This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
TIMP1
catalog :
16644-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry
citations: 23
Reference
He X, Huang Z, Liu P, Li Q, Wang M, Qiu M, et al. Apatinib Inhibits the Invasion and Metastasis of Liver Cancer Cells by Downregulating MMP-Related Proteins via Regulation of the NF-κB Signaling Pathway. Biomed Res Int. 2020;2020:3126182 pubmed publisher
Zhang Y, Luo L, Wang Y, Zhu N, Zhao T, Qin L. Total saponins from Lilium lancifolium: a promising alternative to inhibit the growth of gastric carcinoma cells. J Cancer. 2020;11:4261-4273 pubmed publisher
Xu S, Mao Y, Wu J, Feng J, Li J, Wu L, et al. TGF-β/Smad and JAK/STAT pathways are involved in the anti-fibrotic effects of propylene glycol alginate sodium sulphate on hepatic fibrosis. J Cell Mol Med. 2020;24:5224-5237 pubmed publisher
Su Y, Luo H, Huang C, Liu T, Huang E, Sung M, et al. Galectin-1 Overexpression Activates the FAK/PI3K/AKT/mTOR Pathway and Is Correlated with Upper Urinary Urothelial Carcinoma Progression and Survival. Cells. 2020;9: pubmed publisher
Fu S, Li Y, Wu Y, Yue Y, Yang D. Icariside II improves myocardial fibrosis in spontaneously hypertensive rats by inhibiting collagen synthesis. J Pharm Pharmacol. 2020;72:227-235 pubmed publisher
Li J, Liu L, Zhao Q, Chen M. Role of Interleukin-17 in Pathogenesis of Intestinal Fibrosis in Mice. Dig Dis Sci. 2019;: pubmed publisher
Liu X, Qu C, Shi S, Ye T, Wang L, Liu S, et al. The Reversal Effect of Sigma-1 Receptor (S1R) Agonist, SA4503, on Atrial Fibrillation After Depression and Its Underlying Mechanism. Front Physiol. 2019;10:1346 pubmed publisher
Zhou X, Xiong J, Lu S, Luo L, Chen Z, Yang F, et al. Inhibitory Effect of Corilagin on miR-21-Regulated Hepatic Fibrosis Signaling Pathway. Am J Chin Med. 2019;47:1541-1569 pubmed publisher
Wang X, Lin L, Chai X, Wu Y, Li Y, Liu X. Hypoxic mast cells accelerate the proliferation, collagen accumulation and phenotypic alteration of human lung fibroblasts. Int J Mol Med. 2019;: pubmed publisher
Chen I, Luo H, Su Y, Huang C, Chiang P, Yu C, et al. Aristolochic Acid Affects Upper Tract Urothelial Cancer Behavior through the MAPK Pathway. Molecules. 2019;24: pubmed publisher
Dias H, de Oliveira J, Donadio M, Kimura S. Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts. PLoS ONE. 2019;14:e0222202 pubmed publisher
Cecen B, Keles D, Oktay G, Kozaci L. Effects of simvastatin on matrix metalloproteinase regulation in IL-1β-induced SW1353 cells. Chem Biol Interact. 2019;310:108730 pubmed publisher
Chen J, Li D, Luo E. Telbivudine antagonizes TLR4 to inhibit the epithelial-to-mesenchymal transition in human proximal tubular epithelial cells in vitro. Int Immunopharmacol. 2019;74:105683 pubmed publisher
Li X, Liu Y, Yue W, Tan Y, Wang H, Zhang L, et al. A Compound of Chinese Herbs Protects against Alcoholic Liver Fibrosis in Rats via the TGF-β1/Smad Signaling Pathway. Evid Based Complement Alternat Med. 2019;2019:9121347 pubmed publisher
Wang J, Du L, Fu Y, Jiang P, Wang X. ZnO nanoparticles inhibit the activity of Porphyromonas gingivalis and Actinomyces naeslundii and promote the mineralization of the cementum. BMC Oral Health. 2019;19:84 pubmed publisher
Yu Z, Jv Y, Cai L, Tian X, Huo X, Wang C, et al. Gambogic acid attenuates liver fibrosis by inhibiting the PI3K/AKT and MAPK signaling pathways via inhibiting HSP90. Toxicol Appl Pharmacol. 2019;371:63-73 pubmed publisher
Zhang L, Liu Y, Huang Z, Nan L, Wang F, Zhou S, et al. Toxicity Effects of Methylene Blue on Rat Intervertebral Disc Annulus Fibrosus Cells. Pain Physician. 2019;22:155-164 pubmed
Yu H, Zeng R, Lin Y, Li X, Tasneem S, Yang Z, et al. Kadsura heteroclita stem suppresses the onset and progression of adjuvant-induced arthritis in rats. Phytomedicine. 2019;58:152876 pubmed publisher
Du M, Wang Y, Liu Z, Wang L, Cao Z, Zhang C, et al. Effects of IL-1β on MMP-9 Expression in Cementoblast-Derived Cell Line and MMP-Mediated Degradation of Type I Collagen. Inflammation. 2019;42:413-425 pubmed publisher
Tian Y, Chen K, Zulkefli N, Maner R, Hsieh C. Evaluation of the Inhibitory Effects of Genipin on the Fluoxetine-Induced Invasive and Metastatic Model in Human HepG2 Cells. Molecules. 2018;23: pubmed publisher
He X, Shi L, Qiu M, Li Q, Wang M, Xiong Z, et al. Molecularly targeted anti-cancer drugs inhibit the invasion and metastasis of hepatocellular carcinoma by regulating the expression of MMP and TIMP gene families. Biochem Biophys Res Commun. 2018;504:878-884 pubmed publisher
Fang C, Wu C, Liao Y, Huang S, Chen M, Chen Y. AAV serotype 8-mediated liver specific GNMT expression delays progression of hepatocellular carcinoma and prevents carbon tetrachloride-induced liver damage. Sci Rep. 2018;8:13802 pubmed publisher
Chen Y, Wei J, Zhang Y, Sun W, Li Z, Wang Q, et al. Anti-endometriosis Mechanism of Jiawei Foshou San Based on Network Pharmacology. Front Pharmacol. 2018;9:811 pubmed publisher
product information
CatalogNo :
16644-1-AP
AntigenName :
TIMP1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
TIMP metallopeptidase inhibitor 1
Immunogen :
Fusion Protein
Species :
human, mouse, rabbit, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CLGI, Collagenase inhibitor, EPA, EPO, HCI, Metalloproteinase inhibitor 1, TIMP, TIMP 1, TIMP1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000866
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Development;Disease Related;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:50 ; IHC 1:50 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.