This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
SPHK2
catalog :
17096-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 8
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 1d
  • western blot; human; loading ...; fig 4b
Neubauer H, Tea M, Zebol J, Gliddon B, Stefanidis C, Moretti P, et al. Cytoplasmic dynein regulates the subcellular localization of sphingosine kinase 2 to elicit tumor-suppressive functions in glioblastoma. Oncogene. 2019;38:1151-1165 pubmed publisher
  • immunocytochemistry; mouse; loading ...; fig 3
  • western blot; mouse; loading ...; fig 1b
  • immunoprecipitation; human; loading ...; fig 2b
  • immunocytochemistry; human; loading ...; fig 3
  • western blot; human; loading ...; fig 1b
Neubauer H, Pitson S. Validation of commercially available sphingosine kinase 2 antibodies for use in immunoblotting, immunoprecipitation and immunofluorescence. F1000Res. 2016;5:2825 pubmed publisher
Xiao J, Lin H, Liu B, Xia Z, Zhang J, Jin J. Decreased S1P and SPHK2 are involved in pancreatic acinar cell injury. Biomark Med. 2019;13:627-637 pubmed publisher
Riento K, Zhang Q, Clark J, Begum F, Stephens E, Wakelam M, et al. Flotillin proteins recruit sphingosine to membranes and maintain cellular sphingosine-1-phosphate levels. PLoS ONE. 2018;13:e0197401 pubmed publisher
Panneer Selvam S, Roth B, Nganga R, Kim J, Cooley M, Helke K, et al. Balance between senescence and apoptosis is regulated by telomere damage-induced association between p16 and caspase-3. J Biol Chem. 2018;293:9784-9800 pubmed publisher
Powell J, Lewis A, Zhu W, Toubia J, Pitman M, Wallington Beddoe C, et al. Targeting sphingosine kinase 1 induces MCL1-dependent cell death in acute myeloid leukemia. Blood. 2017;129:771-782 pubmed publisher
Neubauer H, Pham D, Zebol J, Moretti P, Peterson A, Leclercq T, et al. An oncogenic role for sphingosine kinase 2. Oncotarget. 2016;7:64886-64899 pubmed publisher
Liu X, Ren K, Suo R, Xiong S, Zhang Q, Mo Z, et al. ApoA-I induces S1P release from endothelial cells through ABCA1 and SR-BI in a positive feedback manner. J Physiol Biochem. 2016;72:657-667 pubmed
product information
CatalogNo :
17096-1-AP
AntigenName :
SPHK2
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
sphingosine kinase 2
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
SK 2, sphingosine kinase 2, SPHK2, SPK 2
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC010671
Category :
Apoptosis;Binding Proteins;Cell Cycle;Membrane Proteins;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:200 ; IP 1:800 ; WB 1:3000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.