This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
RB1CC1
catalog :
17250-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 40
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 2d
Chino H, Hatta T, Natsume T, Mizushima N. Intrinsically Disordered Protein TEX264 Mediates ER-phagy. Mol Cell. 2019;74:909-921.e6 pubmed publisher
  • western blot; human; loading ...; fig s6e
Huang X, Gan G, Wang X, Xu T, Xie W. The HGF-MET axis coordinates liver cancer metabolism and autophagy for chemotherapeutic resistance. Autophagy. 2019;15:1258-1279 pubmed publisher
  • western blot; human; loading ...; fig 9f
Jung J, Nayak A, Schaeffer V, Starzetz T, Kirsch A, Muller S, et al. Multiplex image-based autophagy RNAi screening identifies SMCR8 as ULK1 kinase activity and gene expression regulator. elife. 2017;6: pubmed publisher
Xia H, Li S, Li X, Wang W, Bian Y, Wei S, et al. Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis. JCI Insight. 2020;: pubmed publisher
Chu Y, Kang Y, Yan C, Yang C, Zhang T, Huo H, et al. LUBAC and OTULIN regulate autophagy initiation and maturation by mediating the linear ubiquitination and the stabilization of ATG13. Autophagy. 2020;:1-16 pubmed publisher
You M, Miao Z, Sienkiewicz O, Jiang X, Zhao X, Hu F. 10-Hydroxydecanoic acid inhibits LPS-induced inflammation by targeting p53 in microglial cells. Int Immunopharmacol. 2020;84:106501 pubmed publisher
Nozawa T, Sano S, Minowa Nozawa A, Toh H, Nakajima S, Murase K, et al. TBC1D9 regulates TBK1 activation through Ca2+ signaling in selective autophagy. Nat Commun. 2020;11:770 pubmed publisher
Li G, Song Y, Liao Z, Wang K, Luo R, Lu S, et al. Bone-derived mesenchymal stem cells alleviate compression-induced apoptosis of nucleus pulposus cells by N6 methyladenosine of autophagy. Cell Death Dis. 2020;11:103 pubmed publisher
Leidal A, Huang H, Marsh T, Solvik T, Zhang D, Ye J, et al. The LC3-conjugation machinery specifies the loading of RNA-binding proteins into extracellular vesicles. Nat Cell Biol. 2020;22:187-199 pubmed publisher
Wible D, Chao H, Tang D, Bratton S. ATG5 cancer mutations and alternative mRNA splicing reveal a conjugation switch that regulates ATG12-ATG5-ATG16L1 complex assembly and autophagy. Cell Discov. 2019;5:42 pubmed publisher
Thomas N, Choi H, Wei X, Wang L, Mishina Y, Guan J, et al. Autophagy Regulates Craniofacial Bone Acquisition. Calcif Tissue Int. 2019;: pubmed publisher
Zachari M, Gudmundsson S, Li Z, Manifava M, Shah R, Smith M, et al. Selective Autophagy of Mitochondria on a Ubiquitin-Endoplasmic-Reticulum Platform. Dev Cell. 2019;50:627-643.e5 pubmed publisher
Yuan F, Jin X, Li D, Song Y, Zhang N, Yang X, et al. ULK1 phosphorylates Mad1 to regulate spindle assembly checkpoint. Nucleic Acids Res. 2019;47:8096-8110 pubmed publisher
Tamura N, Kageyama S, Komatsu M, Waguri S. Hyperosmotic stress induces unconventional autophagy independent of the Ulk1 complex. Mol Cell Biol. 2019;: pubmed publisher
Fujimaki M, Furuya N, Saiki S, Amo T, Imamichi Y, Hattori N. Iron supply via NCOA4-mediated ferritin degradation maintains mitochondrial functions. Mol Cell Biol. 2019;: pubmed publisher
Vargas J, Wang C, Bunker E, Hao L, Maric D, Schiavo G, et al. Spatiotemporal Control of ULK1 Activation by NDP52 and TBK1 during Selective Autophagy. Mol Cell. 2019;74:347-362.e6 pubmed publisher
Kumar S, Gu Y, Abudu Y, Bruun J, Jain A, Farzam F, et al. Phosphorylation of Syntaxin 17 by TBK1 Controls Autophagy Initiation. Dev Cell. 2019;: pubmed publisher
Lan Y, Sullivan P, Hu F. SMCR8 negatively regulates AKT and MTORC1 signaling to modulate lysosome biogenesis and tissue homeostasis. Autophagy. 2019;15:871-885 pubmed publisher
Ho W, Tai Y, Chang J, Liang J, Tyan S, Chen S, et al. The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy. Autophagy. 2019;15:827-842 pubmed publisher
Li L, Wang G, Hu J, Zhang G, Chen H, Yuan Y, et al. RB1CC1-enhanced autophagy facilitates PSCs activation and pancreatic fibrogenesis in chronic pancreatitis. Cell Death Dis. 2018;9:952 pubmed publisher
Wang C, Wang H, Zhang D, Luo W, Liu R, Xu D, et al. Phosphorylation of ULK1 affects autophagosome fusion and links chaperone-mediated autophagy to macroautophagy. Nat Commun. 2018;9:3492 pubmed publisher
Morita K, Hama Y, Izume T, Tamura N, Ueno T, Yamashita Y, et al. Genome-wide CRISPR screen identifies TMEM41B as a gene required for autophagosome formation. J Cell Biol. 2018;217:3817-3828 pubmed publisher
Matsui T, Jiang P, Nakano S, Sakamaki Y, Yamamoto H, Mizushima N. Autophagosomal YKT6 is required for fusion with lysosomes independently of syntaxin 17. J Cell Biol. 2018;217:2633-2645 pubmed publisher
Zhao Y, Liu N, Miao G, Chen Y, Zhao H, Zhang H. The ER Contact Proteins VAPA/B Interact with Multiple Autophagy Proteins to Modulate Autophagosome Biogenesis. Curr Biol. 2018;28:1234-1245.e4 pubmed publisher
Guo M, Mu Y, Yu D, Li J, Chen F, Wei B, et al. Comparison of the expression of TGF-β1, E-cadherin, N-cadherin, TP53, RB1CC1 and HIF-1α in oral squamous cell carcinoma and lymph node metastases of humans and mice. Oncol Lett. 2018;15:1639-1645 pubmed publisher
Falcon B, Noad J, McMahon H, Randow F, Goedert M. Galectin-8-mediated selective autophagy protects against seeded tau aggregation. J Biol Chem. 2018;293:2438-2451 pubmed publisher
Wallot Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. 2018;14:743-763 pubmed publisher
Tamura N, Nishimura T, Sakamaki Y, Koyama Honda I, Yamamoto H, Mizushima N. Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets. FEBS Lett. 2017;591:3819-3830 pubmed publisher
Muniz Feliciano L, Doggett T, Zhou Z, Ferguson T. RUBCN/rubicon and EGFR regulate lysosomal degradative processes in the retinal pigment epithelium (RPE) of the eye. Autophagy. 2017;13:2072-2085 pubmed publisher
Ge L, Zhang M, Kenny S, Liu D, Maeda M, Saito K, et al. Remodeling of ER-exit sites initiates a membrane supply pathway for autophagosome biogenesis. EMBO Rep. 2017;18:1586-1603 pubmed publisher
Sasai M, Sakaguchi N, Ma J, Nakamura S, Kawabata T, Bando H, et al. Essential role for GABARAP autophagy proteins in interferon-inducible GTPase-mediated host defense. Nat Immunol. 2017;18:899-910 pubmed publisher
Nishimura T, Tamura N, Kono N, Shimanaka Y, Arai H, Yamamoto H, et al. Autophagosome formation is initiated at phosphatidylinositol synthase-enriched ER subdomains. EMBO J. 2017;36:1719-1735 pubmed publisher
Pandey A, Ding S, Qin Q, Gupta R, Gomez G, Lin F, et al. Global Reprogramming of Host Kinase Signaling in Response to Fungal Infection. Cell Host Microbe. 2017;21:637-649.e6 pubmed publisher
Chen X, Clark J, Wunderlich M, Fan C, Davis A, Chen S, et al. Autophagy is dispensable for Kmt2a/Mll-Mllt3/Af9 AML maintenance and anti-leukemic effect of chloroquine. Autophagy. 2017;13:955-966 pubmed publisher
Sullivan P, Zhou X, Robins A, Paushter D, Kim D, Smolka M, et al. The ALS/FTLD associated protein C9orf72 associates with SMCR8 and WDR41 to regulate the autophagy-lysosome pathway. Acta Neuropathol Commun. 2016;4:51 pubmed publisher
Chen S, Wang C, Yeo S, Liang C, Okamoto T, Sun S, et al. Distinct roles of autophagy-dependent and -independent functions of FIP200 revealed by generation and analysis of a mutant knock-in mouse model. Genes Dev. 2016;30:856-69 pubmed publisher
Wang C, Chen S, Yeo S, Karsli Uzunbas G, White E, Mizushima N, et al. Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide. J Cell Biol. 2016;212:545-60 pubmed publisher
Guo X, Xue H, Guo X, Gao X, Xu S, Yan S, et al. MiR224-3p inhibits hypoxia-induced autophagy by targeting autophagy-related genes in human glioblastoma cells. Oncotarget. 2015;6:41620-37 pubmed publisher
Yao J, Jia L, Khan N, Lin C, Mitter S, Boulton M, et al. Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium. Autophagy. 2015;11:939-53 pubmed publisher
Seglen P, Luhr M, Mills I, Sætre F, Szalai P, Engedal N. Macroautophagic cargo sequestration assays. Methods. 2015;75:25-36 pubmed publisher
product information
CatalogNo :
17250-1-AP
AntigenName :
RB1CC1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
RB1-inducible coiled-coil 1
Immunogen :
Fusion Protein
Species :
human, monkey, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, co-IP, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CC1, DRAGOU14, FIP200, KIAA0203, RB1 inducible coiled coil 1, RB1CC1, RBICC
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC017556
Category :
Apoptosis;Autophagy;Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:50 ; IP 1:500 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.