This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ISG15
catalog :
15981-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 15
Reference
Min Y, Ning Y, Wang H, Deng F. A RIG-I-like receptor directs antiviral responses to a bunyavirus and is antagonized by virus-induced blockade of TRIM25-mediated ubiquitination. J Biol Chem. 2020;295:9691-9711 pubmed publisher
Dzimianski J, Scholte F, Williams I, Langley C, Freitas B, Spengler J, et al. Determining the molecular drivers of species-specific interferon-stimulated gene product 15 interactions with nairovirus ovarian tumor domain proteases. PLoS ONE. 2019;14:e0226415 pubmed publisher
Bianco C, Mohr I. Ribosome biogenesis restricts innate immune responses to virus infection and DNA. elife. 2019;8: pubmed publisher
Osei Kuffour E, König R, Haussinger D, Schulz W, Munk C. ISG15 Deficiency Enhances HIV-1 Infection by Accumulating Misfolded p53. MBio. 2019;10: pubmed publisher
McFarlane S, Orr A, Roberts A, Conn K, Iliev V, Loney C, et al. The histone chaperone HIRA promotes the induction of host innate immune defences in response to HSV-1 infection. PLoS Pathog. 2019;15:e1007667 pubmed publisher
Yao Z, Jia X, Megger D, Chen J, Liu Y, Li J, et al. Label-Free Proteomic Analysis of Exosomes Secreted from THP-1-Derived Macrophages Treated with IFN-α Identifies Antiviral Proteins Enriched in Exosomes. J Proteome Res. 2019;18:855-864 pubmed publisher
Li Y, Bai W, Zhang L. The Overexpression of CD80 and ISG15 Are Associated with the Progression and Metastasis of Breast Cancer by a Meta-Analysis Integrating Three Microarray Datasets. Pathol Oncol Res. 2018;: pubmed publisher
Welch S, Scholte F, Albarino C, Kainulainen M, Coleman McCray J, Guerrero L, et al. The S Genome Segment Is Sufficient to Maintain Pathogenicity in Intra-Clade Lassa Virus Reassortants in a Guinea Pig Model. Front Cell Infect Microbiol. 2018;8:240 pubmed publisher
Yuan H, Zhou W, Yang Y, Xue L, Liu L, Song Y. ISG15 promotes esophageal squamous cell carcinoma tumorigenesis via c-MET/Fyn/β-catenin signaling pathway. Exp Cell Res. 2018;367:47-55 pubmed publisher
Alandijany T, Roberts A, Conn K, Loney C, McFarlane S, Orr A, et al. Distinct temporal roles for the promyelocytic leukaemia (PML) protein in the sequential regulation of intracellular host immunity to HSV-1 infection. PLoS Pathog. 2018;14:e1006769 pubmed publisher
Chauche C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza A, Gu Q, et al. Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1. J Virol. 2018;92: pubmed publisher
Bianco C, Mohr I. Restriction of Human Cytomegalovirus Replication by ISG15, a Host Effector Regulated by cGAS-STING Double-Stranded-DNA Sensing. J Virol. 2017;91: pubmed publisher
Villarroya Beltri C, Baixauli F, Mittelbrunn M, Fernandez Delgado I, Torralba D, Moreno Gonzalo O, et al. ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins. Nat Commun. 2016;7:13588 pubmed publisher
Care M, Stephenson S, Barnes N, Fan I, Zougman A, El Sherbiny Y, et al. Network Analysis Identifies Proinflammatory Plasma Cell Polarization for Secretion of ISG15 in Human Autoimmunity. J Immunol. 2016;197:1447-59 pubmed publisher
Zeng X, Wang S, Chi X, Chen S, Huang S, Lin Q, et al. Infection of goats with goatpox virus triggers host antiviral defense through activation of innate immune signaling. Res Vet Sci. 2016;104:40-9 pubmed publisher
product information
CatalogNo :
15981-1-AP
AntigenName :
ISG15
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
ISG15 ubiquitin-like modifier
Immunogen :
Recombinant Protein
Species :
goat, human
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
G1P2, hUCRP, IFI15, IP17, ISG15, ISG15 ubiquitin like modifier, Ubiquitin like protein ISG15, UCRP
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC009507
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IF 1:50 ; IHC 1:50 ; IP 1:500 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.