This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Lin28B-specific
catalog :
16178-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry
citations: 8
Published Application/Species/Sample/DilutionReference
  • western blot; human; loading ...; fig 3d
Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, et al. Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer. Cancer Res. 2016;76:3629-43 pubmed publisher
Zhang Y, Li C, Hu C, Wu Q, Cai Y, Xing S, et al. Lin28 enhances de novo fatty acid synthesis to promote cancer progression via SREBP-1. EMBO Rep. 2019;:e48115 pubmed publisher
Lei D, Shao Z, Zhou X, Yuan H. Synergistic neuroprotective effect of rasagiline and idebenone against retinal ischemia-reperfusion injury via the Lin28-let-7-Dicer pathway. Oncotarget. 2018;9:12137-12153 pubmed publisher
Wang X, Zhang H, Bai M, Ning T, Ge S, Deng T, et al. Exosomes Serve as Nanoparticles to Deliver Anti-miR-214 to Reverse Chemoresistance to Cisplatin in Gastric Cancer. Mol Ther. 2018;26:774-783 pubmed publisher
Dong N, Liu Y, Zhang T, Zhao L, Tian J, Ruan J. Different expression patterns of Lin28 and Lin28b in mouse molar development. Arch Oral Biol. 2017;82:280-285 pubmed publisher
Wu T, Li Y, Ma S, Bing Liu -, Zhang W, Sun Z. Expression and associations of TRAF1, BMI-1, ALDH1, and Lin28B in oral squamous cell carcinoma. Tumour Biol. 2017;39:1010428317695930 pubmed publisher
Zhan M, Wen F, Liu L, Chen Z, Wei H, Zhou H. JMJD1A promotes tumorigenesis and forms a feedback loop with EZH2/let-7c in NSCLC cells. Tumour Biol. 2016;37:11237-47 pubmed publisher
Sangiao Alvarellos S, Manfredi Lozano M, Ruiz Pino F, León S, Morales C, Cordido F, et al. Testicular expression of the Lin28/let-7 system: Hormonal regulation and changes during postnatal maturation and after manipulations of puberty. Sci Rep. 2015;5:15683 pubmed publisher
product information
CatalogNo :
16178-1-AP
AntigenName :
Lin28B-specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
lin-28 homolog B (C. elegans)
Immunogen :
Peptide
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
CSDD2, lin 28 homolog B (C. elegans), Lin 28B, Lin28, LIN28B, Protein lin 28 homolog B
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_001004317
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Stem Cells;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:50 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.