This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Presenilin-1-Specific
catalog :
16163-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 6
Reference
Inoue Y, Ueda M, Masuda T, Misumi Y, Yamashita T, Ando Y. Memantine, a Noncompetitive N-Methyl-D-Aspartate Receptor Antagonist, Attenuates Cerebral Amyloid Angiopathy by Increasing Insulin-Degrading Enzyme Expression. Mol Neurobiol. 2019;: pubmed publisher
Zhang Y, Xie J, Xu X, Hu J, Xu T, Jin S, et al. Liraglutide Ameliorates Hyperhomocysteinemia-Induced Alzheimer-Like Pathology and Memory Deficits in Rats via Multi-molecular Targeting. Neurosci Bull. 2019;: pubmed publisher
Zhu B, Long Y, Luo W, Yan Z, Lai Y, Zhao L, et al. MMP13 inhibition rescues cognitive decline in Alzheimer transgenic mice via BACE1 regulation. Brain. 2019;142:176-192 pubmed publisher
Shentu Y, Huo Y, Feng X, Gilbert J, Zhang Q, Liuyang Z, et al. CIP2A Causes Tau/APP Phosphorylation, Synaptopathy, and Memory Deficits in Alzheimer's Disease. Cell Rep. 2018;24:713-723 pubmed publisher
Mushtaq M, Pangigadde P, Darekar S, Dissen E, Kashuba E. Rat embryonic fibroblasts immortalized by MRPS18-2 protein are target for NK-cells. Oncotarget. 2017;8:64907-64917 pubmed publisher
Cai D, Yuan M, Jia Y, Liu H, Hu Y, Zhao R. Maternal gestational betaine supplementation-mediated suppression of hepatic cyclin D2 and presenilin1 gene in newborn piglets is associated with epigenetic regulation of the STAT3-dependent pathway. J Nutr Biochem. 2015;26:1622-31 pubmed publisher
product information
CatalogNo :
16163-1-AP
AntigenName :
Presenilin-1-Specific
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
presenilin 1
Immunogen :
Peptide
Species :
human, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
AD3, FAD, Presenilin-1, Protein S182, PS 1, PS1, PS1 CTF12, PSEN1, PSNL1, S182
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
NM_000021
Category :
Apoptosis;Binding Proteins;Ciliary Protein;Cytoskeleton/Scaffold Proteins;Disease Related;Membrane Proteins;Metabolism;Neurology;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:100 ; IP 1:1000 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.