This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Aquaporin 4
catalog :
16473-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, rat
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 3
Guan Y, Li L, Chen J, Lu H. Effect of AQP4-RNAi in treating traumatic brain edema: Multi-modal MRI and histopathological changes of early stage edema in a rat model. Exp Ther Med. 2020;19:2029-2036 pubmed publisher
  • immunohistochemistry; human; 1:50; fig 4
Chen A, Akinyemi R, Hase Y, Firbank M, Ndung u M, Foster V, et al. Frontal white matter hyperintensities, clasmatodendrosis and gliovascular abnormalities in ageing and post-stroke dementia. Brain. 2016;139:242-58 pubmed publisher
Liu Y, Ma Y, Du B, Wang Y, Yang G, Bi X. Mesenchymal Stem Cells Attenuated Blood-Brain Barrier Disruption via Downregulation of Aquaporin-4 Expression in EAE Mice. Mol Neurobiol. 2020;: pubmed publisher
Wang H, Chen H, Jin J, Liu Q, Zhong D, Li G. Inhibition of the NLRP3 inflammasome reduces brain edema and regulates the distribution of aquaporin-4 after cerebral ischaemia-reperfusion. Life Sci. 2020;251:117638 pubmed publisher
Zhang J, Li S, Liu J, Li L, Deng F, Baikeli B, et al. Higher expression levels of aquaporin (AQP)1 and AQP5 in the lungs of arid-desert living Lepus yarkandensis. J Anim Physiol Anim Nutr (Berl). 2019;: pubmed publisher
Zhang J, Li S, Deng F, Baikeli B, Yu W, Liu G. Distribution of aquaporins and sodium transporters in the gastrointestinal tract of a desert hare, Lepus yarkandensis. Sci Rep. 2019;9:16639 pubmed publisher
Zhang J, Li S, Deng F, Baikeli B, Huang S, Wang B, et al. Higher Expression Levels of Aquaporin Family of Proteins in the Kidneys of Arid-Desert Living Lepus yarkandensis. Front Physiol. 2019;10:1172 pubmed publisher
He F, Dai R, Zhou X, Li X, Song X, Yan H, et al. Protective effect of 4-Methoxy benzyl alcohol on the neurovascular unit after cerebral ischemia reperfusion injury. Biomed Pharmacother. 2019;118:109260 pubmed publisher
Fang Y, Tian Y, Huang Q, Wan Y, Xu L, Wang W, et al. Deficiency of TREK-1 potassium channel exacerbates blood-brain barrier damage and neuroinflammation after intracerebral hemorrhage in mice. J Neuroinflammation. 2019;16:96 pubmed publisher
Cotzomi E, Stathopoulos P, Lee C, Ritchie A, Soltys J, Delmotte F, et al. Early B cell tolerance defects in neuromyelitis optica favour anti-AQP4 autoantibody production. Brain. 2019;142:1598-1615 pubmed publisher
Huang B, Miao H, Yuan Y, Qiu F, Liu X, Liu Z, et al. PEDF decreases cardiomyocyte edema during oxygen‑glucose deprivation and recovery via inhibiting lactate accumulation and expression of AQP1. Int J Mol Med. 2019;43:1979-1990 pubmed publisher
Tian Y, He Y, Zhang L, Zhang J, Xu L, Ma Y, et al. Role of vasodilator-stimulated phosphoprotein in human cytomegalovirus-induced hyperpermeability of human endothelial cells. Exp Ther Med. 2018;16:1295-1303 pubmed publisher
Tian Y, Xu L, He Y, Xu X, Li K, Ma Y, et al. Knockdown of RAC1 and VASP gene expression inhibits breast cancer cell migration. Oncol Lett. 2018;16:2151-2160 pubmed publisher
Guo J, Mi X, Zhan R, Li M, Wei L, Sun J. Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats. Med Sci Monit. 2018;24:4204-4212 pubmed publisher
Li M, Tian X, An R, Yang M, Zhang Q, Xiang F, et al. All-Trans Retinoic Acid Ameliorates the Early Experimental Cerebral Ischemia-Reperfusion Injury in Rats by Inhibiting the Loss of the Blood-Brain Barrier via the JNK/P38MAPK Signaling Pathway. Neurochem Res. 2018;43:1283-1296 pubmed publisher
Khalfallah Y, Kuta R, Grasmuck C, Prat A, Durham H, Vande Velde C. TDP-43 regulation of stress granule dynamics in neurodegenerative disease-relevant cell types. Sci Rep. 2018;8:7551 pubmed publisher
He F, Duan X, Dai R, Wang W, Yang C, Lin Q. PROTECTIVE EFFECTS OF ETHYL ACETATE EXTRACTION FROM GASTRODIA ELATA BLUME ON BLOOD-BRAIN BARRIER IN FOCAL CEREBRAL ISCHEMIA REPERFUSION. Afr J Tradit Complement Altern Med. 2016;13:199-209 pubmed publisher
Shepard M, Padmanaban V, Edwards N, Chittiboina P, Ray Chaudhury A, Heiss J. Discovery of Aquaporin-1 and Aquaporin-4 Expression in an Intramedullary Spinal Cord Ependymal Cyst: Case Report. World Neurosurg. 2017;107:1046.e1-1046.e7 pubmed publisher
Zhang D, Zou M, Zhang Y, Fu W, Xu T, Wang J, et al. A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation. Exp Neurol. 2017;297:1-13 pubmed publisher
Zhou Y, Huang X, Zhao T, Qiao M, Zhao X, Zhao M, et al. Hypoxia augments LPS-induced inflammation and triggers high altitude cerebral edema in mice. Brain Behav Immun. 2017;64:266-275 pubmed publisher
Hase Y, Craggs L, Hase M, Stevenson W, Slade J, Lopez D, et al. Effects of environmental enrichment on white matter glial responses in a mouse model of chronic cerebral hypoperfusion. J Neuroinflammation. 2017;14:81 pubmed publisher
He F, Duan X, Dai R, Li Y, Lin Q. Protective Effect of 4-Methoxy Benzyl Alcohol on the Blood-Brain Barrier after Cerebral Ischemia Reperfusion Injury. J Stroke Cerebrovasc Dis. 2017;26:1258-1265 pubmed publisher
Pecorelli A, Natrella F, Belmonte G, Miracco C, Cervellati F, Ciccoli L, et al. NADPH oxidase activation and 4-hydroxy-2-nonenal/aquaporin-4 adducts as possible new players in oxidative neuronal damage presents in drug-resistant epilepsy. Biochim Biophys Acta. 2015;1852:507-19 pubmed publisher
product information
CatalogNo :
16473-1-AP
AntigenName :
Aquaporin 4
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
aquaporin 4
Immunogen :
Fusion Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AQP 4, AQP4, aquaporin 4, HMIWC2, MIWC, NMO-IgG, WCH4
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC022286
Category :
Development;Membrane Proteins;Plasma/Serum;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:2000 ; IP 1:300 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.