesis through inhibition of inflammation by regulating SHCBP1 in mice. Int Immunopharmacol. 2020;80:106123 pubmed publisher
Lou L, Tian M, Chang J, Li F, Zhang G. MiRNA-192-5p attenuates airway remodeling and autophagy in asthma by targeting MMP-16 and ATG7. Biomed Pharmacother. 2020;122:109692 pubmed publisher
Wu B, Song Q, Zhang Y, Wang C, Yang M, Zhang J, et al. Antidepressant activity of ω-3 polyunsaturated fatty acids in ovariectomized rats: role of neuroinflammation and microglial polarization. Lipids Health Dis. 2020;19:4 pubmed publisher
Ji X, Yuan X, Ma L, Bi B, Zhu H, Lei Z, et al. Mesenchymal stem cell-loaded thermosensitive hydroxypropyl chitin hydrogel combined with a three-dimensional-printed poly(ε-caprolactone) /nano-hydroxyapatite scaffold to repair bone defects via osteogenesis, angiogenesis and immunomodulation. Theranostics. 2020;10:725-740 pubmed publisher
Zhang H, Gu H, Jia Q, Zhao Y, Li H, Shen S, et al. Syringin protects against colitis by ameliorating inflammation. Arch Biochem Biophys. 2020;680:108242 pubmed publisher
Zhang P, Yin Y, Wang T, Li W, Li C, Zeng X, et al. Maresin 1 mitigates concanavalin A-induced acute liver injury in mice by inhibiting ROS-mediated activation of NF-κB signaling. Free Radic Biol Med. 2020;147:23-36 pubmed publisher
Xie Y, Peng J, Pang J, Guo K, Zhang L, Yin S, et al. Biglycan regulates neuroinflammation by promoting M1 microglial activation in early brain injury after experimental subarachnoid hemorrhage. J Neurochem. 2020;152:368-380 pubmed publisher
Liu Z, Xie Y, Xiong Y, Liu S, Qiu C, Zhu Z, et al. TLR 7/8 agonist reverses oxaliplatin resistance in colorectal cancer via directing the myeloid-derived suppressor cells to tumoricidal M1-macrophages. Cancer Lett. 2020;469:173-185 pubmed publisher
Zhao Y, Lu F, Ye J, Ji M, Pang Y, Wang Y, et al. Myeloid-Derived Suppressor Cells and γδT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice. Front Immunol. 2019;10:3104 pubmed publisher
Xu C, Diao Y, Wang J, Xu H, Zhao M, Luan Z, et al. Intravenously infusing the secretome of adipose-derived mesenchymal stem cells ameliorates neuroinflammation and neurological functioning after traumatic brain injury. Stem Cells Dev. 2019;: pubmed publisher
Honjoh K, Nakajima H, Hirai T, Watanabe S, Matsumine A. Relationship of Inflammatory Cytokines From M1-Type Microglia/Macrophages at the Injured Site and Lumbar Enlargement With Neuropathic Pain After Spinal Cord Injury in the CCL21 Knockout (plt) Mouse. Front Cell Neurosci. 2019;13:525 pubmed publisher
Yang X, Li S, Zhao Y, Li S, Zhao T, Tai Y, et al. GRK2 Mediated Abnormal Transduction of PGE2-EP4-cAMP-CREB Signaling Induces the Imbalance of Macrophages Polarization in Collagen-Induced Arthritis Mice. Cells. 2019;8: pubmed publisher
Wang Z, Liang M, Li H, Cai L, Yang L. Rice Protein Exerts Anti-Inflammatory Effect in Growing and Adult Rats via Suppressing NF-κB Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Jiao F, Wang Y, Zhang W, Zhang H, Chen Q, Wang L, et al. AGK2 Alleviates Lipopolysaccharide Induced Neuroinflammation through Regulation of Mitogen-Activated Protein Kinase Phosphatase-1. J Neuroimmune Pharmacol. 2019;: pubmed publisher
Hong Y, Lee S, Choi J, Jin Y, Won J, Hong Y. Conditional Controlled Light/Dark Cycle Influences Exercise-Induced Benefits in a Rat Model with Osteoarthritis: In Vitro and In Vivo Study. J Clin Med. 2019;8: pubmed publisher
Wei H, Li C, Xin H, Li S, Bi Y, Li X, et al. Keel Fracture Causes Stress and Inflammatory Responses and Inhibits the Expression of the Orexin System in Laying Hens. Animals (Basel). 2019;9: pubmed publisher
You M, Miao Z, Pan Y, Hu F. Trans-10-hydroxy-2-decenoic acid alleviates LPS-induced blood-brain barrier dysfunction by activating the AMPK/PI3K/AKT pathway. Eur J Pharmacol. 2019;865:172736 pubmed publisher
Shu G, Qiu Y, Hao J, Fu Q, Deng X. γ-Oryzanol alleviates acetaminophen-induced liver injury: roles of modulating AMPK/GSK3β/Nrf2 and NF-κB signaling pathways. Food Funct. 2019;10:6858-6872 pubmed publisher
Hu Y, Gui Z, Zhou Y, Xia L, Lin K, Xu Y. Quercetin alleviates rat osteoarthritis by inhibiting inflammation and apoptosis of chondrocytes, modulating synovial macrophages polarization to M2 macrophages. Free Radic Biol Med. 2019;145:146-160 pubmed publisher
Zhang J, Dongwei Zhou -, Zhang Z, Xinhui Qu -, Kunwang Bao -, Guohui Lu -, et al. miR-let-7a suppresses α-Synuclein-induced microglia inflammation through targeting STAT3 in Parkinson's disease. Biochem Biophys Res Commun. 2019;519:740-746 pubmed publisher
Zong X, Dong Y, Li Y, Yang L, Li Y, Yang B, et al. Beneficial Effects of Theta-Burst Transcranial Magnetic Stimulation on Stroke Injury via Improving Neuronal Microenvironment and Mitochondrial Integrity. Transl Stroke Res. 2019;: pubmed publisher
Zhao J, Cao J, Yu L, Ma H. Dehydroepiandrosterone alleviates E. Coli O157:H7-induced inflammation by preventing the activation of p38 MAPK and NF-κB pathways in mice peritoneal macrophages. Mol Immunol. 2019;114:114-122 pubmed publisher
Li Q, Liu B, Breitkopf Heinlein K, Weng H, Jiang Q, Dong P, et al. Adenovirus‑mediated overexpression of bone morphogenetic protein‑9 promotes methionine choline deficiency‑induced non‑alcoholic steatohepatitis in non‑obese mice. Mol Med Rep. 2019;20:2743-2753 pubmed publisher
Song X, Shang P, Sun Z, Lu M, You G, Yan S, et al. Therapeutic effect of yttrium oxide nanoparticles for the treatment of fulminant hepatic failure. Nanomedicine (Lond). 2019;: pubmed publisher
Song G, Zhang Y, Yu S, Lv W, Guan Z, Sun M, et al. Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma. Phytother Res. 2019;: pubmed publisher
Wu Y, Lin Z, Yan Z, Wang Z, Fu X, Yu K. Sinomenine contributes to the inhibition of the inflammatory response and the improvement of osteoarthritis in mouse-cartilage cells by acting on the Nrf2/HO-1 and NF-κB signaling pathways. Int Immunopharmacol. 2019;75:105715 pubmed publisher
Wang Y, Ai L, Hai B, Cao Y, Li R, Li H, et al. Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis. Physiol Res. 2019;68:445-455 pubmed
Liu L, Liang L, Liang H, Wang M, Lu B, Xue M, et al. Fusobacterium nucleatum Aggravates the Progression of Colitis by Regulating M1 Macrophage Polarization via AKT2 Pathway. Front Immunol. 2019;10:1324 pubmed publisher
Zhang K, Zhang Y, Li N, Xing F, Zhao J, Yang T, et al. An herbal-compound-based combination therapy that relieves cirrhotic ascites by affecting the L-arginine/nitric oxide pathway: A metabolomics-based systematic study. J Ethnopharmacol. 2019;241:112034 pubmed publisher
Wang Y, He G, Tang H, Shi Y, Kang X, Lyu J, et al. Aspirin inhibits inflammation and scar formation in the injury tendon healing through regulating JNK/STAT-3 signalling pathway. Cell Prolif. 2019;52:e12650 pubmed publisher
Lin Z, Wu D, Huang L, Jiang C, Pan T, Kang X, et al. Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice. Front Pharmacol. 2019;10:570 pubmed publisher
Jin Y, Li Z, Chen H, Jiang X, Zhang Y, Wu F. Effect of dexmedetomidine on kidney injury in sepsis rats through TLR4/MyD88/NF-κB/iNOS signaling pathway. Eur Rev Med Pharmacol Sci. 2019;23:5020-5025 pubmed publisher
Nieto Veloza A, Wang Z, Zhong Q, Krishnan H, Dia V. BG-4 from Bitter Gourd (Momordica charantia) Differentially Affects Inflammation In Vitro and In Vivo. Antioxidants (Basel). 2019;8: pubmed publisher
Shi Q, Zhao L, Xu C, Zhang L, Zhao H. High Molecular Weight Hyaluronan Suppresses Macrophage M1 Polarization and Enhances IL-10 Production in PM2.5-Induced Lung Inflammation. Molecules. 2019;24: pubmed publisher
Liu B, Gu Y, Pei S, Peng Y, Chen J, Pham L, et al. Interleukin-1 receptor associated kinase (IRAK)-M -mediated type 2 microglia polarization ameliorates the severity of experimental autoimmune encephalomyelitis (EAE). J Autoimmun. 2019;: pubmed publisher
Yu H, Lin Y, Zeng R, Li X, Zhang T, Tasneem S, et al. Analgesic and anti-inflammatory effects and molecular mechanisms of Kadsura heteroclita stems, an anti-arthritic Chinese Tujia ethnomedicinal herb. J Ethnopharmacol. 2019;238:111902 pubmed publisher
Xu Y, Wei H, Wang J, Wang W, Gao J. Synthesis of andrographolide analogues and their neuroprotection and neurite outgrowth-promoting activities. Bioorg Med Chem. 2019;27:2209-2219 pubmed publisher
Zhang B, Wang G, He J, Yang Q, Li D, Li J, et al. Icariin attenuates neuroinflammation and exerts dopamine neuroprotection via an Nrf2-dependent manner. J Neuroinflammation. 2019;16:92 pubmed publisher
Yang Y, Pang B, Liu Z, Li J, Zhang Z, Zhang R, et al. 1-Trichloromethyl-1,2,3,4-tetrahydro-beta-carboline (TaClo) Induces the Apoptosis of Dopaminergic Neurons via Oxidative Stress and Neuroinflammation. Oxid Med Cell Longev. 2019;2019:1292891 pubmed publisher
Ren H, Yang H, Xie M, Wen Y, Liu Q, Li X, et al. Chondrocyte apoptosis in rat mandibular condyles induced by dental occlusion due to mitochondrial damage caused by nitric oxide. Arch Oral Biol. 2019;101:108-121 pubmed publisher
Zhang C, Li C, Jia X, Wang K, Tu Y, Wang R, et al. In Vitro and In Vivo Anti-Inflammatory Effects of Polyphyllin VII through Downregulating MAPK and NF-κB Pathways. Molecules. 2019;24: pubmed publisher
Zhao Y, Li Y, Qu R, Chen X, Wang W, Qiu C, et al. Cortistatin binds to TNF-α receptors and protects against osteoarthritis. EBioMedicine. 2019;41:556-570 pubmed publisher
Wang R, Dong Z, Lan X, Liao Z, Chen M. Sweroside Alleviated LPS-Induced Inflammation via SIRT1 Mediating NF-κB and FOXO1 Signaling Pathways in RAW264.7 Cells. Molecules. 2019;24: pubmed publisher
Zhou J, Yu Y, Yang X, Wang Y, Song Y, Wang Q, et al. Berberine attenuates arthritis in adjuvant-induced arthritic rats associated with regulating polarization of macrophages through AMPK/NF-кB pathway. Eur J Pharmacol. 2019;852:179-188 pubmed publisher
Monti D, Rigano M, Monti S, Peixoto H. Role of Antioxidants in the Protection from Aging-Related Diseases. Oxid Med Cell Longev. 2019;2019:7450693 pubmed publisher
Qu R, Chen X, Hu J, Fu Y, Peng J, Li Y, et al. Ghrelin protects against contact dermatitis and psoriasiform skin inflammation by antagonizing TNF-α/NF-κB signaling pathways. Sci Rep. 2019;9:1348 pubmed publisher
Guo Y, Guo X, Yan S, Zhang B, Shi B. Mechanism Underlying the Protective Effect of Selenium on NO-Induced Oxidative Damage in Bovine Mammary Epithelial Cells. Biol Trace Elem Res. 2019;: pubmed publisher
Du L, Shen K, Bai Y, Chao J, Hu G, Zhang Y, et al. Involvement of NLRP3 inflammasome in methamphetamine-induced microglial activation through miR-143/PUMA axis. Toxicol Lett. 2019;301:53-63 pubmed publisher
Daicheng H, Shiwen X, Huaping Z, Yong L, Qianqian Z, Changxia H. Fangchinoline Ameliorates the Expressions of Angiogenic Molecule in Cerebral Ischemia Induced Neuronal Degeneration in Neonatal Rats. Transl Neurosci. 2018;9:117-122 pubmed publisher
Ma Y, Ma B, Shang Y, Yin Q, Wang D, Xu S, et al. Flavonoid-Rich Ethanol Extract from the Leaves of Diospyros kaki Attenuates D-Galactose-Induced Oxidative Stress and Neuroinflammation-Mediated Brain Aging in Mice. Oxid Med Cell Longev. 2018;2018:8938207 pubmed publisher
Wang Y, Hai B, Ai L, Cao Y, Li R, Li H, et al. Tempol relieves lung injury in a rat model of chronic intermittent hypoxia via suppression of inflammation and oxidative stress. Iran J Basic Med Sci. 2018;21:1238-1244 pubmed publisher
Wei H, Zhang R, Su Y, Bi Y, Li X, Zhang X, et al. Effects of Acute Cold Stress After Long-Term Cold Stimulation on Antioxidant Status, Heat Shock Proteins, Inflammation and Immune Cytokines in Broiler Heart. Front Physiol. 2018;9:1589 pubmed publisher
Jiang Y, Liu J, Zhou Z, Liu K, Liu C. Diosmetin Attenuates Akt Signaling Pathway by Modulating Nuclear Factor Kappa-Light-Chain-Enhancer of Activated B Cells (NF-κB)/Inducible Nitric Oxide Synthase (iNOS) in Streptozotocin (STZ)-Induced Diabetic Nephropathy Mice. Med Sci Monit. 2018;24:7007-7014 pubmed publisher
Wu M, Xu L, Wang Y, Zhou N, Zhen F, Zhang Y, et al. S100A8/A9 induces microglia activation and promotes the apoptosis of oligodendrocyte precursor cells by activating the NF-κB signaling pathway. Brain Res Bull. 2018;143:234-245 pubmed publisher
Liao D, Xiang D, Dang R, Xu P, Wang J, Han W, et al. Neuroprotective Effects of dl-3-n-Butylphthalide against Doxorubicin-Induced Neuroinflammation, Oxidative Stress, Endoplasmic Reticulum Stress, and Behavioral Changes. Oxid Med Cell Longev. 2018;2018:9125601 pubmed publisher
Yang W, Li Y, Gao H, Wu X, Wang X, Wang X, et al. Protective effect of the ethanol extract from Ligusticum chuanxiong rhizome against streptozotocin-induced diabetic nephropathy in mice. J Ethnopharmacol. 2018;227:166-175 pubmed publisher
Cheng L, Chen L, Wei X, Wang Y, Ren Z, Zeng S, et al. NOD2 promotes dopaminergic degeneration regulated by NADPH oxidase 2 in 6-hydroxydopamine model of Parkinson's disease. J Neuroinflammation. 2018;15:243 pubmed publisher
Liu X, Jiang M, Ren L, Zhang A, Zhao M, Zhang H, et al. Decidual macrophage M1 polarization contributes to adverse pregnancy induced by Toxoplasma gondii PRU strain infection. Microb Pathog. 2018;124:183-190 pubmed publisher
Huang Y, He J, Liang H, Hu K, Jiang S, Yang L, et al. Aryl Hydrocarbon Receptor Regulates Apoptosis and Inflammation in a Murine Model of Experimental Autoimmune Uveitis. Front Immunol. 2018;9:1713 pubmed publisher
Leng B, Tang F, Lü M, Zhang Z, Wang H, Zhang Y. Astragaloside IV improves vascular endothelial dysfunction by inhibiting the TLR4/NF-?B signaling pathway. Life Sci. 2018;209:111-121 pubmed publisher
Liu L, Jin M, Tao Q, Yu L, Du J, Wang C, et al. Effective Amelioration of Liver Fibrosis Through Lentiviral Vector Carrying Toxoplasma gondii gra15II in Murine Model. Front Immunol. 2018;9:1572 pubmed publisher
Xu B, Lian S, Li S, Guo J, Wang J, Wang D, et al. GABAB receptor mediate hippocampal neuroinflammation in adolescent male and female mice after cold expose. Brain Res Bull. 2018;142:163-175 pubmed publisher
Huang S, Qiu G, Cheng F, Pei Z, Yang Z, Deng X, et al. Berberine Protects Secondary Injury in Mice with Traumatic Brain Injury Through Anti-oxidative and Anti-inflammatory Modulation. Neurochem Res. 2018;43:1814-1825 pubmed publisher
He J, Lu X, Wei T, Dong Y, Cai Z, Tang L, et al. Asperuloside and Asperulosidic Acid Exert an Anti-Inflammatory Effect via Suppression of the NF-κB and MAPK Signaling Pathways in LPS-Induced RAW 264.7 Macrophages. Int J Mol Sci. 2018;19: pubmed publisher
Lu H, Wu L, Liu L, Ruan Q, Zhang X, Hong W, et al. Quercetin ameliorates kidney injury and fibrosis by modulating M1/M2 macrophage polarization. Biochem Pharmacol. 2018;154:203-212 pubmed publisher
Li Y, Li G, Sun L, Li L, Liu Y, Kong D, et al. Ingredients from Litsea garrettii as Potential Preventive Agents against Oxidative Insult and Inflammatory Response. Oxid Med Cell Longev. 2018;2018:7616852 pubmed publisher
Li Y, Fu C, Yang W, Wang X, Feng D, Wang X, et al. Investigation of constituents from Cinnamomum camphora (L.) J. Presl and evaluation of their anti-inflammatory properties in lipopolysaccharide-stimulated RAW 264.7 macrophages. J Ethnopharmacol. 2018;221:37-47 pubmed publisher
Zeng J, Zhao H, Liu Z, Zhang W, Huang Y. Lipopolysaccharide Induces Subacute Cerebral Microhemorrhages with Involvement of Nitric Oxide Synthase in Rats. J Stroke Cerebrovasc Dis. 2018;27:1905-1913 pubmed publisher
Liang M, Wang Z, Li H, Cai L, Pan J, He H, et al. l-Arginine induces antioxidant response to prevent oxidative stress via stimulation of glutathione synthesis and activation of Nrf2 pathway. Food Chem Toxicol. 2018;115:315-328 pubmed publisher
Yang X, Wang J, Zhou Z, Jiang R, Huang J, Chen L, et al. Silica-induced initiation of circular ZC3H4 RNA/ZC3H4 pathway promotes the pulmonary macrophage activation. FASEB J. 2018;32:3264-3277 pubmed publisher
Teng Y, Feng C, Liu Y, Jin H, Gao Y, Li T. Anti-inflammatory effect of tranexamic acid against trauma-hemorrhagic shock-induced acute lung injury in rats. Exp Anim. 2018;67:313-320 pubmed publisher
Yang L, Tucker D, Dong Y, Wu C, Lu Y, Li Y, et al. Photobiomodulation therapy promotes neurogenesis by improving post-stroke local microenvironment and stimulating neuroprogenitor cells. Exp Neurol. 2018;299:86-96 pubmed publisher
Zheng X, Ma W, Sun R, Yin H, Lin F, Liu Y, et al. Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity. Redox Biol. 2018;14:237-249 pubmed publisher
Dang R, Zhou X, Tang M, Xu P, Gong X, Liu Y, et al. Fish oil supplementation attenuates neuroinflammation and alleviates depressive-like behavior in rats submitted to repeated lipopolysaccharide. Eur J Nutr. 2018;57:893-906 pubmed publisher
Xie Y, Wen H, Yan K, Wang S, Wang X, Chen J, et al. Toxoplasma gondii GRA15II effector-induced M1 cells ameliorate liver fibrosis in mice infected with Schistosomiasis japonica. Cell Mol Immunol. 2018;15:120-134 pubmed publisher
Wang X, Li D, Fan L, Xiao Q, Zuo H, Li Z. CAPE-pNO2 ameliorated diabetic nephropathy through regulating the Akt/NF-?B/ iNOS pathway in STZ-induced diabetic mice. Oncotarget. 2017;8:114506-114525 pubmed publisher
Huang X, Peng J, Pang J, Tian X, Li X, Wu Y, et al. Peli1 Contributions in Microglial Activation, Neuroinflammatory Responses and Neurological Deficits Following Experimental Subarachnoid Hemorrhage. Front Mol Neurosci. 2017;10:398 pubmed publisher
Zuo T, Zhu M, Xu W, Wang Z, Song H. Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome. Cell Physiol Biochem. 2017;43:1855-1865 pubmed publisher
Yan Y, Du Y, Zheng H, Wang G, Li R, Chen J, et al. NS1 of H7N9 Influenza A Virus Induces NO-Mediated Cellular Senescence in Neuro2a Cells. Cell Physiol Biochem. 2017;43:1369-1380 pubmed publisher
Li S, Zhao H, Wang Y, Shao Y, Li J, Liu J, et al. The inflammatory responses in Cu-mediated elemental imbalance is associated with mitochondrial fission and intrinsic apoptosis in Gallus gallus heart. Chemosphere. 2017;189:489-497 pubmed publisher
Guo Y, Sun J, Li T, Zhang Q, Bu S, Wang Q, et al. Melatonin ameliorates restraint stress-induced oxidative stress and apoptosis in testicular cells via NF-κB/iNOS and Nrf2/ HO-1 signaling pathway. Sci Rep. 2017;7:9599 pubmed publisher
Chen G, Deng H, Song X, Lu M, Zhao L, Xia S, et al. Reactive oxygen species-responsive polymeric nanoparticles for alleviating sepsis-induced acute liver injury in mice. Biomaterials. 2017;144:30-41 pubmed publisher
Maryam A, Mehmood T, Zhang H, Li Y, Khan M, Ma T. Alantolactone induces apoptosis, promotes STAT3 glutathionylation and enhances chemosensitivity of A549 lung adenocarcinoma cells to doxorubicin via oxidative stress. Sci Rep. 2017;7:6242 pubmed publisher
Ahmed Abdel Reheim M, Messiha B, Abo Saif A. Quillaja saponaria bark saponin protects Wistar rats against ferrous sulphate-induced oxidative and inflammatory liver damage. Pharm Biol. 2017;55:1972-1983 pubmed publisher
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product information
CatalogNo :
18985-1-AP
AntigenName :
iNOS
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
nitric oxide synthase 2, inducible
Immunogen :
Peptide
Species :
chicken, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
HEP NOS, Hepatocyte NOS, Inducible NO synthase, Inducible NOS, INOS, NOS, NOS type II, NOS2, NOS2A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000625
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.