This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
INS
catalog :
15848-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
immunohistochemistry, immunocytochemistry
citations: 19
Reference
Yao X, Li K, Liang C, Zhou Z, Wang J, Wang S, et al. Tectorigenin enhances PDX1 expression and protects pancreatic β-cells by activating ERK and reducing ER stress. J Biol Chem. 2020;295:12975-12992 pubmed publisher
Lv W, Graves D, He L, Shi Y, Deng X, Zhao Y, et al. Depletion of the diabetic gut microbiota resistance enhances stem cells therapy in type 1 diabetes mellitus. Theranostics. 2020;10:6500-6516 pubmed publisher
Yao Q, Huang Z, Zhai Y, Yue M, Luo L, Xue P, et al. Localized Controlled Release of Bilirubin from β-Cyclodextrin-Conjugated ε-Polylysine To Attenuate Oxidative Stress and Inflammation in Transplanted Islets. ACS Appl Mater Interfaces. 2020;12:5462-5475 pubmed publisher
Pavlikova N, Daniel P, Srámek J, Jelinek M, Šrámková V, Němcová V, et al. Upregulation of vitamin D-binding protein is associated with changes in insulin production in pancreatic beta-cells exposed to p,p'-DDT and p,p'-DDE. Sci Rep. 2019;9:18026 pubmed publisher
Wu M, Chen W, Zhang S, Huang S, Zhang A, Zhang Y, et al. Rotenone protects against β-cell apoptosis and attenuates type 1 diabetes mellitus. Apoptosis. 2019;24:879-891 pubmed publisher
Qi W, Yang X, Ye N, Li S, Han Q, Huang J, et al. TLR4 gene in the regulation of periodontitis and its molecular mechanism. Exp Ther Med. 2019;18:1961-1966 pubmed publisher
Han F, Li X, Yang J, Liu H, Zhang Y, Yang X, et al. Salsalate Prevents β-Cell Dedifferentiation in OLETF Rats with Type 2 Diabetes through Notch1 Pathway. Aging Dis. 2019;10:719-730 pubmed publisher
Wang Q, Zhao C, Jin L, Zhang H, Miao Q, Liu H, et al. AWRK6, a Novel GLP-1 Receptor Agonist, Attenuates Diabetes by Stimulating Insulin Secretion. Int J Mol Sci. 2018;19: pubmed publisher
Ji R, Zhu J, Wang D, Sui Q, Knight G, Burnstock G, et al. Expression of P2X1 receptors in somatostatin-containing cells in mouse gastrointestinal tract and pancreatic islets of both mouse and human. Purinergic Signal. 2018;14:285-298 pubmed publisher
Luo Y, Xu Y, Wang Z, Li X, Xing W, Zhang T. The Synergy of Two Factors on Insulin Expression. Cell Reprogram. 2018;20:49-54 pubmed publisher
Li H, Wang Z, Li Y, Fang R, Wang H, Shi H, et al. Hepatitis B X-interacting protein promotes the formation of the insulin gene-transcribing protein complex Pdx-1/Neurod1 in animal pancreatic β-cells. J Biol Chem. 2018;293:2053-2065 pubmed publisher
Zhang L, Song Q, Jin J, Huang P, Wang Z, Xie X, et al. Differential protein analysis of serum exosomes post-intravenous immunoglobulin therapy in patients with Kawasaki disease. Cardiol Young. 2017;27:1786-1796 pubmed publisher
Wang T, Xie C, Yu P, Fang F, Zhu J, Cheng J, et al. Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity. Sci Rep. 2017;7:7497 pubmed publisher
Mao R, Wu D, Hu S, Zhou K, Wang M, Wang Y. Secretory expression and surface display of a new and biologically active single-chain insulin (SCI-59) analog by lactic acid bacteria. Appl Microbiol Biotechnol. 2017;101:3259-3271 pubmed publisher
Guo W, Gong Y, Fu Z, Fu J, Sun Y, Ju X, et al. The effect of cholesteryl ester transfer protein on pancreatic beta cell dysfunction in mice. Nutr Metab (Lond). 2016;13:21 pubmed publisher
Fang F, Gao Y, Wang T, Chen D, Liu J, Qian W, et al. Insulin signaling disruption in male mice due to perinatal bisphenol A exposure: Role of insulin signaling in the brain. Toxicol Lett. 2016;245:59-67 pubmed publisher
Karki A, Humphrey S, Steele R, Hess D, Taparowsky E, Konieczny S. Silencing Mist1 Gene Expression Is Essential for Recovery from Acute Pancreatitis. PLoS ONE. 2015;10:e0145724 pubmed publisher
Fang F, Chen D, Yu P, Qian W, Zhou J, Liu J, et al. Effects of Bisphenol A on glucose homeostasis and brain insulin signaling pathways in male mice. Gen Comp Endocrinol. 2015;212:44-50 pubmed publisher
Zheng H, Fu J, Xue P, Zhao R, Dong J, Liu D, et al. CNC-bZIP protein Nrf1-dependent regulation of glucose-stimulated insulin secretion. Antioxid Redox Signal. 2015;22:819-31 pubmed publisher
product information
CatalogNo :
15848-1-AP
AntigenName :
INS
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
INS
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
ILPR, INS, IRDN
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC005255
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Growth Factor/Cytokine/Hormone;Metabolism;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
AppTiter :
IF 1:100 ; IHC 1:500 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.