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product summary
company name :
Proteintech Group
product type :
antibody
product name :
TGF-beta 1
catalog :
18978-1-AP
quantity :
150
price :
279 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, dog
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section
citations: 38
Published Application/Species/DilutionReference
  • immunohistochemistry - paraffin section; human; 1:100; fig 1
Ruan H, Wang T, Yang C, Jin G, Gu D, Deng X, et al. Co-expression of LASS2 and TGF-β1 predicts poor prognosis in hepatocellular carcinoma. Sci Rep. 2016;6:32421 pubmed publisher
  • western blot; mouse; 1:500; fig 6f
Wang Y, Duan W, Wang W, Di Wen -, Liu Y, Liu Y, et al. scAAV9-VEGF prolongs the survival of transgenic ALS mice by promoting activation of M2 microglia and the PI3K/Akt pathway. Brain Res. 2016;1648:1-10 pubmed publisher
Ma S, Mao L, Deng W, Li Y, Bu L, Yu G, et al. AGR2 promotes the proliferation, migration and regulates epithelial-mesenchymal transition in salivary adenoid cystic carcinoma.. Am J Transl Res. 2017;9:507-519 pubmed
Boutin A, Liao W, Wang M, Hwang S, Karpinets T, Cheung H, et al. Oncogenic Kras drives invasion and maintains metastases in colorectal cancer.. Genes Dev. 2017;31:370-382 pubmed publisher
Liu Y, Wang T, Liu X, Wei X, Xu T, Yin M, et al. Neuronal zinc-α2-glycoprotein is decreased in temporal lobe epilepsy in patients and rats.. Neuroscience. 2017;357:56-66 pubmed publisher
Lu Y, Dong Y, Tucker D, Wang R, Ahmed M, Brann D, et al. Treadmill Exercise Exerts Neuroprotection and Regulates Microglial Polarization and Oxidative Stress in a Streptozotocin-Induced Rat Model of Sporadic Alzheimer's Disease.. J Alzheimers Dis. 2017;56:1469-1484 pubmed publisher
Ning B, Zhang Y, Wu D, Cui J, Liu L, Wang P, et al. Luteolin-7-diglucuronide attenuates isoproterenol-induced myocardial injury and fibrosis in mice. Acta Pharmacol Sin. 2017;: pubmed publisher
Sa G, Xiong X, Ren J, Zhao Y, He S. Expression of fibrosis-related molecules in the oral mucosa of six animal species: A reference for selecting animal models. Eur J Pharm Sci. 2017;96:472-478 pubmed publisher
Chen N, Hao J, Li L, Li F, Liu S, Duan H. Carboxy-terminal modulator protein attenuated extracellular matrix deposit by inhibiting phospho-Akt, TGF-β1 and α-SMA in kidneys of diabetic mice. Biochem Biophys Res Commun. 2016;474:753-60 pubmed publisher
Wu J, Lu M, Li Y, Shang Y, Wang S, Meng Y, et al. Regulation of a TGF-β1-CD147 self-sustaining network in the differentiation plasticity of hepatocellular carcinoma cells. Oncogene. 2016;35:5468-5479 pubmed publisher
Li L, Yang L, Wang L, Wang F, Zhang Z, Li J, et al. Impaired T cell function in malignant pleural effusion is caused by TGF-β derived predominantly from macrophages. Int J Cancer. 2016;139:2261-9 pubmed publisher
Yan N, Wen L, Peng R, Li H, Liu H, Peng H, et al. Naringenin Ameliorated Kidney Injury through Let-7a/TGFBR1 Signaling in Diabetic Nephropathy. J Diabetes Res. 2016;2016:8738760 pubmed publisher
Zhang G, Yang G, Deng Y, Zhao X, Yang Y, Rao J, et al. Ameliorative effects of Xue-Fu-Zhu-Yu decoction, Tian-Ma-Gou-Teng-Yin and Wen-Dan decoction on myocardial fibrosis in a hypertensive rat mode. BMC Complement Altern Med. 2016;16:56 pubmed publisher
Zhu D, Zhang L, Cheng L, Ren L, Tang J, Sun D. Pancreatic Kininogenase Ameliorates Renal Fibrosis in Streptozotocin Induced-Diabetic Nephropathy Rat. Kidney Blood Press Res. 2016;41:9-17 pubmed publisher
Zhang J, An S, Fu J, Liu P, Shao T, Li M, et al. Mixed Aqueous Extract of Salvia Miltiorrhiza Reduces Blood Pressure through Inhibition of Vascular Remodelling and Oxidative Stress in Spontaneously Hypertensive Rats. Cell Physiol Biochem. 2016;40:347-360 pubmed
Liu J, Wu J, Sun A, Sun Y, Yu X, Liu N, et al. Hydrogen sulfide decreases high glucose/palmitate-induced autophagy in endothelial cells by the Nrf2-ROS-AMPK signaling pathway. Cell Biosci. 2016;6:33 pubmed publisher
Duan H, Ma L, Liu H, Zhang Y, Zhang Z, Yan X, et al. Tanshinone IIA attenuates epithelial-mesenchymal transition to inhibit the tracheal narrowing. J Surg Res. 2016;206:252-262 pubmed publisher
Hou Y, Li S, Wu M, Wei J, Ren Y, Du C, et al. Mitochondria-targeted peptide SS-31 attenuates renal injury via an antioxidant effect in diabetic nephropathy. Am J Physiol Renal Physiol. 2016;310:F547-59 pubmed publisher
Cao X, Liu X, Li M, Zhang Y, Chen L, Wang L, et al. Overexpression of Prolyl-4-Hydroxylase-α1 Stabilizes but Increases Shear Stress-Induced Atherosclerotic Plaque in Apolipoprotein E-Deficient Mice. Dis Markers. 2016;2016:1701637 pubmed
Zhang Y, Wang J, Zhang Y, Wang Y, Wang J, Zhao Y, et al. Deletion of interleukin-6 alleviated interstitial fibrosis in streptozotocin-induced diabetic cardiomyopathy of mice through affecting TGFβ1 and miR-29 pathways. Sci Rep. 2016;6:23010 pubmed publisher
Mao X, Luo W, Sun J, Yang N, Zhang L, Zhao Z, et al. Usp2-69 overexpression slows down the progression of rat anti-Thy1.1 nephritis. Exp Mol Pathol. 2016;101:249-258 pubmed publisher
Zhang Z, Zhang D, Dou M, Li Z, Zhang J, Zhao X. Dendrobium officinale Kimura et Migo attenuates diabetic cardiomyopathy through inhibiting oxidative stress, inflammation and fibrosis in streptozotocin-induced mice. Biomed Pharmacother. 2016;84:1350-1358 pubmed publisher
Song Y, Yu Y, Wang D, Chai S, Liu D, Xiao X, et al. Maternal high-fat diet feeding during pregnancy and lactation augments lung inflammation and remodeling in the offspring. Respir Physiol Neurobiol. 2015;207:1-6 pubmed publisher
Xu R, Bi C, Song J, Wang L, Ge C, Liu X, et al. Upregulation of miR-142-5p in atherosclerotic plaques and regulation of oxidized low-density lipoprotein-induced apoptosis in macrophages. Mol Med Rep. 2015;11:3229-34 pubmed publisher
Liu G, Shi Y, Peng X, Liu H, Peng Y, He L. Astaxanthin attenuates adriamycin-induced focal segmental glomerulosclerosis. Pharmacology. 2015;95:193-200 pubmed publisher
Chen M, Zhang J, Wang J, Gao L, Chen X, Xiao J. Anti-fibrotic effects of neferine on carbon tetrachloride-induced hepatic fibrosis in mice. Am J Chin Med. 2015;43:231-40 pubmed publisher
Li Q, Liu G, Shao D, Wang J, Yuan H, Chen T, et al. Mucin1 mediates autocrine transforming growth factor beta signaling through activating the c-Jun N-terminal kinase/activator protein 1 pathway in human hepatocellular carcinoma cells. Int J Biochem Cell Biol. 2015;59:116-25 pubmed publisher
Azzimonti B, Zavattaro E, Provasi M, Vidali M, Conca A, Catalano E, et al. Intense Foxp3+ CD25+ regulatory T-cell infiltration is associated with high-grade cutaneous squamous cell carcinoma and counterbalanced by CD8+/Foxp3+ CD25+ ratio. Br J Dermatol. 2015;172:64-73 pubmed publisher
Du C, Shi Y, Ren Y, Wu H, Yao F, Wei J, et al. Anthocyanins inhibit high-glucose-induced cholesterol accumulation and inflammation by activating LXRα pathway in HK-2 cells. Drug Des Devel Ther. 2015;9:5099-113 pubmed publisher
Zhong W, Chen G, Zhang W, Ren J, Wu Z, Zhao Y, et al. Epithelial-mesenchymal transition in keratocystic odontogenic tumor: possible role in locally aggressive behavior. Biomed Res Int. 2015;2015:168089 pubmed publisher
Jia M, Hu J, Li W, Su P, Zhang H, Zhang X, et al. Trps1 is associated with the multidrug resistance of osteosarcoma by regulating MDR1 gene expression. FEBS Lett. 2014;588:801-10 pubmed publisher
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, et al. Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model. J Nat Med. 2013;67:86-97 pubmed publisher
Li W, Cui M, Wei Y, Kong X, Tang L, Xu D. Inhibition of the expression of TGF-β1 and CTGF in human mesangial cells by exendin-4, a glucagon-like peptide-1 receptor agonist. Cell Physiol Biochem. 2012;30:749-57 pubmed publisher
Ding Z, Jin G, Liang H, Wang W, Chen W, Datta P, et al. Transforming growth factor β induces expression of connective tissue growth factor in hepatic progenitor cells through Smad independent signaling. Cell Signal. 2013;25:1981-92 pubmed publisher
Zhang Q, Xiao X, Li M, Li W, Yu M, Zhang H, et al. Gene expression profiling in glomeruli of diabetic nephropathy rat. Exp Biol Med (Maywood). 2012;237:903-11 pubmed publisher
Wei J, Shi Y, Hou Y, Ren Y, Du C, Zhang L, et al. Knockdown of thioredoxin-interacting protein ameliorates high glucose-induced epithelial to mesenchymal transition in renal tubular epithelial cells. Cell Signal. 2013;25:2788-96 pubmed publisher
Qu Y, RAY P, Li J, Cai Q, Bagaria S, Moran C, et al. High levels of secreted frizzled-related protein 1 correlate with poor prognosis and promote tumourigenesis in gastric cancer. Eur J Cancer. 2013;49:3718-28 pubmed publisher
Li G, Li Y, Liu S, Shi Y, Chi Y, Liu G, et al. Gremlin aggravates hyperglycemia-induced podocyte injury by a TGFβ/smad dependent signaling pathway. J Cell Biochem. 2013;114:2101-13 pubmed publisher
product information
Catalog Number :
18978-1-AP
Item Name :
TGF-beta 1
Quantity / Package Size :
150
FullName :
transforming growth factor, beta 1
Antigen :
Peptide
Species Reactivity :
human, human; dog; miniping;rat; sheep; buffloa; pig, mouse, rat
Host Species :
Rabbit
Conjugate :
Unconjugated
Antigen Species :
human
Applications :
ELISA, IF, IHC, WB
Type :
Polyclonal
Isotype :
IgG
Antigen Synonyms :
CED, DPD1, LAP, TGF beta 1, TGFB, TGFB1, TGFbeta, TGF-beta1, TGF-β1
Primary or Secondary? :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000660
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Growth Factor/Cytokine/Hormone;Membrane Proteins;Neurology;Signal transduction;
Price :
279 USD
Form/Purification :
Antigen affinity purification
PMID :
22434410, 22890152, 23553804, 23727026, 23927957, 24041652, 24491996, 24910265, 25500158, 25526895, 25586666, 25800905, 25879017, 25924598, 26379423, 26719366, 26751697, 26852136, 26972749, 27041581, 27166156, 27222705, 27392886, 27446963, 27459735, 27581744, 27640956, 27769912, 27802903, 27818566, 27866193, 27916370, 28112175, 28157094, 28289141, 28337279, 28576733
IsSellable :
1
AppTiter :
WB 1:600 ; IHC 1:200 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.