This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
Proteintech Group
product type :
antibody
product name :
Connexin-43
catalog :
15386-1-AP
quantity :
150 ul
price :
299 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat, cow
application :
western blot, ELISA, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry, immunohistochemistry - paraffin section
citations: 26
Published Application/Species/Sample/DilutionReference
  • immunohistochemistry - paraffin section; mouse; fig 2
  • western blot; mouse; fig 5
Lin J, Xue A, Li L, Li B, Li Y, Shen Y, et al. MicroRNA-19b Downregulates Gap Junction Protein Alpha1 and Synergizes with MicroRNA-1 in Viral Myocarditis. Int J Mol Sci. 2016;17: pubmed publisher
Pakuła M, Witucka A, Uruski P, Radziemski A, Moszyński R, Szpurek D, et al. Senescence-related deterioration of intercellular junctions in the peritoneal mesothelium promotes the transmesothelial invasion of ovarian cancer cells. Sci Rep. 2019;9:7587 pubmed publisher
He J, Li H, Li B, Xie Q, Yan D, Wang X. Bone marrow mesenchymal stem cells overexpressing GATA-4 improve cardiac function following myocardial infarction. Perfusion. 2019;:267659119847442 pubmed publisher
Pettee K, Becker K, Alberts A, Reinard K, Schroeder J, Eisenmann K. Targeting the mDia Formin-Assembled Cytoskeleton Is an Effective Anti-Invasion Strategy in Adult High-Grade Glioma Patient-Derived Neurospheres. Cancers (Basel). 2019;11: pubmed publisher
Zhang H, Liu M, Zhang Y, Li X. Trimetazidine Attenuates Exhaustive Exercise-Induced Myocardial Injury in Rats via Regulation of the Nrf2/NF-κB Signaling Pathway. Front Pharmacol. 2019;10:175 pubmed publisher
Adegoke E, Adeniran S, Zeng Y, Wang X, Wang H, Wang C, et al. Pharmacological inhibition of TLR4/NF-κB with TLR4-IN-C34 attenuated microcystin-leucine arginine toxicity in bovine Sertoli cells. J Appl Toxicol. 2019;39:832-843 pubmed publisher
Li Y, Merkel C, Zeng X, Heier J, Cantrell P, Sun M, et al. The N-cadherin interactome in primary cardiomyocytes as defined using quantitative proximity proteomics. J Cell Sci. 2019;132: pubmed publisher
Bell C, Shakespeare T, Smith A, Murray S. Visualization of Annular Gap Junction Vesicle Processing: The Interplay Between Annular Gap Junctions and Mitochondria. Int J Mol Sci. 2018;20: pubmed publisher
Adegoke E, Xue W, Machebe N, Adeniran S, Hao W, Chen W, et al. Sodium Selenite inhibits mitophagy, downregulation and mislocalization of blood-testis barrier proteins of bovine Sertoli cell exposed to microcystin-leucine arginine (MC-LR) via TLR4/NF-kB and mitochondrial signaling pathways blockage. Ecotoxicol Environ Saf. 2018;166:165-175 pubmed publisher
Adegoke E, Wang C, Machebe N, Wang X, Wang H, Adeniran S, et al. Microcystin-leucine arginine (MC-LR) induced inflammatory response in bovine sertoli cell via TLR4/NF-kB signaling pathway. Environ Toxicol Pharmacol. 2018;63:115-126 pubmed publisher
Rodriguez J, Orbe J, Saenz Pipaon G, Abizanda G, Gebara N, Radulescu F, et al. Selective increase of cardiomyocyte derived extracellular vesicles after experimental myocardial infarction and functional effects on the endothelium. Thromb Res. 2018;170:1-9 pubmed publisher
Guo J, Mi X, Zhan R, Li M, Wei L, Sun J. Aquaporin 4 Silencing Aggravates Hydrocephalus Induced by Injection of Autologous Blood in Rats. Med Sci Monit. 2018;24:4204-4212 pubmed publisher
Zhang B, Li X, Chen C, Jiang W, Lu D, Liu Q, et al. Renal Denervation Effects on Myocardial Fibrosis and Ventricular Arrhythmias in Rats with Ischemic Cardiomyopathy. Cell Physiol Biochem. 2018;46:2471-2479 pubmed publisher
Li J, Wang S, Bai J, Yang X, Zhang Y, Che Y, et al. Novel Role for the Immunoproteasome Subunit PSMB10 in Angiotensin II-Induced Atrial Fibrillation in Mice. Hypertension. 2018;71:866-876 pubmed publisher
Liao J, Hong T, Xu J, Zeng E, Tang B, Lai W. Expression of Connexin43 in Cerebral Arteries of Patients with Moyamoya Disease. J Stroke Cerebrovasc Dis. 2018;27:1107-1114 pubmed publisher
Adegoke E, Wang X, Wang H, Wang C, Zhang H, Zhang G. Selenium (Na2SeO3) Upregulates Expression of Immune Genes and Blood-Testis Barrier Constituent Proteins of Bovine Sertoli Cell In Vitro. Biol Trace Elem Res. 2018;185:332-343 pubmed publisher
Sha Y, Zhang Y, Cao J, Qian K, Niu B, Chen Q. Loureirin B promotes insulin secretion through inhibition of KATP channel and influx of intracellular calcium. J Cell Biochem. 2018;119:2012-2021 pubmed publisher
Mikuła Pietrasik J, Uruski P, Szubert S, Maksin K, Moszyński R, Szpurek D, et al. The Proangiogenic Capabilities of Malignant Ascites Generated by Aggressive Ovarian Tumors. Biomed Res Int. 2017;2017:2592496 pubmed publisher
Bai Y, Su Z, Sun H, Zhao W, Chen X, Hang P, et al. Aloe-Emodin Relieves High-Fat Diet Induced QT Prolongation via MiR-1 Inhibition and IK1 Up-Regulation in Rats. Cell Physiol Biochem. 2017;43:1961-1973 pubmed publisher
He X, Li L, Tang M, Zeng Y, Li H, Yu X. Biomimetic electrical stimulation induces rat bone marrow mesenchymal stem cells to differentiate into cardiomyocyte-like cells via TGF-beta 1 in vitro. Prog Biophys Mol Biol. 2017;: pubmed publisher
Lee H, Chen C, Tsai W, Lin H, Shiao Y, Sheu S, et al. Very-Low-Density Lipoprotein of Metabolic Syndrome Modulates Gap Junctions and Slows Cardiac Conduction. Sci Rep. 2017;7:12050 pubmed publisher
Mikuła Pietrasik J, Uruski P, Pakuła M, Maksin K, Szubert S, Wozniak A, et al. Oxidative stress contributes to hepatocyte growth factor-dependent pro-senescence activity of ovarian cancer cells. Free Radic Biol Med. 2017;110:270-279 pubmed publisher
Jin Z, Ding Y, Xue R, Jia Z, Huang Z, Ding Y, et al. Involvement of interstitial cells of Cajal in bladder dysfunction in mice with experimental autoimmune encephalomyelitis. Int Urol Nephrol. 2017;49:1353-1359 pubmed publisher
Kong H, Liu X, Yang L, Qi K, Zhang H, Zhang J, et al. All-trans retinoic acid enhances bystander effect of suicide gene therapy in the treatment of breast cancer. Oncol Rep. 2016;35:1868-74 pubmed publisher
Liu X, Cao K, Xu C, Hu T, Zhou L, Cao D, et al. GATA-3 augmentation down-regulates Connexin43 in Helicobacter pylori associated gastric carcinogenesis. Cancer Biol Ther. 2015;16:987-96 pubmed publisher
Xue Y, Yan Y, Gong H, Fang B, Zhou Y, Ding Z, et al. Insulin-like growth factor binding protein 4 enhances cardiomyocytes induction in murine-induced pluripotent stem cells. J Cell Biochem. 2014;115:1495-504 pubmed publisher
product information
CatalogNo :
15386-1-AP
AntigenName :
Connexin-43
Package :
150 ul
Price :
299 USD
20ul trial size available :
20ul trial size available
FullName :
gap junction protein, alpha 1, 43kDa
Immunogen :
Fusion Protein
Species :
calf, cow, human, mouse, rat
Host :
Rabbit
IsConjugated :
Unconjugated
AntigenSpecies :
human
Application :
WB, IP, IHC, IF, FC, ELISA
Clonlity :
Polyclonal
IsoType :
IgG
Synonyms :
Connexin-43, CX43, DFNB38, Gap junction alpha 1 protein, GJA1, GJAL, ODDD
PrimaryOrSecondary :
Primary
AntibodyBuffer :
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
GenBankNo :
BC026329
Category :
Binding Proteins;Cytoskeleton/Scaffold Proteins;Membrane Proteins;Neurology;Signal transduction;Transport/Trafficking;
PurifyMethod :
Antigen affinity purification
IsSellable :
1
AppTiter :
FC 1:0 ; IF 1:50 ; IHC 1:100 ; IP 1:500 ; WB 1:1000 ;
company information
Proteintech Group
2201 W. Campbell Park Dr. STE12
Chicago, IL 60612
Proteintech@ptglab.com
https://www.ptglab.com
1-312-455-8498
headquarters: USA
At Proteintech, we produce every single antibody we sell; we do not rely on or supply to any other antibody providers: our products are unique and we are 100% accountable for each one. We realize this accountability by validating in-house, providing extensive technical support and guaranteeing your success: in addition to helping you troubleshoot your experiment, we will offer you a full cash refund if you are in any way dissatisfied. We can guarantee satisfaction because we have confidence in our products, confidence cultivated by the science behind our antibodies: we make them using as much of the native protein as possible, and purifying them using affinity purification with the original antigen. We carry out antibody production over a 102-day period, which allows for better antigen fitting to MHC molecules and affinity maturation in the host. This approach results in higher affinity antibodies with greater sensitivity, which you can use in any application and in multiple species.
You can only buy Proteintech antibodies directly from Proteintech or via one of its approved distributors — when you receive your antibody and see the Proteintech logo on the vial, know that you hold something that is truly unique.