This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IFT52
catalog :
17534-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunocytochemistry, immunoprecipitation
citations: 13
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 3b
Zhang W, Taylor S, Nevarez L, Lachman R, Nickerson D, Bamshad M, et al. IFT52 mutations destabilize anterograde complex assembly, disrupt ciliogenesis and result in short rib polydactyly syndrome. Hum Mol Genet. 2016;25:4012-4020 pubmed publisher
Vitre B, Taulet N, Guesdon A, Douanier A, Dosdane A, Cisneros M, et al. IFT proteins interact with HSET to promote supernumerary centrosome clustering in mitosis. EMBO Rep. 2020;21:e49234 pubmed publisher
Wang W, Allard B, Pottorf T, Wang H, Vivian J, Tran P. Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis. FASEB J. 2020;34:6369-6381 pubmed publisher
Liu C, He X, Liu W, Yang S, Wang L, Li W, et al. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. Am J Hum Genet. 2019;105:1168-1181 pubmed publisher
Dupont M, Humbert C, Huber C, Siour Q, Guerrera I, Jung V, et al. Human IFT52 mutations uncover a novel role for the protein in microtubule dynamics and centrosome cohesion. Hum Mol Genet. 2019;: pubmed publisher
Liu W, He X, Yang S, Zouari R, Wang J, Wu H, et al. Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice. Am J Hum Genet. 2019;104:738-748 pubmed publisher
Zhang Y, Chen Y, Zheng J, Wang J, Duan S, Zhang W, et al. Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat. J Mol Cell Biol. 2019;11:383-394 pubmed publisher
Honda A, Kita T, Seshadri S, Misaki K, Ahmed Z, Ladbury J, et al. FGFR1-mediated protocadherin-15 loading mediates cargo specificity during intraflagellar transport in inner ear hair-cell kinocilia. Proc Natl Acad Sci U S A. 2018;115:8388-8393 pubmed publisher
Takei R, Katoh Y, Nakayama K. Robust interaction of IFT70 with IFT52-IFT88 in the IFT-B complex is required for ciliogenesis. Biol Open. 2018;7: pubmed publisher
Silva L, Jacobs D, Allard B, Fields T, Sharma M, Wallace D, et al. Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells. Sci Rep. 2018;8:4985 pubmed publisher
Taulet N, Vitre B, Anguille C, Douanier A, Rocancourt M, Taschner M, et al. IFT proteins spatially control the geometry of cleavage furrow ingression and lumen positioning. Nat Commun. 2017;8:1928 pubmed publisher
Durán I, Taylor S, Zhang W, Martin J, Forlenza K, Spiro R, et al. Destabilization of the IFT-B cilia core complex due to mutations in IFT81 causes a Spectrum of Short-Rib Polydactyly Syndrome. Sci Rep. 2016;6:34232 pubmed publisher
Xu Y, Cao J, Huang S, Feng D, Zhang W, Zhu X, et al. Characterization of tetratricopeptide repeat-containing proteins critical for cilia formation and function. PLoS ONE. 2015;10:e0124378 pubmed publisher
product information
CatalogNo :
17534-1-AP
AntigenName :
IFT52
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
intraflagellar transport 52 homolog (Chlamydomonas)
Immunogen :
Recombinant Protein
Species :
chicken, dog, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IF, CoIP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
C20orf9, CGI 53, IFT52, NGD5, Protein NGD5 homolog
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC039831
Category :
Cytoskeleton/Scaffold Proteins;Development;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:25 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.