This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PMPCB
catalog :
16064-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 11
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; 1:2000; fig 2
Nabhan J, Wood K, Rao V, Morin J, Bhamidipaty S, LaBranche T, et al. Intrathecal delivery of frataxin mRNA encapsulated in lipid nanoparticles to dorsal root ganglia as a potential therapeutic for Friedreich's ataxia. Sci Rep. 2016;6:20019 pubmed publisher
Guo X, Aviles G, Liu Y, Tian R, Unger B, Lin Y, et al. Mitochondrial stress is relayed to the cytosol by an OMA1-DELE1-HRI pathway. Nature. 2020;579:427-432 pubmed publisher
Bonello F, Hassoun S, Mouton Liger F, Shin Y, Muscat A, Tesson C, et al. LRRK2 impairs PINK1/Parkin-dependent mitophagy via its kinase activity: pathologic insights into Parkinson's disease. Hum Mol Genet. 2019;28:1645-1660 pubmed publisher
Bertolin G, Bulteau A, Alves Guerra M, Burel A, Lavault M, Gavard O, et al. Aurora kinase A localises to mitochondria to control organelle dynamics and energy production. elife. 2018;7: pubmed publisher
Zurita Rendón O, Shoubridge E. LONP1 Is Required for Maturation of a Subset of Mitochondrial Proteins, and Its Loss Elicits an Integrated Stress Response. Mol Cell Biol. 2018;38: pubmed publisher
Soutar M, Kempthorne L, Miyakawa S, Annuario E, Melandri D, Harley J, et al. AKT signalling selectively regulates PINK1 mitophagy in SHSY5Y cells and human iPSC-derived neurons. Sci Rep. 2018;8:8855 pubmed publisher
Jian F, Chen D, Chen L, Yan C, Lu B, Zhu Y, et al. Sam50 Regulates PINK1-Parkin-Mediated Mitophagy by Controlling PINK1 Stability and Mitochondrial Morphology. Cell Rep. 2018;23:2989-3005 pubmed publisher
Saita S, Tatsuta T, Lampe P, König T, Ohba Y, Langer T. PARL partitions the lipid transfer protein STARD7 between the cytosol and mitochondria. EMBO J. 2018;37: pubmed publisher
Saita S, Nolte H, Fiedler K, Kashkar H, Venne A, Zahedi R, et al. PARL mediates Smac proteolytic maturation in mitochondria to promote apoptosis. Nat Cell Biol. 2017;19:318-328 pubmed publisher
Gautier C, Erpapazoglou Z, Mouton Liger F, Muriel M, Cormier F, Bigou S, et al. The endoplasmic reticulum-mitochondria interface is perturbed in PARK2 knockout mice and patients with PARK2 mutations. Hum Mol Genet. 2016;25:2972-2984 pubmed
Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, et al. Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016;97:1-14 pubmed publisher
product information
CatalogNo :
16064-1-AP
AntigenName :
PMPCB
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
peptidase (mitochondrial processing) beta
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Beta MPP, MPP11, MPPB, MPPP52, P 52, PMPCB
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC010398
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:25 ; IHC 1:100 ; IP 1:500 ; WB 1:1500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.