This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
IKBKB
catalog :
15649-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 28
Published Application/Species/Sample/DilutionReference
  • western blot; human; 1:500; fig 4
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed publisher
Wang Q, Tang Q, Zhao L, Zhang Q, Wu Y, Hu H, et al. Time serial transcriptome reveals Cyp2c29 as a key gene in hepatocellular carcinoma development. Cancer Biol Med. 2020;17:401-417 pubmed publisher
Dong X, Wu D, Zhang Y, Jia L, Pan X, Sun J, et al. Cathelicidin Modulates Vascular Smooth Muscle Cell Phenotypic Switching through ROS/IL-6 Pathway. Antioxidants (Basel). 2020;9: pubmed publisher
Kang N, Cao S, Jiang B, Zhang Q, Donkor P, Zhu Y, et al. Cetuximab enhances oridonin-induced apoptosis through mitochondrial pathway and endoplasmic reticulum stress in laryngeal squamous cell carcinoma cells. Toxicol In Vitro. 2020;67:104885 pubmed publisher
Almoiliqy M, Wen J, Xu B, Sun Y, Lian M, Li Y, et al. Cinnamaldehyde protects against rat intestinal ischemia/reperfusion injuries by synergistic inhibition of NF-κB and p53. Acta Pharmacol Sin. 2020;41:1208-1222 pubmed publisher
Lu S, Chang J, Huang C, Chen L. Therapeutic potential of proteasome inhibitors for dihydropyridine-induced gingival overgrowth. Oral Dis. 2019;: pubmed publisher
Wu M, Li P, An Y, Ren J, Yan D, Cui J, et al. Phloretin ameliorates dextran sulfate sodium-induced ulcerative colitis in mice by regulating the gut microbiota. Pharmacol Res. 2019;150:104489 pubmed publisher
Zhang L, Wang F, Zhang Q, Liang Q, Wang S, Xian M, et al. Anti-Inflammatory and Anti-Apoptotic Effects of Stybenpropol A on Human Umbilical Vein Endothelial Cells. Int J Mol Sci. 2019;20: pubmed publisher
Silva P, Nieva G, Igaz L. Suppression of Conditional TDP-43 Transgene Expression Differentially Affects Early Cognitive and Social Phenotypes in TDP-43 Mice. Front Genet. 2019;10:369 pubmed publisher
Reho J, Guo D, Rahmouni K. Mechanistic Target of Rapamycin Complex 1 Signaling Modulates Vascular Endothelial Function Through Reactive Oxygen Species. J Am Heart Assoc. 2019;8:e010662 pubmed publisher
Jia Y, Peng Y, Zhao Y, Cheng X, Zhou Y, Chai C, et al. Comparison of the Hepatoprotective Effects of the Three Main Stilbenes from Mulberry Twigs. J Agric Food Chem. 2019;: pubmed publisher
Sun S, Li F, Liu Y, Qu H, Wong S, Zeng L, et al. A novel inhibitor of nuclear factor kappa-B kinase subunit gamma mutation identified in an incontinentia pigmenti patient with syndromic tooth agenesis. Arch Oral Biol. 2019;101:100-107 pubmed publisher
Dong X, Zheng Z, Lin P, Fu X, Li F, Jiang J, et al. ACPAs promote IL-1β production in rheumatoid arthritis by activating the NLRP3 inflammasome. Cell Mol Immunol. 2019;: pubmed publisher
Shi H, Wang X, Quan H, Yan L, Pei X, Wang R, et al. Effects of Betaine on LPS-Stimulated Activation of Microglial M1/M2 Phenotypes by Suppressing TLR4/NF-κB Pathways in N9 Cells. Molecules. 2019;24: pubmed publisher
He Y, Xia Z, Yu D, Wang J, Jin L, Huang D, et al. Hepatoprotective effects and structure-activity relationship of five flavonoids against lipopolysaccharide/d-galactosamine induced acute liver failure in mice. Int Immunopharmacol. 2019;68:171-178 pubmed publisher
Li Y, Zhang J, Su L, Kellum J, Peng Z. Downregulation of TIMP2 attenuates sepsis-induced AKI through the NF-κb pathway. Biochim Biophys Acta Mol Basis Dis. 2019;1865:558-569 pubmed publisher
Hu H, Wang C, Jin Y, Meng Q, Liu Q, Liu Z, et al. Catalpol Inhibits Homocysteine-induced Oxidation and Inflammation via Inhibiting Nox4/NF-κB and GRP78/PERK Pathways in Human Aorta Endothelial Cells. Inflammation. 2019;42:64-80 pubmed publisher
Zhou Y, Hao C, Li C, Huang X, Li X, Tang Y, et al. Omentin-1 protects against bleomycin-induced acute lung injury. Mol Immunol. 2018;103:96-105 pubmed publisher
Ning C, Gao X, Wang C, Huo X, Liu Z, Sun H, et al. Protective effects of ginsenoside Rg1 against lipopolysaccharide/d-galactosamine-induced acute liver injury in mice through inhibiting toll-like receptor 4 signaling pathway. Int Immunopharmacol. 2018;61:266-276 pubmed publisher
Liu H, Ma S, Xia H, Lou H, Zhu F, Sun L. Anti-inflammatory activities and potential mechanisms of phenolic acids isolated from Salvia miltiorrhiza f. alba roots in THP-1 macrophages. J Ethnopharmacol. 2018;222:201-207 pubmed publisher
Wang Y, Liu Y, Zhai J, Duan W, Sun S, Cui H, et al. scAAV9-VEGF-165 inhibits neuroinflammatory responses and invasion of macrophages into the peripheral nervous system of ALS transgenic mice. Brain Res Bull. 2018;140:233-242 pubmed publisher
Li D, Wang X, Huang Q, Li S, Zhou Y, Li Z. Cardioprotection of CAPE-oNO2 against myocardial ischemia/reperfusion induced ROS generation via regulating the SIRT1/eNOS/NF-?B pathway in vivo and in vitro. Redox Biol. 2018;15:62-73 pubmed publisher
Li Y, Li L, Zhang G, Wang Y, Chen H, Kong R, et al. Crucial microRNAs and genes in metformin's anti-pancreatic cancer effect explored by microRNA-mRNA integrated analysis. Invest New Drugs. 2018;36:20-27 pubmed publisher
He L, Li H, Huang N, Zhou X, Tian J, Li T, et al. Alpha-ketoglutarate suppresses the NF-κB-mediated inflammatory pathway and enhances the PXR-regulated detoxification pathway. Oncotarget. 2017;8:102974-102988 pubmed publisher
Zuo T, Zhu M, Xu W, Wang Z, Song H. Iridoids with Genipin Stem Nucleus Inhibit Lipopolysaccharide-Induced Inflammation and Oxidative Stress by Blocking the NF-κB Pathway in Polycystic Ovary Syndrome. Cell Physiol Biochem. 2017;43:1855-1865 pubmed publisher
Han X, Li B, Ye X, Mulatibieke T, Wu J, Dai J, et al. Dopamine D2 receptor signalling controls inflammation in acute pancreatitis via a PP2A-dependent Akt/NF-?B signalling pathway. Br J Pharmacol. 2017;: pubmed publisher
Yang Y, Gong X, Huang L, Wang Z, Wan R, Zhang P, et al. Diosmetin exerts anti-oxidative, anti-inflammatory and anti-apoptotic effects to protect against endotoxin-induced acute hepatic failure in mice. Oncotarget. 2017;8:30723-30733 pubmed publisher
Li Z, Wang Y, Newton I, Zhang L, Ji P, Li Z. GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ. Cell Signal. 2015;27:1237-45 pubmed publisher
product information
CatalogNo :
15649-1-AP
AntigenName :
IKBKB
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase beta
Immunogen :
Recombinant Protein
Species :
human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
I kappa B kinase 2, I kappa B kinase beta, IKBKB, IKK B, IKK beta, IKK2, IKKB, IκB, NFKBIKB
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC006231
Category :
Binding Proteins;Disease Related;Immunology;Membrane Proteins;Metabolism;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:200 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.