This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
CISD1
catalog :
16006-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, western blot knockout validation, immunohistochemistry knockout validation
citations: 18
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry knockout validation; mouse; 1:100; fig 1a
  • western blot knockout validation; mouse; fig 1d
Geldenhuys W, Benkovic S, Lin L, Yonutas H, Crish S, Sullivan P, et al. MitoNEET (CISD1) Knockout Mice Show Signs of Striatal Mitochondrial Dysfunction and a Parkinson's Disease Phenotype. ACS Chem Neurosci. 2017;8:2759-2765 pubmed publisher
  • western blot knockout validation; mouse; fig 1
Hu X, Jogasuria A, Wang J, Kim C, Han Y, Shen H, et al. MitoNEET Deficiency Alleviates Experimental Alcoholic Steatohepatitis in Mice by Stimulating Endocrine Adiponectin-Fgf15 Axis. J Biol Chem. 2016;291:22482-22495 pubmed
Ordureau A, Paulo J, Zhang J, An H, Swatek K, Cannon J, et al. Global Landscape and Dynamics of Parkin and USP30-Dependent Ubiquitylomes in iNeurons during Mitophagic Signaling. Mol Cell. 2020;77:1124-1142.e10 pubmed publisher
Heo J, Harper N, Paulo J, Li M, Xu Q, Coughlin M, et al. Integrated proteogenetic analysis reveals the landscape of a mitochondrial-autophagosome synapse during PARK2-dependent mitophagy. Sci Adv. 2019;5:eaay4624 pubmed publisher
Koyano F, Yamano K, Kosako H, Kimura Y, Kimura M, Fujiki Y, et al. Parkin-mediated ubiquitylation redistributes MITOL/March5 from mitochondria to peroxisomes. EMBO Rep. 2019;20:e47728 pubmed publisher
Koyano F, Yamano K, Kosako H, Tanaka K, Matsuda N. Parkin recruitment to impaired mitochondria for nonselective ubiquitylation is facilitated by MITOL. J Biol Chem. 2019;: pubmed publisher
Heo J, Ordureau A, Swarup S, Paulo J, Shen K, Sabatini D, et al. RAB7A phosphorylation by TBK1 promotes mitophagy via the PINK-PARKIN pathway. Sci Adv. 2018;4:eaav0443 pubmed publisher
McWilliams T, Barini E, Pohjolan Pirhonen R, Brooks S, Singh F, Burel S, et al. Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol. 2018;8: pubmed publisher
Meram A, Chen J, Patel S, Kim D, Shirley B, Covello P, et al. Hydrogen Sulfide Is Increased in Oral Squamous Cell Carcinoma Compared to Adjacent Benign Oral Mucosae. Anticancer Res. 2018;38:3843-3852 pubmed publisher
Ordureau A, Paulo J, Zhang W, Ahfeldt T, Zhang J, Cohn E, et al. Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics. Mol Cell. 2018;70:211-227.e8 pubmed publisher
McWilliams T, Prescott A, Montava Garriga L, Ball G, Singh F, Barini E, et al. Basal Mitophagy Occurs Independently of PINK1 in Mouse Tissues of High Metabolic Demand. Cell Metab. 2018;27:439-449.e5 pubmed publisher
Gersch M, Gladkova C, Schubert A, Michel M, Maslen S, Komander D. Mechanism and regulation of the Lys6-selective deubiquitinase USP30. Nat Struct Mol Biol. 2017;24:920-930 pubmed publisher
Heritage M, Jaskowski L, Bridle K, Campbell C, Briskey D, Britton L, et al. Combination curcumin and vitamin E treatment attenuates diet-induced steatosis in Hfe-/- mice. World J Gastrointest Pathophysiol. 2017;8:67-76 pubmed publisher
Ko Y, Domingo Vidal M, Roche M, Lin Z, Whitaker Menezes D, Seifert E, et al. TP53-inducible Glycolysis and Apoptosis Regulator (TIGAR) Metabolically Reprograms Carcinoma and Stromal Cells in Breast Cancer. J Biol Chem. 2016;291:26291-26303 pubmed
Lai Y, Kondapalli C, Lehneck R, Procter J, Dill B, Woodroof H, et al. Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. EMBO J. 2015;34:2840-61 pubmed publisher
Kazlauskaite A, Martínez Torres R, Wilkie S, Kumar A, Peltier J, González A, et al. Binding to serine 65-phosphorylated ubiquitin primes Parkin for optimal PINK1-dependent phosphorylation and activation. EMBO Rep. 2015;16:939-54 pubmed publisher
Ordureau A, Heo J, Duda D, Paulo J, Olszewski J, Yanishevski D, et al. Defining roles of PARKIN and ubiquitin phosphorylation by PINK1 in mitochondrial quality control using a ubiquitin replacement strategy. Proc Natl Acad Sci U S A. 2015;112:6637-42 pubmed publisher
Shabalina I, Landreh L, Edgar D, Hou M, Gibanova N, Atanassova N, et al. Leydig cell steroidogenesis unexpectedly escapes mitochondrial dysfunction in prematurely aging mice. FASEB J. 2015;29:3274-86 pubmed publisher
product information
CatalogNo :
16006-1-AP
AntigenName :
CISD1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
CDGSH iron sulfur domain 1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
C10orf70, CDGSH iron sulfur domain 1, CISD1, MDS029, mitoNEET, Mnt, ZCD1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC007043
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
FC 1:0 ; IF 1:25 ; IHC 1:100 ; IP 1:2000 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.