This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
MRPL44
catalog :
16394-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 18
Published Application/Species/Sample/DilutionReference
  • western blot; human; fig 3g
Maiti P, Kim H, Tu Y, Barrientos A. Human GTPBP10 is required for mitoribosome maturation. Nucleic Acids Res. 2018;46:11423-11437 pubmed publisher
  • western blot; mouse; 1:1000; fig 4
Richman T, Spahr H, Ermer J, Davies S, Viola H, Bates K, et al. Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun. 2016;7:11884 pubmed publisher
Lee R, Gao J, Siira S, Shearwood A, Ermer J, Hofferek V, et al. Cardiolipin is required for membrane docking of mitochondrial ribosomes and protein synthesis. J Cell Sci. 2020;133: pubmed publisher
Rudler D, Hughes L, Perks K, Richman T, Kuznetsova I, Ermer J, et al. Fidelity of translation initiation is required for coordinated respiratory complex assembly. Sci Adv. 2019;5:eaay2118 pubmed publisher
Ferreira N, Perks K, Rossetti G, Rudler D, Hughes L, Ermer J, et al. Stress signaling and cellular proliferation reverse the effects of mitochondrial mistranslation. EMBO J. 2019;38:e102155 pubmed publisher
Pulman J, Ruzzenente B, Bianchi L, Rio M, Boddaert N, Munnich A, et al. Mutations in the MRPS28 gene encoding the small mitoribosomal subunit protein bS1m in a patient with intrauterine growth retardation, craniofacial dysmorphism and multisystemic involvement. Hum Mol Genet. 2019;28:1445-1462 pubmed publisher
Jackson C, Huemer M, Bolognini R, Martin F, Szinnai G, Donner B, et al. A variant in MRPS14 (uS14m) causes perinatal hypertrophic cardiomyopathy with neonatal lactic acidosis, growth retardation, dysmorphic features and neurological involvement. Hum Mol Genet. 2019;28:639-649 pubmed publisher
Siira S, Rossetti G, Richman T, Perks K, Ermer J, Kuznetsova I, et al. Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep. 2018;19: pubmed publisher
Lavdovskaia E, Kolander E, Steube E, Mai M, Urlaub H, Richter Dennerlein R. The human Obg protein GTPBP10 is involved in mitoribosomal biogenesis. Nucleic Acids Res. 2018;46:8471-8482 pubmed publisher
Kühl I, Miranda M, Atanassov I, Kuznetsova I, Hinze Y, Mourier A, et al. Transcriptomic and proteomic landscape of mitochondrial dysfunction reveals secondary coenzyme Q deficiency in mammals. elife. 2017;6: pubmed publisher
Perks K, Ferreira N, Richman T, Ermer J, Kuznetsova I, Shearwood A, et al. Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv. 2017;3:e1700677 pubmed publisher
Mitsopoulos P, Lapohos O, Weraarpachai W, Antonicka H, Chang Y, Madrenas J. Stomatin-like protein 2 deficiency results in impaired mitochondrial translation. PLoS ONE. 2017;12:e0179967 pubmed publisher
Antonicka H, Choquet K, Lin Z, Gingras A, Kleinman C, Shoubridge E. A pseudouridine synthase module is essential for mitochondrial protein synthesis and cell viability. EMBO Rep. 2017;18:28-38 pubmed publisher
Rackham O, Busch J, Matic S, Siira S, Kuznetsova I, Atanassov I, et al. Hierarchical RNA Processing Is Required for Mitochondrial Ribosome Assembly. Cell Rep. 2016;16:1874-90 pubmed publisher
Richter U, Lahtinen T, Marttinen P, Suomi F, Battersby B. Quality control of mitochondrial protein synthesis is required for membrane integrity and cell fitness. J Cell Biol. 2015;211:373-89 pubmed publisher
Yeo J, Skinner J, Bird M, Formosa L, Zhang J, Kluck R, et al. A Role for the Mitochondrial Protein Mrpl44 in Maintaining OXPHOS Capacity. PLoS ONE. 2015;10:e0134326 pubmed publisher
Richman T, Ermer J, Davies S, Perks K, Viola H, Shearwood A, et al. Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet. 2015;11:e1005089 pubmed publisher
Antonicka H, Shoubridge E. Mitochondrial RNA Granules Are Centers for Posttranscriptional RNA Processing and Ribosome Biogenesis. Cell Rep. 2015;10:920-932 pubmed publisher
product information
CatalogNo :
16394-1-AP
AntigenName :
MRPL44
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
mitochondrial ribosomal protein L44
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
L44MT, MRP L44, MRPL44
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC012058
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:50 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.