This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
ALDH1A1
catalog :
15910-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 43
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:1000; loading ...; fig 4f
Gao L, Sang J, Cao H. Limonin enhances the radiosensitivity of nasopharyngeal carcinoma cells via attenuating Stat3-induced cell stemness. Biomed Pharmacother. 2019;118:109366 pubmed publisher
  • western blot; human; loading ...; fig 1c
Li E, Zhang T, Sun X, Li Y, Geng H, Yu D, et al. Sonic hedgehog pathway mediates genistein inhibition of renal cancer stem cells. Oncol Lett. 2019;18:3081-3091 pubmed publisher
  • immunocytochemistry; human; loading ...; fig 3i
  • western blot; human; loading ...; fig 2f
Xie C, Zhu J, Jiang Y, Chen J, Wang X, Geng S, et al. Sulforaphane Inhibits the Acquisition of Tobacco Smoke-Induced Lung Cancer Stem Cell-Like Properties via the IL-6/ΔNp63α/Notch Axis. Theranostics. 2019;9:4827-4840 pubmed publisher
Sun H, Zhang T, Liu R, Cao W, Zhang Z, Liu Z, et al. Resveratrol Inhibition of Renal Cancer Stem Cell Characteristics and Modulation of the Sonic Hedgehog Pathway. Nutr Cancer. 2020;:1-11 pubmed publisher
Wakabayashi Y, Tamura Y, Kouzaki K, Kikuchi N, Hiranuma K, Menuki K, et al. Acetaldehyde dehydrogenase 2 deficiency increases mitochondrial reactive oxygen species emission and induces mitochondrial protease Omi/HtrA2 in skeletal muscle. Am J Physiol Regul Integr Comp Physiol. 2020;318:R677-R690 pubmed publisher
Chen Y, Shao Z, Jiang E, Zhou X, Wang L, Wang H, et al. CCL21/CCR7 interaction promotes EMT and enhances the stemness of OSCC via a JAK2/STAT3 signaling pathway. J Cell Physiol. 2020;235:5995-6009 pubmed publisher
Cheng Y, Li L, Pan S, Jiang H, Jin H. Targeting Frizzled-7 Decreases Stemness and Chemotherapeutic Resistance in Gastric Cancer Cells by Suppressing Myc Expression. Med Sci Monit. 2019;25:8637-8644 pubmed publisher
Jia Y, Jiang J, Zhao K, Zhang T, Sun P, Peng J, et al. Disulfiram suppressed ethanol promoted RANKL-induced osteoclastogenesis in vitro and ethanol-induced osteoporosis in vivo via ALDH1A1-NFATc1 axis. Aging (Albany NY). 2019;11:8103-8119 pubmed publisher
Zhang Q, Cao W, Wang X, Zhang M, Lu X, Chen J, et al. Genistein inhibits nasopharyngeal cancer stem cells through sonic hedgehog signaling. Phytother Res. 2019;: pubmed publisher
Zhu R, Gires O, Zhu L, Liu J, Li J, Yang H, et al. TSPAN8 promotes cancer cell stemness via activation of sonic Hedgehog signaling. Nat Commun. 2019;10:2863 pubmed publisher
Li X, Zheng L, Xi T. WITHDRAWN: Tanshinone IIA-mediated inhibition on miR-125b/STARD13 axis attenuates the stemness and enhances adriamycin sensitivity of breast cancer cells. Biochimie. 2019;: pubmed publisher
Wu H, He Y, Chen H, Liu Y, Wei B, Chen G, et al. LncRNA THOR increases osteosarcoma cell stemness and migration by enhancing SOX9 mRNA stability. FEBS Open Bio. 2019;9:781-790 pubmed publisher
Zhang L, Chen Y, Li C, Liu J, Ren H, Li L, et al. RNA binding protein PUM2 promotes the stemness of breast cancer cells via competitively binding to neuropilin-1 (NRP-1) mRNA with miR-376a. Biomed Pharmacother. 2019;114:108772 pubmed publisher
Chen J, Wang P, Cai R, Peng H, Zhang C, Zhang M. SLC34A2 promotes neuroblastoma cell stemness via enhancement of miR-25/Gsk3β-mediated activation of Wnt/β-catenin signaling. FEBS Open Bio. 2019;9:527-537 pubmed publisher
Huang R, Nie W, Yao K, Chou J. Depletion of the lncRNA RP11-567G11.1 inhibits pancreatic cancer progression. Biomed Pharmacother. 2019;112:108685 pubmed publisher
Wang D, Zheng J, Liu X, Xue Y, Liu L, Ma J, et al. Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis. Mol Ther Nucleic Acids. 2019;14:465-482 pubmed publisher
Ge M, Zhang L, Cao L, Xie C, Li X, Li Y, et al. Sulforaphane inhibits gastric cancer stem cells via suppressing sonic hedgehog pathway. Int J Food Sci Nutr. 2019;70:570-578 pubmed publisher
Lai Y, Yu W, Kuo S, Ho C, Hung C, Way T, et al. CSC-3436 inhibits TWIST-induced epithelial-mesenchymal transition via the suppression of Twist/Bmi1/Akt pathway in head and neck squamous cell carcinoma. J Cell Physiol. 2019;234:9118-9129 pubmed publisher
Qin T, Li B, Feng X, Fan S, Liu L, Liu D, et al. Abnormally elevated USP37 expression in breast cancer stem cells regulates stemness, epithelial-mesenchymal transition and cisplatin sensitivity. J Exp Clin Cancer Res. 2018;37:287 pubmed publisher
Li Z, Liu H, Zhong Q, Wu J, Tang Z. LncRNA UCA1 is necessary for TGF-β-induced epithelial-mesenchymal transition and stemness via acting as a ceRNA for Slug in glioma cells. FEBS Open Bio. 2018;8:1855-1865 pubmed publisher
Liu L, Wang Q, Mao J, Qin T, Sun Y, Yang J, et al. Salinomycin suppresses cancer cell stemness and attenuates TGF-β-induced epithelial-mesenchymal transition of renal cell carcinoma cells. Chem Biol Interact. 2018;296:145-153 pubmed publisher
Tan F, Huang Y, Pei Q, Liu H, Pei H, Zhu H. Matrix stiffness mediates stemness characteristics via activating the Yes-associated protein in colorectal cancer cells. J Cell Biochem. 2018;: pubmed publisher
Chen Y, Li Y, Wang X, Meng Y, Zhang Q, Zhu J, et al. Phenethyl isothiocyanate inhibits colorectal cancer stem cells by suppressing Wnt/β-catenin pathway. Phytother Res. 2018;32:2447-2455 pubmed publisher
Wang B, Xi C, Liu M, Sun H, Liu S, Song L, et al. Breast fibroblasts in both cancer and normal tissues induce phenotypic transformation of breast cancer stem cells: a preliminary study. Peerj. 2018;6:e4805 pubmed publisher
Li J, Huang C, Li J, Yuan J, Chen Q, Zhang W, et al. Six2 is negatively correlated with good prognosis and decreases 5-FU sensitivity via suppressing E-cadherin expression in hepatocellular carcinoma cells. Biomed Pharmacother. 2018;104:204-210 pubmed publisher
Wang J, Chen J, Jiang Y, Shi Y, Zhu J, Xie C, et al. Wnt/?-catenin modulates chronic tobacco smoke exposure-induced acquisition of pulmonary cancer stem cell properties and diallyl trisulfide intervention. Toxicol Lett. 2018;291:70-76 pubmed publisher
Zhang Q, Li X, Chen Y, Chen J, Zhu J, Meng Y, et al. Wnt/β-catenin signaling mediates the suppressive effects of diallyl trisulfide on colorectal cancer stem cells. Cancer Chemother Pharmacol. 2018;81:969-977 pubmed publisher
Li X, Meng Y, Xie C, Zhu J, Wang X, Li Y, et al. Diallyl Trisulfide inhibits breast cancer stem cells via suppression of Wnt/β-catenin pathway. J Cell Biochem. 2018;119:4134-4141 pubmed publisher
Xu X, Li C, Gao X, Xia K, Guo H, Li Y, et al. Excessive UBE3A dosage impairs retinoic acid signaling and synaptic plasticity in autism spectrum disorders. Cell Res. 2018;28:48-68 pubmed publisher
Yu X, Zhang F, Mao J, Lu Y, Li J, Ma W, et al. Protein tyrosine phosphatase receptor-type ? acts as a negative regulator suppressing breast cancer. Oncotarget. 2017;8:98798-98811 pubmed publisher
Zhang Q, Zhuang J, Deng Y, Yang L, Cao W, Chen W, et al. miR34a/GOLPH3 Axis abrogates Urothelial Bladder Cancer Chemoresistance via Reduced Cancer Stemness. Theranostics. 2017;7:4777-4790 pubmed publisher
Wang D, Kong X, Li Y, Qian W, Ma J, Wang D, et al. Curcumin inhibits bladder cancer stem cells by suppressing Sonic Hedgehog pathway. Biochem Biophys Res Commun. 2017;493:521-527 pubmed publisher
Li B, Lu Y, Yu L, Han X, Wang H, Mao J, et al. miR-221/222 promote cancer stem-like cell properties and tumor growth of breast cancer via targeting PTEN and sustained Akt/NF-?B/COX-2 activation. Chem Biol Interact. 2017;277:33-42 pubmed publisher
Zhu J, Wang S, Chen Y, Li X, Jiang Y, Yang X, et al. miR-19 targeting of GSK3β mediates sulforaphane suppression of lung cancer stem cells. J Nutr Biochem. 2017;44:80-91 pubmed publisher
Zhu J, Yang X, Chen Y, Jiang Y, Wang S, Li Y, et al. Curcumin Suppresses Lung Cancer Stem Cells via Inhibiting Wnt/?-catenin and Sonic Hedgehog Pathways. Phytother Res. 2017;31:680-688 pubmed publisher
Zhu J, Jiang Y, Yang X, Wang S, Xie C, Li X, et al. Wnt/?-catenin pathway mediates (-)-Epigallocatechin-3-gallate (EGCG) inhibition of lung cancer stem cells. Biochem Biophys Res Commun. 2017;482:15-21 pubmed publisher
Zhu Y, Cai L, Guo J, Chen N, Yi X, Zhao Y, et al. Depletion of Dicer promotes epithelial ovarian cancer progression by elevating PDIA3 expression. Tumour Biol. 2016;37:14009-14023 pubmed
Liu Y, Lu R, Gu J, Chen Y, Zhang X, Zhang L, et al. Aldehyde dehydrogenase 1A1 up-regulates stem cell markers in benzo[a]pyrene-induced malignant transformation of BEAS-2B cells. Environ Toxicol Pharmacol. 2016;45:241-50 pubmed publisher
Zheng Z, Xu H, Suo S, Xu X, Ni M, Gu L, et al. The Essential Role of H19 Contributing to Cisplatin Resistance by Regulating Glutathione Metabolism in High-Grade Serous Ovarian Cancer. Sci Rep. 2016;6:26093 pubmed publisher
Zhao Z, Zhang L, Huang C, Ma S, Bu L, Liu J, et al. NOTCH1 inhibition enhances the efficacy of conventional chemotherapeutic agents by targeting head neck cancer stem cell. Sci Rep. 2016;6:24704 pubmed publisher
Kawai T, Yanaka N, Richards J, Shimada M. De Novo-Synthesized Retinoic Acid in Ovarian Antral Follicles Enhances FSH-Mediated Ovarian Follicular Cell Differentiation and Female Fertility. Endocrinology. 2016;157:2160-72 pubmed publisher
Ma S, Wang W, Huang C, Zhang W, Sun Z. Anterior gradient protein 2 expression in high grade head and neck squamous cell carcinoma correlated with cancer stem cell and epithelial mesenchymal transition. Oncotarget. 2015;6:8807-21 pubmed
He K, Zhang L, Huang C, Ma S, Wang Y, Wang W, et al. CD163+ tumor-associated macrophages correlated with poor prognosis and cancer stem cells in oral squamous cell carcinoma. Biomed Res Int. 2014;2014:838632 pubmed publisher
product information
CatalogNo :
15910-1-AP
AntigenName :
ALDH1A1
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
aldehyde dehydrogenase 1 family, member A1
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ALDC, ALDH E1, ALDH1, ALDH11, ALDH1A1, ALHDII, PUMB1, RALDH 1, RALDH1, Retinal dehydrogenase 1
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC001505
Category :
Metabolism;Neurology;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:150 ; IHC 1:200 ; IP 1:500 ; WB 1:2000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.