This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
LC3B-Specific
catalog :
18725-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 104
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 2g
Gao H, Zhang J, Ren X. PD-L1 regulates tumorigenesis and autophagy of ovarian cancer by activating mTORC signaling. Biosci Rep. 2019;39: pubmed publisher
Liu W, Zhou J, Niu F, Pu F, Wang Z, Huang M, et al. Mycobacterium tuberculosis infection increases the number of osteoclasts and inhibits osteoclast apoptosis by regulating TNF-α-mediated osteoclast autophagy. Exp Ther Med. 2020;20:1889-1898 pubmed publisher
Xu X, Chen B, Huang Q, Wu Y, Liang T. The Effects of Puerarin on Autophagy Through Regulating of the PERK/eIF2α/ATF4 Signaling Pathway Influences Renal Function in Diabetic Nephropathy. Diabetes Metab Syndr Obes. 2020;13:2583-2592 pubmed publisher
Zhou J, Wang Z, He Y, Luo X, Zhang W, Yu L, et al. Qiliqiangxin reduced cardiomyocytes apotosis and improved heart function in infarcted heart through Pink1/Parkin -mediated mitochondrial autophagy. BMC Complement Med Ther. 2020;20:203 pubmed publisher
Zhou F, Xiong X, Li S, Liang J, Zhang X, Tian M, et al. Enhanced autophagic retrograde axonal transport by dynein intermediate chain upregulation improves Aβ clearance and cognitive function in APP/PS1 double transgenic mice. Aging (Albany NY). 2020;12:12142-12159 pubmed publisher
Wang M, Zhang M, Feng Y, Xing Y, Tan Z, Li W, et al. Electroacupuncture Inhibits Neuronal Autophagy and Apoptosis via the PI3K/AKT Pathway Following Ischemic Stroke. Front Cell Neurosci. 2020;14:134 pubmed publisher
Luo Y, Peng J, Huang C, Cao Y. Graphene oxide size-dependently altered lipid profiles in THP-1 macrophages. Ecotoxicol Environ Saf. 2020;199:110714 pubmed publisher
Ruan C, Wang C, Gong X, Zhang Y, Deng W, Zhou J, et al. An integrative multi-omics approach uncovers the regulatory role of CDK7 and CDK4 in autophagy activation induced by silica nanoparticles. Autophagy. 2020;:1-22 pubmed publisher
Guo W, Liu J, Li W, Ma H, Gong Q, Kan X, et al. Niacin Alleviates Dairy Cow Mastitis by Regulating the GPR109A/AMPK/NRF2 Signaling Pathway. Int J Mol Sci. 2020;21: pubmed publisher
Wang J, Zhu H, Wang K, Yang Z, Liu Z. Protective effect of quercetin on rat testes against cadmium toxicity by alleviating oxidative stress and autophagy. Environ Sci Pollut Res Int. 2020;27:25278-25286 pubmed publisher
Wang L, Tan Z, Zhang Y, Kady Keita N, Liu H, Zhang Y. ADAM12 silencing promotes cellular apoptosis by activating autophagy in choriocarcinoma cells. Int J Oncol. 2020;56:1162-1174 pubmed publisher
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F. 10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells. Int Immunopharmacol. 2020;84:106501 pubmed publisher
Sun Y, Lu F, Yu X, Wang B, Chen J, Lu F, et al. Exogenous H2S Promoted USP8 Sulfhydration to Regulate Mitophagy in the Hearts of db/db Mice. Aging Dis. 2020;11:269-285 pubmed publisher
Li K, Deng Y, Deng G, Chen P, Wang Y, Wu H, et al. High cholesterol induces apoptosis and autophagy through the ROS-activated AKT/FOXO1 pathway in tendon-derived stem cells. Stem Cell Res Ther. 2020;11:131 pubmed publisher
Ma R, Zhang B, Zhang Z, Deng Q. LncRNA MALAT1 knockdown inhibits cell migration and invasion by suppressing autophagy through miR-384/GOLM1 axis in glioma. Eur Rev Med Pharmacol Sci. 2020;24:2601-2615 pubmed publisher
Jiang W, Ma P, Deng L, Liu Z, Wang X, Liu X, et al. Hepatitis A virus structural protein pX interacts with ALIX and promotes the secretion of virions and foreign proteins through exosome-like vesicles. J Extracell Vesicles. 2020;9:1716513 pubmed publisher
Zheng Y, Zhu G, Tang Y, Yan J, Han S, Yin J, et al. HDAC6, A Novel Cargo for Autophagic Clearance of Stress Granules, Mediates the Repression of the Type I Interferon Response During Coxsackievirus A16 Infection. Front Microbiol. 2020;11:78 pubmed publisher
Tan X, Zhang K, Xu J, Qu D, Chen L, Li J, et al. Luteolin alleviates methamphetamine-induced neurotoxicity by suppressing PI3K/Akt pathway-modulated apoptosis and autophagy in rats. Food Chem Toxicol. 2020;137:111179 pubmed publisher
Zheng Y, Zhu G, Yan J, Tang Y, Han S, Yin J, et al. The Late Domain of Prototype Foamy Virus Gag Facilitates Autophagic Clearance of Stress Granules by Promoting Amphisome Formation. J Virol. 2020;94: pubmed publisher
Zhou Y, Fu X, Guan Y, Gong M, He K, Huang B. 1,3-Dicaffeoylquinic acid targeting 14-3-3 tau suppresses human breast cancer cell proliferation and metastasis through IL6/JAK2/PI3K pathway. Biochem Pharmacol. 2020;172:113752 pubmed publisher
Zhang Z, Liu R, Shuai Y, Huang Y, Jin R, Wang X, et al. ASCT2 (SLC1A5)-dependent glutamine uptake is involved in the progression of head and neck squamous cell carcinoma. Br J Cancer. 2020;122:82-93 pubmed publisher
Xu D, Liu J, Ma H, Guo W, Wang J, Kan X, et al. Schisandrin A protects against lipopolysaccharide-induced mastitis through activating Nrf2 signaling pathway and inducing autophagy. Int Immunopharmacol. 2020;78:105983 pubmed publisher
Hussain T, Zhao D, Shah S, Sabir N, Wang J, Liao Y, et al. PP2Ac Modulates AMPK-Mediated Induction of Autophagy in Mycobacterium bovis-Infected Macrophages. Int J Mol Sci. 2019;20: pubmed publisher
Luo J, Long Y, Ren G, Zhang Y, Chen J, Huang R, et al. Punicalagin Reversed the Hepatic Injury of Tetrachloromethane by Antioxidation and Enhancement of Autophagy. J Med Food. 2019;22:1271-1279 pubmed publisher
Zhou C, Qian X, Hu M, Zhang R, Liu N, Huang Y, et al. STYK1 promotes autophagy through enhancing the assembly of autophagy-specific class III phosphatidylinositol 3-kinase complex I. Autophagy. 2019;:1-21 pubmed publisher
Irungbam K, Churin Y, Matono T, Weglage J, Ocker M, Glebe D, et al. Cannabinoid receptor 1 knockout alleviates hepatic steatosis by downregulating perilipin 2. Lab Invest. 2019;: pubmed publisher
Liang J, Zhou F, Xiong X, Zhang X, Li S, Li X, et al. Enhancing the retrograde axonal transport by curcumin promotes autophagic flux in N2a/APP695swe cells. Aging (Albany NY). 2019;11:7036-7050 pubmed publisher
Wang Z, Li C, Li Y, Guo X, Yan Z, Gao F, et al. DpdtbA-Induced Growth Inhibition in Human Esophageal Cancer Cells Involved Inactivation of the p53/EGFR/AKT Pathway. Oxid Med Cell Longev. 2019;2019:5414670 pubmed publisher
Qian L, Zhu K, Lin Y, An L, Huang F, Yao Y, et al. Insulin secretion impairment induced by rosuvastatin partly though autophagy in INS-1E cells. Cell Biol Int. 2019;: pubmed publisher
Jia J, Gong X, Zhao Y, Yang Z, Ji K, Luan T, et al. Autophagy Enhancing Contributes to the Organ Protective Effect of Alpha-Lipoic Acid in Septic Rats. Front Immunol. 2019;10:1491 pubmed publisher
Li T, Wen L, Cheng B. Cordycepin alleviates hepatic lipid accumulation by inducing protective autophagy via PKA/mTOR pathway. Biochem Biophys Res Commun. 2019;516:632-638 pubmed publisher
Jin J, Sun H, Liu D, Wang H, Liu Q, Chen H, et al. LRG1 Promotes Apoptosis and Autophagy through the TGFβ-smad1/5 Signaling Pathway to Exacerbate Ischemia/Reperfusion Injury. Neuroscience. 2019;: pubmed publisher
Wen J, Xu B, Sun Y, Lian M, Li Y, Lin Y, et al. Paeoniflorin protects against intestinal ischemia/reperfusion by activating LKB1/AMPK and promoting autophagy. Pharmacol Res. 2019;146:104308 pubmed publisher
Zhang C, Zhan J, Zhao M, Dai H, Deng Y, Zhou W, et al. Protective mechanism of Taxifolin for chlorpyrifos neurotoxicity in BV2 cells. Neurotoxicology. 2019;74:74-80 pubmed publisher
Hussain T, Zhao D, Shah S, Sabir N, Wang J, Liao Y, et al. Nilotinib: A Tyrosine Kinase Inhibitor Mediates Resistance to Intracellular Mycobacterium Via Regulating Autophagy. Cells. 2019;8: pubmed publisher
Bian X, Bai Y, Su X, Zhao G, Sun G, Li D. Knockdown of periostin attenuates 5/6 nephrectomy-induced intrarenal renin-angiotensin system activation, fibrosis, and inflammation in rats. J Cell Physiol. 2019;234:22857-22873 pubmed publisher
Qu L, Chen C, He W, Chen Y, Li Y, Wen Y, et al. Glycyrrhizic acid ameliorates LPS-induced acute lung injury by regulating autophagy through the PI3K/AKT/mTOR pathway. Am J Transl Res. 2019;11:2042-2055 pubmed
Sabir N, Hussain T, Liao Y, Wang J, Song Y, Shahid M, et al. Kallikrein 12 Regulates Innate Resistance of Murine Macrophages against Mycobacterium bovis Infection by Modulating Autophagy and Apoptosis. Cells. 2019;8: pubmed publisher
Liu X, Zhao P, Wang X, Wang L, Zhu Y, Song Y, et al. Celastrol mediates autophagy and apoptosis via the ROS/JNK and Akt/mTOR signaling pathways in glioma cells. J Exp Clin Cancer Res. 2019;38:184 pubmed publisher
Wang Y, Han T, Gan M, Guo M, Xie C, Jin J, et al. A novel function of anaphase promoting complex subunit 10 in tumor progression in non-small cell lung cancer. Cell Cycle. 2019;18:1019-1032 pubmed publisher
Sun J, Feng Y, Wang Y, Ji Q, Cai G, Shi L, et al. α-hederin induces autophagic cell death in colorectal cancer cells through reactive oxygen species dependent AMPK/mTOR signaling pathway activation. Int J Oncol. 2019;54:1601-1612 pubmed publisher
Wu D, Zhong P, Wang J, Wang H. Exogenous hydrogen sulfide mitigates LPS + ATP-induced inflammation by inhibiting NLRP3 inflammasome activation and promoting autophagy in L02 cells. Mol Cell Biochem. 2019;457:145-156 pubmed publisher
Ji L, Gao J, Kong R, Gao Y, Ji X, Zhao D. Autophagy exerts pivotal roles in regulatory effects of 1α,25-(OH)2D3 on the osteoclastogenesis. Biochem Biophys Res Commun. 2019;511:869-874 pubmed publisher
Pan H, Wang H, Yu J, Huang X, Hao Y, Zhang C, et al. Near-infrared light remotely up-regulate autophagy with spatiotemporal precision via upconversion optogenetic nanosystem. Biomaterials. 2019;199:22-31 pubmed publisher
Wang Y, Meng C, Zhang J, Wu J, Zhao J. Inhibition of GSK-3β alleviates cerebral ischemia/reperfusion injury in rats by suppressing NLRP3 inflammasome activation through autophagy. Int Immunopharmacol. 2019;68:234-241 pubmed publisher
Wu J, Zhou Y, Yuan Z, Yi J, Chen J, Wang N, et al. Autophagy and Apoptosis Interact to Modulate T-2 Toxin-Induced Toxicity in Liver Cells. Toxins (Basel). 2019;11: pubmed publisher
Wang H, Zhao Z, Lei S, Li S, Xiang Z, Wang X, et al. Gambogic acid induces autophagy and combines synergistically with chloroquine to suppress pancreatic cancer by increasing the accumulation of reactive oxygen species. Cancer Cell Int. 2019;19:7 pubmed publisher
Zhang M, Shi R, Zhang Y, Shan H, Zhang Q, Yang X, et al. Nix/BNIP3L-dependent mitophagy accounts for airway epithelial cell injury induced by cigarette smoke. J Cell Physiol. 2019;234:14210-14220 pubmed publisher
Liu Y, Liu B, Li Y, Li Y, Du J, Deng S, et al. Autophagy is involved in the differentiation of epicardial progenitor cells into vascular smooth muscle cells in mice. Exp Cell Res. 2019;375:60-71 pubmed publisher
Ma Z, Li F, Chen L, Gu T, Zhang Q, Qu Y, et al. Autophagy promotes hepatic differentiation of hepatic progenitor cells by regulating the Wnt/β-catenin signaling pathway. J Mol Histol. 2019;50:75-90 pubmed publisher
Liu L, Xie P, Li W, Wu Y, An W. Augmenter of Liver Regeneration Protects against Ethanol-Induced Acute Liver Injury by Promoting Autophagy. Am J Pathol. 2019;189:552-567 pubmed publisher
Zhang X, Liu J, Gu Y, Sun C, Qu F. Down-regulation of lncRNA OGFRP1 induces autophagy and growth inhibition by AKT/mTOR signaling pathway in HCAECs. Cell Biol Int. 2019;43:158-166 pubmed publisher
Wang C, Fu J, Wang M, Cai Y, Hua X, Du Y, et al. Bartonella quintana type IV secretion effector BepE-induced selective autophagy by conjugation with K63 polyubiquitin chain. Cell Microbiol. 2019;21:e12984 pubmed publisher
Duan J, Deng T, Kang J, Chen M. DINP aggravates autoimmune thyroid disease through activation of the Akt/mTOR pathway and suppression of autophagy in Wistar rats. Environ Pollut. 2019;245:316-324 pubmed publisher
Yeganeh B, Lee J, Bilodeau C, Lok I, Ermini L, Ackerley C, et al. Acid Sphingomyelinase Inhibition Attenuates Cell Death in Mechanically Ventilated Newborn Rat Lung. Am J Respir Crit Care Med. 2019;199:760-772 pubmed publisher
Li M, Xu M, Li J, Chen L, Xu D, Tong Y, et al. Alda-1 Ameliorates Liver Ischemia-Reperfusion Injury by Activating Aldehyde Dehydrogenase 2 and Enhancing Autophagy in Mice. J Immunol Res. 2018;2018:9807139 pubmed publisher
Zhang X, Liu H, Hao Y, Xu L, Zhang T, Liu Y, et al. Coenzyme Q10 protects against hyperlipidemia-induced cardiac damage in apolipoprotein E-deficient mice. Lipids Health Dis. 2018;17:279 pubmed publisher
Dai C, Xiao X, Li D, Tun S, Wang Y, Velkov T, et al. Chloroquine ameliorates carbon tetrachloride-induced acute liver injury in mice via the concomitant inhibition of inflammation and induction of apoptosis. Cell Death Dis. 2018;9:1164 pubmed publisher
Deng L, Gao X, Liu B, He X, Xu J, Qiang J, et al. NMT1 inhibition modulates breast cancer progression through stress-triggered JNK pathway. Cell Death Dis. 2018;9:1143 pubmed publisher
Han T, Guo M, Gan M, Yu B, Tian X, Wang J. TRIM59 regulates autophagy through modulating both the transcription and the ubiquitination of BECN1. Autophagy. 2018;14:2035-2048 pubmed publisher
Sun D, Song C, Xu Y, Wang R, Liu W, Liu Z, et al. Involvement of PINK1/Parkin-mediated mitophagy in paraquat- induced apoptosis in human lung epithelial-like A549 cells. Toxicol In Vitro. 2018;53:148-159 pubmed publisher
Zhou Z, Niu Y, Huang G, Lu J, Chen A, Zhu L. Silencing of circRNA.2837 Plays a Protective Role in Sciatic Nerve Injury by Sponging the miR-34 Family via Regulating Neuronal Autophagy. Mol Ther Nucleic Acids. 2018;12:718-729 pubmed publisher
Wang L, Li X, Chen C. Inhibition of acetaminophen-induced hepatotoxicity in mice by exogenous thymosinβ4 treatment. Int Immunopharmacol. 2018;61:20-28 pubmed publisher
Guo X, Fu Y, Wang Z, Wang T, Li C, Huang T, et al. Di-2-pyridylhydrazone Dithiocarbamate Butyric Acid Ester Exerted Its Proliferative Inhibition against Gastric Cell via ROS-Mediated Apoptosis and Autophagy. Oxid Med Cell Longev. 2018;2018:4950705 pubmed publisher
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, et al. Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-? pathway in mice. Biomed Pharmacother. 2018;103:800-811 pubmed publisher
Tsai T, Lai K, Su J, Wu Y, Sheu J. 7-Acetylsinumaximol B Induces Apoptosis and Autophagy in Human Gastric Carcinoma Cells through Mitochondria Dysfunction and Activation of the PERK/eIF2α/ATF4/CHOP Signaling Pathway. Mar Drugs. 2018;16: pubmed publisher
Liu Y, Tang J, Liu D, Zhang L, He Y, Li J, et al. Increased autophagy in EOC re-ascites cells can inhibit cell death and promote drug resistance. Cell Death Dis. 2018;9:419 pubmed publisher
Wu Z, Zhu Q, Yin Y, Kang D, Cao R, Tian Q, et al. Traditional Chinese Medicine CFF-1 induced cell growth inhibition, autophagy, and apoptosis via inhibiting EGFR-related pathways in prostate cancer. Cancer Med. 2018;7:1546-1559 pubmed publisher
Matsubara S, Bokuda K, Asano Y, Morishima R, Sugaya K, Miyamoto K, et al. Mitophagy in three cases of immune-mediated necrotizing myopathy associated with anti-3-hydroxy-3-methylglutaryl-coenzyme A reductase autoantibodies: ultrastructural and immunohistochemical studies. Neuromuscul Disord. 2018;28:283-288 pubmed publisher
Li Z, Zhu S, Huang L, Shang M, Yu C, Zhu H, et al. Exendin-4 impairs the autophagic flux to induce apoptosis in pancreatic acinar AR42J cells by down-regulating LAMP-2. Biochem Biophys Res Commun. 2018;496:294-301 pubmed publisher
Niu Q, Chen J, Xia T, Li P, Zhou G, Xu C, et al. Excessive ER stress and the resulting autophagic flux dysfunction contribute to fluoride-induced neurotoxicity. Environ Pollut. 2018;233:889-899 pubmed publisher
Ghavami S, Yeganeh B, Zeki A, Shojaei S, Kenyon N, Ott S, et al. Autophagy and the unfolded protein response promote profibrotic effects of TGF-β1 in human lung fibroblasts. Am J Physiol Lung Cell Mol Physiol. 2018;314:L493-L504 pubmed publisher
Ren J, Liu Y, Li L, Zhao Y, Li Z, Wu C, et al. OAMDP, a novel podophyllotoxin derivative, induces apoptosis, cell cycle arrest and autophagy in hepatoma HepG2 cells. Cell Biol Int. 2018;42:194-204 pubmed publisher
Xu S, Niu P, Chen K, Xia Y, Yu Q, Liu N, et al. The liver protection of propylene glycol alginate sodium sulfate preconditioning against ischemia reperfusion injury: focusing MAPK pathway activity. Sci Rep. 2017;7:15175 pubmed publisher
Xue T, Ding X, Ji J, Yan H, Huang J, Guo X, et al. PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats. J Pharmacol Sci. 2017;135:105-113 pubmed publisher
Lv J, Yang L, Guo R, Shi Y, Zhang Z, Ye J. Ox-LDL-Induced MicroRNA-155 Promotes Autophagy in Human Endothelial Cells via Repressing the Rheb/ mTOR Pathway. Cell Physiol Biochem. 2017;43:1436-1448 pubmed publisher
Song Y, Kong L, Sun B, Gao L, Chu P, Ahsan A, et al. Induction of autophagy by an oleanolic acid derivative, SZC017, promotes ROS-dependent apoptosis through Akt and JAK2/STAT3 signaling pathway in human lung cancer cells. Cell Biol Int. 2017;41:1367-1378 pubmed publisher
Wu J, Tian Z, Sun Y, Lu C, Liu N, Gao Z, et al. Exogenous H2S facilitating ubiquitin aggregates clearance via autophagy attenuates type 2 diabetes-induced cardiomyopathy. Cell Death Dis. 2017;8:e2992 pubmed publisher
Zou J, Zhang Y, Sun J, Wang X, Tu H, Geng S, et al. Deoxyelephantopin Induces Reactive Oxygen Species-Mediated Apoptosis and Autophagy in Human Osteosarcoma Cells. Cell Physiol Biochem. 2017;42:1812-1821 pubmed publisher
Boeske A, Schwarten M, Ma P, Tusche M, Mötter J, Möller C, et al. Direct binding to GABARAP family members is essential for HIV-1 Nef plasma membrane localization. Sci Rep. 2017;7:5979 pubmed publisher
He Q, Li Z, Wang Y, Hou Y, Li L, Zhao J. Resveratrol alleviates cerebral ischemia/reperfusion injury in rats by inhibiting NLRP3 inflammasome activation through Sirt1-dependent autophagy induction. Int Immunopharmacol. 2017;50:208-215 pubmed publisher
Liu N, Wu J, Zhang L, Gao Z, Sun Y, Yu M, et al. Hydrogen Sulphide modulating mitochondrial morphology to promote mitophagy in endothelial cells under high-glucose and high-palmitate. J Cell Mol Med. 2017;21:3190-3203 pubmed publisher
Yang C, Ma X, Wang Z, Zeng X, Hu Z, Ye Z, et al. Curcumin induces apoptosis and protective autophagy in castration-resistant prostate cancer cells through iron chelation. Drug Des Devel Ther. 2017;11:431-439 pubmed publisher
Yu N, Xiong Y, Wang C. Bu-Zhong-Yi-Qi Decoction, the Water Extract of Chinese Traditional Herbal Medicine, Enhances Cisplatin Cytotoxicity in A549/DDP Cells through Induction of Apoptosis and Autophagy. Biomed Res Int. 2017;2017:3692797 pubmed publisher
Han T, Guo M, Zhang T, Gan M, Xie C, Wang J. A novel glutaminase inhibitor-968 inhibits the migration and proliferation of non-small cell lung cancer cells by targeting EGFR/ERK signaling pathway. Oncotarget. 2017;8:28063-28073 pubmed publisher
Hao H, Xia G, Wang C, Zhong F, Liu L, Zhang D. miR-106a suppresses tumor cells death in colorectal cancer through targeting ATG7. Med Mol Morphol. 2017;50:76-85 pubmed publisher
Wang Y, Yan J, Yin F, Li L, Qin Y, Meng C, et al. Role of autophagy in cadmium-induced testicular injury. Hum Exp Toxicol. 2017;36:1039-1048 pubmed publisher
Lu Y, Wang R, Dong Y, Tucker D, Zhao N, Ahmed M, et al. Low-level laser therapy for beta amyloid toxicity in rat hippocampus. Neurobiol Aging. 2017;49:165-182 pubmed publisher
Du J, Wang L, Wang Y, Shen J, Pan C, Meng Y, et al. Autophagy and apoptosis induced by Chinese giant salamander (Andrias davidianus) iridovirus (CGSIV). Vet Microbiol. 2016;195:87-95 pubmed publisher
Sun B, Gao L, Ahsan A, Chu P, Song Y, Li H, et al. Anticancer effect of SZC015 on lung cancer cells through ROS-dependent apoptosis and autophagy induction mechanisms in vitro. Int Immunopharmacol. 2016;40:400-409 pubmed publisher
Khan S, Zhao D, Shah S, Hassan M, Zhu T, Song Z, et al. Parkin Overexpression Ameliorates PrP106-126-Induced Neurotoxicity via Enhanced Autophagy in N2a Cells. Cell Mol Neurobiol. 2017;37:717-728 pubmed publisher
Guo Y, Dong S, Cui X, Feng Y, Liu T, Yin M, et al. Resveratrol alleviates MPTP-induced motor impairments and pathological changes by autophagic degradation of ?-synuclein via SIRT1-deacetylated LC3. Mol Nutr Food Res. 2016;60:2161-2175 pubmed publisher
Wang K, Zhang C, Bao J, Jia X, Liang Y, Wang X, et al. Synergistic chemopreventive effects of curcumin and berberine on human breast cancer cells through induction of apoptosis and autophagic cell death. Sci Rep. 2016;6:26064 pubmed publisher
Shi Q, Song X, Liu Z, Wang Y, Wang Y, Fu J, et al. Quinones Derived from Polychlorinated Biphenyls Induce ROS-Dependent Autophagy by Evoking an Autophagic Flux and Inhibition of mTOR/p70S6k. Chem Res Toxicol. 2016;29:1160-71 pubmed publisher
Kessel D, Evans C. Promotion of Proapoptotic Signals by Lysosomal Photodamage: Mechanistic Aspects and Influence of Autophagy. Photochem Photobiol. 2016;92:620-3 pubmed publisher
Su C, Niu P. Low doses of single or combined agrichemicals induces α-synuclein aggregation in nigrostriatal system of mice through inhibition of proteasomal and autophagic pathways. Int J Clin Exp Med. 2015;8:20508-15 pubmed
He G, Xu W, Tong L, Li S, Su S, Tan X, et al. Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis. 2016;21:390-403 pubmed publisher
Yeganeh B, Rezaei Moghadam A, Alizadeh J, Wiechec E, Alavian S, Hashemi M, et al. Hepatitis B and C virus-induced hepatitis: Apoptosis, autophagy, and unfolded protein response. World J Gastroenterol. 2015;21:13225-39 pubmed publisher
Wu J, Yang C, Guo C, Li X, Yang N, Zhao L, et al. SZC015, a synthetic oleanolic acid derivative, induces both apoptosis and autophagy in MCF-7 breast cancer cells. Chem Biol Interact. 2016;244:94-104 pubmed publisher
Yamani L, Li B, Larose L. Nck1 deficiency improves pancreatic β cell survival to diabetes-relevant stresses by modulating PERK activation and signaling. Cell Signal. 2015;27:2555-67 pubmed publisher
Dai C, Tang S, Velkov T, Xiao X. Colistin-Induced Apoptosis of Neuroblastoma-2a Cells Involves the Generation of Reactive Oxygen Species, Mitochondrial Dysfunction, and Autophagy. Mol Neurobiol. 2016;53:4685-700 pubmed publisher
Park M, Kim Y, Woo S, Lee H, Yu Y, Kim H, et al. Tonsil-derived mesenchymal stem cells ameliorate CCl4-induced liver fibrosis in mice via autophagy activation. Sci Rep. 2015;5:8616 pubmed publisher
Hiyama M, Kusakabe K, Takeshita A, Sugi S, Kuniyoshi N, Imai H, et al. Nutrient starvation affects expression of LC3 family at the feto-maternal interface during murine placentation. J Vet Med Sci. 2015;77:305-11 pubmed publisher
Zhu X, Ruan Z, Yang X, Chu K, Wu H, Li Y, et al. Connexin 31.1 degradation requires the Clathrin-mediated autophagy in NSCLC cell H1299. J Cell Mol Med. 2015;19:257-64 pubmed publisher
product information
CatalogNo :
18725-1-AP
AntigenName :
LC3B-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
microtubule-associated protein 1 light chain 3 beta
Immunogen :
Peptide
Species :
bovine, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
LC3, LC3B, LC3B-Specific, LC3-II, MAP1A/1BLC3, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, MAP1ALC3, MAP1LC3B
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_022818
Category :
Apoptosis;Autophagy;Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:200 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.