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product summary
company name :
Proteintech Group
product type :
antibody
product name :
Histone-H3
catalog :
17168-1-AP
quantity :
150UL
price :
99 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, flow cytometry
citations: 209
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 5, 6e
Ju L, Shan L, Yin B, Song Y. δ-Catenin regulates proliferation and apoptosis in renal cell carcinoma via promoting β-catenin nuclear localization and activating its downstream target genes. Cancer Med. 2020;9:2201-2212 pubmed publisher
  • western blot; mouse; 1:3000; fig 13c
Xu B, Lang L, Li S, Guo J, Wang J, Yang H, et al. Microglia Activated by Excess Cortisol Induce HMGB1 Acetylation and Neuroinflammation in the Hippocampal DG Region of Mice Following Cold Exposure. Biomolecules. 2019;9: pubmed publisher
  • western blot; human; loading ...; fig 5b
Yan Y, Zhao W, Huang Y, Tong H, Xia Y, Jiang Q, et al. Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells. Sci Rep. 2017;7:46276 pubmed publisher
  • western blot; human; fig 5
Chen Y, Pan K, Wang P, Cao Z, Wang W, Wang S, et al. HBP1-mediated Regulation of p21 Protein through the Mdm2/p53 and TCF4/EZH2 Pathways and Its Impact on Cell Senescence and Tumorigenesis. J Biol Chem. 2016;291:12688-705 pubmed publisher
  • western blot; human; loading ...; fig 3e
Zhang P, Li G, Deng Z, Liu L, Chen L, Tang J, et al. Dicer interacts with SIRT7 and regulates H3K18 deacetylation in response to DNA damaging agents. Nucleic Acids Res. 2016;44:3629-42 pubmed publisher
  • western blot; mouse; fig 2
Gao Q, Liu Y, Wu Y, Zhao Q, Wang L, Gao S, et al. IL-17 intensifies IFN-γ-induced NOS2 upregulation in RAW 264.7 cells by further activating STAT1 and NF-κB. Int J Mol Med. 2016;37:347-58 pubmed publisher
Sun B, Wang X, Liu X, Wang L, Ren F, Wang X, et al. Hippuric Acid Promotes Renal Fibrosis by Disrupting Redox Homeostasis via Facilitation of NRF2-KEAP1-CUL3 Interactions in Chronic Kidney Disease. Antioxidants (Basel). 2020;9: pubmed publisher
Jia Z, Zhang Y, Yan A, Wang M, Han Q, Wang K, et al. 1,25-dihydroxyvitamin D3 signaling-induced decreases in IRX4 inhibits NANOG-mediated cancer stem-like properties and gefitinib resistance in NSCLC cells. Cell Death Dis. 2020;11:670 pubmed publisher
Zhang Y, Zhao S, Fu Y, Yan L, Feng Y, Chen Y, et al. Computational repositioning of dimethyl fumarate for treating alcoholic liver disease. Cell Death Dis. 2020;11:641 pubmed publisher
Zhou K, Zheng Z, Li Y, Han W, Zhang J, Mao Y, et al. TFE3, a potential therapeutic target for Spinal Cord Injury via augmenting autophagy flux and alleviating ER stress. Theranostics. 2020;10:9280-9302 pubmed publisher
Li Y, Xia L, Tan K, Ye X, Zuo Z, Li M, et al. N6-Methyladenosine co-transcriptionally directs the demethylation of histone H3K9me2. Nat Genet. 2020;52:870-877 pubmed publisher
Yang H, Chen Y, Jiang Y, Wang D, Yan J, Zhou Z. TP53 mutation influences the efficacy of treatment of colorectal cancer cell lines with a combination of sirtuin inhibitors and chemotherapeutic agents. Exp Ther Med. 2020;20:1415-1422 pubmed publisher
Feng Q, Bian X, Liu X, Wang Y, Zhou H, Ma X, et al. Intracellular expression of arginine deiminase activates the mitochondrial apoptosis pathway by inhibiting cytosolic ferritin and inducing chromatin autophagy. BMC Cancer. 2020;20:665 pubmed publisher
Zhang X, Ye P, Huang H, Wang B, Dong F, Ling Q. TCF7L2 rs290487 C allele aberrantly enhances hepatic gluconeogenesis through allele-specific changes in transcription and chromatin binding. Aging (Albany NY). 2020;12:13365-13387 pubmed publisher
Liu D, Zhang H, Cui M, Chen C, Feng Y. Hsa-miR-425-5p promotes tumor growth and metastasis by activating the CTNND1-mediated β-catenin pathway and EMT in colorectal cancer. Cell Cycle. 2020;19:1917-1927 pubmed publisher
Jin Y, Liu J, Liu Y, Liu Y, Guo G, Yu S, et al. Oxymatrine Inhibits Renal Cell Carcinoma Progression by Suppressing β-Catenin Expression. Front Pharmacol. 2020;11:808 pubmed publisher
Peng S, Sun Y, Luo Y, Ma S, Sun W, Tang G, et al. MFP-FePt-GO Nanocomposites Promote Radiosensitivity of Non-Small Cell Lung Cancer Via Activating Mitochondrial-Mediated Apoptosis and Impairing DNA Damage Repair. Int J Biol Sci. 2020;16:2145-2158 pubmed publisher
Wang Y, Li C, Li J, Wang G, Li L. Non-Esterified Fatty Acid-Induced Reactive Oxygen Species Mediated Granulosa Cells Apoptosis Is Regulated by Nrf2/p53 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Gan P, Ding L, Hang G, Xia Q, Huang Z, Ye X, et al. Oxymatrine Attenuates Dopaminergic Neuronal Damage and Microglia-Mediated Neuroinflammation Through Cathepsin D-Dependent HMGB1/TLR4/NF-κB Pathway in Parkinson's Disease. Front Pharmacol. 2020;11:776 pubmed publisher
Dong X, Wu D, Zhang Y, Jia L, Pan X, Sun J, et al. Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Zhou Q, Huang J, Zhang C, Zhao F, Kim W, Tu X, et al. The bromodomain containing protein BRD-9 orchestrates RAD51-RAD54 complex formation and regulates homologous recombination-mediated repair. Nat Commun. 2020;11:2639 pubmed publisher
Zhan W, Liao X, Liu J, Tian T, Yu L, Li R. USP38 regulates the stemness and chemoresistance of human colorectal cancer via regulation of HDAC3. Oncogenesis. 2020;9:48 pubmed publisher
Wang L, Ai M, Nie M, Zhao L, Deng G, Hu S, et al. EHF promotes colorectal carcinoma progression by activating TGF-β1 transcription and canonical TGF-β signaling. Cancer Sci. 2020;111:2310-2324 pubmed publisher
Liu H, Chen C, Ma D, Li Y, Yin Q, Li Q, et al. Inhibition of PIM1 attenuates the stem cell-like traits of breast cancer cells by promoting RUNX3 nuclear retention. J Cell Mol Med. 2020;24:6308-6323 pubmed publisher
Wu Y, Chen J, Sun Y, Dong X, Wang Z, Chen J, et al. PGN and LTA from Staphylococcus aureus Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells. Toxins (Basel). 2020;12: pubmed publisher
Yang F, Li S, Cheng Y, Li J, Han X. Karyopherin α 2 promotes proliferation, migration and invasion through activating NF-κB/p65 signaling pathways in melanoma cells. Life Sci. 2020;252:117611 pubmed publisher
Wang Y, Chen J, Li S, Zhang X, Guo Z, Hu J, et al. Exogenous spermine attenuates rat diabetic cardiomyopathy via suppressing ROS-p53 mediated downregulation of calcium-sensitive receptor. Redox Biol. 2020;32:101514 pubmed publisher
Shen L, Yang S, Yang F, Guan D, He S. CaCBL1 Acts as a Positive Regulator in Pepper Response to Ralstonia solanacearum. Mol Plant Microbe Interact. 2020;33:945-957 pubmed publisher
Jin Z, Zhu Z, Liu S, Hou Y, Tang M, Zhu P, et al. TRIM59 Protects Mice From Sepsis by Regulating Inflammation and Phagocytosis in Macrophages. Front Immunol. 2020;11:263 pubmed publisher
Wang M, Wang H, Tao Z, Xia Q, Hao Z, Prehn J, et al. C9orf72 associates with inactive Rag GTPases and regulates mTORC1-mediated autophagosomal and lysosomal biogenesis. Aging Cell. 2020;19:e13126 pubmed publisher
Ji X, Liu T, Zhao S, Li J, Li L, Wang E. WISP-2, an upregulated gene in hip cartilage from the DDH model rats, induces chondrocyte apoptosis through PPARγ in vitro. FASEB J. 2020;34:4904-4917 pubmed publisher
Qi L, Jiang J, Zhang J, Zhang L, Wang T. Curcumin Protects Human Trophoblast HTR8/SVneo Cells from H2O2-Induced Oxidative Stress by Activating Nrf2 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Majumder M, PALANISAMY V. RNA binding protein FXR1-miR301a-3p axis contributes to p21WAF1 degradation in oral cancer. PLoS Genet. 2020;16:e1008580 pubmed publisher
Chen G, Lv W, Xu Y, Wei X, Xu Y, Luo Z. Functional analysis of MTF-1 and MT promoters and their transcriptional response to zinc (Zn) and copper (Cu) in yellow catfish Pelteobagrus fulvidraco. Chemosphere. 2020;246:125792 pubmed publisher
Chen Y, Wu J, Liang G, Geng G, Zhao F, Yin P, et al. CHK2-FOXK axis promotes transcriptional control of autophagy programs. Sci Adv. 2020;6:eaax5819 pubmed publisher
Li S, Li Q, Zhu Y, Hu W. GDF15 induced by compressive force contributes to osteoclast differentiation in human periodontal ligament cells. Exp Cell Res. 2020;387:111745 pubmed publisher
Xue M, Liang H, Ji X, Liu Y, Ge Y, Hou L, et al. Fucoidan prevent murine autoimmune diabetes via suppression TLR4-signaling pathways, regulation DC/Treg induced immune tolerance and improving gut microecology. Nutr Metab (Lond). 2019;16:87 pubmed publisher
Yang L, Lei Q, Li L, Yang J, Dong Z, Cui H. Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer. Clin Epigenetics. 2019;11:199 pubmed publisher
Wang K, Wei H, Zhan J, Liang X, Zhang C, Liu Y, et al. GSPE alleviates renal fibrosis by inhibiting the activation of C3/ HMGB1/ TGF-β1 pathway. Chem Biol Interact. 2019;316:108926 pubmed publisher
Huang X, Ni B, Xi Y, Chu X, Zhang R, You H. Protease-activated receptor 2 (PAR-2) antagonist AZ3451 as a novel therapeutic agent for osteoarthritis. Aging (Albany NY). 2019;11:12532-12545 pubmed publisher
Li K, Zhang J, Tian Y, He Y, Xu X, Pan W, et al. The Wnt/β-catenin/VASP positive feedback loop drives cell proliferation and migration in breast cancer. Oncogene. 2019;: pubmed publisher
Wang H, Wang N, Xu D, Ma Q, Chen Y, Xu S, et al. Oxidation of multiple MiT/TFE transcription factors links oxidative stress to transcriptional control of autophagy and lysosome biogenesis. Autophagy. 2019;:1-14 pubmed publisher
Luo Y, Yang P, Li Z, Luo Y, Shen J, Li R, et al. Liraglutide Improves Non-Alcoholic Fatty Liver Disease In Diabetic Mice By Modulating Inflammatory Signaling Pathways. Drug Des Devel Ther. 2019;13:4065-4074 pubmed publisher
Zhu M, Yu X, Zheng Z, Huang J, Yang X, Shi H. Capsaicin suppressed activity of prostate cancer stem cells by inhibition of Wnt/β-catenin pathway. Phytother Res. 2019;: pubmed publisher
Kim W, Zhao F, Wu R, Qin S, Nowsheen S, Huang J, et al. ZFP161 regulates replication fork stability and maintenance of genomic stability by recruiting the ATR/ATRIP complex. Nat Commun. 2019;10:5304 pubmed publisher
Zhou K, Chen H, Lin J, Xu H, Wu H, Bao G, et al. FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival. Cell Death Dis. 2019;10:872 pubmed publisher
Gao P, Chai Y, Song J, Liu T, Chen P, Zhou L, et al. Reprogramming the unfolded protein response for replication by porcine reproductive and respiratory syndrome virus. PLoS Pathog. 2019;15:e1008169 pubmed publisher
Jia L, Xiong Y, Zhang W, Ma X, Xu X. Metformin promotes osteogenic differentiation and protects against oxidative stress-induced damage in periodontal ligament stem cells via activation of the Akt/Nrf2 signaling pathway. Exp Cell Res. 2019;:111717 pubmed publisher
Sun J, Piao J, Li N, Yang Y, Kim K, Lin Z. Valproic acid targets HDAC1/2 and HDAC1/PTEN/Akt signalling to inhibit cell proliferation via the induction of autophagy in gastric cancer. FEBS J. 2019;: pubmed publisher
Fei Y, Chaulagain A, Wang T, Chen Y, Liu J, Yi M, et al. MiR-146a down-regulates inflammatory response by targeting TLR3 and TRAF6 in Coxsackievirus B infection. RNA. 2019;: pubmed publisher
Huang S, Wang L, Xue N, Li C, Guo H, Ren T, et al. Chlorogenic acid effectively treats cancers through induction of cancer cell differentiation. Theranostics. 2019;9:6745-6763 pubmed publisher
Qi Y, Wang D, Huang W, Wang B, Huang D, Xiong F, et al. CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma. J Exp Clin Cancer Res. 2019;38:413 pubmed publisher
Xing J, Li J, Fu L, Gai J, Guan J, Li Q. SIRT4 enhances the sensitivity of ER-positive breast cancer to tamoxifen by inhibiting the IL-6/STAT3 signal pathway. Cancer Med. 2019;8:7086-7097 pubmed publisher
Cao P, Wang Y, Lv Y, Jiang N, Zhong L, Ma X, et al. PI3K p110α inhibition sensitizes cervical cancer cells with aberrant PI3K signaling activation to PARP inhibitor BMN673. Oncol Rep. 2019;42:2097-2107 pubmed publisher
Li X, Han Z, Liu Y, Hong L, Cui B, Cui X. Endogenous ET-1 promotes ANP secretion through activation of COX2-L-PGDS-PPARγ signaling in hypoxic beating rat atria. Peptides. 2019;122:170150 pubmed publisher
Wang S, Ai H, Liu L, Zhang X, Gao F, Zheng L, et al. Micro-RNA-27a/b negatively regulates hepatic gluconeogenesis by targeting FOXO1. Am J Physiol Endocrinol Metab. 2019;317:E911-E924 pubmed publisher
Fu L, Peng S, Wu W, Ouyang Y, Tan D, Fu X. LncRNA HOTAIRM1 promotes osteogenesis by controlling JNK/AP-1 signalling-mediated RUNX2 expression. J Cell Mol Med. 2019;23:7517-7524 pubmed publisher
Zhang H, Ji L, Yang Y, Wei Y, Zhang X, Gang Y, et al. The Therapeutic Effects of Treadmill Exercise on Osteoarthritis in Rats by Inhibiting the HDAC3/NF-KappaB Pathway in vivo and in vitro. Front Physiol. 2019;10:1060 pubmed publisher
Miao Y, Shen Q, Zhang S, Huang H, Meng X, Zheng X, et al. Calcium-sensing stromal interaction molecule 2 upregulates nuclear factor of activated T cells 1 and transforming growth factor-β signaling to promote breast cancer metastasis. Breast Cancer Res. 2019;21:99 pubmed publisher
Jiang Y, Liu F, Zou F, Zhang Y, Wang B, Zhang Y, et al. PBX homeobox 1 enhances hair follicle mesenchymal stem cell proliferation and reprogramming through activation of the AKT/glycogen synthase kinase signaling pathway and suppression of apoptosis. Stem Cell Res Ther. 2019;10:268 pubmed publisher
Li S, Jiang W, Xiao W, Li K, Zhang Y, Guo X, et al. KMT2D deficiency enhances the anti-cancer activity of L48H37 in pancreatic ductal adenocarcinoma. World J Gastrointest Oncol. 2019;11:599-621 pubmed publisher
Wang Y, Yang C, Elsheikh N, Li C, YANG F, Wang G, et al. HO-1 reduces heat stress-induced apoptosis in bovine granulosa cells by suppressing oxidative stress. Aging (Albany NY). 2019;11:5535-5547 pubmed publisher
He R, Wang M, Zhao C, Shen M, Yu Y, He L, et al. TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. J Exp Clin Cancer Res. 2019;38:340 pubmed publisher
Zhang C, Duan Y, Xia M, Dong Y, Chen Y, Zheng L, et al. TFEB mediates immune evasion and resistance to mTOR inhibition of renal cell carcinoma via induction of PD-L1. Clin Cancer Res. 2019;: pubmed publisher
Sun L, Qiao W, Xiao Y, Cui L, Wang X, Ren W. Naringin mitigates myocardial strain and the inflammatory response in sepsis-induced myocardial dysfunction through regulation of PI3K/AKT/NF-κB pathway. Int Immunopharmacol. 2019;75:105782 pubmed publisher
Zhao Y, Deng H, Li K, Wang L, Wu Y, Dong X, et al. Trans-cinnamaldehyde improves neuroinflammation-mediated NMDA receptor dysfunction and memory deficits through blocking NF-κB pathway in presenilin1/2 conditional double knockout mice. Brain Behav Immun. 2019;: pubmed publisher
Gao J, Wang J, Wang X. MD-2 Homologue Recognizes the White Spot Syndrome Virus Lipid Component and Induces Antiviral Molecule Expression in Shrimp. J Immunol. 2019;203:1131-1141 pubmed publisher
Sirri V, Grob A, Berthelet J, Jourdan N, Roussel P. Sirtuin 7 promotes 45S pre-rRNA cleavage at site 2 and determines the processing pathway. J Cell Sci. 2019;132: pubmed publisher
Xu J, Sheng Z, Li F, Wang S, Yuan Y, Wang M, et al. NEDD4 protects vascular endothelial cells against Angiotensin II-induced cell death via enhancement of XPO1-mediated nuclear export. Exp Cell Res. 2019;:111505 pubmed publisher
Ge L, Yan L, Li C, Cheng K. Bavachinin exhibits antitumor activity against non‑small cell lung cancer by targeting PPARγ. Mol Med Rep. 2019;20:2805-2811 pubmed publisher
Song G, Zhang Y, Yu S, Lv W, Guan Z, Sun M, et al. Chrysophanol attenuates airway inflammation and remodeling through nuclear factor-kappa B signaling pathway in asthma. Phytother Res. 2019;: pubmed publisher
Sun L, Li Z, Xue H, Ma T, Ren C, Li M, et al. MiR-26a promotes fracture healing of nonunion rats possibly by targeting SOSTDC1 and further activating Wnt/β-catenin signaling pathway. Mol Cell Biochem. 2019;: pubmed publisher
Wang Y, Ai L, Hai B, Cao Y, Li R, Li H, et al. Tempol alleviates chronic intermittent hypoxia-induced pancreatic injury through repressing inflammation and apoptosis. Physiol Res. 2019;68:445-455 pubmed
Fish L, Navickas A, Culbertson B, Xu Y, Nguyen H, Zhang S, et al. Nuclear TARBP2 Drives Oncogenic Dysregulation of RNA Splicing and Decay. Mol Cell. 2019;75:967-981.e9 pubmed publisher
Lu M, Zhao J, Liu Y, Liu T, Tao M, You Q, et al. CPUY192018, a potent inhibitor of the Keap1-Nrf2 protein-protein interaction, alleviates renal inflammation in mice by restricting oxidative stress and NF-κB activation. Redox Biol. 2019;26:101266 pubmed publisher
Zhao K, Li Y, Wang Z, Han N, Wang Y. Carnosine Protects Mouse Podocytes from High Glucose Induced Apoptosis through PI3K/AKT and Nrf2 Pathways. Biomed Res Int. 2019;2019:4348973 pubmed publisher
Zhang M, Cao X, Xu F, Liang X, Fu L, Li B, et al. In human sperm nucleus nucleosomes form spatially restricted domains consistent with programmed nucleosome positioning. Biol Open. 2019;: pubmed publisher
Li Y, Zhang K, Sun T, Wang J, Guo Y, Yang L, et al. Epigenetic suppression of liver X receptor β in anterior cingulate cortex by HDAC5 drives CFA-induced chronic inflammatory pain. J Neuroinflammation. 2019;16:132 pubmed publisher
Xu B, Lang L, Li S, Guo J, Wang J, Wang D, et al. Cortisol Excess-Mediated Mitochondrial Damage Induced Hippocampal Neuronal Apoptosis in Mice Following Cold Exposure. Cells. 2019;8: pubmed publisher
Yu X, Li Z, Zhang Y, Xu M, Che Y, Tian X, et al. β-elemene inhibits radiation and hypoxia-induced macrophages infiltration via Prx-1/NF-κB/HIF-1α signaling pathway. Onco Targets Ther. 2019;12:4203-4211 pubmed publisher
Liang C, Xu J, Meng Q, Zhang B, Liu J, Hua J, et al. TGFB1-induced autophagy affects the pattern of pancreatic cancer progression in distinct ways depending on SMAD4 status. Autophagy. 2019;:1-15 pubmed publisher
Zhang K, Shen Q, Fang Y, Sun Y, Ding J, Chen Y. AZD9291 inactivates the PRC2 complex to mediate tumor growth inhibition. Acta Pharmacol Sin. 2019;: pubmed publisher
Cheng D, Tan Q, Zhu Q, Zhang J, Han X, Fang P, et al. TFEB Probably Involved in Midazolam-Disturbed Lysosomal Homeostasis and Its Induced β-Amyloid Accumulation. Front Hum Neurosci. 2019;13:108 pubmed publisher
Wei Y, Chen X, Liang C, Ling Y, Yang X, Ye X, et al. A Noncoding Regulatory RNAs Network Driven by Circ-CDYL Acts Specifically in the Early Stages Hepatocellular Carcinoma. Hepatology. 2019;: pubmed publisher
Lin Y, Wang S, Yang Z, Gao L, Zhou Z, Yu P, et al. Bilirubin alleviates alum-induced peritonitis through inactivation of NLRP3 inflammasome. Biomed Pharmacother. 2019;116:108973 pubmed publisher
Liu Y, Li R, Chen X, Zhi Y, Deng R, Zhou E, et al. Nonmuscle Myosin Heavy Chain IIA Recognizes Sialic Acids on Sialylated RNA Viruses To Suppress Proinflammatory Responses via the DAP12-Syk Pathway. MBio. 2019;10: pubmed publisher
Li M, Zhang H, Liu H, Tian H, Tang X, Bai Y, et al. Abnormal expression of TBX4 during anorectal development in rat embryos with ethylenethiourea-induced anorectal malformations. Biol Res. 2019;52:27 pubmed publisher
Jin H, Liu P, Kong L, Fei X, Gao Y, Wu T, et al. Identification of RE1-Silencing Transcription Factor as a Promoter of Metastasis in Pancreatic Cancer. Front Oncol. 2019;9:291 pubmed publisher
Du W, Dong Q, Zhang Z, Liu B, Zhou T, Xu R, et al. Stella protein facilitates DNA demethylation by disrupting the chromatin association of the RING finger-type E3 ubiquitin ligase UHRF1. J Biol Chem. 2019;294:8907-8917 pubmed publisher
Huang Y, Su R, Sheng Y, Dong L, Dong Z, Xu H, et al. Small-Molecule Targeting of Oncogenic FTO Demethylase in Acute Myeloid Leukemia. Cancer Cell. 2019;35:677-691.e10 pubmed publisher
Protopapas N, Hamilton L, Warkentin R, Xu W, Sutovsky P, Oko R. The perforatorium and postacrosomal sheath of rat spermatozoa share common developmental origins and protein constituents†. Biol Reprod. 2019;100:1461-1472 pubmed publisher
Zhou D, Zhuang J, Wang Y, Zhao D, Zhao L, Zhu S, et al. Propofol Alleviates DNA Damage Induced by Oxygen Glucose Deprivation and Reperfusion via FoxO1 Nuclear Translocation in H9c2 Cells. Front Physiol. 2019;10:223 pubmed publisher
Liu L, Zhang P, Zhang Z, Hu Q, He J, Liu H, et al. LXA4 ameliorates cerebrovascular endothelial dysfunction by reducing acute inflammation after subarachnoid hemorrhage in rats. Neuroscience. 2019;408:105-114 pubmed publisher
Leng B, Zhang Y, Liu X, Zhang Z, Liu Y, Wang H, et al. Astragaloside IV Suppresses High Glucose-Induced NLRP3 Inflammasome Activation by Inhibiting TLR4/NF-κB and CaSR. Mediators Inflamm. 2019;2019:1082497 pubmed publisher
Zhang S, Xu S, Duan H, Zhu Z, Yang Z, Cao J, et al. A novel, highly-water-soluble apigenin derivative provides neuroprotection following ischemia in male rats by regulating the ERK/Nrf2/HO-1 pathway. Eur J Pharmacol. 2019;855:208-215 pubmed publisher
Lv R, Du L, Liu X, Zhou F, Zhang Z, Zhang L. Rosmarinic acid attenuates inflammatory responses through inhibiting HMGB1/TLR4/NF-κB signaling pathway in a mouse model of Parkinson's disease. Life Sci. 2019;223:158-165 pubmed publisher
Chen Y, Wu T, Li H, Li X, Li Q, Zhu X, et al. Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation. Front Aging Neurosci. 2019;11:44 pubmed publisher
Zhang X, Qi Z, Yin H, Yang G. Interaction between p53 and Ras signaling controls cisplatin resistance via HDAC4- and HIF-1α-mediated regulation of apoptosis and autophagy. Theranostics. 2019;9:1096-1114 pubmed publisher
Yang P, Zhou Y, Xia Q, Yao L, Chang X. Astragaloside IV Regulates the PI3K/Akt/HO-1 Signaling Pathway and Inhibits H9c2 Cardiomyocyte Injury Induced by Hypoxia-Reoxygenation. Biol Pharm Bull. 2019;42:721-727 pubmed publisher
Yan B, Zhou H, Chu J, Cao X. Suppression of puerarin on polymethylmethacrylate-induced lesion of peri-implant by inhibiting NF-κB activation in vitro and in vivo. Pathol Res Pract. 2019;215:152372 pubmed publisher
Wang D, Li W, Zhao R, Chen L, Liu N, Tian Y, et al. Stabilized Peptide HDAC Inhibitors Derived from HDAC1 Substrate H3K56 for the Treatment of Cancer Stem-Like Cells In Vivo. Cancer Res. 2019;79:1769-1783 pubmed publisher
Qu M, Pan J, Wang L, Zhou P, Song Y, Wang S, et al. MicroRNA-126 Regulates Angiogenesis and Neurogenesis in a Mouse Model of Focal Cerebral Ischemia. Mol Ther Nucleic Acids. 2019;16:15-25 pubmed publisher
Han W, Wang C, Yang Z, Mu L, Wu M, Chen N, et al. SRT1720 retards renal fibrosis via inhibition of HIF1α /GLUT1 in diabetic nephropathy. J Endocrinol. 2019;: pubmed publisher
Wu R, Liu Y, Zhao Y, Bi Z, Yao Y, Liu Q, et al. m6A methylation controls pluripotency of porcine induced pluripotent stem cells by targeting SOCS3/JAK2/STAT3 pathway in a YTHDF1/YTHDF2-orchestrated manner. Cell Death Dis. 2019;10:171 pubmed publisher
Sun X, Xie Y, Sun X, Yao Y, Li H, Li Z, et al. The selective HDAC6 inhibitor Nexturastat A induces apoptosis, overcomes drug resistance and inhibits tumor growth in multiple myeloma. Biosci Rep. 2019;: pubmed publisher
Wang H, Wei W, Lan X, Liu N, Li Y, Ma H, et al. Neuroprotective Effect of Swertiamain on Cerebral Ischemia/Reperfusion Injury by Inducing the Nrf2 Protective Pathway. ACS Chem Neurosci. 2019;10:2276-2286 pubmed publisher
Monti D, Rigano M, Monti S, Peixoto H. Role of Antioxidants in the Protection from Aging-Related Diseases. Oxid Med Cell Longev. 2019;2019:7450693 pubmed publisher
Qin C, Zhang R, Lang Y, Shao A, Xu A, Feng W, et al. Bclaf1 critically regulates the type I interferon response and is degraded by alphaherpesvirus US3. PLoS Pathog. 2019;15:e1007559 pubmed publisher
Chen Y, Zhu D, Gao J, Xu Z, Tao S, Yin W, et al. Diminished membrane recruitment of Akt is instrumental in alcohol-associated osteopenia via the PTEN/Akt/GSK-3β/β-catenin axis. FEBS J. 2019;286:1101-1119 pubmed publisher
Yu H, Yao Y, Bu F, Chen Y, Wu Y, Yang Y, et al. Blockade of YAP alleviates hepatic fibrosis through accelerating apoptosis and reversion of activated hepatic stellate cells. Mol Immunol. 2019;107:29-40 pubmed publisher
Xu L, Wu Y, Yan F, Li C, Dai Z, You Q, et al. 5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole (DDO-7263), a novel Nrf2 activator targeting brain tissue, protects against MPTP-induced subacute Parkinson's disease in mice by inhibiting the NLRP3 inflammasome and protects PC12 cell. Free Radic Biol Med. 2019;134:288-303 pubmed publisher
Yang X, Zhao Y, Jia X, Wang C, Wu Y, Zhang L, et al. CP-25 combined with MTX/ LEF ameliorates the progression of adjuvant-induced arthritis by the inhibition on GRK2 translocation. Biomed Pharmacother. 2019;110:834-843 pubmed publisher
Fan Y, Ou L, Fan J, Li L, Wu X, Luo C, et al. HepaCAM Regulates Warburg Effect of Renal Cell Carcinoma via HIF-1α/NF-κB Signaling Pathway. Urology. 2019;127:61-67 pubmed publisher
Kong Q, Li N, Cheng H, Zhang X, Cao X, Qi T, et al. HSPA12A Is a Novel Player in Nonalcoholic Steatohepatitis via Promoting Nuclear PKM2-Mediated M1 Macrophage Polarization. Diabetes. 2019;68:361-376 pubmed publisher
Yuan C, Guo X, Zhou Q, Du F, Jiang W, Zhou X, et al. OAB-14, a bexarotene derivative, improves Alzheimer's disease-related pathologies and cognitive impairments by increasing β-amyloid clearance in APP/PS1 mice. Biochim Biophys Acta Mol Basis Dis. 2019;1865:161-180 pubmed publisher
Fu X, Zhang X, Yang H, Xu X, Hu Z, Yan J, et al. CUDC-907 displays potent antitumor activity against human pancreatic adenocarcinoma in vitro and in vivo through inhibition of HDAC6 to downregulate c-Myc expression. Acta Pharmacol Sin. 2019;40:677-688 pubmed publisher
Zhang K, Shi M, Niu Z, Chen X, Wei J, Miao Z, et al. Activation of brain endothelium by Escherichia coli K1 virulence factor cglD promotes polymorphonuclear leukocyte transendothelial migration. Med Microbiol Immunol. 2019;208:59-68 pubmed publisher
Ma Y, Ma B, Shang Y, Yin Q, Wang D, Xu S, et al. Flavonoid-Rich Ethanol Extract from the Leaves of Diospyros kaki Attenuates D-Galactose-Induced Oxidative Stress and Neuroinflammation-Mediated Brain Aging in Mice. Oxid Med Cell Longev. 2018;2018:8938207 pubmed publisher
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product information
CatalogNo :
17168-1-AP
AntigenName :
Histone-H3
Package :
150UL
Price :
99 USD
FullName :
histone cluster 2, H3a
Immunogen :
Fusion Protein
Species :
arabidopsis, bovine, human, monkey, mouse, pig, rat, swine, xenopus laevis, yellow catfish
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
H3/n, H3/o, H3F2, H3FM, HIST2H3A, HIST2H3C, HIST2H3D, histone cluster 2, H3a, Histone H3, Histone H3.2, Histone H3/m, Histone H3/o
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC015544
Category :
Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:50 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.