This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TIMP-2
catalog :
17353-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry
citations: 17
Reference
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, et al. Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway. Biomed Res Int. 2020;2020:3126182 pubmed publisher
Ou Y, Zhu L, Wei X, Bai S, Chen M, Chen H, et al. Circular RNA circ_0111277 attenuates human trophoblast cell invasion and migration by regulating miR-494/HTRA1/Notch-1 signal pathway in pre-eclampsia. Cell Death Dis. 2020;11:479 pubmed publisher
Sun L, Qu L, Brigstock D, Li H, Li Y, Gao R. Biological and Proteomic Characteristics of an Immortalized Human Pancreatic Stellate Cell Line. Int J Med Sci. 2020;17:137-144 pubmed publisher
Chen I, Luo H, Su Y, Huang C, Chiang P, Yu C, et al. Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway. Molecules. 2019;24: pubmed publisher
Cecen B, Keles D, Oktay G, Kozaci L. Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells. Chem Biol Interact. 2019;310:108730 pubmed publisher
Wu J, Yang J, Lu X, Jin C, Wu S, Zhang L, et al. Lanthanum Chloride Impairs the Blood-Brain Barrier Integrity by Reduction of Junctional Proteins and Upregulation of MMP-9 in Rats. Biol Trace Elem Res. 2019;187:482-491 pubmed publisher
Tian Y, Chen K, Zulkefli N, Maner R, Hsieh C. Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. Molecules. 2018;23: pubmed publisher
He X, Shi L, Qiu M, Li Q, Wang M, Xiong Z, et al. Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families. Biochem Biophys Res Commun. 2018;504:878-884 pubmed publisher
Liu L, Li Y, Wang Z, Ding F, Cheng Z, Xu Q, et al. Rab7 empowers renal tubular epithelial cells with autophagy-mediated protection against albumin-induced injury. Exp Cell Res. 2018;370:198-207 pubmed publisher
Xue X, Wang X, Zhao Y, Hu R, Qin L. Exosomal miR-93 promotes proliferation and invasion in hepatocellular carcinoma by directly inhibiting TIMP2/TP53INP1/CDKN1A. Biochem Biophys Res Commun. 2018;502:515-521 pubmed publisher
Geng J, Yu X, Liu C, Sun C, Guo M, Li Z, et al. Herba Artemisiae Capillaris Extract Prevents the Development of Streptozotocin-Induced Diabetic Nephropathy of Rat. Evid Based Complement Alternat Med. 2018;2018:5180165 pubmed publisher
Zhang J, Yang A, Wu Y, Guan W, Xiong B, Peng X, et al. Stachydrine ameliorates carbon tetrachloride-induced hepatic fibrosis by inhibiting inflammation, oxidative stress and regulating MMPs/TIMPs system in rats. Biomed Pharmacother. 2018;97:1586-1594 pubmed publisher
Zhang M, Hu X, Li S, Lu C, Li J, Zong Y, et al. Hepatoprotective effects of ethyl pyruvate against CCl4-induced hepatic fibrosis via inhibition of TLR4/NF-κB signaling and up-regulation of MMPs/TIMPs ratio. Clin Res Hepatol Gastroenterol. 2018;42:72-81 pubmed publisher
Neoh C, Wu W, Dai G, Su J, Liu C, Su T, et al. Flaccidoxide-13-Acetate Extracted from the Soft Coral Cladiella kashmani Reduces Human Bladder Cancer Cell Migration and Invasion through Reducing Activation of the FAK/PI3K/AKT/mTOR Signaling Pathway. Molecules. 2017;23: pubmed publisher
Cheng T, Din Z, Su J, Wu Y, Liu C. Sinulariolide Suppresses Cell Migration and Invasion by Inhibiting Matrix Metalloproteinase-2/-9 and Urokinase through the PI3K/AKT/mTOR Signaling Pathway in Human Bladder Cancer Cells. Mar Drugs. 2017;15: pubmed publisher
Zhu M, Zhang N, He S, Yan R, Zhang J. MicroRNA-106a functions as an oncogene in human gastric cancer and contributes to proliferation and metastasis in vitro and in vivo. Clin Exp Metastasis. 2016;33:509-19 pubmed publisher
Xie Y, Cui D, Sui L, Xu Y, Zhang N, Ma Y, et al. Induction of forkhead box M1 (FoxM1) by EGF through ERK signaling pathway promotes trophoblast cell invasion. Cell Tissue Res. 2015;362:421-30 pubmed publisher
product information
CatalogNo :
17353-1-AP
AntigenName :
TIMP-2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
TIMP metallopeptidase inhibitor 2
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CSC 21K, Metalloproteinase inhibitor 2, TIMP 2, TIMP2, TIMP-2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC052605
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:200 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.