This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
RAB27A
catalog :
17817-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 19
Reference
Hitomi K, Okada R, Loo T, Miyata K, Nakamura A, Takahashi A. DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses. Int J Mol Sci. 2020;21: pubmed publisher
Kanada M, Kim B, Hardy J, Ronald J, Bachmann M, Bernard M, et al. Microvesicle-mediated delivery of minicircle DNA results in effective gene-directed enzyme prodrug cancer therapy. Mol Cancer Ther. 2019;: pubmed publisher
Lan W, Pan S, Li H, Sun C, Chang X, Lu K, et al. Inhibition of the Notch1 Pathway Promotes the Effects of Nucleus Pulposus Cell-Derived Exosomes on the Differentiation of Mesenchymal Stem Cells into Nucleus Pulposus-Like Cells in Rats. Stem Cells Int. 2019;2019:8404168 pubmed publisher
Zou W, Lai M, Zhang Y, Zheng L, Xing Z, Li T, et al. Exosome Release Is Regulated by mTORC1. Adv Sci (Weinh). 2019;6:1801313 pubmed publisher
Wu X, Dai H, Liu L, Xu C, Yin Y, Yi J, et al. Citrate reduced oxidative damage in stem cells by regulating cellular redox signaling pathways and represent a potential treatment for oxidative stress-induced diseases. Redox Biol. 2019;21:101057 pubmed publisher
Datta A, Kim H, McGee L, Johnson A, Talwar S, Marugan J, et al. High-throughput screening identified selective inhibitors of exosome biogenesis and secretion: A drug repurposing strategy for advanced cancer. Sci Rep. 2018;8:8161 pubmed publisher
Matsumoto N, Sekiya M, Tohyama K, Ishiyama Matsuura E, Sun Wada G, Wada Y, et al. Essential Role of the a3 Isoform of V-ATPase in Secretory Lysosome Trafficking via Rab7 Recruitment. Sci Rep. 2018;8:6701 pubmed publisher
Tesi B, Rascon J, Chiang S, Burnyte B, Löfstedt A, Fasth A, et al. A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation. J Allergy Clin Immunol. 2018;142:317-321.e8 pubmed publisher
Liu S, Sahid M, Takemasa E, Maeyama K, Mogi M. Zoledronate modulates intracellular vesicle trafficking in mast cells via disturbing the interaction of myosinVa/Rab3a and sytaxin4/VAMP7. Biochem Pharmacol. 2018;151:18-25 pubmed publisher
Liu J, Gong X, Zhu X, Xue D, Liu Y, Wang P. Rab27A overexpression promotes bladder cancer proliferation and chemoresistance through regulation of NF-?B signaling. Oncotarget. 2017;8:75272-75283 pubmed publisher
Gomi H, Osawa H, Uno R, Yasui T, Hosaka M, Torii S, et al. Canine Salivary Glands: Analysis of Rab and SNARE Protein Expression and SNARE Complex Formation With Diverse Tissue Properties. J Histochem Cytochem. 2017;65:637-653 pubmed publisher
Fu Y, Zhang L, Zhang F, Tang T, Zhou Q, Feng C, et al. Exosome-mediated miR-146a transfer suppresses type I interferon response and facilitates EV71 infection. PLoS Pathog. 2017;13:e1006611 pubmed publisher
Datta A, Kim H, Lal M, McGee L, Johnson A, Moustafa A, et al. Manumycin A suppresses exosome biogenesis and secretion via targeted inhibition of Ras/Raf/ERK1/2 signaling and hnRNP H1 in castration-resistant prostate cancer cells. Cancer Lett. 2017;408:73-81 pubmed publisher
Chen Y, Fang Y, Cheng Y, Lin C, Hsu L, Wang S, et al. Exophagy of annexin A2 via RAB11, RAB8A and RAB27A in IFN-γ-stimulated lung epithelial cells. Sci Rep. 2017;7:5676 pubmed publisher
Takahashi A, Okada R, Nagao K, Kawamata Y, Hanyu A, Yoshimoto S, et al. Exosomes maintain cellular homeostasis by excreting harmful DNA from cells. Nat Commun. 2017;8:15287 pubmed publisher
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed publisher
Smallwood D, Apollonio B, Willimott S, Lezina L, Alharthi A, Ambrose A, et al. Extracellular vesicles released by CD40/IL-4-stimulated CLL cells confer altered functional properties to CD4+ T cells. Blood. 2016;128:542-52 pubmed publisher
Wang H, Cui Q, Zhang T, Wang Z, Ouyang Y, Shen W, et al. Rab3A, Rab27A, and Rab35 regulate different events during mouse oocyte meiotic maturation and activation. Histochem Cell Biol. 2016;145:647-57 pubmed publisher
Gomi H, Morikawa S, Shinmura N, Moki H, Yasui T, Tsukise A, et al. Expression of Secretogranin III in Chicken Endocrine Cells: Its Relevance to the Secretory Granule Properties of Peptide Prohormone Processing and Bioactive Amine Content. J Histochem Cytochem. 2015;63:350-66 pubmed publisher
product information
CatalogNo :
17817-1-AP
AntigenName :
RAB27A
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
RAB27A, member RAS oncogene family
Immunogen :
Recombinant Protein
Species :
chicken, dog, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
GS2, GTP binding protein Ram, HsT18676, Rab 27, RAB27, RAB27A, RAM, Ras related protein Rab 27A
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC107680
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Neurology;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.