This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
AMPK alpha 2
catalog :
18167-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 15
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; human; loading ...; fig 5e
  • immunoprecipitation; human; loading ...; fig 5b
  • western blot; human; loading ...; fig 5a, 5c
Liu X, Ma F, Liu C, Zhu K, Li W, Xu Y, et al. UBE2O promotes the proliferation, EMT and stemness properties of breast cancer cells through the UBE2O/AMPKα2/mTORC1-MYC positive feedback loop. Cell Death Dis. 2020;11:10 pubmed publisher
Zhao Y, Sun D, Chen Y, Zhan K, Meng Q, Zhang X, et al. Si-Miao-Yong-An Decoction attenuates isoprenaline-induced myocardial fibrosis in AMPK-driven Akt/mTOR and TGF-β/SMAD3 pathways. Biomed Pharmacother. 2020;130:110522 pubmed publisher
Cooper L, West R, Hayes C, Waddell D. Dual-specificity phosphatase 29 is induced during neurogenic skeletal muscle atrophy and attenuates glucocorticoid receptor activity in muscle cell culture. Am J Physiol Cell Physiol. 2020;319:C441-C454 pubmed publisher
Yang L, Cao H, Sun D, Lin L, Zheng W, Shen Z, et al. Normothermic Machine Perfusion Combined with Bone Marrow Mesenchymal Stem Cells Improves the Oxidative Stress Response and Mitochondrial Function in Rat Donation After Circulatory Death Livers. Stem Cells Dev. 2020;29:835-852 pubmed publisher
Meng Z, Liu Q, Sun F, Qiao L. Hepatitis C virus nonstructural protein 5A perturbs lipid metabolism by modulating AMPK/SREBP-1c signaling. Lipids Health Dis. 2019;18:191 pubmed publisher
Ji J, Xue T, Guo X, Yang J, Guo R, Wang J, et al. Antagonizing peroxisome proliferator-activated receptor γ facilitates M1-to-M2 shift of microglia by enhancing autophagy via the LKB1-AMPK signaling pathway. Aging Cell. 2018;17:e12774 pubmed publisher
Pan Y, Liu L, Li S, Wang K, Ke R, Shi W, et al. Activation of AMPK inhibits TGF-β1-induced airway smooth muscle cells proliferation and its potential mechanisms. Sci Rep. 2018;8:3624 pubmed publisher
Xue T, Ding X, Ji J, Yan H, Huang J, Guo X, et al. PD149163 induces hypothermia to protect against brain injury in acute cerebral ischemic rats. J Pharmacol Sci. 2017;135:105-113 pubmed publisher
Zhao Z, Zhang L, Guo X, Cao L, Xue T, Zhao X, et al. Rosiglitazone Exerts an Anti-depressive Effect in Unpredictable Chronic Mild-Stress-Induced Depressive Mice by Maintaining Essential Neuron Autophagy and Inhibiting Excessive Astrocytic Apoptosis. Front Mol Neurosci. 2017;10:293 pubmed publisher
Zhou S, Lu W, Chen L, Ge Q, Chen D, Xu Z, et al. AMPK deficiency in chondrocytes accelerated the progression of instability-induced and ageing-associated osteoarthritis in adult mice. Sci Rep. 2017;7:43245 pubmed publisher
Yuan H, Wang T, Niu Y, Liu X, Fu L. AMP-activated protein kinase-mediated expression of heat shock protein beta 1 enhanced insulin sensitivity in the skeletal muscle. FEBS Lett. 2017;591:97-108 pubmed publisher
Dong K, Wu M, Liu X, Huang Y, Zhang D, Wang Y, et al. Glutaredoxins concomitant with optimal ROS activate AMPK through S-glutathionylation to improve glucose metabolism in type 2 diabetes. Free Radic Biol Med. 2016;101:334-347 pubmed publisher
Liu L, Pan Y, Song Y, Su X, Ke R, Yang L, et al. Activation of AMPK ?2 inhibits airway smooth muscle cells proliferation. Eur J Pharmacol. 2016;791:235-243 pubmed publisher
Zhao L, Cui L, Jiang X, Zhang J, Zhu M, Jia J, et al. Extracellular pH regulates autophagy via the AMPK-ULK1 pathway in rat cardiomyocytes. FEBS Lett. 2016;590:3202-12 pubmed publisher
Ke R, Liu L, Zhu Y, Li S, Xie X, Li F, et al. Knockdown of AMPK?2 Promotes Pulmonary Arterial Smooth Muscle Cells Proliferation via mTOR/Skp2/p27(Kip1) Signaling Pathway. Int J Mol Sci. 2016;17: pubmed publisher
product information
CatalogNo :
18167-1-AP
AntigenName :
AMPK alpha 2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
protein kinase, AMP-activated, alpha 2 catalytic subunit
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AMPK, AMPK alpha 2, AMPK subunit alpha 2, AMPK2, AMPKA2, AMPKα2, PRKAA, PRKAA2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC069680
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Immunology;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.