SMCR7/MID49 | Proteintech Group 16413-1-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

Proteintech Group

product type :

antibody

product name :

SMCR7/MID49

catalog :

16413-1-AP

quantity :

150UL

price :

299 USD

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human, mouse

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, western blot knockout validation

citations: 27

Published Application/Species/Sample/Dilution	Reference
western blot knockout validation; human; fig 1a	Otera H, Miyata N, Kuge O, Mihara K. Drp1-dependent mitochondrial fission via MiD49/51 is essential for apoptotic cristae remodeling. J Cell Biol. 2016;212:531-44 pubmed publisher
western blot; mouse; fig s2	Korwitz A, Merkwirth C, Richter Dennerlein R, TrÃ¶der S, Sprenger H, QuirÃ³s P, et al. Loss of OMA1 delays neurodegeneration by preventing stress-induced OPA1 processing in mitochondria. J Cell Biol. 2016;212:157-66 pubmed publisher
	Ma D, Zheng B, Liu H, Zhao Y, Liu X, Zhang X, et al. Klf5 down-regulation induces vascular senescence through eIF5a depletion and mitochondrial fission. PLoS Biol. 2020;18:e3000808 pubmed publisher
	Chen C, Tsao N, Zhang W, Chang Z. NME3 Regulates Mitochondria to Reduce ROS-Mediated Genome Instability. Int J Mol Sci. 2020;21: pubmed publisher
	Bai L, Liang J, Li L, Li E. Downregulation of MiD49 contributes to tumor growth and metastasis of human pancreatic cancer. Oncol Rep. 2020;43:1208-1220 pubmed publisher
	Nagashima S, Tábara L, Tilokani L, Paupe V, Anand H, Pogson J, et al. Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division. Science. 2020;367:1366-1371 pubmed publisher
	Tokuyama T, Hirai A, Shiiba I, Ito N, Matsuno K, Takeda K, et al. Mitochondrial Dynamics Regulation in Skin Fibroblasts from Mitochondrial Disease Patients. Biomolecules. 2020;10: pubmed publisher
	Djajawi T, Liu L, Gong J, Huang A, Luo M, Xu Z, et al. MARCH5 requires MTCH2 to coordinate proteasomal turnover of the MCL1:NOXA complex. Cell Death Differ. 2020;: pubmed publisher
	Yasukawa K, Kinoshita D, Yaku K, Nakagawa T, Koshiba T. The microRNAs miR-302b and miR-372 regulate mitochondrial metabolism via the SLC25A12 transporter, which controls MAVS-mediated antiviral innate immunity. J Biol Chem. 2020;295:444-457 pubmed publisher
	Nagashima S, Takeda K, Ohno N, Ishido S, Aoki M, Saitoh Y, et al. MITOL deletion in the brain impairs mitochondrial structure and ER tethering leading to oxidative stress. Life Sci Alliance. 2019;2: pubmed publisher
	Geng J, Liu W, Gao J, Jiang C, Fan T, Sun Y, et al. Andrographolide alleviates parkinsonism in MPTP-PD mice via targeting DRP1-mediated mitochondrial fission. Br J Pharmacol. 2019;: pubmed publisher
	Yedida G, Milani M, Cohen G, Varadarajan S. Apogossypol-mediated reorganisation of the endoplasmic reticulum antagonises mitochondrial fission and apoptosis. Cell Death Dis. 2019;10:521 pubmed publisher
	Lee L, Seager R, Nakamura Y, Wilkinson K, Henley J. Parkin-mediated ubiquitination contributes to the constitutive turnover of mitochondrial fission factor (Mff). PLoS ONE. 2019;14:e0213116 pubmed publisher
	Xian H, Yang Q, Xiao L, Shen H, Liou Y. STX17 dynamically regulated by Fis1 induces mitophagy via hierarchical macroautophagic mechanism. Nat Commun. 2019;10:2059 pubmed publisher
	Liu X, Huang S, Wang F, Zheng L, Lu J, Chen J, et al. Huangqi-Danshen Decoction Ameliorates Adenine-Induced Chronic Kidney Disease by Modulating Mitochondrial Dynamics. Evid Based Complement Alternat Med. 2019;2019:9574045 pubmed publisher
	Chen C, Wang H, Huang C, Huang C, Lim W, Tu I, et al. Two separate functions of NME3 critical for cell survival underlie a neurodegenerative disorder. Proc Natl Acad Sci U S A. 2019;116:566-574 pubmed publisher
	Zhong X, Cui P, Cai Y, Wang L, He X, Long P, et al. Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells. Cell Metab. 2019;29:979-992.e4 pubmed publisher
	Xiong P, Tian L, Dunham Snary K, Chen K, Mewburn J, Neuber Hess M, et al. Biventricular Increases in Mitochondrial Fission Mediator (MiD51) and Proglycolytic Pyruvate Kinase (PKM2) Isoform in Experimental Group 2 Pulmonary Hypertension-Novel Mitochondrial Abnormalities. Front Cardiovasc Med. 2018;5:195 pubmed publisher
	Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, et al. Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology. Cell Rep. 2018;23:2989-3005 pubmed publisher
	Bartsakoulia M, Pyle A, Troncoso Chandía D, Vial Brizzi J, Paz Fiblas M, Duff J, et al. A novel mechanism causing imbalance of mitochondrial fusion and fission in human myopathies. Hum Mol Genet. 2018;27:1186-1195 pubmed publisher
	Wang L, Zhang T, Wang L, Cai Y, Zhong X, He X, et al. Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission. EMBO J. 2017;36:1330-1347 pubmed publisher
	Guedouari H, Daigle T, Scorrano L, Hébert Chatelain E. Sirtuin 5 protects mitochondria from fragmentation and degradation during starvation. Biochim Biophys Acta Mol Cell Res. 2017;1864:169-176 pubmed publisher
	Zhou L, Li R, Liu C, Sun T, Htet Aung L, Chen C, et al. Foxo3a inhibits mitochondrial fission and protects against doxorubicin-induced cardiotoxicity by suppressing MIEF2. Free Radic Biol Med. 2017;104:360-370 pubmed publisher
	Wu W, Lin C, Wu K, Jiang L, Wang X, Li W, et al. FUNDC1 regulates mitochondrial dynamics at the ER-mitochondrial contact site under hypoxic conditions. EMBO J. 2016;35:1368-84 pubmed publisher
	Vannuvel K, Van Steenbrugge M, Demazy C, Ninane N, Fattaccioli A, Fransolet M, et al. Effects of a Sublethal and Transient Stress of the Endoplasmic Reticulum on the Mitochondrial Population. J Cell Physiol. 2016;231:1913-31 pubmed publisher
	Xu S, Cherok E, Das S, Li S, Roelofs B, Ge S, et al. Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein. Mol Biol Cell. 2016;27:349-59 pubmed publisher
	Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, et al. Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization. Cell Death Differ. 2016;23:380-92 pubmed publisher

product information

CatalogNo :

16413-1-AP

AntigenName :

SMCR7/MID49

Package :

150UL

Price :

299 USD

Exsists20ul :

20ul trial size available

FullName :

Smith-Magenis syndrome chromosome region, candidate 7

Immunogen :

Recombinant Protein

Species :

human, mouse, rat

Host :

Rabbit

IsConjugated :

Unconjugated

AntigenSpecies :

human

Application :

WB, IHC, IF, ELISA

Clonlity :

Polyclonal

IsoType :

IgG

Synonyms :

MID49, MIEF2, SMCR7

PrimaryOrSecondary :

Primary

AntibodyBuffer :

PBS with 0.1% sodium azide and 50% glycerol pH 7.3.

GenBankNo :

BC014973

Category :

Binding Proteins;Membrane Proteins;

PurifyMethod :

Antigen affinity purification

NewAb :

False

IsSellable :

True

Feature :

siRNA

AppTiter :

IHC 1:50 ; WB 1:600 ;