This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Synaptophysin
catalog :
17785-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, immunohistochemistry - paraffin section
citations: 36
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 7a
Zhou C, Sun X, Hu Y, Song J, Dong S, Kong D, et al. Genomic deletion of TLR2 induces aggravated white matter damage and deteriorated neurobehavioral functions in mouse models of Alzheimer's disease. Aging (Albany NY). 2019;11:7257-7273 pubmed publisher
  • immunohistochemistry - paraffin section; mouse; loading ...; fig 5f
Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn L, Rosenthal B, et al. A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019;176:790-804.e13 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig s17b
Deng H, Shi Y, Yang Y, Ahmeti K, Miller N, Huang C, et al. Identification of TMEM230 mutations in familial Parkinson's disease. Nat Genet. 2016;48:733-9 pubmed publisher
Sun Y, He L, Wang T, Hua W, Qin H, Wang J, et al. Activation of p62-Keap1-Nrf2 Pathway Protects 6-Hydroxydopamine-Induced Ferroptosis in Dopaminergic Cells. Mol Neurobiol. 2020;: pubmed publisher
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, et al. Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells. Toxicol In Vitro. 2020;67:104911 pubmed publisher
Liu Y, Zou G, Tu B, Hu Z, Luo C, Cui Y, et al. Corticosterone Induced the Increase of proBDNF in Primary Hippocampal Neurons Via Endoplasmic Reticulum Stress. Neurotox Res. 2020;38:370-384 pubmed publisher
Escande Beillard N, Loh A, Saleem S, Kanata K, Hashimoto Y, Altunoglu U, et al. Loss of PYCR2 Causes Neurodegeneration by Increasing Cerebral Glycine Levels via SHMT2. Neuron. 2020;107:82-94.e6 pubmed publisher
Asamitsu S, Imai Y, Yabuki Y, Ikenoshita S, Takeuchi M, Kashiwagi H, et al. Identification and immunohistochemical characterization of G-quadruplexes in mouse brain. Biochem Biophys Res Commun. 2020;: pubmed publisher
Zhang J, Xiao B, Li C, Wang Y. Fingolimod (FTY720) improves postoperative cognitive dysfunction in mice subjected to D-galactose-induced aging. Neural Regen Res. 2020;15:1308-1315 pubmed publisher
Wang X, Song Y, Chen J, Zhang S, Le Y, Xie Z, et al. Subcutaneous administration of β-hydroxybutyrate improves learning and memory of sepsis surviving mice. Neurotherapeutics. 2019;: pubmed publisher
Shi B, Luo J, Fang Y, Liu X, Rao Z, Liu R, et al. Xiaoyao Pills Prevent Lipopolysaccharide-Induced Depression by Inhibiting Inflammation and Protecting Nerves. Front Pharmacol. 2019;10:1324 pubmed publisher
Yang J, Zhang L, Cao L, Qi J, Li P, Wang X, et al. MicroRNA-99a is a Potential Target for Regulating Hypothalamic Synaptic Plasticity in the Peri/Postmenopausal Depression Model. Cells. 2019;8: pubmed publisher
Guo S, Zhen Y, Zhu Z, Zhou G, Zheng X. Cinnamic acid rescues behavioral deficits in a mouse model of traumatic brain injury by targeting miR-455-3p/HDAC2. Life Sci. 2019;235:116819 pubmed publisher
Raihan O, Brishti A, Li Q, Zhang Q, Li D, Li X, et al. SFRS11 Loss Leads to Aging-Associated Cognitive Decline by Modulating LRP8 and ApoE. Cell Rep. 2019;28:78-90.e6 pubmed publisher
Li P, Guo Y, Ding P, Liu R, Deng F, Feng X, et al. Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats. Neurol Res. 2019;:1-8 pubmed publisher
Singh M, Garrison J, Wang K, Sheffield V. Absence of BBSome function leads to astrocyte reactivity in the brain. Mol Brain. 2019;12:48 pubmed publisher
Shah S, Zhao D, Taglialatela G, Hussain T, Dong H, Sabir N, et al. Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway. Int J Mol Sci. 2019;20: pubmed publisher
Lan Y, Sullivan P, Hu F. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. Autophagy. 2019;15:871-885 pubmed publisher
Ge Y, Song X, Chen L, Hu D, Hua L, Cui Y, et al. Cadmium induces actin cytoskeleton alterations and dysfunction in Neuro-2a cells. Environ Toxicol. 2019;34:469-475 pubmed publisher
Mo J, Wang B, Zhu X, Wu X, Liu Y. PRRT2 deficiency induces paroxysmal kinesigenic dyskinesia by influencing synaptic function in the primary motor cortex of rats. Neurobiol Dis. 2019;121:274-285 pubmed publisher
Jiang P, Li G, Zhou X, Wang C, Qiao Y, Liao D, et al. Chronic fluoride exposure induces neuronal apoptosis and impairs neurogenesis and synaptic plasticity: Role of GSK-3β/β-catenin pathway. Chemosphere. 2019;214:430-435 pubmed publisher
Zhong F, Liu L, Wei J, Hu Z, Li L, Wang S, et al. Brain-Derived Neurotrophic Factor Precursor in the Hippocampus Regulates Both Depressive and Anxiety-Like Behaviors in Rats. Front Psychiatry. 2018;9:776 pubmed publisher
Wang L, Pei S, Han L, Guo B, Li Y, Duan R, et al. Mesenchymal Stem Cell-Derived Exosomes Reduce A1 Astrocytes via Downregulation of Phosphorylated NFκB P65 Subunit in Spinal Cord Injury. Cell Physiol Biochem. 2018;50:1535-1559 pubmed publisher
Zhu L, Tang T, Fan R, Luo J, Cui H, Zhang C, et al. Xuefu Zhuyu decoction improves neurological dysfunction by increasing synapsin expression after traumatic brain injury. Neural Regen Res. 2018;13:1417-1424 pubmed publisher
Liu Q, Tong D, Liu G, Gao J, Wang L, Xu J, et al. Metformin Inhibits Prostate Cancer Progression by Targeting Tumor-Associated Inflammatory Infiltration. Clin Cancer Res. 2018;24:5622-5634 pubmed publisher
Reddy P, Yin X, Manczak M, Kumar S, Pradeepkiran J, Vijayan M, et al. Mutant APP and amyloid beta-induced defective autophagy, mitophagy, mitochondrial structural and functional changes and synaptic damage in hippocampal neurons from Alzheimer's disease. Hum Mol Genet. 2018;27:2502-2516 pubmed publisher
Stallings N, O Neal M, Hu J, Kavalali E, Bezprozvanny I, Malter J. Pin1 mediates A?42-induced dendritic spine loss. Sci Signal. 2018;11: pubmed publisher
Brock J, Graham L, Staufenberg E, Im S, Tuszynski M. Rodent Neural Progenitor Cells Support Functional Recovery after Cervical Spinal Cord Contusion. J Neurotrauma. 2018;35:1069-1078 pubmed publisher
Zeng H, Yu F, Zhang Z, Yang Q, Jin S, He X, et al. Quantitative proteomics study of host response to virulent and attenuated pseudorabies virus infection in mouse brain. Biochim Biophys Acta Proteins Proteom. 2018;1866:307-315 pubmed publisher
Zhang S, Wang X, Ai S, Ouyang W, Le Y, Tong J. Sepsis-induced selective loss of NMDA receptors modulates hippocampal neuropathology in surviving septic mice. PLoS ONE. 2017;12:e0188273 pubmed publisher
Wang B, Jin X, Kuang X, Tian S. Chronic administration of parecoxib exerts anxiolytic-like and memory enhancing effects and modulates synaptophysin expression in mice. BMC Anesthesiol. 2017;17:152 pubmed publisher
Kuruva C, Manczak M, Yin X, Ogunmokun G, Reddy A, Reddy P. Aqua-soluble DDQ reduces the levels of Drp1 and A? and inhibits abnormal interactions between A? and Drp1 and protects Alzheimer's disease neurons from A?- and Drp1-induced mitochondrial and synaptic toxicities. Hum Mol Genet. 2017;26:3375-3395 pubmed publisher
Tang Y, Wang X, Zhang S, Duan S, Qing W, Chen G, et al. Pre-existing weakness is critical for the occurrence of postoperative cognitive dysfunction in mice of the same age. PLoS ONE. 2017;12:e0182471 pubmed publisher
Chen L, Ning H, Yin Z, Song X, Feng Y, Qin H, et al. The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission. Chemosphere. 2017;185:589-594 pubmed publisher
Song Z, Shah S, Yang W, Dong H, Yang L, Zhou X, et al. Downregulation of the Repressor Element 1-Silencing Transcription Factor (REST) Is Associated with Akt-mTOR and Wnt-?-Catenin Signaling in Prion Diseases Models. Front Mol Neurosci. 2017;10:128 pubmed publisher
Shah S, Zhao D, Taglialatela G, Khan S, Hussain T, Dong H, et al. Early Minocycline and Late FK506 Treatment Improves Survival and Alleviates Neuroinflammation, Neurodegeneration, and Behavioral Deficits in Prion-Infected Hamsters. Neurotherapeutics. 2017;14:463-483 pubmed publisher
product information
CatalogNo :
17785-1-AP
AntigenName :
Synaptophysin
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
synaptophysin
Immunogen :
Recombinant Protein
Species :
hamster, hamsters, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
SYN, synaptophysin, SYP
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC064550
Category :
Binding Proteins;Membrane Proteins;Neurology;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:25 ; IHC 1:2000 ; IP 1:1000 ; WB 1:40000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.