This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
BHMT
catalog :
15965-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunoprecipitation
citations: 20
Reference
Omer N, Hu Y, Idriss A, Abobaker H, Hou Z, Yang S, et al. Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes. Poult Sci. 2020;99:3121-3132 pubmed publisher
Hu Y, Feng Y, Ding Z, Lv L, Sui Y, Sun Q, et al. Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes. Poult Sci. 2020;99:3111-3120 pubmed publisher
Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, et al. Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion. J Proteome Res. 2019;18:2032-2044 pubmed publisher
Jia L, Zeng Y, Hu Y, Liu J, Yin C, Niu Y, et al. Homocysteine impairs porcine oocyte quality via deregulation of one-carbon metabolism and hypermethylation of mitochondrial DNA†. Biol Reprod. 2019;100:907-916 pubmed publisher
Hu Y, Sun Q, Hu Y, Hou Z, Zong Y, Omer N, et al. Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation. J Nutr. 2018;148:316-325 pubmed publisher
Hou Z, Sun Q, Hu Y, Yang S, Zong Y, Zhao R. Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications. Comp Biochem Physiol B Biochem Mol Biol. 2018;218:30-36 pubmed publisher
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R. Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams. J Agric Food Chem. 2018;66:2704-2713 pubmed publisher
Omer N, Hu Y, Hu Y, Idriss A, Abobaker H, Hou Z, et al. Dietary betaine activates hepatic VTGII expression in laying hens associated with hypomethylation of GR gene promoter and enhanced GR expression. J Anim Sci Biotechnol. 2018;9:2 pubmed publisher
Zhao N, Yang S, Jia Y, Sun B, He B, Zhao R. Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats. J Nutr Biochem. 2018;54:105-112 pubmed publisher
Idriss A, Hu Y, Hou Z, Hu Y, Sun Q, Omer N, et al. Dietary betaine supplementation in hens modulates hypothalamic expression of cholesterol metabolic genes in F1 cockerels through modification of DNA methylation. Comp Biochem Physiol B Biochem Mol Biol. 2018;217:14-20 pubmed publisher
Zhao N, Yang S, Hu Y, Dong H, Zhao R. Maternal betaine supplementation in rats induces intergenerational changes in hepatic IGF-1 expression and DNA methylation. Mol Nutr Food Res. 2017;61: pubmed publisher
Idriss A, Hu Y, Sun Q, Jia L, Jia Y, Omer N, et al. Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation. Poult Sci. 2017;96:1715-1724 pubmed publisher
Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, et al. Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification. Nutrients. 2016;8: pubmed
Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R. Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets. J Agric Food Chem. 2016;64:7530-7539 pubmed
Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, et al. Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway. Int J Biochem Cell Biol. 2016;79:222-230 pubmed publisher
Qin S, Zhou Y, Gray L, Kusebauch U, McEvoy L, Antoine D, et al. Identification of Organ-Enriched Protein Biomarkers of Acute Liver Injury by Targeted Quantitative Proteomics of Blood in Acetaminophen- and Carbon-Tetrachloride-Treated Mouse Models and Acetaminophen Overdose Patients. J Proteome Res. 2016;15:3724-3740 pubmed
Jia L, Li J, He B, Jia Y, Niu Y, Wang C, et al. Abnormally activated one-carbon metabolic pathway is associated with mtDNA hypermethylation and mitochondrial malfunction in the oocytes of polycystic gilt ovaries. Sci Rep. 2016;6:19436 pubmed publisher
Jia Y, Song H, Gao G, Cai D, Yang X, Zhao R. Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets. J Agric Food Chem. 2015;63:10152-60 pubmed publisher
Hu Y, Sun Q, Li X, Wang M, Cai D, Li X, et al. In Ovo injection of betaine affects hepatic cholesterol metabolism through epigenetic gene regulation in newly hatched chicks. PLoS ONE. 2015;10:e0122643 pubmed publisher
Li X, Sun Q, Li X, Cai D, Sui S, Jia Y, et al. Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions. Eur J Nutr. 2015;54:1201-10 pubmed publisher
product information
CatalogNo :
15965-1-AP
AntigenName :
BHMT
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
betaine-homocysteine methyltransferase
Immunogen :
Recombinant Protein
Species :
chicken, gilt, human, landrace, mouse, pig, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
BHMT
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC012616
Category :
Binding Proteins;Metabolism;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IHC 1:100 ; IP 1:1000 ; WB 1:4000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.