INPP5E | Proteintech Group 17797-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

INPP5E

catalog :

17797-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 23

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:500; loading ...; fig 2c	Han S, Miyoshi K, Shikada S, Amano G, Wang Y, Yoshimura T, et al. TULP3 is required for localization of membrane-associated proteins ARL13B and INPP5E to primary cilia. Biochem Biophys Res Commun. 2018;: pubmed publisher
western blot; mouse; loading ...; fig 3g immunocytochemistry; human; loading ...; fig 7a western blot; human; loading ...; fig 2c	Sierra Potchanant E, Cerabona D, Sater Z, He Y, Sun Z, Gehlhausen J, et al. INPP5E Preserves Genomic Stability through Regulation of Mitosis. Mol Cell Biol. 2017;37: pubmed publisher
immunocytochemistry; human; 1:500; fig 1b western blot; human; 1:5000; fig 4c	Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed publisher
immunocytochemistry; mouse; 1:2000; fig s3 western blot; mouse; 1:1000; fig s3 immunocytochemistry; human; 1:2000; fig 4	Slaats G, Isabella C, Kroes H, Dempsey J, Gremmels H, Monroe G, et al. MKS1 regulates ciliary INPP5E levels in Joubert syndrome. J Med Genet. 2016;53:62-72 pubmed publisher
	Gerakopoulos V, Ngo P, Tsiokas L. Loss of polycystins suppresses deciliation via the activation of the centrosomal integrity pathway. Life Sci Alliance. 2020;3: pubmed publisher
	Wang W, Allard B, Pottorf T, Wang H, Vivian J, Tran P. Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis. FASEB J. 2020;34:6369-6381 pubmed publisher
	Gigante E, Taylor M, Ivanova A, Kahn R, Caspary T. ARL13B regulates Sonic hedgehog signaling from outside primary cilia. elife. 2020;9: pubmed publisher
	Frikstad K, Molinari E, Thoresen M, Ramsbottom S, Hughes F, Letteboer S, et al. A CEP104-CSPP1 Complex Is Required for Formation of Primary Cilia Competent in Hedgehog Signaling. Cell Rep. 2019;28:1907-1922.e6 pubmed publisher
	Giacalone J, Andorf J, Zhang Q, Burnight E, Ochoa D, Reutzel A, et al. Development of a Molecularly Stable Gene Therapy Vector for the Treatment of RPGR-associated X-linked Retinitis Pigmentosa. Hum Gene Ther. 2019;: pubmed publisher
	Bhattarai S, Begum S, Popow R, Ezratty E. The ciliary GTPase Arl3 maintains tissue architecture by directing planar spindle orientation during epidermal morphogenesis. Development. 2019;146: pubmed publisher
	Hwang S, Somatilaka B, Badgandi H, Palicharla V, Walker R, Shelton J, et al. Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia. Curr Biol. 2019;29:790-802.e5 pubmed publisher
	Zhang Q, Giacalone J, Searby C, Stone E, Tucker B, Sheffield V. Disruption of RPGR protein interaction network is the common feature of RPGR missense variations that cause XLRP. Proc Natl Acad Sci U S A. 2019;116:1353-1360 pubmed publisher
	Alkanderi S, Molinari E, Shaheen R, Elmaghloob Y, Stephen L, Sammut V, et al. ARL3 Mutations Cause Joubert Syndrome by Disrupting Ciliary Protein Composition. Am J Hum Genet. 2018;103:612-620 pubmed publisher
	Abdelhamed Z, Ryan T, Fuller M, Coulson Gilmer C, Abdelmottaleb D, Wang T, et al. Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma. Int J Gynecol Cancer. 2018;28:1535-1544 pubmed publisher
	Hanke Gogokhia C, Wu Z, Sharif A, Yazigi H, Frederick J, Baehr W. The guanine nucleotide exchange factor Arf-like protein 13b is essential for assembly of the mouse photoreceptor transition zone and outer segment. J Biol Chem. 2017;292:21442-21456 pubmed publisher
	Goetz S, Bangs F, Barrington C, Katsanis N, Anderson K. The Meckel syndrome- associated protein MKS1 functionally interacts with components of the BBSome and IFT complexes to mediate ciliary trafficking and hedgehog signaling. PLoS ONE. 2017;12:e0173399 pubmed publisher
	Schou K, Mogensen J, Morthorst S, Nielsen B, Aleliunaite A, Serra Marques A, et al. KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling. Nat Commun. 2017;8:14177 pubmed publisher
	Nozaki S, Katoh Y, Terada M, Michisaka S, Funabashi T, Takahashi S, et al. Regulation of ciliary retrograde protein trafficking by the Joubert syndrome proteins ARL13B and INPP5E. J Cell Sci. 2017;130:563-576 pubmed publisher
	Fu W, Wang L, Kim S, Li J, Dynlacht B. Role for the IFT-A Complex in Selective Transport to the Primary Cilium. Cell Rep. 2016;17:1505-1517 pubmed publisher
	Xu W, Jin M, Hu R, Wang H, Zhang F, Yuan S, et al. The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane. J Am Soc Nephrol. 2017;28:118-129 pubmed publisher
	Hakim S, Dyson J, Feeney S, Davies E, Sriratana A, Koenig M, et al. Inpp5e suppresses polycystic kidney disease via inhibition of PI3K/Akt-dependent mTORC1 signaling. Hum Mol Genet. 2016;25:2295-2313 pubmed
	Yang A, Sachs A, Nystuen A. Deletion of Inpp5a causes ataxia and cerebellar degeneration in mice. Neurogenetics. 2015;16:277-85 pubmed publisher
	Plotnikova O, Seo S, Cottle D, Conduit S, Hakim S, Dyson J, et al. INPP5E interacts with AURKA, linking phosphoinositide signaling to primary cilium stability. J Cell Sci. 2015;128:364-72 pubmed publisher

product information

CatalogNo :

17797-1-AP

AntigenName :

INPP5E

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

inositol polyphosphate-5-phosphatase, 72 kDa

Immunogen :

Recombinant Protein

Species :

human, mouse, rat, zebrafish

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IP, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

INPP5E, PPI5PIV

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.02% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC028032

Category :

Cytoskeleton/Scaffold Proteins;Membrane Proteins;Metabolism;Signal transduction;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IF 1:50 ; IHC 1:50 ; IP 1:1000 ; WB 1:1000 ;