This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
PPARA
catalog :
15540-1-AP
quantity :
150UL
price :
299 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human, mouse
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation
citations: 52
Published Application/Species/Sample/DilutionReference
  • western blot; mouse; loading ...; fig 3d, 7b
Yang S, Ma C, Wu H, Zhang H, Yuan F, Yang G, et al. Tectorigenin attenuates diabetic nephropathy by improving vascular endothelium dysfunction through activating AdipoR1/2 pathway. Pharmacol Res. 2020;153:104678 pubmed publisher
  • western blot; mouse; loading ...; fig 5a
Charrier A, Wang L, Stephenson E, Ghanta S, Ko C, Croniger C, et al. Zinc finger protein 407 overexpression upregulates PPAR target gene expression and improves glucose homeostasis in mice. Am J Physiol Endocrinol Metab. 2016;311:E869-E880 pubmed publisher
Cheng K, Yu C, Li Z, Li S, Yan E, Song Z, et al. Resveratrol improves meat quality, muscular antioxidant capacity, lipid metabolism and fiber type composition of intrauterine growth retarded pigs. Meat Sci. 2020;170:108237 pubmed publisher
Chen N, Mu L, Yang Z, Du C, Wu M, Song S, et al. Carbohydrate response element-binding protein regulates lipid metabolism via mTOR complex1 in diabetic nephropathy. J Cell Physiol. 2020;: pubmed publisher
Zhang Z, Zong C, Jiang M, Hu H, Cheng X, Ni J, et al. Hepatic HuR modulates lipid homeostasis in response to high-fat diet. Nat Commun. 2020;11:3067 pubmed publisher
Wang D, Zhu X, Tang X, Li H, Yizhen X, Chen D. Auxiliary antitumor effects of fungal proteins from Hericium erinaceus by target on the gut microbiota. J Food Sci. 2020;85:1872-1890 pubmed publisher
Chen K, Ma Z, Yan X, Liu J, Xu W, Li Y, et al. Investigation of the Lipid-Lowering Mechanisms and Active Ingredients of Danhe Granule on Hyperlipidemia Based on Systems Pharmacology. Front Pharmacol. 2020;11:528 pubmed publisher
Li L, Zheng W, Wang C, Qi J, Li H. Mogroside V Protects against Hepatic Steatosis in Mice on a High-Fat Diet and LO2 Cells Treated with Free Fatty Acids via AMPK Activation. Evid Based Complement Alternat Med. 2020;2020:7826874 pubmed publisher
Zhang Q, Ma X, Dong M, Tan J, Zhang J, Zhuang L, et al. MiR-30b-5p regulates the lipid metabolism by targeting PPARGC1A in Huh-7 cell line. Lipids Health Dis. 2020;19:76 pubmed publisher
Li M, Li C, Ye Z, Huang J, Li Y, Lai W, et al. Sirt3 modulates fatty acid oxidation and attenuates cisplatin-induced AKI in mice. J Cell Mol Med. 2020;24:5109-5121 pubmed publisher
Zhu R, Wei J, Liu H, Liu C, Wang L, Chen B, et al. Lycopene attenuates body weight gain through induction of browning via regulation of peroxisome proliferator-activated receptor γ in high-fat diet-induced obese mice. J Nutr Biochem. 2020;78:108335 pubmed publisher
Ling Y, Shi Z, Yang X, Cai Z, Wang L, Wu X, et al. Hypolipidemic effect of pure total flavonoids from peel of Citrus (PTFC) on hamsters of hyperlipidemia and its potential mechanism. Exp Gerontol. 2020;130:110786 pubmed publisher
Kao Y, Wei W, Tsai K, Wang L. High Fat Diet Suppresses Peroxisome Proliferator-Activated Receptors and Reduces Dopaminergic Neurons in the Substantia Nigra. Int J Mol Sci. 2019;21: pubmed publisher
Qin L, Chen J, Tang L, Zuo T, Chen H, Gao R, et al. Significant Role of Dicer and miR-223 in Adipose Tissue of Polycystic Ovary Syndrome Patients. Biomed Res Int. 2019;2019:9193236 pubmed publisher
Yang S, Chen Y, Duan Y, Ma C, Liu L, Li Q, et al. Therapeutic potential of NaoXinTong Capsule on the developed diabetic nephropathy in db/db mice. Biomed Pharmacother. 2019;118:109389 pubmed publisher
Lu T, Fan Z, Hou J, Qi X, Guo M, Ju J, et al. Loquat leaf polysaccharides improve glomerular injury in rats with anti-Thy 1 nephritis via peroxisome proliferator-activated receptor alpha pathway. Am J Transl Res. 2019;11:3531-3542 pubmed
Ding S, Huang J, Qiu H, Chen R, Zhang J, Huang B, et al. Effects of PPARs/20-HETE on the renal impairment under diabetic conditions. Exp Cell Res. 2019;: pubmed publisher
He W, Xu Y, Ren X, Xiang D, Lei K, Zhang C, et al. Vitamin E Ameliorates Lipid Metabolism in Mice with Nonalcoholic Fatty Liver Disease via Nrf2/CES1 Signaling Pathway. Dig Dis Sci. 2019;: pubmed publisher
Ding S, Qiu H, Huang J, Chen R, Zhang J, Huang B, et al. Activation of 20-HETE/PPARs involved in reno-therapeutic effect of naringenin on diabetic nephropathy. Chem Biol Interact. 2019;307:116-124 pubmed publisher
Shi Y, Zhang W, Cheng Y, Liu C, Chen S. Bromide alleviates fatty acid-induced lipid accumulation in mouse primary hepatocytes through the activation of PPARα signals. J Cell Mol Med. 2019;23:4464-4474 pubmed publisher
Hao Z, Zhang Z, Lu D, Ding B, Shu L, Zhang Q, et al. Organophosphorus Flame Retardants Impair Intracellular Lipid Metabolic Function in Human Hepatocellular Cells. Chem Res Toxicol. 2019;32:1250-1258 pubmed publisher
Yang S, Wei L, Xia R, Liu L, Chen Y, Zhang W, et al. Formononetin ameliorates cholestasis by regulating hepatic SIRT1 and PPARα. Biochem Biophys Res Commun. 2019;512:770-778 pubmed publisher
Zheng M, Li Y, Wang G, Jin J, Wang Y, Wang T, et al. Protective effect of cultured bear bile powder against dimethylnitrosamine-induced hepatic fibrosis in rats. Biomed Pharmacother. 2019;112:108701 pubmed publisher
Yang D, Hu C, Deng X, Bai Y, Cao H, Guo J, et al. Therapeutic Effect of Chitooligosaccharide Tablets on Lipids in High-Fat Diets Induced Hyperlipidemic Rats. Molecules. 2019;24: pubmed publisher
Chen K, Chen X, Xue H, Zhang P, Fang W, Chen X, et al. Coenzyme Q10 attenuates high-fat diet-induced non-alcoholic fatty liver disease through activation of the AMPK pathway. Food Funct. 2019;10:814-823 pubmed publisher
Ren L, Sun D, Zhou X, Yang Y, Huang X, Li Y, et al. Chronic treatment with the modified Longdan Xiegan Tang attenuates olanzapine-induced fatty liver in rats by regulating hepatic de novo lipogenesis and fatty acid beta-oxidation-associated gene expression mediated by SREBP-1c, PPAR-alpha and AMPK-alp. J Ethnopharmacol. 2019;232:176-187 pubmed publisher
Zhang J, Qiu H, Huang J, Ding S, Huang B, Zhou P, et al. EETs/PPARs activation together mediates the preventive effect of naringenin in high glucose-induced cardiomyocyte hypertrophy. Biomed Pharmacother. 2019;109:1498-1505 pubmed publisher
Huang S, Xu M, Wu H, Wan C, Wang H, Wu Q, et al. Isoquercitrin Attenuated Cardiac Dysfunction Via AMPKα-Dependent Pathways in LPS-Treated Mice. Mol Nutr Food Res. 2018;62:e1800955 pubmed publisher
Maldonado E, Fisher C, Mazzatti D, Barber A, Tindall M, Plant N, et al. Multi-scale, whole-system models of liver metabolic adaptation to fat and sugar in non-alcoholic fatty liver disease. NPJ Syst Biol Appl. 2018;4:33 pubmed publisher
Huang J, Wang Y, Ying C, Liu L, Lou Z. Effects of mulberry leaf on experimental hyperlipidemia rats induced by high-fat diet. Exp Ther Med. 2018;16:547-556 pubmed publisher
Xiao Y, Yan W, Lu Y, Zhou K, Cai W. Neurotensin contributes to pediatric intestinal failure-associated liver disease via regulating intestinal bile acids uptake. EBioMedicine. 2018;35:133-141 pubmed publisher
Jiang Y, Fu C, Liu G, Guo J, Su Z. Cholesterol-lowering effects and potential mechanisms of chitooligosaccharide capsules in hyperlipidemic rats. Food Nutr Res. 2018;62: pubmed publisher
Wang W, Chen K, Xia Y, Mo W, Wang F, Dai W, et al. The Hepatoprotection by Oleanolic Acid Preconditioning: Focusing on PPAR? Activation. PPAR Res. 2018;2018:3180396 pubmed publisher
Zhang J, Qiu H, Huang J, Ding S, Huang B, Wu Q, et al. Naringenin exhibits the protective effect on cardiac hypertrophy via EETs-PPARs activation in streptozocin-induced diabetic mice. Biochem Biophys Res Commun. 2018;502:55-61 pubmed publisher
Zhou Y, Du D, Liu S, Zhao M, Yuan Y, Li L, et al. Polyacetylene glycoside attenuates ischemic kidney injury by co-inhibiting inflammation, mitochondria dysfunction and lipotoxicity. Life Sci. 2018;204:55-64 pubmed publisher
Lu X, Liu T, Chen K, Xia Y, Dai W, Xu S, et al. Isorhamnetin: A hepatoprotective flavonoid inhibits apoptosis and autophagy via P38/PPAR-? pathway in mice. Biomed Pharmacother. 2018;103:800-811 pubmed publisher
Wang C, Li L, Liu S, Liao G, Li L, Chen Y, et al. GLP-1 receptor agonist ameliorates obesity-induced chronic kidney injury via restoring renal metabolism homeostasis. PLoS ONE. 2018;13:e0193473 pubmed publisher
Ma C, Zhang W, Yang X, Liu Y, Liu L, Feng K, et al. Functional interplay between liver X receptor and AMP-activated protein kinase α inhibits atherosclerosis in apolipoprotein E-deficient mice - a new anti-atherogenic strategy. Br J Pharmacol. 2018;175:1486-1503 pubmed publisher
Li L, Wang C, Yang H, Liu S, Lu Y, Fu P, et al. Metabolomics reveal mitochondrial and fatty acid metabolism disorders that contribute to the development of DKD in T2DM patients. Mol Biosyst. 2017;13:2392-2400 pubmed publisher
Hu J, Luo H, Jiang Y, Chen P. Dietary capsaicin and antibiotics act synergistically to reduce non-alcoholic fatty liver disease induced by high fat diet in mice. Oncotarget. 2017;8:38161-38175 pubmed publisher
Ning L, He A, Lu D, Li J, Qiao F, Li D, et al. Nutritional background changes the hypolipidemic effects of fenofibrate in Nile tilapia (Oreochromis niloticus). Sci Rep. 2017;7:41706 pubmed publisher
Chen Z, Luo J, Sun S, Cao D, Shi H, Loor J. miR-148a and miR-17-5p synergistically regulate milk TAG synthesis via PPARGC1A and PPARA in goat mammary epithelial cells. RNA Biol. 2017;14:326-338 pubmed publisher
Zhang W, Shen X, Zhang W, Chen H, Xu W, Wei W. The effects of di 2-ethyl hexyl phthalate (DEHP) on cellular lipid accumulation in HepG2 cells and its potential mechanisms in the molecular level. Toxicol Mech Methods. 2017;27:245-252 pubmed publisher
Ji J, Zeng X, Cao L, Zhang L, Zhao Z, Yang D, et al. PPARβ/δ activation protects against corticosterone-induced ER stress in astrocytes by inhibiting the CpG hypermethylation of microRNA-181a. Neuropharmacology. 2017;113:396-406 pubmed publisher
Yang W, She L, Yu K, Yan S, Zhang X, Tian X, et al. Jatrorrhizine hydrochloride attenuates hyperlipidemia in a high-fat diet-induced obesity mouse model. Mol Med Rep. 2016;14:3277-84 pubmed publisher
Han X, Li W, Huang D, Yang X. Polyphenols from hawthorn peels and fleshes differently mitigate dyslipidemia, inflammation and oxidative stress in association with modulation of liver injury in high fructose diet-fed mice. Chem Biol Interact. 2016;257:132-40 pubmed publisher
Ning L, He A, Li J, Lu D, Jiao J, Li L, et al. Mechanisms and metabolic regulation of PPAR? activation in Nile tilapia (Oreochromis niloticus). Biochim Biophys Acta. 2016;1861:1036-1048 pubmed publisher
Chen H, Zhang W, Rui B, Yang S, Xu W, Wei W. Di(2-ethylhexyl) phthalate exacerbates non-alcoholic fatty liver in rats and its potential mechanisms. Environ Toxicol Pharmacol. 2016;42:38-44 pubmed publisher
Ma J, Bai J. Protective effects of heparin on endothelial cells in sepsis. Int J Clin Exp Med. 2015;8:5547-52 pubmed
Wang D, Chen S, Liu M, Liu C. Maternal obesity disrupts circadian rhythms of clock and metabolic genes in the offspring heart and liver. Chronobiol Int. 2015;32:615-26 pubmed publisher
Liu M, Xu L, Yin L, Qi Y, Xu Y, Han X, et al. Potent effects of dioscin against obesity in mice. Sci Rep. 2015;5:7973 pubmed publisher
Cui M, Xiao Z, Wang Y, Zheng M, Song T, Cai X, et al. Long noncoding RNA HULC modulates abnormal lipid metabolism in hepatoma cells through an miR-9-mediated RXRA signaling pathway. Cancer Res. 2015;75:846-57 pubmed publisher
product information
CatalogNo :
15540-1-AP
AntigenName :
PPARA
Package :
150UL
Price :
299 USD
Exsists20ul :
20ul trial size available
FullName :
peroxisome proliferator-activated receptor alpha
Immunogen :
Recombinant Protein
Species :
goat, hamster, human, mouse, nile tilapias, rat, swine
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
hPPAR, NR1C1, PPAR, PPAR alpha, PPARA, PPARα
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC000052
Category :
Binding Proteins;Cell Cycle;Cytoskeleton/Scaffold Proteins;Development;Immunology;Metabolism;Neurology;Signal transduction;
PurifyMethod :
Antigen affinity purification
NewAb :
False
IsSellable :
True
Feature :
siRNA
AppTiter :
IHC 1:50 ; IP 1:300 ; WB 1:600 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.