This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MAP2
catalog :
17490-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - frozen section, immunohistochemistry - free floating section
citations: 66
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; rat; fig s2d
Chen Y, Li J, Ma B, Li N, Wang S, Sun Z, et al. MSC-derived exosomes promote recovery from traumatic brain injury via microglia/macrophages in rat. Aging (Albany NY). 2020;12:18274-18296 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2f
Chen C, Chencheng Z, Cuiying L, Xiaokun G. Plasmacytoid Dendritic Cells Protect Against Middle Cerebral Artery Occlusion Induced Brain Injury by Priming Regulatory T Cells. Front Cell Neurosci. 2020;14:8 pubmed publisher
  • immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 6a
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
  • immunohistochemistry - free floating section; mouse; 1:500; loading ...; fig s1c
  • immunohistochemistry; mouse; 1:500; loading ...; fig 4a
Duan W, Guo M, Yi L, Zhang J, Bi Y, Liu Y, et al. Deletion of Tbk1 disrupts autophagy and reproduces behavioral and locomotor symptoms of FTD-ALS in mice. Aging (Albany NY). 2019;11:2457-2476 pubmed publisher
  • western blot; rat; 1:500; loading ...; fig 3a
Gao Y, Mruk D, Chen H, Lui W, Lee W, Cheng C. Regulation of the blood-testis barrier by a local axis in the testis: role of laminin ?2 in the basement membrane. FASEB J. 2017;31:584-597 pubmed publisher
Cone A, Hurwitz S, Lee G, Yuan X, Zhou Y, Li Y, et al. Alix and Syntenin-1 direct amyloid precursor protein trafficking into extracellular vesicles. BMC Mol Cell Biol. 2020;21:58 pubmed publisher
Liu Y, Wen D, Gao J, Xie B, Yu H, Shen Q, et al. Methamphetamine induces GSDME-dependent cell death in hippocampal neuronal cells through the endoplasmic reticulum stress pathway. Brain Res Bull. 2020;162:73-83 pubmed publisher
Goranci Buzhala G, Mariappan A, Gabriel E, Ramani A, Ricci Vitiani L, Buccarelli M, et al. Rapid and Efficient Invasion Assay of Glioblastoma in Human Brain Organoids. Cell Rep. 2020;31:107738 pubmed publisher
Yin Z, Hua L, Chen L, Hu D, Li J, An Z, et al. Bisphenol-A exposure induced neurotoxicity and associated with synapse and cytoskeleton in Neuro-2a cells. Toxicol In Vitro. 2020;67:104911 pubmed publisher
Liu Q, Tan Y, Qu T, Zhang J, Duan X, Xu H, et al. Therapeutic mechanism of human neural stem cell-derived extracellular vesicles against hypoxia-reperfusion injury in vitro. Life Sci. 2020;254:117772 pubmed publisher
Frew J, Baradaran Heravi A, Balgi A, Wu X, Yan T, Arns S, et al. Premature termination codon readthrough upregulates progranulin expression and improves lysosomal function in preclinical models of GRN deficiency. Mol Neurodegener. 2020;15:21 pubmed publisher
Cao H, Zhu X, Zhang J, Xu M, Ge L, Zhang C. Dose-dependent effects of tetramethylpyrazine on the characteristics of human umbilical cord mesenchymal stem cells for stroke therapy. Neurosci Lett. 2020;722:134797 pubmed publisher
Wang X, Xie S, Li Z, Ye Z, Gu X, Zhou L, et al. Generation of an iPSC line (HUSTi002-A) from fibroblasts of a patient with Sertoli cell-only syndrome carrying c.731_732delAT in PIWIL2 gene. Stem Cell Res. 2020;42:101703 pubmed publisher
Sun Y, Hei M, Fang Z, Tang Z, Wang B, Hu N. High-Mobility Group Box 1 Contributes to Cerebral Cortex Injury in a Neonatal Hypoxic-Ischemic Rat Model by Regulating the Phenotypic Polarization of Microglia. Front Cell Neurosci. 2019;13:506 pubmed publisher
Zhu Y, Fan Z, Wang R, Xie R, Guo H, Zhang M, et al. Single-Cell Analysis for Glycogen Localization and Metabolism in Cultured Astrocytes. Cell Mol Neurobiol. 2019;: pubmed publisher
Zhao R, Ying M, Gu S, Yin W, Li Y, Yuan H, et al. Cysteinyl Leukotriene Receptor 2 is Involved in Inflammation and Neuronal Damage by Mediating Microglia M1/M2 Polarization through NF-κB Pathway. Neuroscience. 2019;422:99-118 pubmed publisher
Xu B, Lang L, Lian S, Guo J, Wang J, Yang H, et al. Oxidation Stress-Mediated MAPK Signaling Pathway Activation Induces Neuronal Loss in the CA1 and CA3 Regions of the Hippocampus of Mice Following Chronic Cold Exposure. Brain Sci. 2019;9: pubmed publisher
Huang J, Yu C, Su M, Yang S, Zhang F, Chen Y, et al. Probucol, a "non-statin" cholesterol-lowering drug, ameliorates D-galactose induced cognitive deficits by alleviating oxidative stress via Keap1/Nrf2 signaling pathway in mice. Aging (Albany NY). 2019;11:8542-8555 pubmed publisher
He F, Dai R, Zhou X, Li X, Song X, Yan H, et al. Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed publisher
He G, Xu W, Liao H, Jiang C, Li C, Zhang W. Silencing Huwe1 reduces apoptosis of cortical neurons exposed to oxygen-glucose deprivation and reperfusion. Neural Regen Res. 2019;14:1977-1985 pubmed publisher
Wang K, Tian Y, Zhang Y, Li X, Wei X, Hu H, et al. Toxicity mechanism of sevoflurane in neural stem cells of rats through DNA methylation. Exp Ther Med. 2019;18:237-241 pubmed publisher
Li P, Guo Y, Ding P, Liu R, Deng F, Feng X, et al. Neuroprotective effects of a Smoothened receptor agonist against postoperative cognitive dysfunction by promoting autophagy in the dentate gyrus of aged rats. Neurol Res. 2019;:1-8 pubmed publisher
Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher
Li H. Restorative effect of modified dioscorea pills on the structure of hippocampal neurovascular unit in an animal model of chronic cerebral hypoperfusion. Heliyon. 2019;5:e01567 pubmed publisher
Zhu M, Hua Y, Tang J, Zhao X, Zhang L, Zhang Y. Lentiviral-mediated ephrin B2 gene modification of rat bone marrow mesenchymal stem cells. J Int Med Res. 2019;47:3282-3298 pubmed publisher
Ying X, Tu W, Li S, Wu Q, Chen X, Zhou Y, et al. Hyperbaric oxygen therapy reduces apoptosis and dendritic/synaptic degeneration via the BDNF/TrkB signaling pathways in SCI rats. Life Sci. 2019;: pubmed publisher
Corbridge S, Rice R, Bean L, Wuthrich C, Dang X, Nicholson D, et al. JC virus infection of meningeal and choroid plexus cells in patients with progressive multifocal leukoencephalopathy. J Neurovirol. 2019;: pubmed publisher
Chen M, Peng C, Maner R, Zulkefli N, Huang S, Hsieh C. Geniposide ameliorated fluoxetine-suppressed neurite outgrowth in Neuro2a neuroblastoma cells. Life Sci. 2019;226:1-11 pubmed publisher
Gao F, Gao K, He C, Liu M, Wan H, Wang P. Multi-site dynamic recording for Aβ oligomers-induced Alzheimer's disease in vitro based on neuronal network chip. Biosens Bioelectron. 2019;133:183-191 pubmed publisher
Xia Y, Zhang G, Han C, Ma K, Guo X, Wan F, et al. Microglia as modulators of exosomal alpha-synuclein transmission. Cell Death Dis. 2019;10:174 pubmed publisher
Wen Y, Wu K, Xie Y, Dan W, Zhan Y, Shi Q. Inhibitory effects of glucagon-like peptide-1 receptor on epilepsy. Biochem Biophys Res Commun. 2019;511:79-86 pubmed publisher
Wang Y, Zhang X, Tian J, Shan J, Hu Y, Zhai Y, et al. Talin promotes integrin activation accompanied by generation of tension in talin and an increase in osmotic pressure in neurite outgrowth. FASEB J. 2019;33:6311-6326 pubmed publisher
Zhong J, Lan C, Zhang C, Yang Y, Chen W, Zhang K, et al. Chondroitin sulfate proteoglycan represses neural stem/progenitor cells migration via PTPσ/α-actinin4 signaling pathway. J Cell Biochem. 2019;: pubmed publisher
Li X, Du X, Ni J. Zn2+ Aggravates Tau Aggregation and Neurotoxicity. Int J Mol Sci. 2019;20: pubmed publisher
Sun L, Zhou M, Liu C, Tang Y, Xiao K, Dai J, et al. Memantine can relieve the neuronal impairment caused by neurotropic virus infection. J Med Virol. 2019;91:935-940 pubmed publisher
Xie Q, Cheng J, Pan G, Wu S, Hu Q, Jiang H, et al. Treadmill exercise ameliorates focal cerebral ischemia/reperfusion-induced neurological deficit by promoting dendritic modification and synaptic plasticity via upregulating caveolin-1/VEGF signaling pathways. Exp Neurol. 2019;313:60-78 pubmed publisher
Fu J, Chen Z, Hu Y, Fan Z, Guo Z, Liang J, et al. A single factor induces neuronal differentiation to suppress glioma cell growth. CNS Neurosci Ther. 2019;25:486-495 pubmed publisher
Maxan A, Mason S, Saint Pierre M, Smith E, Ho A, Harrower T, et al. Outcome of cell suspension allografts in a patient with Huntington's disease. Ann Neurol. 2018;84:950-956 pubmed publisher
Lu L, Marisetty A, Liu B, Kamal M, Gumin J, Veo B, et al. REST overexpression in mice causes deficits in spontaneous locomotion. Sci Rep. 2018;8:12083 pubmed publisher
Mu T, Qin Y, Liu B, He X, Liao Y, Sun J, et al. In Vitro Neural Differentiation of Bone Marrow Mesenchymal Stem Cells Carrying the FTH1 Reporter Gene and Detection with MRI. Biomed Res Int. 2018;2018:1978602 pubmed publisher
Wang J, Zhang D, Fu X, Yu L, Lu Z, Gao Y, et al. Carbon monoxide-releasing molecule-3 protects against ischemic stroke by suppressing neuroinflammation and alleviating blood-brain barrier disruption. J Neuroinflammation. 2018;15:188 pubmed publisher
Cui X, Fu Z, Wang M, Nan X, Zhang B. Pitavastatin treatment induces neuroprotection through the BDNF-TrkB signalling pathway in cultured cerebral neurons after oxygen-glucose deprivation. Neurol Res. 2018;40:391-397 pubmed publisher
Zhang J, Tucker L, DongYan -, Lu Y, Yang L, Wu C, et al. Tert-butylhydroquinone post-treatment attenuates neonatal hypoxic-ischemic brain damage in rats. Neurochem Int. 2018;116:1-12 pubmed publisher
Ren H, Lv C, Xing Y, Geng Y, Zhang F, Bu W, et al. Downregulated Nuclear Factor E2-Related Factor 2 (Nrf2) Aggravates Cognitive Impairments via Neuroinflammation and Synaptic Plasticity in the Senescence-Accelerated Mouse Prone 8 (SAMP8) Mouse: A Model of Accelerated Senescence. Med Sci Monit. 2018;24:1132-1144 pubmed
Gilbert A, Chevez Barrios P, Cykowski M. Perineurial-like Cells and EMA Expression in the Suprachoroidal Region of the Human Eye. J Histochem Cytochem. 2018;66:367-375 pubmed publisher
Park J, Weldon B, Hong S, Workman T, Griffith W, Park J, et al. Characterization of 3D embryonic C57BL/6 and A/J mouse midbrain micromass in vitro culture systems for developmental neurotoxicity testing. Toxicol In Vitro. 2018;48:33-44 pubmed publisher
Li Z, Liu F, Zhang L, Cao Y, Shao Y, Wang X, et al. Neuroserpin restores autophagy and promotes functional recovery after acute spinal cord injury in rats. Mol Med Rep. 2018;17:2957-2963 pubmed publisher
Sciacca G, Cicchetti F. Mutant huntingtin protein expression and blood-spinal cord barrier dysfunction in huntington disease. Ann Neurol. 2017;82:981-994 pubmed publisher
Liu J, Wang L, Du Y, Liu S. An Important Function of Petrosiol E in Inducing the Differentiation of Neuronal Progenitors and in Protecting Them against Oxidative Stress. Adv Sci (Weinh). 2017;4:1700089 pubmed publisher
Yuan C, Xu M, Rong R, Mei Y, Cai W, Li L, et al. miR-200c regulates endothelin-1 induced PASMCs abnormal proliferation and apoptosis. IUBMB Life. 2017;69:877-886 pubmed publisher
Zong X, Wu S, Li F, Lv L, Han D, Zhao N, et al. Transplantation of VEGF-mediated bone marrow mesenchymal stem cells promotes functional improvement in a rat acute cerebral infarction model. Brain Res. 2017;1676:9-18 pubmed publisher
Chen L, Ning H, Yin Z, Song X, Feng Y, Qin H, et al. The effects of fluoride on neuronal function occurs via cytoskeleton damage and decreased signal transmission. Chemosphere. 2017;185:589-594 pubmed publisher
Zhang X, Lin Y, Eschmann N, Zhou H, Rauch J, Hernandez I, et al. RNA stores tau reversibly in complex coacervates. PLoS Biol. 2017;15:e2002183 pubmed publisher
Zeng W, Jiang H, Gang Y, Song Y, Shen Z, Yang H, et al. Anterograde monosynaptic transneuronal tracers derived from herpes simplex virus 1 strain H129. Mol Neurodegener. 2017;12:38 pubmed publisher
Wang C, Sun C, Hu Z, Huo X, Yang Y, Liu X, et al. Improved Neural Regeneration with Olfactory Ensheathing Cell Inoculated PLGA Scaffolds in Spinal Cord Injury Adult Rats. Neurosignals. 2017;25:1-14 pubmed publisher
Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi L, et al. Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell. 2017;20:397-406.e5 pubmed publisher
Andharia N, Joseph A, Hayashi M, Okada M, Matsuda H. Involvement of intracellular transport in TREK-1c current run-up in 293T cells. Channels (Austin). 2017;11:224-235 pubmed publisher
Kim H, Wegner S, Van Ness K, Park J, Pacheco S, Workman T, et al. Differential epigenetic effects of chlorpyrifos and arsenic in proliferating and differentiating human neural progenitor cells. Reprod Toxicol. 2016;65:212-223 pubmed publisher
Jeon I, Cicchetti F, Cisbani G, Lee S, Li E, Bae J, et al. Human-to-mouse prion-like propagation of mutant huntingtin protein. Acta Neuropathol. 2016;132:577-92 pubmed publisher
Zhang X, Tang S, Zhang Q, Shao W, Han X, Wang Y, et al. Endoplasmic reticulum stress mediates JNK-dependent IRS-1 serine phosphorylation and results in Tau hyperphosphorylation in amyloid ? oligomer-treated PC12 cells and primary neurons. Gene. 2016;587:183-93 pubmed publisher
Huang J, Ma Y, Yuan Y, Zuo W, Chu S, Liu H, et al. Claulansine F promoted the neuronal differentiation of neural stem and progenitor cells through Akt/GSK-3?/?-catenin pathway. Eur J Pharmacol. 2016;786:72-84 pubmed publisher
He G, Xu W, Tong L, Li S, Su S, Tan X, et al. Gadd45b prevents autophagy and apoptosis against rat cerebral neuron oxygen-glucose deprivation/reperfusion injury. Apoptosis. 2016;21:390-403 pubmed publisher
He G, Xu W, Li J, Li S, Liu B, Tan X, et al. Huwe1 interacts with Gadd45b under oxygen-glucose deprivation and reperfusion injury in primary Rat cortical neuronal cells. Mol Brain. 2015;8:88 pubmed publisher
Yu H, Sun D, Wang N, Wang M, Lan Y, Fan W, et al. Headless Myo10 is a regulator of microtubule stability during neuronal development. J Neurochem. 2015;135:261-73 pubmed publisher
Li F, Wang Y, Yu L, Cao S, Wang K, Yuan J, et al. Viral Infection of the Central Nervous System and Neuroinflammation Precede Blood-Brain Barrier Disruption during Japanese Encephalitis Virus Infection. J Virol. 2015;89:5602-14 pubmed publisher
Zhang L, Feng D, Tao H, DE X, Chang Q, Hu Q. Increased stathmin expression strengthens fear conditioning in epileptic rats. Biomed Rep. 2015;3:28-32 pubmed
product information
CatalogNo :
17490-1-AP
AntigenName :
MAP2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
microtubule-associated protein 2
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
MAP 2, MAP2, MAP2A, MAP2B, MAP2C
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC038857
Category :
Apoptosis;Binding Proteins;Cytoskeleton/Scaffold Proteins;Disease Related;Neurology;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:100 ; IHC 1:100 ; IP 1:1000 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.