PD-L1/CD274 | Proteintech Group 17952-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

PD-L1/CD274

catalog :

17952-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 37

Reference
Cai X, Wei B, Li L, Chen X, Liu W, Cui J, et al. Apatinib enhanced anti-PD-1 therapy for colon cancer in mice via promoting PD-L1 expression. Int Immunopharmacol. 2020;88:106858 pubmed publisher
Li Q, Qiu M, Yang S, Fang X, He X, Wang M, et al. Alpha-Fetoprotein Regulates the Expression of Immune-Related Proteins through the NF-κB (P65) Pathway in Hepatocellular Carcinoma Cells. J Oncol. 2020;2020:9327512 pubmed publisher
Song Y, Song W, Li Z, Song W, Wen Y, Li J, et al. CDC27 Promotes Tumor Progression and Affects PD-L1 Expression in T-Cell Lymphoblastic Lymphoma. Front Oncol. 2020;10:488 pubmed publisher
Ullah M, Meziani S, Shah S, Kaci R, Pimpie C, Pocard M, et al. Differentiation of cancer cells upregulates HLA‑G and PD‑L1. Oncol Rep. 2020;43:1797-1804 pubmed publisher
Zhang C, Asif H, Holt G, Griswold A, Campos M, Bejarano P, et al. Mycobacterium abscessus-Bronchial Epithelial Cells Cross-Talk Through Type I Interferon Signaling. Front Immunol. 2019;10:2888 pubmed publisher
Chen S, Li S, Shi D, Jiang W, Song M, Yang A, et al. Expression of PD-1/PD-L1 in head and neck squamous cell carcinoma and its clinical significance. Int J Biol Markers. 2019;34:398-405 pubmed publisher
D Alterio C, Buoncervello M, Ierano C, Napolitano M, Portella L, Rea G, et al. Targeting CXCR4 potentiates anti-PD-1 efficacy modifying the tumor microenvironment and inhibiting neoplastic PD-1. J Exp Clin Cancer Res. 2019;38:432 pubmed publisher
Osborne N, Sundseth R, Gay M, Cao H, Tucker R, Nadella S, et al. Vaccine against gastrin, a polyclonal antibody stimulator, decreases pancreatic cancer metastases. Am J Physiol Gastrointest Liver Physiol. 2019;317:G682-G693 pubmed publisher
Zhang C, Duan Y, Xia M, Dong Y, Chen Y, Zheng L, et al. TFEB mediates immune evasion and resistance to mTOR inhibition of renal cell carcinoma via induction of PD-L1. Clin Cancer Res. 2019;: pubmed publisher
Wan W, Qu C, Zhou Y, Zhang L, Chen M, Liu Y, et al. Doxorubicin and siRNA-PD-L1 co-delivery with T7 modified ROS-sensitive nanoparticles for tumor chemoimmunotherapy. Int J Pharm. 2019;566:731-744 pubmed publisher
Wang T, Chen S, Wang X, Huang Y, Qiu J, Fei Y, et al. Aberrant PD-1 ligand expression contributes to the myocardial inflammatory injury caused by Coxsackievirus B infection. Antiviral Res. 2019;166:1-10 pubmed publisher
Jin X, Ding D, Yan Y, Li H, Wang B, Ma L, et al. Phosphorylated RB Promotes Cancer Immunity by Inhibiting NF-κB Activation and PD-L1 Expression. Mol Cell. 2019;73:22-35.e6 pubmed publisher
Yang F, Zeng Z, Li J, Zheng Y, Wei F, Ren X. PD-1/PD-L1 Axis, Rather Than High-Mobility Group Alarmins or CD8+ Tumor-Infiltrating Lymphocytes, Is Associated With Survival in Head and Neck Squamous Cell Carcinoma Patients Who Received Surgical Resection. Front Oncol. 2018;8:604 pubmed publisher
Li J, Zhou Y, Chen W, Yuan Z, You B, Liu Y, et al. A Novel 3D in Vitro Tumor Model Based on Silk Fibroin/Chitosan Scaffolds To Mimic the Tumor Microenvironment. ACS Appl Mater Interfaces. 2018;10:36641-36651 pubmed publisher
Chen Q, Zhou R, Zhang Y, Zhu S, Xiao C, Gong J, et al. Bone marrow mesenchymal stromal cells attenuate liver allograft rejection may via upregulation PD-L1 expression through downregulation of miR-17-5p. Transpl Immunol. 2018;51:21-29 pubmed publisher
Dong P, Xiong Y, Yu J, Chen L, Tao T, Yi S, et al. Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer. Oncogene. 2018;37:5257-5268 pubmed publisher
Jia W, Jiang X, Liu W, Wang L, Zhu B, Zhu H, et al. Effects of three-dimensional collagen scaffolds on the expression profiles and biological functions of glioma cells. Int J Oncol. 2018;52:1787-1800 pubmed publisher
Ji X, Wang E, Tian F. MicroRNA-140 suppresses osteosarcoma tumor growth by enhancing anti-tumor immune response and blocking mTOR signaling. Biochem Biophys Res Commun. 2018;495:1342-1348 pubmed publisher
Takada K, Toyokawa G, Shoji F, Okamoto T, Maehara Y. The Significance of the PD-L1 Expression in Non-Small-Cell Lung Cancer: Trenchant Double Swords as Predictive and Prognostic Markers. Clin Lung Cancer. 2018;19:120-129 pubmed publisher
Kumar S, Davra V, Obr A, Geng K, Wood T, De Lorenzo M, et al. Crk adaptor protein promotes PD-L1 expression, EMT and immune evasion in a murine model of triple-negative breast cancer. Oncoimmunology. 2017;7:e1376155 pubmed publisher
Liu S, Chen S, Yuan W, Wang H, Chen K, Li D, et al. PD-1/PD-L1 interaction up-regulates MDR1/P-gp expression in breast cancer cells via PI3K/AKT and MAPK/ERK pathways. Oncotarget. 2017;8:99901-99912 pubmed publisher
Yang C, Lin M, Chang Y, Wu C. Globo H expression is associated with driver mutations and PD-L1 expressions in stage I non-small cell lung cancer. Cancer Biomark. 2017;21:211-220 pubmed publisher
Wang J, Xie T, Wang B, William W, Heymach J, El Naggar A, et al. PD-1 Blockade Prevents the Development and Progression of Carcinogen-Induced Oral Premalignant Lesions. Cancer Prev Res (Phila). 2017;10:684-693 pubmed publisher
Miao S, Mao X, Zhao S, Song K, Xiang C, Lv Y, et al. miR-217 inhibits laryngeal cancer metastasis by repressing AEG-1 and PD-L1 expression. Oncotarget. 2017;8:62143-62153 pubmed publisher
Buchakjian M, Merritt N, Moose D, Dupuy A, Tanas M, Henry M. A Trp53fl/flPtenfl/fl mouse model of undifferentiated pleomorphic sarcoma mediated by adeno-Cre injection and in vivo bioluminescence imaging. PLoS ONE. 2017;12:e0183469 pubmed publisher
Kikuchi M, Clump D, Srivastava R, Sun L, Zeng D, Diaz Perez J, et al. Preclinical immunoPET/CT imaging using Zr-89-labeled anti-PD-L1 monoclonal antibody for assessing radiation-induced PD-L1 upregulation in head and neck cancer and melanoma. Oncoimmunology. 2017;6:e1329071 pubmed publisher
Jia L, Xi Q, Wang H, Zhang Z, Liu H, Cheng Y, et al. miR-142-5p regulates tumor cell PD-L1 expression and enhances anti-tumor immunity. Biochem Biophys Res Commun. 2017;488:425-431 pubmed publisher
Wang K, Wang J, Wei F, Zhao N, Yang F, Ren X. Expression of TLR4 in Non-Small Cell Lung Cancer Is Associated with PD-L1 and Poor Prognosis in Patients Receiving Pulmonectomy. Front Immunol. 2017;8:456 pubmed publisher
Kim K, Kim J, Lee S, Lee E, Shin E, Seong J. Radiation improves antitumor effect of immune checkpoint inhibitor in murine hepatocellular carcinoma model. Oncotarget. 2017;8:41242-41255 pubmed publisher
Chen J, Li H, Pang R, Huang J. Altered status of programmed death-ligand 1 after recurrence in resected lung adenocarcinoma patients. Onco Targets Ther. 2017;10:2003-2007 pubmed publisher
Chang Y, Yang C, Huang Y, Wu C, Yang P. High PD-L1 expression is associated with stage IV disease and poorer overall survival in 186 cases of small cell lung cancers. Oncotarget. 2017;8:18021-18030 pubmed publisher
Hung J, Huang S, Shen Y, Wu Y, Chou T, Hsu W. WITHDRAWN: Prognostic Significance of Programmed Cell Death-Ligand 1 Expression in Patients With Resected Lung Adenocarcinoma. Ann Thorac Surg. 2016;: pubmed publisher
Lanzel E, Paula Gomez Hernandez M, Bates A, Treinen C, Starman E, Fischer C, et al. Predicting PD-L1 expression on human cancer cells using next-generation sequencing information in computational simulation models. Cancer Immunol Immunother. 2016;65:1511-1522 pubmed
Chang Y, Yang C, Lin M, Wu C, Yang P. High co-expression of PD-L1 and HIF-1? correlates with tumour necrosis in pulmonary pleomorphic carcinoma. Eur J Cancer. 2016;60:125-35 pubmed publisher
Yang C, Lin M, Chang Y, Wu C, Yang P. Programmed cell death-ligand 1 expression is associated with a favourable immune microenvironment and better overall survival in stage I pulmonary squamous cell carcinoma. Eur J Cancer. 2016;57:91-103 pubmed publisher
Jiang L, Zhao Z, Jiang S, Lin Y, Yang H, Xie Z, et al. Immunological markers predict the prognosis of patients with squamous non-small cell lung cancer. Immunol Res. 2015;62:316-24 pubmed publisher
Kao C, Wurz G, Lin Y, Vang D, Griffey S, Wolf M, et al. Assessing the Effects of Concurrent versus Sequential Cisplatin/Radiotherapy on Immune Status in Lung Tumor-Bearing C57BL/6 Mice. Cancer Immunol Res. 2015;3:741-50 pubmed publisher

product information

CatalogNo :

17952-1-AP

AntigenName :

PD-L1/CD274

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

CD274 molecule

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, FC, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

B7 H, B7 H1, B7 homolog 1, B7H1, CD274, CD274 molecule, PD L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL1, PD-L1, PD-L1/CD274, Programmed death ligand 1

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC074984

Category :

Binding Proteins;Cell Cycle;Immunology;Membrane Proteins;Signal transduction;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

FC 1:0 ; IF 1:25 ; IHC 1:600 ; IP 1:1000 ; WB 1:600 ;