This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
RIPK1-Specific
catalog :
17519-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5b
Yuan Z, Zhang H, Hasnat M, Ding J, Chen X, Liang P, et al. A new perspective of triptolide-associated hepatotoxicity: Liver hypersensitivity upon LPS stimulation. Toxicology. 2019;414:45-56 pubmed publisher
  • immunoprecipitation; human; fig 6
  • western blot; human; 1:300; fig 4
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
Yang T, Fan T, Xu B. Norfloxacin induces apoptosis and necroptosis in human corneal epithelial cells. Toxicol In Vitro. 2020;66:104868 pubmed publisher
Wu K, Liu H, Wang Y, He J, Xu S, Chen Y, et al. SETDB1-Mediated Cell Fate Transition between 2C-Like and Pluripotent States. Cell Rep. 2020;30:25-36.e6 pubmed publisher
Lin Y, Yu M, Fan T. Insights into mechanisms of pranoprofen-induced apoptosis and necroptosis in human corneal stromal cells. Toxicol Lett. 2020;320:9-18 pubmed publisher
Shen B, Mei M, Pu Y, Zhang H, Liu H, Tang M, et al. Necrostatin-1 Attenuates Renal Ischemia and Reperfusion Injury via Meditation of HIF-1α/mir-26a/TRPC6/PARP1 Signaling. Mol Ther Nucleic Acids. 2019;17:701-713 pubmed publisher
Chang L, Wang Z, Ma F, Tran B, Zhong R, Xiong Y, et al. ZYZ-803 Mitigates Endoplasmic Reticulum Stress-Related Necroptosis after Acute Myocardial Infarction through Downregulating the RIP3-CaMKII Signaling Pathway. Oxid Med Cell Longev. 2019;2019:6173685 pubmed publisher
Li X, Peng Z, Zhou Y, Wang J, Lin X, Dong X, et al. Quetiapine induces myocardial necroptotic cell death through bidirectional regulation of cannabinoid receptors. Toxicol Lett. 2019;: pubmed publisher
Zhou Y, Jin H, Wu Y, Chen L, Bao X, Lu C. Gallic acid protects against ethanol-induced hepatocyte necroptosis via an NRF2-dependent mechanism. Toxicol In Vitro. 2019;57:226-232 pubmed publisher
Wang R, Dong Z, Zhang X, Mao J, Meng F, Lan X, et al. Evaluation of the Liver Toxicity of Pterocephalus hookeri Extract via Triggering Necrosis. Toxins (Basel). 2019;11: pubmed publisher
Guo F, Wu Q, Li P, Zheng L, Ye S, Dai X, et al. The role of the LncRNA-FA2H-2-MLKL pathway in atherosclerosis by regulation of autophagy flux and inflammation through mTOR-dependent signaling. Cell Death Differ. 2019;: pubmed publisher
Chen J, Jiang Z, Zhou X, Sun X, Cao J, Liu Y, et al. Dexmedetomidine Preconditioning Protects Cardiomyocytes Against Hypoxia/Reoxygenation-Induced Necroptosis by Inhibiting HMGB1-Mediated Inflammation. Cardiovasc Drugs Ther. 2019;33:45-54 pubmed publisher
Lôrincz T, Holczer M, Kapuy O, Szarka A. The Interrelationship of Pharmacologic Ascorbate Induced Cell Death and Ferroptosis. Pathol Oncol Res. 2019;25:669-679 pubmed publisher
Yan B, Zhang H, Dai T, Gu Y, Qiu X, Hu C, et al. Necrostatin-1 promotes ectopic periodontal tissue like structure regeneration in LPS-treated PDLSCs. PLoS ONE. 2018;13:e0207760 pubmed publisher
Jia Y, Wang F, Guo Q, Li M, Wang L, Zhang Z, et al. Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells. Redox Biol. 2018;19:375-387 pubmed publisher
Wu X, Guo Y, Min X, Pei L, Chen X. Neferine, a Bisbenzylisoquinoline Alkaloid, Ameliorates Dextran Sulfate Sodium-Induced Ulcerative Colitis. Am J Chin Med. 2018;46:1263-1279 pubmed publisher
Hu J, Wang H, Gu J, Liu X, Zhou X. Trail armed oncolytic poxvirus suppresses lung cancer cell by inducing apoptosis. Acta Biochim Biophys Sin (Shanghai). 2018;50:1018-1027 pubmed publisher
Yan B, Wei K, Hou L, Dai T, Gu Y, Qiu X, et al. Receptor-Interacting Protein 3/Caspase-8 May Regulate Inflammatory Response and Promote Tissue Regeneration in the Periodontal Microenvironment. Med Sci Monit. 2018;24:5247-5257 pubmed publisher
Wang Y, Shan B, Liang Y, Wei H, Yuan J. Parkin regulates NF-?B by mediating site-specific ubiquitination of RIPK1. Cell Death Dis. 2018;9:732 pubmed publisher
Guo Y, Wu X, Wu Q, Lu Y, Shi J, Chen X. Dihydrotanshinone I, a natural product, ameliorates DSS-induced experimental ulcerative colitis in mice. Toxicol Appl Pharmacol. 2018;344:35-45 pubmed publisher
Hosen M, Militello G, Weirick T, Ponomareva Y, Dassanayaka S, Moore J, et al. Airn Regulates Igf2bp2 Translation in Cardiomyocytes. Circ Res. 2018;122:1347-1353 pubmed publisher
Yin S, Du W, Wang F, Han B, Cui Y, Yang D, et al. MicroRNA-326 sensitizes human glioblastoma cells to curcumin via the SHH/GLI1 signaling pathway. Cancer Biol Ther. 2018;19:260-270 pubmed publisher
Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida A, et al. Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis. Nat Commun. 2017;8:359 pubmed publisher
Liu H, Li X, Ning G, Zhu S, Ma X, Liu X, et al. The Machado-Joseph Disease Deubiquitinase Ataxin-3 Regulates the Stability and Apoptotic Function of p53. PLoS Biol. 2016;14:e2000733 pubmed publisher
Lu C, Xu W, Zhang F, Shao J, Zheng S. Nrf2 Knockdown Disrupts the Protective Effect of Curcumin on Alcohol-Induced Hepatocyte Necroptosis. Mol Pharm. 2016;13:4043-4053 pubmed
Wang H, Li M, Liu W, Yao G, Xia M, Hayashi T, et al. Gelatin promotes murine fibrosarcoma L929 cell detachment and protects the cells from TNF?-induced cytotoxicity. Connect Tissue Res. 2016;57:262-9 pubmed publisher
Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, et al. Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. Biol Reprod. 2016;94:31 pubmed publisher
Wang H, He W, Chen L, Liu W, Xu Q, Xia M, et al. Type I collagen gel protects murine fibrosarcoma L929 cells from TNFα-induced cell death. Biochem Biophys Res Commun. 2015;457:693-9 pubmed publisher
product information
CatalogNo :
17519-1-AP
AntigenName :
RIPK1-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
receptor (TNFRSF)-interacting serine-threonine kinase 1
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Cell death protein RIP, Receptor interacting protein 1, RIP, RIP 1, RIP1, RIPK1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_003804
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:25 ; IHC 1:200 ; IP 1:300 ; WB 1:300 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.